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The map label for this gene is mshA [H]

Identifier: 18977163

GI number: 18977163

Start: 776880

End: 778049

Strand: Reverse

Name: mshA [H]

Synonym: PF0791

Alternate gene names: 18977163

Gene position: 778049-776880 (Counterclockwise)

Preceding gene: 18977164

Following gene: 18977162

Centisome position: 40.77

GC content: 37.01

Gene sequence:

>1170_bases
ATGAGGGTTCTGGTGATGGTAAATGACTTTCCGAATAAAGATAATTCTTATACAGCCAATATATTTGTCAAAGAACAAGT
CAAGGCACTATCAGAATTCGTTGAAGAGATCAACGTCATAGTTCCAATACCACGAGGAATTGAATTATACAGAAAAACTT
CATACAGAGATTATGCGATTGGAGAAAATGTTCACGTTCACTTTGTGAAATACATAAATCCCTTGTTTCCCATAGCGTAT
TCAAAGCTTCGAAGGGAGTGGATATGGCTTGAGCACAGAGCACTGACAAATTTCATAAAAAAGAAAGACATTAAATTTGA
TATCATCCACGCTCACTATACTTGGCCAAGTGGTGCAGTTGGAGTAAAATTAAAAGAGGAATACAAGGTTCCGTTAGTCA
TAACGGAGCATACTTCGCAAACATTTAACAGGTATATTACTACTAGAGATCCTTTGGCACGAGAAATATGGCAAAAGGCA
GACATAATAGTTAGGGTGCGGAAGGGTGATATCGATTTATTTAGTAGAGTAGGTATTACACCAAGCAAAATACGATATAT
TCCCAATGGGTTTGATGGGAACAAATTTTATCCGATACCTCAAGAAATAGCTCGTAGAAAGTTGAATCTGGTTGAATATG
AGAAGATCATTATTAATGTTGCTAACATGTACTCACGTGTTAAAGGTCATGAATATCTTTTAAGAGCATTTTCCAAAGTG
GCTGAAAATACTTCAGATGCGTTTTTAATACTCGTTGGTAGCGGGAAGTTGCTATCACACCTAAAAAAGCTTGCTGATAA
TTTATATCTTGGACATCGTGTTTTGTTCGCAGGTTCAAAACCTCACGATGAAATTCCACTATGGATGAATGCTGCTGATT
TGTTTGTTTTGCCGAGTTTGAGAGAAAGCTTTGGAGTAGTTCAAATTGAAGCTATGGCATGCGGAGTTCCAGTTGTAGCT
ACGAGAAATGGTGGTAGTGAAGAGATAATAATTTCTGAAGATTATGGGTTACTTTGTGAGCCGGCGAATCCAAAAGAGTT
AGCAGAGAAAATTTTAATTGCCTTAGAGAAAGAATGGGATAGAGAAAAGATAAGAAAGTATGCTGAGCAGTTCACATGGG
AGAATATTGCGAAAAAGACTTTAGAAGTTTACAGAGGTGTGCTGAAATGA

Upstream 100 bases:

>100_bases
TGCTAAGCCTCTGCTGAGAAAAATGAATCGCAAATGGTATCTTTCGGAGTTTAATGGAATCGTTGCAGAGTGGTGCTTGG
CTAACTTGGAGGGAGTATAG

Downstream 100 bases:

>100_bases
ATAACATTCGAATTTTTAAATTCCTTGTAATTTTGTATTCTCTGCTGTTAATAGCATCATCTTTTGTTTATTATTACCGA
GAAGATATTTACATACGACC

Product: hypothetical protein

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MRVLVMVNDFPNKDNSYTANIFVKEQVKALSEFVEEINVIVPIPRGIELYRKTSYRDYAIGENVHVHFVKYINPLFPIAY
SKLRREWIWLEHRALTNFIKKKDIKFDIIHAHYTWPSGAVGVKLKEEYKVPLVITEHTSQTFNRYITTRDPLAREIWQKA
DIIVRVRKGDIDLFSRVGITPSKIRYIPNGFDGNKFYPIPQEIARRKLNLVEYEKIIINVANMYSRVKGHEYLLRAFSKV
AENTSDAFLILVGSGKLLSHLKKLADNLYLGHRVLFAGSKPHDEIPLWMNAADLFVLPSLRESFGVVQIEAMACGVPVVA
TRNGGSEEIIISEDYGLLCEPANPKELAEKILIALEKEWDREKIRKYAEQFTWENIAKKTLEVYRGVLK

Sequences:

>Translated_389_residues
MRVLVMVNDFPNKDNSYTANIFVKEQVKALSEFVEEINVIVPIPRGIELYRKTSYRDYAIGENVHVHFVKYINPLFPIAY
SKLRREWIWLEHRALTNFIKKKDIKFDIIHAHYTWPSGAVGVKLKEEYKVPLVITEHTSQTFNRYITTRDPLAREIWQKA
DIIVRVRKGDIDLFSRVGITPSKIRYIPNGFDGNKFYPIPQEIARRKLNLVEYEKIIINVANMYSRVKGHEYLLRAFSKV
AENTSDAFLILVGSGKLLSHLKKLADNLYLGHRVLFAGSKPHDEIPLWMNAADLFVLPSLRESFGVVQIEAMACGVPVVA
TRNGGSEEIIISEDYGLLCEPANPKELAEKILIALEKEWDREKIRKYAEQFTWENIAKKTLEVYRGVLK
>Mature_389_residues
MRVLVMVNDFPNKDNSYTANIFVKEQVKALSEFVEEINVIVPIPRGIELYRKTSYRDYAIGENVHVHFVKYINPLFPIAY
SKLRREWIWLEHRALTNFIKKKDIKFDIIHAHYTWPSGAVGVKLKEEYKVPLVITEHTSQTFNRYITTRDPLAREIWQKA
DIIVRVRKGDIDLFSRVGITPSKIRYIPNGFDGNKFYPIPQEIARRKLNLVEYEKIIINVANMYSRVKGHEYLLRAFSKV
AENTSDAFLILVGSGKLLSHLKKLADNLYLGHRVLFAGSKPHDEIPLWMNAADLFVLPSLRESFGVVQIEAMACGVPVVA
TRNGGSEEIIISEDYGLLCEPANPKELAEKILIALEKEWDREKIRKYAEQFTWENIAKKTLEVYRGVLK

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=288, Percent_Identity=26.0416666666667, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788357, Length=252, Percent_Identity=25.3968253968254, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790061, Length=217, Percent_Identity=25.3456221198157, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17532709, Length=288, Percent_Identity=23.6111111111111, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI9755344, Length=329, Percent_Identity=23.7082066869301, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 44980; Mature: 44980

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLVMVNDFPNKDNSYTANIFVKEQVKALSEFVEEINVIVPIPRGIELYRKTSYRDYAI
CEEEEEEECCCCCCCCEEEEEEEHHHHHHHHHHHHHCCEEEECCCCHHHHHHCCCCCEEC
GENVHVHFVKYINPLFPIAYSKLRREWIWLEHRALTNFIKKKDIKFDIIHAHYTWPSGAV
CCCCEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCE
GVKLKEEYKVPLVITEHTSQTFNRYITTRDPLAREIWQKADIIVRVRKGDIDLFSRVGIT
EEEECCCCCCCEEEECCCHHHHHHHCCCCCHHHHHHHCCCCEEEEEECCCCHHHHHCCCC
PSKIRYIPNGFDGNKFYPIPQEIARRKLNLVEYEKIIINVANMYSRVKGHEYLLRAFSKV
HHHEEECCCCCCCCEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
AENTSDAFLILVGSGKLLSHLKKLADNLYLGHRVLFAGSKPHDEIPLWMNAADLFVLPSL
HCCCCCEEEEEEECCHHHHHHHHHHHHHEECEEEEEECCCCCCCCCEEECCCCEEEECCH
RESFGVVQIEAMACGVPVVATRNGGSEEIIISEDYGLLCEPANPKELAEKILIALEKEWD
HHHCCEEEEEEEECCCCEEEECCCCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHCCCC
REKIRKYAEQFTWENIAKKTLEVYRGVLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVLVMVNDFPNKDNSYTANIFVKEQVKALSEFVEEINVIVPIPRGIELYRKTSYRDYAI
CEEEEEEECCCCCCCCEEEEEEEHHHHHHHHHHHHHCCEEEECCCCHHHHHHCCCCCEEC
GENVHVHFVKYINPLFPIAYSKLRREWIWLEHRALTNFIKKKDIKFDIIHAHYTWPSGAV
CCCCEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCE
GVKLKEEYKVPLVITEHTSQTFNRYITTRDPLAREIWQKADIIVRVRKGDIDLFSRVGIT
EEEECCCCCCCEEEECCCHHHHHHHCCCCCHHHHHHHCCCCEEEEEECCCCHHHHHCCCC
PSKIRYIPNGFDGNKFYPIPQEIARRKLNLVEYEKIIINVANMYSRVKGHEYLLRAFSKV
HHHEEECCCCCCCCEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
AENTSDAFLILVGSGKLLSHLKKLADNLYLGHRVLFAGSKPHDEIPLWMNAADLFVLPSL
HCCCCCEEEEEEECCHHHHHHHHHHHHHEECEEEEEECCCCCCCCCEEECCCCEEEECCH
RESFGVVQIEAMACGVPVVATRNGGSEEIIISEDYGLLCEPANPKELAEKILIALEKEWD
HHHCCEEEEEEEECCCCEEEECCCCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHCCCC
REKIRKYAEQFTWENIAKKTLEVYRGVLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA