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The map label for this gene is hypA

Identifier: 18976987

GI number: 18976987

Start: 635673

End: 636092

Strand: Direct

Name: hypA

Synonym: PF0615

Alternate gene names: 18976987

Gene position: 635673-636092 (Clockwise)

Preceding gene: 18976986

Following gene: 18976988

Centisome position: 33.31

GC content: 45.71

Gene sequence:

>420_bases
ATGCACGAATGGGCGTTGGCAGATGCAATAGTAAGGACTGTTTTAGATTACGCTCAAAAGGAGGGTGCAAGTAGGGTAAA
GGCCGTCAAGGTAGTCCTCGGAGAACTCCAAGATGTTGGGGAGGATATAGTAAAGTTTGCCATGGAAGAGCTCTTCAGGG
GAACAATAGCGGAAGGGGCAGAGATAATATTCGAAGAGGAAGAGGCCGTCTTTAAGTGCCGCAACTGCGGGCATGTATGG
AAGCTTAAGGAAGTCAAAGATAAGTTGGATGAGAGGATAAGAGAGGACATCCACTTTATTCCAGAGGTCGTTCATGCATT
TCTATCCTGTCCAAAATGTGGAAGCCATGATTTTGAAGTGGTGAAGGGAAGGGGAGTTTACATTTCTGGAATAATGATCG
AGAAGGAGGGAGAAGAATGA

Upstream 100 bases:

>100_bases
GAAAGGTTGGGCTGAAGACAATAGATGATGTAAAAATAGTCAGAGATTGAACAATGCAGTTTTAAAAGGTCTAGAAGTAA
GGGGATAGTGGGGAAGAATA

Downstream 100 bases:

>100_bases
TAGATCCCAGAGAACTCGCAATTTCAGCGAAGCTTGAGGGAGTAAAAAGAATAATCCCAGTTGTAAGTGGGAAGGGAGGA
GTAGGAAAATCCCTAATCTC

Product: hydrogenase nickel incorporation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MHEWALADAIVRTVLDYAQKEGASRVKAVKVVLGELQDVGEDIVKFAMEELFRGTIAEGAEIIFEEEEAVFKCRNCGHVW
KLKEVKDKLDERIREDIHFIPEVVHAFLSCPKCGSHDFEVVKGRGVYISGIMIEKEGEE

Sequences:

>Translated_139_residues
MHEWALADAIVRTVLDYAQKEGASRVKAVKVVLGELQDVGEDIVKFAMEELFRGTIAEGAEIIFEEEEAVFKCRNCGHVW
KLKEVKDKLDERIREDIHFIPEVVHAFLSCPKCGSHDFEVVKGRGVYISGIMIEKEGEE
>Mature_139_residues
MHEWALADAIVRTVLDYAQKEGASRVKAVKVVLGELQDVGEDIVKFAMEELFRGTIAEGAEIIFEEEEAVFKCRNCGHVW
KLKEVKDKLDERIREDIHFIPEVVHAFLSCPKCGSHDFEVVKGRGVYISGIMIEKEGEE

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_PYRFU (Q8U357)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_578344.1
- ProteinModelPortal:   Q8U357
- EnsemblBacteria:   EBPYRT00000005842
- GeneID:   1468459
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF0615
- NMPDR:   fig|186497.1.peg.630
- GeneTree:   EBGT00050000023288
- HOGENOM:   HBG688671
- OMA:   HEWALAD
- ProtClustDB:   PRK03824
- HAMAP:   MF_00213
- InterPro:   IPR000688
- InterPro:   IPR020538
- InterPro:   IPR004039
- Gene3D:   G3DSA:2.20.28.10

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 15763; Mature: 15763

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEWALADAIVRTVLDYAQKEGASRVKAVKVVLGELQDVGEDIVKFAMEELFRGTIAEGA
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EIIFEEEEAVFKCRNCGHVWKLKEVKDKLDERIREDIHFIPEVVHAFLSCPKCGSHDFEV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
VKGRGVYISGIMIEKEGEE
EECCCEEEEEEEEECCCCC
>Mature Secondary Structure
MHEWALADAIVRTVLDYAQKEGASRVKAVKVVLGELQDVGEDIVKFAMEELFRGTIAEGA
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EIIFEEEEAVFKCRNCGHVWKLKEVKDKLDERIREDIHFIPEVVHAFLSCPKCGSHDFEV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
VKGRGVYISGIMIEKEGEE
EECCCEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA