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The map label for this gene is cysS [H]

Identifier: 18977396

GI number: 18977396

Start: 978478

End: 979929

Strand: Direct

Name: cysS [H]

Synonym: PF1024

Alternate gene names: 18977396

Gene position: 978478-979929 (Clockwise)

Preceding gene: 18977393

Following gene: 18977400

Centisome position: 51.28

GC content: 38.02

Gene sequence:

>1452_bases
GTGCCCAGGGGGAAGAATATGCTCAAGGTTTACAATACCTTAACGAAACAAAAGGAAGAATTTAAGCCCCTAAGGGAAGG
AGAAGTGAAAATGTACGTGTGTGGTCCCACAGTTTATGATTATCCTCACTTGGGACATGCAAGGACATACATAGCCTTTG
ACGTGATCAGGAGATATTTAGAACATAAAGGATACACCGTACTTATGGTGATGAACTTTACGGATATAGATGACAAGATA
ATCAAAAGAGCAAGAGAGACGGGAGAAGACCCAAAAGAGCTAGCTGAGAGATTTATAAAAATATTCCTTGAAGATATGGA
AGCATTAAAGGTAAAGCCTGCAGATATTTATCCTAGGGTTACAGATCACATAGACGATATTATAGAGTTCATTGGGAAGC
TTAAGGAAAAGGGATATGCTTATGAGGGAAGTGATGGAATTTACTTTGAAGTTAAAAAGTTTCCAGAATACGGAAAGCTT
AGCGGAGTAAAAATTGAGGATCTCCAAAAAGGAGCAAGAGTTGAACCTGGTGAAGGGAAGAAAAACCCTGAAGATTTCGC
CCTATGGAAAAAAGCAAAGCCAGGAGAACCCAAGTGGGATAGTCCATGGGGAGAGGGGAGACCTGGATGGCATATTGAAT
GTTCAGTCATGAGCAGTAAGTATCTTGGAGAAAGCTTTGATATTCATGGAGGAGGAAATGACTTAATATTCCCCCATCAT
GAAAATGAAATAGCTCAAAGCGAAGCATGCTTTGGTCATGAATGGGTTAAGTATTGGTTACATACAGGATTTGTTATGGT
AAAAGGAGAAAAGATGAGCAAGAGTTTAGGAAACTTCGTCACAATACGAGAATTATTAAAGAGATACGAACCAGAGGTGA
TAAGGTTCTTTGTTCTACAAAAGCACTATCGTTCTCCCCTTGAATATACAGAAGAAGGACTTCAACACGCAAAGAATAAT
CTACAGAGGCTTTACAATACCCTTGAAAACATAAGAGTCGCACTAAGGAATGCCGAAATATCTTATACCTGGGGAGAACT
GGAATTCAAGACATATGAGATAATTAGAGAAGGGAAAAGAAAATTCTATGAAGCTATGGATGACGATTTTAATACAGCAG
AAGCTCTTAAAGCAGTTTTTGAGGTAGCTAATGCAATAAATAAGTATCTAACGGAGGCTAATAAGCCGAAAGAGTCAATA
CTTAGGAAGGCTCTCGAATTCTTTAAGATCGTTAGTGAAGTTTTCGGAGTATTTGAAGATTATTTCAGAGAGGAAACAAA
AGAACGTGAAGAATCCGAAAAATTAATTGAACTCTTAGTAGAGGTCAGAAAACAACTTAGAAAGGAAAAGAGATACGAGT
TGGCAGATATGATTCGAGAAGAGCTTAAAAAATTAGGCATACAATTAGAAGATAGGGGAAGCGAAACAACTTGGAAGAGA
ATTATAACCTAG

Upstream 100 bases:

>100_bases
CTGAAGAGGTATCAGAAACTTAAACCTAACGTCCCACTGCTTATCCTGACAGTGTCGCTTGCCCTCATCGACACTCTAAT
AAATAGCCAAAACTAATACT

Downstream 100 bases:

>100_bases
TAAATGTCCTTTTCAATGATCACAATAGCTCTCCCTATAGAAATAGGATTTCCTTGACTTCTAATTTCTTCTTCGACATT
CTTTATTAGCTTCTTAATTT

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 483; Mature: 482

Protein sequence:

>483_residues
MPRGKNMLKVYNTLTKQKEEFKPLREGEVKMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHKGYTVLMVMNFTDIDDKI
IKRARETGEDPKELAERFIKIFLEDMEALKVKPADIYPRVTDHIDDIIEFIGKLKEKGYAYEGSDGIYFEVKKFPEYGKL
SGVKIEDLQKGARVEPGEGKKNPEDFALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHH
ENEIAQSEACFGHEWVKYWLHTGFVMVKGEKMSKSLGNFVTIRELLKRYEPEVIRFFVLQKHYRSPLEYTEEGLQHAKNN
LQRLYNTLENIRVALRNAEISYTWGELEFKTYEIIREGKRKFYEAMDDDFNTAEALKAVFEVANAINKYLTEANKPKESI
LRKALEFFKIVSEVFGVFEDYFREETKEREESEKLIELLVEVRKQLRKEKRYELADMIREELKKLGIQLEDRGSETTWKR
IIT

Sequences:

>Translated_483_residues
MPRGKNMLKVYNTLTKQKEEFKPLREGEVKMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHKGYTVLMVMNFTDIDDKI
IKRARETGEDPKELAERFIKIFLEDMEALKVKPADIYPRVTDHIDDIIEFIGKLKEKGYAYEGSDGIYFEVKKFPEYGKL
SGVKIEDLQKGARVEPGEGKKNPEDFALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHH
ENEIAQSEACFGHEWVKYWLHTGFVMVKGEKMSKSLGNFVTIRELLKRYEPEVIRFFVLQKHYRSPLEYTEEGLQHAKNN
LQRLYNTLENIRVALRNAEISYTWGELEFKTYEIIREGKRKFYEAMDDDFNTAEALKAVFEVANAINKYLTEANKPKESI
LRKALEFFKIVSEVFGVFEDYFREETKEREESEKLIELLVEVRKQLRKEKRYELADMIREELKKLGIQLEDRGSETTWKR
IIT
>Mature_482_residues
PRGKNMLKVYNTLTKQKEEFKPLREGEVKMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHKGYTVLMVMNFTDIDDKII
KRARETGEDPKELAERFIKIFLEDMEALKVKPADIYPRVTDHIDDIIEFIGKLKEKGYAYEGSDGIYFEVKKFPEYGKLS
GVKIEDLQKGARVEPGEGKKNPEDFALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHE
NEIAQSEACFGHEWVKYWLHTGFVMVKGEKMSKSLGNFVTIRELLKRYEPEVIRFFVLQKHYRSPLEYTEEGLQHAKNNL
QRLYNTLENIRVALRNAEISYTWGELEFKTYEIIREGKRKFYEAMDDDFNTAEALKAVFEVANAINKYLTEANKPKESIL
RKALEFFKIVSEVFGVFEDYFREETKEREESEKLIELLVEVRKQLRKEKRYELADMIREELKKLGIQLEDRGSETTWKRI
IT

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=516, Percent_Identity=39.3410852713178, Blast_Score=331, Evalue=1e-90,
Organism=Homo sapiens, GI303304987, Length=413, Percent_Identity=34.8668280871671, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI21269877, Length=413, Percent_Identity=34.8668280871671, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI62240992, Length=424, Percent_Identity=34.1981132075472, Blast_Score=240, Evalue=3e-63,
Organism=Homo sapiens, GI10835051, Length=424, Percent_Identity=34.1981132075472, Blast_Score=239, Evalue=3e-63,
Organism=Escherichia coli, GI1786737, Length=482, Percent_Identity=48.1327800829876, Blast_Score=431, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI17509797, Length=443, Percent_Identity=34.0857787810384, Blast_Score=221, Evalue=8e-58,
Organism=Caenorhabditis elegans, GI17509795, Length=443, Percent_Identity=34.0857787810384, Blast_Score=221, Evalue=9e-58,
Organism=Saccharomyces cerevisiae, GI6324082, Length=428, Percent_Identity=35.2803738317757, Blast_Score=239, Evalue=6e-64,
Organism=Drosophila melanogaster, GI19922218, Length=508, Percent_Identity=34.0551181102362, Blast_Score=280, Evalue=1e-75,
Organism=Drosophila melanogaster, GI19922364, Length=414, Percent_Identity=34.2995169082126, Blast_Score=232, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 56792; Mature: 56660

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRGKNMLKVYNTLTKQKEEFKPLREGEVKMYVCGPTVYDYPHLGHARTYIAFDVIRRYL
CCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
EHKGYTVLMVMNFTDIDDKIIKRARETGEDPKELAERFIKIFLEDMEALKVKPADIYPRV
HCCCCEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
TDHIDDIIEFIGKLKEKGYAYEGSDGIYFEVKKFPEYGKLSGVKIEDLQKGARVEPGEGK
HHHHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCCCC
KNPEDFALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHH
CCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCCEECCCCCCEECCCC
ENEIAQSEACFGHEWVKYWLHTGFVMVKGEKMSKSLGNFVTIRELLKRYEPEVIRFFVLQ
CCHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
KHYRSPLEYTEEGLQHAKNNLQRLYNTLENIRVALRNAEISYTWGELEFKTYEIIREGKR
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHH
KFYEAMDDDFNTAEALKAVFEVANAINKYLTEANKPKESILRKALEFFKIVSEVFGVFED
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YFREETKEREESEKLIELLVEVRKQLRKEKRYELADMIREELKKLGIQLEDRGSETTWKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHH
IIT
HCC
>Mature Secondary Structure 
PRGKNMLKVYNTLTKQKEEFKPLREGEVKMYVCGPTVYDYPHLGHARTYIAFDVIRRYL
CCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
EHKGYTVLMVMNFTDIDDKIIKRARETGEDPKELAERFIKIFLEDMEALKVKPADIYPRV
HCCCCEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
TDHIDDIIEFIGKLKEKGYAYEGSDGIYFEVKKFPEYGKLSGVKIEDLQKGARVEPGEGK
HHHHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCCCC
KNPEDFALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHH
CCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCCEECCCCCCEECCCC
ENEIAQSEACFGHEWVKYWLHTGFVMVKGEKMSKSLGNFVTIRELLKRYEPEVIRFFVLQ
CCHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
KHYRSPLEYTEEGLQHAKNNLQRLYNTLENIRVALRNAEISYTWGELEFKTYEIIREGKR
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHH
KFYEAMDDDFNTAEALKAVFEVANAINKYLTEANKPKESILRKALEFFKIVSEVFGVFED
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YFREETKEREESEKLIELLVEVRKQLRKEKRYELADMIREELKKLGIQLEDRGSETTWKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHH
IIT
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA