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The map label for this gene is pepQ [H]

Identifier: 18977074

GI number: 18977074

Start: 707219

End: 707740

Strand: Direct

Name: pepQ [H]

Synonym: PF0702

Alternate gene names: 18977074

Gene position: 707219-707740 (Clockwise)

Preceding gene: 18977073

Following gene: 18977079

Centisome position: 37.06

GC content: 53.83

Gene sequence:

>522_bases
ATGCTTAACGGGAGCGAGAAGCCAAAAGTTTACGTCTCCGCAACGCCAAAGGCCCATGCTGAGCCCTTCAAAGATGTTAG
GATTAGGGAGGGAAGCGTTGTATCCGTTGTCATAGGTGCCGACTGGAACCACTACTACGCCAACATGACGAGGTACTTCC
CGATAGGCCAGATGAGCGAGAGGGCGAAAAACGCTATGGACGCGATGGAAGAAGCTTATGCCATCTCCGTCGAGAAAACG
AGGCCCGGTGTGAGGTTTGCACAGGTGGAGCGGGAAATCCAGAAGCTCTACTCATCCAGGGGGCTTGGGGAGTATTACAT
AACCGGCTACACCCACGGCGTCGGCCTTCTCATCGAAGAAGACCCGATAACGACCATAGTGGTTCCGCACAGGGCGATGG
AGGCCAAGGAGAACATGGTGCTGGCTATGGTTCACGCCCCGCTGATGATCCCCGAAGGGGCAGTAAAGAAGGAAGATACC
TTCATACTGGGCAGAAAGCTGGAGAACGTGACAAAGTATTAA

Upstream 100 bases:

>100_bases
AAGCCGGCAAAATAGCCGTGAATGGCATGAGAATCGCGGAAGGGGAGATAAGGCCCGGAAAGACGGAGCTTGAGGTTGCT
TCTGAGGTAGTTAGGAGCTC

Downstream 100 bases:

>100_bases
AAAGGCCGGGAAACTCAGAAACTTCCGCTTCCAAGGCCGCATATCTTCGCGAACGGACAGATAGAGCAGTCTTCCGTGTA
CGGCTCCAACGGCGGCTCTC

Product: x-pro dipeptidase

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MLNGSEKPKVYVSATPKAHAEPFKDVRIREGSVVSVVIGADWNHYYANMTRYFPIGQMSERAKNAMDAMEEAYAISVEKT
RPGVRFAQVEREIQKLYSSRGLGEYYITGYTHGVGLLIEEDPITTIVVPHRAMEAKENMVLAMVHAPLMIPEGAVKKEDT
FILGRKLENVTKY

Sequences:

>Translated_173_residues
MLNGSEKPKVYVSATPKAHAEPFKDVRIREGSVVSVVIGADWNHYYANMTRYFPIGQMSERAKNAMDAMEEAYAISVEKT
RPGVRFAQVEREIQKLYSSRGLGEYYITGYTHGVGLLIEEDPITTIVVPHRAMEAKENMVLAMVHAPLMIPEGAVKKEDT
FILGRKLENVTKY
>Mature_173_residues
MLNGSEKPKVYVSATPKAHAEPFKDVRIREGSVVSVVIGADWNHYYANMTRYFPIGQMSERAKNAMDAMEEAYAISVEKT
RPGVRFAQVEREIQKLYSSRGLGEYYITGYTHGVGLLIEEDPITTIVVPHRAMEAKENMVLAMVHAPLMIPEGAVKKEDT
FILGRKLENVTKY

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 19482; Mature: 19482

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNGSEKPKVYVSATPKAHAEPFKDVRIREGSVVSVVIGADWNHYYANMTRYFPIGQMSE
CCCCCCCCEEEEEECCCCCCCCCCCEEECCCCEEEEEEECCCCHHHHCEEEECCCCHHHH
RAKNAMDAMEEAYAISVEKTRPGVRFAQVEREIQKLYSSRGLGEYYITGYTHGVGLLIEE
HHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEEEEC
DPITTIVVPHRAMEAKENMVLAMVHAPLMIPEGAVKKEDTFILGRKLENVTKY
CCCEEEEECCHHHHCCCCEEEEEEECCEECCCCCCCCCCEEEECCHHHHHCCC
>Mature Secondary Structure
MLNGSEKPKVYVSATPKAHAEPFKDVRIREGSVVSVVIGADWNHYYANMTRYFPIGQMSE
CCCCCCCCEEEEEECCCCCCCCCCCEEECCCCEEEEEEECCCCHHHHCEEEECCCCHHHH
RAKNAMDAMEEAYAISVEKTRPGVRFAQVEREIQKLYSSRGLGEYYITGYTHGVGLLIEE
HHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEEEEC
DPITTIVVPHRAMEAKENMVLAMVHAPLMIPEGAVKKEDTFILGRKLENVTKY
CCCEEEEECCHHHHCCCCEEEEEEECCEECCCCCCCCCCEEEECCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9733678; 11223522; 11210522 [H]