| Definition | Pyrococcus furiosus DSM 3638, complete genome. |
|---|---|
| Accession | NC_003413 |
| Length | 1,908,256 |
Click here to switch to the map view.
The map label for this gene is hypF [H]
Identifier: 18976931
GI number: 18976931
Start: 575593
End: 577932
Strand: Direct
Name: hypF [H]
Synonym: PF0559
Alternate gene names: 18976931
Gene position: 575593-577932 (Clockwise)
Preceding gene: 18976930
Following gene: 18976933
Centisome position: 30.16
GC content: 44.83
Gene sequence:
>2340_bases ATGTATCTGGGGGAGAGAATGAAAGCTTATAGAATTCACGTTCAGGGAATAGTTCAGGCCGTGGGATTTAGGCCCTTCGT TTATAGAATAGCTCATGCTCACAACTTGAGGGGATACGTTAGGAACTTAGGCGATGCTGGAGTTGAAATTGTTGTCGAGG GAAGGGAGGAAGACATAGAGGCATTCATCAAGGATTTATACAAGAAGAAACCCCCACTTGCAAGGATTGATAAGGTTGAG AGGGAGGAAATTCCTCTTCAGGGCTTTGACAGATTTTACATAGAGAAAAGCTCGACGGAAAAGAAGGGGGAGGGAGATTC AATAATCCCTCCGGACATAGCTATTTGTGAGGACTGTCTTAGGGAGTTATTTAATCCAACTGACAAGCGCTACATGTATC CTTTCATAGTATGTACAAACTGTGGGCCGAGGTTCACGATAATTGAAGATCTTCCCTACGATAGGGAGAACACAGCGATG AGAGAATTCCCGATGTGCGAGTTCTGTAGGAGTGAATACGAGGATCCCCTGAATAGGAGGTATCATGCAGAGCCGGTTGC ATGTCCAACTTGTGGGCCGAGCTATAGGCTTTACACGAGCGATGGAAATGAGATAATTGGAGACCCCCTGAGAAAGGCGG CAAAACTAATCGATAAGGGATACATAGTTGCGATAAAGGGTATAGGTGGAATTCATTTGGCCTGCGATGCTACAAGAGAG GATGTGGTGGCCGAGCTTAGGAAGAGGATTTTTAGGCCTCAGAAGCCTTTCGCCATTATGGCCAAAGATTTAGAAACTGT AAGGACTTTTGCCTATATTTCTCCCGAAGAGGAGGAAGAATTAACAAGCTATAGAAGGCCAATAGTGGCTTTGAAGAAGA AGGAGCCCTTCCCACTTCCCGAAAACCTCGCTCCTGGGCTTCACACAATTGGGGTAATGCTTCCCTATGCTGGAACCCAC TACATATTATTCCACTGGAGCAAGACTCCAGTTTACGTTATGACTTCCGCAAACTTCCCAGGGATGCCGATGATAAAGGA CAATGAAGAGGCATTTGAAAAGCTTAGGGACGTTGCTGACTACCTCTTGCTCCACAATAGGAGAATTCCAAATAGAGCTG ACGATAGCGTTGTTCGCTTTGTAGATGGTAGAAGAGCTGTTATTAGGAGGAGCAGAGGATTTGTTCCACTTGGAATAGAG ATTCCATTTGAGTACAAAGGATTGGCAGTTGGTGCTGAGTTAATGAATGCTTTCGGAGTTGTTAAGAATGGAAAAGTTTA TCCAAGTCAGTACATAGGGGATACATCAAAGATTGAAGTTTTAGAGTTTATGAGGGAAGCCGTGAGGCACTTCTTCAAGA TATTGAGAGTTGATAACTTAGATCTAGTTGTTGCAGATTTGCATCCAAGCTACAACACAACTAAGCTGGGAATGGAGATC GCTGAGGAATTTGGGGCAGAATTCCTTCAAGTTCAACATCACTACGCTCACGTGGCCTCTGTAATGGCTGAGCACAACTT GGAGGAAGTTGTTGGAATTGCTCTAGATGGTGTTGGGTATGGAACCGACGGAAAAACTTGGGGTGGGGAAGTAATATATC TAAGCTATGAAGATGTGGAGAGGTTGGCCCACATAGAGTATTATCCACTCCCAGGAGGGGATTTGGCCAGCTACTATCCC TTGAGGGCCTTAATTGGAATACTCAGCTTAAACCACGACTTAGAGGAAGTTGAGAAAATCATAAGGGAGTTCTGTCCAAA TGCAATAAAGAGCTTAAAGTATGGGGAAACAGAGTTTAGGGTAATTATGAGGCAACTCAGCAGCGGGATAAACGTTGCCT ATGCCTCTTCAACGGGAAGGGTGCTTGATGCCTTCTCGGTACTTTTGAACGTTTCCTACAGGAGGCACTATGAGGGAGAG CCTGCGATGAAGCTGGAGAGCTTTGCATACCAAGGAAAGAACGATCTAAAGCTCACGGCTCCAATTGAAGGTGAGGAAAT AAAGGTTTCAGAGTTGTTTGAGGAAGTTCTTGAGCTGATGGGCAAGGCCAATCCTAAAGACATAGCTTACTCCGTTCACT TAGCCTTAGCTAGGGCATTTGCTGAAGTTAGCGTGGAGAAAGCTAAGGAGTTTGGAGCTAAAACTGTCGTTTTGGGTGGG GGAGTAGGGTACAATGAGCTAATAGTTAAGACGATAAGAAAGATAGTAGAGGGGAGAGGGCTAAGGTTCTTAACAACTTA CGAAGTTCCCAGGGGAGATAATGGAATTAATGTAGGCCAGGCCTTCCTGGGAGGATTGTACTTGGAAGGATACTTAAATA GGGAAGATTTGAGCATTTAG
Upstream 100 bases:
>100_bases GGGCATGATCTGTGATGAGGGTGTTTAACCAAAGGTTGAAAATCCCCCTTCTGTTTCTAACTTTTGGTTTTAGAAACCTA TAAAGGCTCCAAATTCGGAG
Downstream 100 bases:
>100_bases TTTGTCTCTACCTAGGCCTTCCTTTTTTTCTTAAATTATTCCATACATATTTTGCAGGTCTTGGGATATACTAATAGCGT TCTCCTTAATTACATTCACG
Product: hydrogenase expression/formation regulatory protein
Products: NA
Alternate protein names: Carbamoyl phosphate-converting enzyme hypF; [NiFe]-hydrogenase maturation factor hypF; Hydrogenase maturation protein hypF [H]
Number of amino acids: Translated: 779; Mature: 779
Protein sequence:
>779_residues MYLGERMKAYRIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEAFIKDLYKKKPPLARIDKVE REEIPLQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFNPTDKRYMYPFIVCTNCGPRFTIIEDLPYDRENTAM REFPMCEFCRSEYEDPLNRRYHAEPVACPTCGPSYRLYTSDGNEIIGDPLRKAAKLIDKGYIVAIKGIGGIHLACDATRE DVVAELRKRIFRPQKPFAIMAKDLETVRTFAYISPEEEEELTSYRRPIVALKKKEPFPLPENLAPGLHTIGVMLPYAGTH YILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLRDVADYLLLHNRRIPNRADDSVVRFVDGRRAVIRRSRGFVPLGIE IPFEYKGLAVGAELMNAFGVVKNGKVYPSQYIGDTSKIEVLEFMREAVRHFFKILRVDNLDLVVADLHPSYNTTKLGMEI AEEFGAEFLQVQHHYAHVASVMAEHNLEEVVGIALDGVGYGTDGKTWGGEVIYLSYEDVERLAHIEYYPLPGGDLASYYP LRALIGILSLNHDLEEVEKIIREFCPNAIKSLKYGETEFRVIMRQLSSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGE PAMKLESFAYQGKNDLKLTAPIEGEEIKVSELFEEVLELMGKANPKDIAYSVHLALARAFAEVSVEKAKEFGAKTVVLGG GVGYNELIVKTIRKIVEGRGLRFLTTYEVPRGDNGINVGQAFLGGLYLEGYLNREDLSI
Sequences:
>Translated_779_residues MYLGERMKAYRIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEAFIKDLYKKKPPLARIDKVE REEIPLQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFNPTDKRYMYPFIVCTNCGPRFTIIEDLPYDRENTAM REFPMCEFCRSEYEDPLNRRYHAEPVACPTCGPSYRLYTSDGNEIIGDPLRKAAKLIDKGYIVAIKGIGGIHLACDATRE DVVAELRKRIFRPQKPFAIMAKDLETVRTFAYISPEEEEELTSYRRPIVALKKKEPFPLPENLAPGLHTIGVMLPYAGTH YILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLRDVADYLLLHNRRIPNRADDSVVRFVDGRRAVIRRSRGFVPLGIE IPFEYKGLAVGAELMNAFGVVKNGKVYPSQYIGDTSKIEVLEFMREAVRHFFKILRVDNLDLVVADLHPSYNTTKLGMEI AEEFGAEFLQVQHHYAHVASVMAEHNLEEVVGIALDGVGYGTDGKTWGGEVIYLSYEDVERLAHIEYYPLPGGDLASYYP LRALIGILSLNHDLEEVEKIIREFCPNAIKSLKYGETEFRVIMRQLSSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGE PAMKLESFAYQGKNDLKLTAPIEGEEIKVSELFEEVLELMGKANPKDIAYSVHLALARAFAEVSVEKAKEFGAKTVVLGG GVGYNELIVKTIRKIVEGRGLRFLTTYEVPRGDNGINVGQAFLGGLYLEGYLNREDLSI >Mature_779_residues MYLGERMKAYRIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEAFIKDLYKKKPPLARIDKVE REEIPLQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFNPTDKRYMYPFIVCTNCGPRFTIIEDLPYDRENTAM REFPMCEFCRSEYEDPLNRRYHAEPVACPTCGPSYRLYTSDGNEIIGDPLRKAAKLIDKGYIVAIKGIGGIHLACDATRE DVVAELRKRIFRPQKPFAIMAKDLETVRTFAYISPEEEEELTSYRRPIVALKKKEPFPLPENLAPGLHTIGVMLPYAGTH YILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLRDVADYLLLHNRRIPNRADDSVVRFVDGRRAVIRRSRGFVPLGIE IPFEYKGLAVGAELMNAFGVVKNGKVYPSQYIGDTSKIEVLEFMREAVRHFFKILRVDNLDLVVADLHPSYNTTKLGMEI AEEFGAEFLQVQHHYAHVASVMAEHNLEEVVGIALDGVGYGTDGKTWGGEVIYLSYEDVERLAHIEYYPLPGGDLASYYP LRALIGILSLNHDLEEVEKIIREFCPNAIKSLKYGETEFRVIMRQLSSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGE PAMKLESFAYQGKNDLKLTAPIEGEEIKVSELFEEVLELMGKANPKDIAYSVHLALARAFAEVSVEKAKEFGAKTVVLGG GVGYNELIVKTIRKIVEGRGLRFLTTYEVPRGDNGINVGQAFLGGLYLEGYLNREDLSI
Specific function: Along with hypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carb
COG id: COG0068
COG function: function code O; Hydrogenase maturation factor
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 YrdC-like domain [H]
Homologues:
Organism=Escherichia coli, GI2367152, Length=771, Percent_Identity=37.3540856031128, Blast_Score=426, Evalue=1e-120,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001792 - InterPro: IPR017968 - InterPro: IPR004421 - InterPro: IPR017945 - InterPro: IPR006070 - InterPro: IPR011125 [H]
Pfam domain/function: PF00708 Acylphosphatase; PF01300 Sua5_yciO_yrdC; PF07503 zf-HYPF [H]
EC number: NA
Molecular weight: Translated: 88162; Mature: 88162
Theoretical pI: Translated: 5.97; Mature: 5.97
Prosite motif: PS51160 ACYLPHOSPHATASE_3 ; PS51163 YRDC
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MYLGERMKAYRIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIE CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHH AFIKDLYKKKPPLARIDKVEREEIPLQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCL HHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHH RELFNPTDKRYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCEFCRSEYEDPLNRR HHHCCCCCCCEEEEEEEEECCCCCEEEEECCCCCCCCCHHHHCCHHHHHHHHCCCHHHCC YHAEPVACPTCGPSYRLYTSDGNEIIGDPLRKAAKLIDKGYIVAIKGIGGIHLACDATRE CCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEECCCCEEEEECCCHH DVVAELRKRIFRPQKPFAIMAKDLETVRTFAYISPEEEEELTSYRRPIVALKKKEPFPLP HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEECCCCCCCC ENLAPGLHTIGVMLPYAGTHYILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLRDVAD CCCCCCHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCCCEECCHHHHHHHHHHHH YLLLHNRRIPNRADDSVVRFVDGRRAVIRRSRGFVPLGIEIPFEYKGLAVGAELMNAFGV HHHHHCCCCCCCCCCHHHHHHCCCHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCC VKNGKVYPSQYIGDTSKIEVLEFMREAVRHFFKILRVDNLDLVVADLHPSYNTTKLGMEI CCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHH AEEFGAEFLQVQHHYAHVASVMAEHNLEEVVGIALDGVGYGTDGKTWGGEVIYLSYEDVE HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEECCCCCCCCCEEEEEEHHHHH RLAHIEYYPLPGGDLASYYPLRALIGILSLNHDLEEVEKIIREFCPNAIKSLKYGETEFR HHHHCEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHCCCCCHHHH VIMRQLSSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLESFAYQGKNDLKLTA HHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEC PIEGEEIKVSELFEEVLELMGKANPKDIAYSVHLALARAFAEVSVEKAKEFGAKTVVLGG CCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC GVGYNELIVKTIRKIVEGRGLRFLTTYEVPRGDNGINVGQAFLGGLYLEGYLNREDLSI CCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHCCCCEECCCCCCCCCC >Mature Secondary Structure MYLGERMKAYRIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIE CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHH AFIKDLYKKKPPLARIDKVEREEIPLQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCL HHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHH RELFNPTDKRYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCEFCRSEYEDPLNRR HHHCCCCCCCEEEEEEEEECCCCCEEEEECCCCCCCCCHHHHCCHHHHHHHHCCCHHHCC YHAEPVACPTCGPSYRLYTSDGNEIIGDPLRKAAKLIDKGYIVAIKGIGGIHLACDATRE CCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEECCCCEEEEECCCHH DVVAELRKRIFRPQKPFAIMAKDLETVRTFAYISPEEEEELTSYRRPIVALKKKEPFPLP HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEECCCCCCCC ENLAPGLHTIGVMLPYAGTHYILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLRDVAD CCCCCCHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCCCEECCHHHHHHHHHHHH YLLLHNRRIPNRADDSVVRFVDGRRAVIRRSRGFVPLGIEIPFEYKGLAVGAELMNAFGV HHHHHCCCCCCCCCCHHHHHHCCCHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCC VKNGKVYPSQYIGDTSKIEVLEFMREAVRHFFKILRVDNLDLVVADLHPSYNTTKLGMEI CCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHH AEEFGAEFLQVQHHYAHVASVMAEHNLEEVVGIALDGVGYGTDGKTWGGEVIYLSYEDVE HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEECCCCCCCCCEEEEEEHHHHH RLAHIEYYPLPGGDLASYYPLRALIGILSLNHDLEEVEKIIREFCPNAIKSLKYGETEFR HHHHCEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHCCCCCHHHH VIMRQLSSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLESFAYQGKNDLKLTA HHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEC PIEGEEIKVSELFEEVLELMGKANPKDIAYSVHLALARAFAEVSVEKAKEFGAKTVVLGG CCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC GVGYNELIVKTIRKIVEGRGLRFLTTYEVPRGDNGINVGQAFLGGLYLEGYLNREDLSI CCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHCCCCEECCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8688087 [H]