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The map label for this gene is 18977060

Identifier: 18977060

GI number: 18977060

Start: 699079

End: 699579

Strand: Direct

Name: 18977060

Synonym: PF0688

Alternate gene names: NA

Gene position: 699079-699579 (Clockwise)

Preceding gene: 33359499

Following gene: 18977061

Centisome position: 36.63

GC content: 45.91

Gene sequence:

>501_bases
ATGTCCCTAGGAGGATCTGCAGATGATACTTACCTTCACGAGATCATTAAGAAGGCCTACGAAGCGGGAATAGTTATAGT
TGCAGCGGCTGGCAATGAAGGAGCCTCTAGCCCAAGTTATCCAGCAGCCTATCCTGAAGTAATTGCAGTAGGGGCTACTG
ATATAAATGACCAAGTCCCGTACTGGAGCAATCGTCAGCCAGAAGTTAGCGCTCCAGGTGTTGATATACTTAGCACTTAT
CCAGACGACACTTATGAAACTCTTTCAGGTACAAGTATGGCAACTCCTCACGTAAGTGGTGTTGTTGCGCTAATTCAAGC
TGCATACTATCTCAAGTACGGCAAAGTACTTCCAGTTGGAACATTTGACGATATGAGTACCAATACAGTTAGAGGAATTC
TGCACTTGGCAGTTGATGACCTCGGTGACCCTGGCTGGGATATCTACTATGGATACGGAATAATAAGGGCTGACAAGGCC
ATTCAACTTGCGCTCTTCTGA

Upstream 100 bases:

>100_bases
AAAAGAATTGAAAGTTCTTGGTCCAGATGGTATTGCAGATAAGGACGGAGATGGAATTATTGCAGGTGATCCGGACGATG
ACGCTGCAGAAGTCATAAGT

Downstream 100 bases:

>100_bases
TTTTTTTATTATATATTATGAAAATAGGTCTACAACTTTTTGGATCTATCTTTAGGAGGTCAATTTTTGAATGGAAGTTC
CTACAGGTACTGCAGAGGGT

Product: subtilisin-like protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MSLGGSADDTYLHEIIKKAYEAGIVIVAAAGNEGASSPSYPAAYPEVIAVGATDINDQVPYWSNRQPEVSAPGVDILSTY
PDDTYETLSGTSMATPHVSGVVALIQAAYYLKYGKVLPVGTFDDMSTNTVRGILHLAVDDLGDPGWDIYYGYGIIRADKA
IQLALF

Sequences:

>Translated_166_residues
MSLGGSADDTYLHEIIKKAYEAGIVIVAAAGNEGASSPSYPAAYPEVIAVGATDINDQVPYWSNRQPEVSAPGVDILSTY
PDDTYETLSGTSMATPHVSGVVALIQAAYYLKYGKVLPVGTFDDMSTNTVRGILHLAVDDLGDPGWDIYYGYGIIRADKA
IQLALF
>Mature_165_residues
SLGGSADDTYLHEIIKKAYEAGIVIVAAAGNEGASSPSYPAAYPEVIAVGATDINDQVPYWSNRQPEVSAPGVDILSTYP
DDTYETLSGTSMATPHVSGVVALIQAAYYLKYGKVLPVGTFDDMSTNTVRGILHLAVDDLGDPGWDIYYGYGIIRADKAI
QLALF

Specific function: Has a broad substrate specificity with a slight preference to large hydrophobic amino acid residues at the P1 position [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320775, Length=107, Percent_Identity=44.8598130841121, Blast_Score=74, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 17654; Mature: 17523

Theoretical pI: Translated: 4.07; Mature: 4.07

Prosite motif: PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLGGSADDTYLHEIIKKAYEAGIVIVAAAGNEGASSPSYPAAYPEVIAVGATDINDQVP
CCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCCC
YWSNRQPEVSAPGVDILSTYPDDTYETLSGTSMATPHVSGVVALIQAAYYLKYGKVLPVG
CCCCCCCCCCCCCCEEEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECC
TFDDMSTNTVRGILHLAVDDLGDPGWDIYYGYGIIRADKAIQLALF
CCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECEEEEECCEEEEEEC
>Mature Secondary Structure 
SLGGSADDTYLHEIIKKAYEAGIVIVAAAGNEGASSPSYPAAYPEVIAVGATDINDQVP
CCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCCC
YWSNRQPEVSAPGVDILSTYPDDTYETLSGTSMATPHVSGVVALIQAAYYLKYGKVLPVG
CCCCCCCCCCCCCCEEEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECC
TFDDMSTNTVRGILHLAVDDLGDPGWDIYYGYGIIRADKAIQLALF
CCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECEEEEECCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11375149 [H]