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The map label for this gene is ygcA [C]

Identifier: 18977199

GI number: 18977199

Start: 806556

End: 807785

Strand: Reverse

Name: ygcA [C]

Synonym: PF0827

Alternate gene names: 18977199

Gene position: 807785-806556 (Counterclockwise)

Preceding gene: 18977200

Following gene: 18977198

Centisome position: 42.33

GC content: 42.76

Gene sequence:

>1230_bases
ATGAGGGGAATAATTGAAGATTTATCCCAGGATGGCCTTGGAGTTATTAATGGCATTGAAGTTCCCTTCTGCTACCCAGG
GGATGAGGTAAGAATAACGAGAACTAGGGATAGATTTGGAAGAAAGATGGCCTCAGAATTTTCACTCATAACCCCTTCTC
CCCTTAGACAAAGGCCGAGGTGCAGGCATTACGGAAAATGTGGTGGTTGCTTATGGCAGGGAATGAAATATGAGGAGCAA
CTAAAATTCAAGAAAGAGCTCTTTAGGAGAATTACTGGAATTGAAGCGGAAATACTTGGTTCGCCCAGGATTTGGGAGTT
TAGGAATATAAGCAACTTCATAGTTTCGGTAAACGGGATAGGACTTAAAGAATTTGCGAGGCCAAAGACGGTTGTCGATT
TAAAAGAGTGTCCAGTCTTCTCCAACAGGACTCCACTATATATAAGGGCAATGAAGGAATTTCTTAGGGAAAGCGGGCTA
AAACCATGGAACTGGAAGGAGGGAGACGTTCACTATCTACAAGTTAGAGAGGGAAAGTTTACAGGTGAAGTTATGGTAAA
CATAATAGCCCATAGGCCCCCTGAAGAAACCATTCTAGAGTACTTCCCGTTTGCAGACTCAGTATACTGGAGCATAAAGA
GGGATAAAAGAGATGACCCTTCAGGAGAGCCAATTCATCTTGGAGAGAAAGAATTTATATCCGAGAAAATTTTTGGAATT
AAATATCTCCTTCGCCCTGGGATCTTCTTCCAGACAAACAGCTATGCCCTCCCTCTACTCTTAAAAGCAGTTGAAGGGTT
CTTGGACGGATCTAAGGTGCTTGACCTCTACTCTGGAATCGGGACGTTCTCATTATACTTGACCAAGAAGGGATTCAACG
TGGTGGGGGTAGAAATAAACAAGACTGCAGTTGAGGTTGCGAAGTTATCAGCTGAGCTAAACTCCCTCAACGTTGAATTC
AAGGCCAAAAGGGCCGAAGAGGAAAATATTGAAGGGTACGACGCCTTGATTTTAGACCCTCCCAGGAAGGGGTTAGGAGA
ATTTGCGGGAGTTGTGGAGAAAAAAGGGCCTGAGAATGTAGTTTATGTATCATGCAATCCAAAGAGATTCATATTGGATT
TCAAAAACTATCTATCAAGGTCTTACAAAGTGGAGGATGCAATTCTCATAGACATGTTTCCCCACACTCCCCATGTGGAA
GCTGTGATTAAGCTAAGGAAATATTCATAA

Upstream 100 bases:

>100_bases
TGTTTAAGTATAAGATCGTTGTTGACAAAGCAAAAAAAGTGTGGGAGCCCTGCACTTCTTCCGGAAAGCTAATAATTGAA
GAGGCCCATCTTGAATCAAA

Downstream 100 bases:

>100_bases
GTAGACCAACCCTCCTGTAAACCATGAAGGAGATCCTCCTTTTAGCTCTCATAAGCCTCGGCTGGATATTTAACTACTCT
CACAGGATGGCCGTTCCAGC

Product: putative RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MRGIIEDLSQDGLGVINGIEVPFCYPGDEVRITRTRDRFGRKMASEFSLITPSPLRQRPRCRHYGKCGGCLWQGMKYEEQ
LKFKKELFRRITGIEAEILGSPRIWEFRNISNFIVSVNGIGLKEFARPKTVVDLKECPVFSNRTPLYIRAMKEFLRESGL
KPWNWKEGDVHYLQVREGKFTGEVMVNIIAHRPPEETILEYFPFADSVYWSIKRDKRDDPSGEPIHLGEKEFISEKIFGI
KYLLRPGIFFQTNSYALPLLLKAVEGFLDGSKVLDLYSGIGTFSLYLTKKGFNVVGVEINKTAVEVAKLSAELNSLNVEF
KAKRAEEENIEGYDALILDPPRKGLGEFAGVVEKKGPENVVYVSCNPKRFILDFKNYLSRSYKVEDAILIDMFPHTPHVE
AVIKLRKYS

Sequences:

>Translated_409_residues
MRGIIEDLSQDGLGVINGIEVPFCYPGDEVRITRTRDRFGRKMASEFSLITPSPLRQRPRCRHYGKCGGCLWQGMKYEEQ
LKFKKELFRRITGIEAEILGSPRIWEFRNISNFIVSVNGIGLKEFARPKTVVDLKECPVFSNRTPLYIRAMKEFLRESGL
KPWNWKEGDVHYLQVREGKFTGEVMVNIIAHRPPEETILEYFPFADSVYWSIKRDKRDDPSGEPIHLGEKEFISEKIFGI
KYLLRPGIFFQTNSYALPLLLKAVEGFLDGSKVLDLYSGIGTFSLYLTKKGFNVVGVEINKTAVEVAKLSAELNSLNVEF
KAKRAEEENIEGYDALILDPPRKGLGEFAGVVEKKGPENVVYVSCNPKRFILDFKNYLSRSYKVEDAILIDMFPHTPHVE
AVIKLRKYS
>Mature_409_residues
MRGIIEDLSQDGLGVINGIEVPFCYPGDEVRITRTRDRFGRKMASEFSLITPSPLRQRPRCRHYGKCGGCLWQGMKYEEQ
LKFKKELFRRITGIEAEILGSPRIWEFRNISNFIVSVNGIGLKEFARPKTVVDLKECPVFSNRTPLYIRAMKEFLRESGL
KPWNWKEGDVHYLQVREGKFTGEVMVNIIAHRPPEETILEYFPFADSVYWSIKRDKRDDPSGEPIHLGEKEFISEKIFGI
KYLLRPGIFFQTNSYALPLLLKAVEGFLDGSKVLDLYSGIGTFSLYLTKKGFNVVGVEINKTAVEVAKLSAELNSLNVEF
KAKRAEEENIEGYDALILDPPRKGLGEFAGVVEKKGPENVVYVSCNPKRFILDFKNYLSRSYKVEDAILIDMFPHTPHVE
AVIKLRKYS

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RNA M5U methyltransferase family

Homologues:

Organism=Homo sapiens, GI34222389, Length=359, Percent_Identity=27.8551532033426, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI51173878, Length=359, Percent_Identity=27.8551532033426, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI269784680, Length=471, Percent_Identity=25.4777070063694, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI269784676, Length=471, Percent_Identity=25.4777070063694, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI20149688, Length=471, Percent_Identity=25.4777070063694, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI269784678, Length=445, Percent_Identity=25.6179775280899, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI1789148, Length=422, Percent_Identity=26.7772511848341, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1787083, Length=377, Percent_Identity=26.525198938992, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790403, Length=180, Percent_Identity=31.6666666666667, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24666579, Length=365, Percent_Identity=27.1232876712329, Blast_Score=101, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y827_PYRFU (Q8U2K7)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_578556.1
- ProteinModelPortal:   Q8U2K7
- SMR:   Q8U2K7
- EnsemblBacteria:   EBPYRT00000005959
- GeneID:   1468683
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF0827
- NMPDR:   fig|186497.1.peg.854
- GeneTree:   EBGT00050000022236
- HOGENOM:   HBG690163
- OMA:   FADSLYW
- ProtClustDB:   CLSK253194
- InterPro:   IPR010280

Pfam domain/function: PF05958 tRNA_U5-meth_tr

EC number: NA

Molecular weight: Translated: 46869; Mature: 46869

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS01230 TRMA_1; PS01231 TRMA_2

Important sites: ACT_SITE 365-365 BINDING 251-251 BINDING 277-277 BINDING 298-298 BINDING 339-339

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGIIEDLSQDGLGVINGIEVPFCYPGDEVRITRTRDRFGRKMASEFSLITPSPLRQRPR
CCCHHHHHCCCCCCEEECCCCEEECCCCCEEEEECHHHHHHHHHHHCCCCCCCHHHCCCC
CRHYGKCGGCLWQGMKYEEQLKFKKELFRRITGIEAEILGSPRIWEFRNISNFIVSVNGI
HHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCEEEECCCCEEEEEECCC
GLKEFARPKTVVDLKECPVFSNRTPLYIRAMKEFLRESGLKPWNWKEGDVHYLQVREGKF
CHHHHCCCCCEEEHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCC
TGEVMVNIIAHRPPEETILEYFPFADSVYWSIKRDKRDDPSGEPIHLGEKEFISEKIFGI
CHHHHHHHHHCCCCHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEECCHHHHHHHHHHHH
KYLLRPGIFFQTNSYALPLLLKAVEGFLDGSKVLDLYSGIGTFSLYLTKKGFNVVGVEIN
HHHHCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEECCCEEEEEEEC
KTAVEVAKLSAELNSLNVEFKAKRAEEENIEGYDALILDPPRKGLGEFAGVVEKKGPENV
HHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCE
VYVSCNPKRFILDFKNYLSRSYKVEDAILIDMFPHTPHVEAVIKLRKYS
EEEEECCCEEEEEHHHHHCCCCCCCCEEEEEECCCCCCHHHHHEECCCC
>Mature Secondary Structure
MRGIIEDLSQDGLGVINGIEVPFCYPGDEVRITRTRDRFGRKMASEFSLITPSPLRQRPR
CCCHHHHHCCCCCCEEECCCCEEECCCCCEEEEECHHHHHHHHHHHCCCCCCCHHHCCCC
CRHYGKCGGCLWQGMKYEEQLKFKKELFRRITGIEAEILGSPRIWEFRNISNFIVSVNGI
HHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCEEEECCCCEEEEEECCC
GLKEFARPKTVVDLKECPVFSNRTPLYIRAMKEFLRESGLKPWNWKEGDVHYLQVREGKF
CHHHHCCCCCEEEHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCC
TGEVMVNIIAHRPPEETILEYFPFADSVYWSIKRDKRDDPSGEPIHLGEKEFISEKIFGI
CHHHHHHHHHCCCCHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEECCHHHHHHHHHHHH
KYLLRPGIFFQTNSYALPLLLKAVEGFLDGSKVLDLYSGIGTFSLYLTKKGFNVVGVEIN
HHHHCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEECCCEEEEEEEC
KTAVEVAKLSAELNSLNVEFKAKRAEEENIEGYDALILDPPRKGLGEFAGVVEKKGPENV
HHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCE
VYVSCNPKRFILDFKNYLSRSYKVEDAILIDMFPHTPHVEAVIKLRKYS
EEEEECCCEEEEEHHHHHCCCCCCCCEEEEEECCCCCCHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA