Click here to switch to the map view.

The map label for this gene is iorA [H]

Identifier: 18977217

GI number: 18977217

Start: 817300

End: 819183

Strand: Reverse

Name: iorA [H]

Synonym: PF0845

Alternate gene names: 18977217

Gene position: 819183-817300 (Counterclockwise)

Preceding gene: 18977219

Following gene: 18977207

Centisome position: 42.93

GC content: 45.86

Gene sequence:

>1884_bases
ATGAAATTTTTAACTTTCGTGAATAGAGTAGACTGGTGGTTAAACGTGAAGAAGTTGCTTATGGGTAATGAAGCCATAGC
TTACGGAGCTTTGGAGGCTGGAGTTTCTTTTGCTACTGGTTATCCTGGGACTCCTTCTACGGAGGTTATAGAGACTATAG
CGAGATTGAAGCCAGAAGTTTTTGCGGAGTGGGCTCCAAATGAGAAGGTTGCTTTAGAAGAGGCCGCTGGAGTGTCTTAC
GCTGGACTGAGGAGTCTAGTTACCATGAAGTGTGTTGGACTAAACGTTGCGGCAGATCCCCTGATGAGCTTGGCATATTC
AGGAGTTGAGGGAGGGCTTGTAATTCTAGTTGCCGACGATCCTGGGCCCCATACAAGTCAAACAGAGCAAGATGACAGAT
ACTATGGAAAGCTTGCCTTACTACCAGTTCTTGAGCCTTATGATCCCCAGGAGGCTCATGATTTAATAATATACGCTTAC
GAACTCAGCGAGAAGTACAAGGTTCCAATAATATTTAGAACAACCACTAGGGTTAACCACACCACGGCAGACGTTGAAGT
TGGTGAGTTTAAGGAGCTTAAGAGAGAACCGAAGTTCAAGAAGGACATAGAGAGGTACGTTAGAGCAAGCATGGAGGGGA
ATAGGAAGAGACACAAGTGGCTCAACGAGACTTTGAAGAGAATAGAGGAGGAGTTCAACACATTGAGGTTCAACTGGATT
GAGGGAGAGGGAAGAGTTGGAATAATAGTCGAGGGAGCTCCATATAACTACGTTAAGGAGGTAGTTCCTCAGATAGAAGA
AGATTTCAAGATACTAAAGTTATCAACTCCTCACCCACTTCCCAGGAAGCTCGTTGTTGAGTTCCTTAGGAGCGTTGACG
TTGCCTTAGTCGTTGAGGAAGGAGCACCTTTCTTGGAGGAGGAGATCAAGGTAGTTGCATATGAAGAAGGCCTCAACGTT
CCAATATATGGAAAGAGAACCGGACATCTACCGTTGGAGGGAGAGCTAACGCCAAGACTCGTCAGAAACGCTATTCTAAA
GCTTTTGGGAAAGGAAAGGGAAGAGGTCAAGTTGCCCAAGGAAGTGGAAGAGGCAAAAGCTTTGGCTCCAAAGAGGCCTC
CAGTAATGTGCCCAGGCTGTCCCCACAGGGGGACTTATAGGGCCCTTCTAGATGCCCTAAGAGAATTAGGATATGGAAAG
TTCGATATCCCAATTCATGGAGACATTGGCTGTTATGCGCTATCCCTGCTCCCACCCCTAGAGGCAATATGGACAGAATT
CGTTATGGGGGCTAGTATAAGCTTGGCCAACGGACAAAGCGTAGCTATGGGTAAGAAGATAGTTGCCACAATAGGGGATT
CAACGTTCTTCCACAATGGAATCCAACCATTAATTGATGCAGTGTACAAGGACTTAGACGTCCTGGTGATAATCCTAGAC
AACAGAACAACTGCTATGACAGGTCATCAGCCGCACCCTGGGACTGGAGGAAGTGAAACTGGAAGGAAGTTCAGGGAGAT
AGACATAGAGTCTGTAGTTAGAGGAATAGGGGTTAAGTACGTTAAAACTGTCGATCCATACAATCTAAAGGAGACAAAAG
AGGCAATAAAGGAGGCTATGAAGGTTAAAGGACCTGCAGTTATTATAGCGAAGAGGGAATGTGTGATACCAGTCATAAGA
AGAGGGGAGATCGGAGAAATACCAGTGGTTGTGGAGGACAGGTGTACTGGATGTAAGGCCTGTATACTTTTAACTGGATG
TCCAGCGCTTGTTTATGAGCCAGAAAAGAAGAAGGTCAGGATTGACCCCTTGATATGTACAGGGTGTGGAGTGTGCAACC
AGCTCTGTCCATTTGATGCAATTAAGTTCCCAAGCGAGCTTTGA

Upstream 100 bases:

>100_bases
TGAAATAACTAATCCAGAAACCTTCTTCACTGGGGAAAAGGATGTGTATATTGTTCCATTTATGAGGGCCTTCATGCAAT
CACCTATATGTTTTACACCC

Downstream 100 bases:

>100_bases
TCTCTATTTTTATTATATCCCCCACCTCAAAATTTCCACCAATCAGCTTAACTCTCTCTTCGTTGCAGTAAACCCCAATC
CCTCTAACTTTAACACCGTT

Product: 2-keto acid:ferredoxin oxidoreductase subunit alpha

Products: NA

Alternate protein names: IOR; Indolepyruvate ferredoxin oxidoreductase subunit alpha [H]

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
MKFLTFVNRVDWWLNVKKLLMGNEAIAYGALEAGVSFATGYPGTPSTEVIETIARLKPEVFAEWAPNEKVALEEAAGVSY
AGLRSLVTMKCVGLNVAADPLMSLAYSGVEGGLVILVADDPGPHTSQTEQDDRYYGKLALLPVLEPYDPQEAHDLIIYAY
ELSEKYKVPIIFRTTTRVNHTTADVEVGEFKELKREPKFKKDIERYVRASMEGNRKRHKWLNETLKRIEEEFNTLRFNWI
EGEGRVGIIVEGAPYNYVKEVVPQIEEDFKILKLSTPHPLPRKLVVEFLRSVDVALVVEEGAPFLEEEIKVVAYEEGLNV
PIYGKRTGHLPLEGELTPRLVRNAILKLLGKEREEVKLPKEVEEAKALAPKRPPVMCPGCPHRGTYRALLDALRELGYGK
FDIPIHGDIGCYALSLLPPLEAIWTEFVMGASISLANGQSVAMGKKIVATIGDSTFFHNGIQPLIDAVYKDLDVLVIILD
NRTTAMTGHQPHPGTGGSETGRKFREIDIESVVRGIGVKYVKTVDPYNLKETKEAIKEAMKVKGPAVIIAKRECVIPVIR
RGEIGEIPVVVEDRCTGCKACILLTGCPALVYEPEKKKVRIDPLICTGCGVCNQLCPFDAIKFPSEL

Sequences:

>Translated_627_residues
MKFLTFVNRVDWWLNVKKLLMGNEAIAYGALEAGVSFATGYPGTPSTEVIETIARLKPEVFAEWAPNEKVALEEAAGVSY
AGLRSLVTMKCVGLNVAADPLMSLAYSGVEGGLVILVADDPGPHTSQTEQDDRYYGKLALLPVLEPYDPQEAHDLIIYAY
ELSEKYKVPIIFRTTTRVNHTTADVEVGEFKELKREPKFKKDIERYVRASMEGNRKRHKWLNETLKRIEEEFNTLRFNWI
EGEGRVGIIVEGAPYNYVKEVVPQIEEDFKILKLSTPHPLPRKLVVEFLRSVDVALVVEEGAPFLEEEIKVVAYEEGLNV
PIYGKRTGHLPLEGELTPRLVRNAILKLLGKEREEVKLPKEVEEAKALAPKRPPVMCPGCPHRGTYRALLDALRELGYGK
FDIPIHGDIGCYALSLLPPLEAIWTEFVMGASISLANGQSVAMGKKIVATIGDSTFFHNGIQPLIDAVYKDLDVLVIILD
NRTTAMTGHQPHPGTGGSETGRKFREIDIESVVRGIGVKYVKTVDPYNLKETKEAIKEAMKVKGPAVIIAKRECVIPVIR
RGEIGEIPVVVEDRCTGCKACILLTGCPALVYEPEKKKVRIDPLICTGCGVCNQLCPFDAIKFPSEL
>Mature_627_residues
MKFLTFVNRVDWWLNVKKLLMGNEAIAYGALEAGVSFATGYPGTPSTEVIETIARLKPEVFAEWAPNEKVALEEAAGVSY
AGLRSLVTMKCVGLNVAADPLMSLAYSGVEGGLVILVADDPGPHTSQTEQDDRYYGKLALLPVLEPYDPQEAHDLIIYAY
ELSEKYKVPIIFRTTTRVNHTTADVEVGEFKELKREPKFKKDIERYVRASMEGNRKRHKWLNETLKRIEEEFNTLRFNWI
EGEGRVGIIVEGAPYNYVKEVVPQIEEDFKILKLSTPHPLPRKLVVEFLRSVDVALVVEEGAPFLEEEIKVVAYEEGLNV
PIYGKRTGHLPLEGELTPRLVRNAILKLLGKEREEVKLPKEVEEAKALAPKRPPVMCPGCPHRGTYRALLDALRELGYGK
FDIPIHGDIGCYALSLLPPLEAIWTEFVMGASISLANGQSVAMGKKIVATIGDSTFFHNGIQPLIDAVYKDLDVLVIILD
NRTTAMTGHQPHPGTGGSETGRKFREIDIESVVRGIGVKYVKTVDPYNLKETKEAIKEAMKVKGPAVIIAKRECVIPVIR
RGEIGEIPVVVEDRCTGCKACILLTGCPALVYEPEKKKVRIDPLICTGCGVCNQLCPFDAIKFPSEL

Specific function: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates [H]

COG id: COG4231

COG function: function code C; Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR017721
- InterPro:   IPR002880
- InterPro:   IPR011766
- InterPro:   IPR009014
- InterPro:   IPR015941 [H]

Pfam domain/function: PF01855 POR_N; PF02775 TPP_enzyme_C [H]

EC number: =1.2.7.8 [H]

Molecular weight: Translated: 69661; Mature: 69661

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLTFVNRVDWWLNVKKLLMGNEAIAYGALEAGVSFATGYPGTPSTEVIETIARLKPEV
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHCCHHH
FAEWAPNEKVALEEAAGVSYAGLRSLVTMKCVGLNVAADPLMSLAYSGVEGGLVILVADD
HHCCCCCCCEEHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECC
PGPHTSQTEQDDRYYGKLALLPVLEPYDPQEAHDLIIYAYELSEKYKVPIIFRTTTRVNH
CCCCCCCCCCCHHHHCEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCEEEEEECCCCCC
TTADVEVGEFKELKREPKFKKDIERYVRASMEGNRKRHKWLNETLKRIEEEFNTLRFNWI
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCEEEEEEE
EGEGRVGIIVEGAPYNYVKEVVPQIEEDFKILKLSTPHPLPRKLVVEFLRSVDVALVVEE
ECCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEEC
GAPFLEEEIKVVAYEEGLNVPIYGKRTGHLPLEGELTPRLVRNAILKLLGKEREEVKLPK
CCCHHHHCCEEEEEECCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHCCCCH
EVEEAKALAPKRPPVMCPGCPHRGTYRALLDALRELGYGKFDIPIHGDIGCYALSLLPPL
HHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHCCCCEEECEECCCHHHHHHHHCCCH
EAIWTEFVMGASISLANGQSVAMGKKIVATIGDSTFFHNGIQPLIDAVYKDLDVLVIILD
HHHHHHHHHCCEEEECCCCCCHHCCEEEEEECCCHHHHCCHHHHHHHHHCCCEEEEEEEC
NRTTAMTGHQPHPGTGGSETGRKFREIDIESVVRGIGVKYVKTVDPYNLKETKEAIKEAM
CCEEEECCCCCCCCCCCCHHCCHHHHCCHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHH
KVKGPAVIIAKRECVIPVIRRGEIGEIPVVVEDRCTGCKACILLTGCPALVYEPEKKKVR
HCCCCEEEEEECCCEEHHCCCCCCCCCCEEECCCCCCCEEEEEEECCCCEEECCCCCCEE
IDPLICTGCGVCNQLCPFDAIKFPSEL
ECCEEECCCHHHHHCCCCHHCCCCCCC
>Mature Secondary Structure
MKFLTFVNRVDWWLNVKKLLMGNEAIAYGALEAGVSFATGYPGTPSTEVIETIARLKPEV
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHCCHHH
FAEWAPNEKVALEEAAGVSYAGLRSLVTMKCVGLNVAADPLMSLAYSGVEGGLVILVADD
HHCCCCCCCEEHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECC
PGPHTSQTEQDDRYYGKLALLPVLEPYDPQEAHDLIIYAYELSEKYKVPIIFRTTTRVNH
CCCCCCCCCCCHHHHCEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCEEEEEECCCCCC
TTADVEVGEFKELKREPKFKKDIERYVRASMEGNRKRHKWLNETLKRIEEEFNTLRFNWI
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCEEEEEEE
EGEGRVGIIVEGAPYNYVKEVVPQIEEDFKILKLSTPHPLPRKLVVEFLRSVDVALVVEE
ECCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEEC
GAPFLEEEIKVVAYEEGLNVPIYGKRTGHLPLEGELTPRLVRNAILKLLGKEREEVKLPK
CCCHHHHCCEEEEEECCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHCCCCH
EVEEAKALAPKRPPVMCPGCPHRGTYRALLDALRELGYGKFDIPIHGDIGCYALSLLPPL
HHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHCCCCEEECEECCCHHHHHHHHCCCH
EAIWTEFVMGASISLANGQSVAMGKKIVATIGDSTFFHNGIQPLIDAVYKDLDVLVIILD
HHHHHHHHHCCEEEECCCCCCHHCCEEEEEECCCHHHHCCHHHHHHHHHCCCEEEEEEEC
NRTTAMTGHQPHPGTGGSETGRKFREIDIESVVRGIGVKYVKTVDPYNLKETKEAIKEAM
CCEEEECCCCCCCCCCCCHHCCHHHHCCHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHH
KVKGPAVIIAKRECVIPVIRRGEIGEIPVVVEDRCTGCKACILLTGCPALVYEPEKKKVR
HCCCCEEEEEECCCEEHHCCCCCCCCCCEEECCCCCCCEEEEEEECCCCEEECCCCCCEE
IDPLICTGCGVCNQLCPFDAIKFPSEL
ECCEEECCCHHHHHCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]