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The map label for this gene is pitA [C]

Identifier: 18977392

GI number: 18977392

Start: 975450

End: 976688

Strand: Direct

Name: pitA [C]

Synonym: PF1020

Alternate gene names: 18977392

Gene position: 975450-976688 (Clockwise)

Preceding gene: 18977391

Following gene: 18977393

Centisome position: 51.12

GC content: 41.65

Gene sequence:

>1239_bases
ATGCAACTGGGGTTCGCCATGCTTGCTGATCCAATTTTGTTAATTACGATACTTTTGGGATTTGCAATGGCCTGGGCAAT
AGGTGCAAATGATGCTGCTAATTCCATGAGCACCGCCGTAGGTGCAGGAGCAATAACACCCAGACAGGCCGTGATAATTG
CTGGAGTTCTTGAATTTATGGGAGCTTATTTCTTTGGAAAGACAGTTACAGAGACAATTAGAAAAGGCATCATCGATCCC
TCAAAAATTACAGATCCAAATGTCTTAATATTTGGCTCAATAGCGGCATTAATTGGTGCAACAATATGGCTAGTAATCGC
AACAAAATATGGACTTCCAGTATCTACTACTCACTCAATAATAGGGGGGATAGTGGGTTATGGAATTGTTTATGGAGGAA
TGTCAATAGTAAATTGGGATAAGATGATTAAAGTAGTTCTCAGTTGGATACTCTCCCCAATCGTCGGAGCAATCTTTGCA
TACCTAGTATTCAGAGCGCTAAGTAAAACGGTTCTTCAAAGCAAGGACCCTGTGAAAAGTGCAAAGAGATGGTCTCCATT
CTGGATAGGGCTAGCATTTGTGGTCATTGGAACAATGTTCTACATAAAGGTTCTACACGGTAATTCATTACTTGAAGGAT
TTCTCAAATACGGAATGCCAGCTGGAATTCTAACATTCATAGTAGTCTCCTTAATATTGGAAAAGAGATTTCCAGCCACT
GATCCCTATCTTGGAGCTGAGAGAGTATTTAGAAGGGTGCAGGTTATAACATCAGCATACGTTGCACTTGCCCACGGAGC
AAACGACGTTGCTAATGCAATAGGACCAGTGGCAGCAGTTTATACAGTGGCAATGTTCGGTCTTGCTGGAGCAAAGGTGC
CAGTTCCAAGGTGGATATTGGCCCTTGGAGGACTGGGAATAGCAATAGGTGTCGCAACTTATGGATATAAAGTTATGGAA
ACCGTTGGAAAGAAAATAACAGAGCTGACAAACACTAGAGGGTTTACAATAGACTTTTCAGCAGCTACGGTAGTTTTGAT
TGCCTCTTGGTTGGGGATGCCAATATCTACTACTCACACAGTAGTTGGTGCCGTAATTGGAGTTGGTCTTGCAAGAGGAA
TAAAAGCGATAAACAAGGATATAGTTAAGGACATAATAATCTCGTGGTTCGTTACAGTTCCAGCTGCAGGAGTAATAGCT
GGAATAATATTTAAGGCCTTAATGATGTTAATGGGGTGA

Upstream 100 bases:

>100_bases
ACCTAGGCCAATATACCATAGATATCTAATCAACGATCTATATAGAATACTGAGCTATATATTTTCTATAGCGGTAAAAT
ATTTATTTGGAGGGAAACAC

Downstream 100 bases:

>100_bases
TACCATGCAGGTTTGGACGAAACTCTTTGCTAAAAGTCCATTCAAGCCTCTTATAAAGCATGCAGAGGTTGTAGTTGAGA
CTGTAGAAACATTGGAAAAA

Product: putative phosphate transport protein pitb

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MQLGFAMLADPILLITILLGFAMAWAIGANDAANSMSTAVGAGAITPRQAVIIAGVLEFMGAYFFGKTVTETIRKGIIDP
SKITDPNVLIFGSIAALIGATIWLVIATKYGLPVSTTHSIIGGIVGYGIVYGGMSIVNWDKMIKVVLSWILSPIVGAIFA
YLVFRALSKTVLQSKDPVKSAKRWSPFWIGLAFVVIGTMFYIKVLHGNSLLEGFLKYGMPAGILTFIVVSLILEKRFPAT
DPYLGAERVFRRVQVITSAYVALAHGANDVANAIGPVAAVYTVAMFGLAGAKVPVPRWILALGGLGIAIGVATYGYKVME
TVGKKITELTNTRGFTIDFSAATVVLIASWLGMPISTTHTVVGAVIGVGLARGIKAINKDIVKDIIISWFVTVPAAGVIA
GIIFKALMMLMG

Sequences:

>Translated_412_residues
MQLGFAMLADPILLITILLGFAMAWAIGANDAANSMSTAVGAGAITPRQAVIIAGVLEFMGAYFFGKTVTETIRKGIIDP
SKITDPNVLIFGSIAALIGATIWLVIATKYGLPVSTTHSIIGGIVGYGIVYGGMSIVNWDKMIKVVLSWILSPIVGAIFA
YLVFRALSKTVLQSKDPVKSAKRWSPFWIGLAFVVIGTMFYIKVLHGNSLLEGFLKYGMPAGILTFIVVSLILEKRFPAT
DPYLGAERVFRRVQVITSAYVALAHGANDVANAIGPVAAVYTVAMFGLAGAKVPVPRWILALGGLGIAIGVATYGYKVME
TVGKKITELTNTRGFTIDFSAATVVLIASWLGMPISTTHTVVGAVIGVGLARGIKAINKDIVKDIIISWFVTVPAAGVIA
GIIFKALMMLMG
>Mature_412_residues
MQLGFAMLADPILLITILLGFAMAWAIGANDAANSMSTAVGAGAITPRQAVIIAGVLEFMGAYFFGKTVTETIRKGIIDP
SKITDPNVLIFGSIAALIGATIWLVIATKYGLPVSTTHSIIGGIVGYGIVYGGMSIVNWDKMIKVVLSWILSPIVGAIFA
YLVFRALSKTVLQSKDPVKSAKRWSPFWIGLAFVVIGTMFYIKVLHGNSLLEGFLKYGMPAGILTFIVVSLILEKRFPAT
DPYLGAERVFRRVQVITSAYVALAHGANDVANAIGPVAAVYTVAMFGLAGAKVPVPRWILALGGLGIAIGVATYGYKVME
TVGKKITELTNTRGFTIDFSAATVVLIASWLGMPISTTHTVVGAVIGVGLARGIKAINKDIVKDIIISWFVTVPAAGVIA
GIIFKALMMLMG

Specific function: Potential transporter for phosphate

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family

Homologues:

Organism=Homo sapiens, GI31543630, Length=182, Percent_Identity=40.6593406593407, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI5803173, Length=160, Percent_Identity=41.25, Blast_Score=136, Evalue=3e-32,
Organism=Escherichia coli, GI1789907, Length=199, Percent_Identity=30.1507537688442, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71981576, Length=444, Percent_Identity=33.5585585585586, Blast_Score=226, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17539280, Length=211, Percent_Identity=36.4928909952607, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17557328, Length=492, Percent_Identity=25.2032520325203, Blast_Score=138, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI25146401, Length=184, Percent_Identity=36.4130434782609, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI32566716, Length=233, Percent_Identity=32.618025751073, Blast_Score=121, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17536725, Length=165, Percent_Identity=38.7878787878788, Blast_Score=114, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6319773, Length=158, Percent_Identity=43.6708860759494, Blast_Score=135, Evalue=9e-33,
Organism=Drosophila melanogaster, GI21356511, Length=185, Percent_Identity=37.2972972972973, Blast_Score=135, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1020_PYRFU (Q8U230)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_578749.1
- ProteinModelPortal:   Q8U230
- EnsemblBacteria:   EBPYRT00000005298
- GeneID:   1468886
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF1020
- NMPDR:   fig|186497.1.peg.1057
- GeneTree:   EBGT00050000022387
- HOGENOM:   HBG681698
- OMA:   HISPRMA
- ProtClustDB:   CLSK865312
- InterPro:   IPR001204
- PANTHER:   PTHR11101

Pfam domain/function: PF01384 PHO4

EC number: NA

Molecular weight: Translated: 43573; Mature: 43573

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd112df8)-; HASH(0xdfab440)-; HASH(0xdb58330)-; HASH(0xe00ebac)-; HASH(0xd84a2ec)-; HASH(0xe08c1a8)-; HASH(0xe13942c)-; HASH(0xd7ecf60)-; HASH(0xd87eca0)-; HASH(0xd507a54)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA