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The map label for this gene is hypE [C]

Identifier: 18976976

GI number: 18976976

Start: 626147

End: 627118

Strand: Reverse

Name: hypE [C]

Synonym: PF0604

Alternate gene names: 18976976

Gene position: 627118-626147 (Counterclockwise)

Preceding gene: 33359491

Following gene: 18976971

Centisome position: 32.86

GC content: 45.99

Gene sequence:

>972_bases
ATGGAAGAACTAATTAGGGAGGTAATCCTCAAGAATTTAACCCTTAATTCTGCTGGAGGAATAGGATTAGAGGAGCTTGA
TGACGGAGCTACAATCCCCCTTGGAGATAAGCATTTAGTGTTTACAATAGATGGGCATACAGTAAAGCCGATATTCTTCC
CAGGGGGAGACATCGGAAGGTTGGCCGTTAGCGGAACTGTAAACGATTTGGCTGTCATGGGAGCTCAACCCTTGGCAATT
GCAAGCTCGTTGATAATCGAGGAAGGGTTTGAAGTTAGTGAGCTGGAAAAGATTCTGAAGTCGATGGACGAAACAGCTAA
AGAGGTTCCAGTTCCAATTGTTACTGGAGACACAAAAGTCGTTGAAGACAGGATAGGAATCTTCGTTATAACAGCTGGAG
TGGGGGTAGCTGAGAGGCCGATAAGCGATGCCGGCGCAAAAGTTGGGGATGTCGTTTTAGTGAGTGGAACAATTGGAGAC
CACGGAATAGCACTAATGAGCCATAGAGAGGGGATCTCCTTTGAGACAGAGCTTAAGAGCGATGTAGCTCCAATTTGGGA
TGTCGTAAAGGCCGTTGCAGATGCCATTGGTTGGGAGAACATCCACGCAATGAAAGATCCCACAAGAGGAGGATTGAGCA
ACGCACTAAACGAGATGGCAAGAAAGGCAAACGTTGGAATTTTGGTAAGAGAGGAGGCAATACCAATTAGGCCAGAAGTA
AAAGCTGCCAGCGAAATGCTTGGAATAAGTCCCTATGAAGTTGCAAACGAAGGAAAAGTTGTAATGATAGTGGCGAAGGA
GTATGCGGAGGAGGCACTTGAGGCCATGAAGAAGACAGAAAAGGGTAGGGATGCCGCAATAATAGGAGAAGTTATTGGTG
AATACAGAGGAAAAGTTATTCTGGAGACGGGAATTGGTGGAAGAAGATTTTTAGAGCCGCCTCTCGGTGATCCCGTTCCT
AGAGTTTGTTAG

Upstream 100 bases:

>100_bases
TTCCTCTCCCTGGGCATAATGATTTTAATAACCCTTGCCTAACACTAGCTTGGGATGCAAAATGAGAATCAGGCTTGAGC
ATGGAGCCGGAGGAGAATTA

Downstream 100 bases:

>100_bases
CCTTTATCTTTTTGTCCATTTTCAACATCTCCCTCCACTGCCTCCCTGGCCAGTAAATTTGGCCACAACTTGTGCAAATG
TAGAATTCATTATATGAATT

Product: hydrogenase expression/formation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MEELIREVILKNLTLNSAGGIGLEELDDGATIPLGDKHLVFTIDGHTVKPIFFPGGDIGRLAVSGTVNDLAVMGAQPLAI
ASSLIIEEGFEVSELEKILKSMDETAKEVPVPIVTGDTKVVEDRIGIFVITAGVGVAERPISDAGAKVGDVVLVSGTIGD
HGIALMSHREGISFETELKSDVAPIWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKANVGILVREEAIPIRPEV
KAASEMLGISPYEVANEGKVVMIVAKEYAEEALEAMKKTEKGRDAAIIGEVIGEYRGKVILETGIGGRRFLEPPLGDPVP
RVC

Sequences:

>Translated_323_residues
MEELIREVILKNLTLNSAGGIGLEELDDGATIPLGDKHLVFTIDGHTVKPIFFPGGDIGRLAVSGTVNDLAVMGAQPLAI
ASSLIIEEGFEVSELEKILKSMDETAKEVPVPIVTGDTKVVEDRIGIFVITAGVGVAERPISDAGAKVGDVVLVSGTIGD
HGIALMSHREGISFETELKSDVAPIWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKANVGILVREEAIPIRPEV
KAASEMLGISPYEVANEGKVVMIVAKEYAEEALEAMKKTEKGRDAAIIGEVIGEYRGKVILETGIGGRRFLEPPLGDPVP
RVC
>Mature_323_residues
MEELIREVILKNLTLNSAGGIGLEELDDGATIPLGDKHLVFTIDGHTVKPIFFPGGDIGRLAVSGTVNDLAVMGAQPLAI
ASSLIIEEGFEVSELEKILKSMDETAKEVPVPIVTGDTKVVEDRIGIFVITAGVGVAERPISDAGAKVGDVVLVSGTIGD
HGIALMSHREGISFETELKSDVAPIWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKANVGILVREEAIPIRPEV
KAASEMLGISPYEVANEGKVVMIVAKEYAEEALEAMKKTEKGRDAAIIGEVIGEYRGKVILETGIGGRRFLEPPLGDPVP
RVC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=330, Percent_Identity=38.7878787878788, Blast_Score=213, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 34271; Mature: 34271

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEELIREVILKNLTLNSAGGIGLEELDDGATIPLGDKHLVFTIDGHTVKPIFFPGGDIGR
CHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCCCE
LAVSGTVNDLAVMGAQPLAIASSLIIEEGFEVSELEKILKSMDETAKEVPVPIVTGDTKV
EEECCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCHH
VEDRIGIFVITAGVGVAERPISDAGAKVGDVVLVSGTIGDHGIALMSHREGISFETELKS
HHCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHH
DVAPIWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKANVGILVREEAIPIRPEV
CHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCH
KAASEMLGISPYEVANEGKVVMIVAKEYAEEALEAMKKTEKGRDAAIIGEVIGEYRGKVI
HHHHHHHCCCCHHCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEE
LETGIGGRRFLEPPLGDPVPRVC
EEECCCCCEECCCCCCCCCCCCC
>Mature Secondary Structure
MEELIREVILKNLTLNSAGGIGLEELDDGATIPLGDKHLVFTIDGHTVKPIFFPGGDIGR
CHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCCCE
LAVSGTVNDLAVMGAQPLAIASSLIIEEGFEVSELEKILKSMDETAKEVPVPIVTGDTKV
EEECCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCHH
VEDRIGIFVITAGVGVAERPISDAGAKVGDVVLVSGTIGDHGIALMSHREGISFETELKS
HHCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHH
DVAPIWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKANVGILVREEAIPIRPEV
CHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCH
KAASEMLGISPYEVANEGKVVMIVAKEYAEEALEAMKKTEKGRDAAIIGEVIGEYRGKVI
HHHHHHHCCCCHHCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEE
LETGIGGRRFLEPPLGDPVPRVC
EEECCCCCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]