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The map label for this gene is 18976924

Identifier: 18976924

GI number: 18976924

Start: 568808

End: 570007

Strand: Reverse

Name: 18976924

Synonym: PF0552

Alternate gene names: NA

Gene position: 570007-568808 (Counterclockwise)

Preceding gene: 18976927

Following gene: 18976919

Centisome position: 29.87

GC content: 41.25

Gene sequence:

>1200_bases
ATGGGCGAGAAAAAGGGGTTAAGCTTCTTTGAAAAGTATCTCTCACTTTGGGTTGCTCTTTGTATAGTACTCGGCATTCT
AATTGGAAAATTCATGCCATCCCTTCCCAGAACACTTTCAAAGCTCACAATAGCAAACGTAAATATGGCAATAGCAGTAC
TAATTTGGGCAATGATTTATCCAATGATGGTCAAGGTTGACTTTTCAGCAATTAAGAGAGTGCACAAGGGCCAAATGCTC
AAGGGATTAATTGTTACTTGGGTAACCAACTGGTTAATAAAGCCATTCAGTATGTTCCTAATAAGTTCATTCTTCATAGG
CACTATTTTTTCAATGAAGCTTGGCCTCATTGATCCCTCTCTTGCCAAGGAGTACATAGCAGGTGCAATACTTTTGGGAG
CTGCACCCTGTACTGCGATGGTTTTCGTGTGGAGTTATTTAGCTGATGGAGACCCCCTCTACACTTTAGTGCAGGTAGCA
ACAAACGACATTATAATTCTCTTCGCATTCGCTCCAATAGTTGGTTTCCTCATGGGTCTTAACAAAGTTCCAGTTCCATA
TGATACACTCCTCCTCTCCGTAGTACTCTTTGTTGTAATCCCACTGTCCGCTGGCTACCTTTCAAGAAGATACATTTTGA
AGACAAAAGGACACAAATGGTTTGAGCAAGAGTTTCTTCCAAAGCTTAGCACAATATCAATAGTTGGATTGTTGCTCACT
TTAATTCTGCTGTTCTCGTTCCAGGGAGAGATAATCCTCGAAAATCCACTCCACATTGCCCTCATAGCTATTCCCCTAAC
AATACAGACGTACTTTATATTTGCAATAGCCTATGGATGGGCATGGATCTGGAAACTCCCACACAAGGTTGCCGCTCCAG
CATCATTCATAGGTGCAAGCAACTTTTTCGAACTGGCCGTAGCAGTTGCAATAGCCTTGTTTGGTTTAGATAGTGGTGCC
GCTTTAGCTACAGTAGTAGGGGTCTTGGAGGAAGTTCCAATAATGTTAAGCCTTGTATGGATAGCAAATAAGACAAGACA
CTTTTTCACAGCAAAATTTGAAACTGGAAGTGGGAGCAAAGCATGGGCCTTACTGAGGAATAGTTTACCTTACTACCCAT
ATTGTCCAAACCATGAAGATATACGTAAGGATACTTACAAGCAAATGAACCTTTATCCAGTGCTGTTTTTTCTTGGATAA

Upstream 100 bases:

>100_bases
GTTTTTCAATAGAGGATATATTGAGCTATATAGAACCTTACAACCATTGGTTTAGGAAAGATTTTTATTTGAAAGTTTTT
TCAATTCAAAAGGGATGAAA

Downstream 100 bases:

>100_bases
GAATATGAACGCTCCGCTAAGCATTGAAAAGTTCATTAATACAAAAGTTATGTATCCAAGGGTAGCATGATCAAAACTAA
CCATTTTTCATACCCTCCCA

Product: arsenical-resistance protein acr3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MGEKKGLSFFEKYLSLWVALCIVLGILIGKFMPSLPRTLSKLTIANVNMAIAVLIWAMIYPMMVKVDFSAIKRVHKGQML
KGLIVTWVTNWLIKPFSMFLISSFFIGTIFSMKLGLIDPSLAKEYIAGAILLGAAPCTAMVFVWSYLADGDPLYTLVQVA
TNDIIILFAFAPIVGFLMGLNKVPVPYDTLLLSVVLFVVIPLSAGYLSRRYILKTKGHKWFEQEFLPKLSTISIVGLLLT
LILLFSFQGEIILENPLHIALIAIPLTIQTYFIFAIAYGWAWIWKLPHKVAAPASFIGASNFFELAVAVAIALFGLDSGA
ALATVVGVLEEVPIMLSLVWIANKTRHFFTAKFETGSGSKAWALLRNSLPYYPYCPNHEDIRKDTYKQMNLYPVLFFLG

Sequences:

>Translated_399_residues
MGEKKGLSFFEKYLSLWVALCIVLGILIGKFMPSLPRTLSKLTIANVNMAIAVLIWAMIYPMMVKVDFSAIKRVHKGQML
KGLIVTWVTNWLIKPFSMFLISSFFIGTIFSMKLGLIDPSLAKEYIAGAILLGAAPCTAMVFVWSYLADGDPLYTLVQVA
TNDIIILFAFAPIVGFLMGLNKVPVPYDTLLLSVVLFVVIPLSAGYLSRRYILKTKGHKWFEQEFLPKLSTISIVGLLLT
LILLFSFQGEIILENPLHIALIAIPLTIQTYFIFAIAYGWAWIWKLPHKVAAPASFIGASNFFELAVAVAIALFGLDSGA
ALATVVGVLEEVPIMLSLVWIANKTRHFFTAKFETGSGSKAWALLRNSLPYYPYCPNHEDIRKDTYKQMNLYPVLFFLG
>Mature_398_residues
GEKKGLSFFEKYLSLWVALCIVLGILIGKFMPSLPRTLSKLTIANVNMAIAVLIWAMIYPMMVKVDFSAIKRVHKGQMLK
GLIVTWVTNWLIKPFSMFLISSFFIGTIFSMKLGLIDPSLAKEYIAGAILLGAAPCTAMVFVWSYLADGDPLYTLVQVAT
NDIIILFAFAPIVGFLMGLNKVPVPYDTLLLSVVLFVVIPLSAGYLSRRYILKTKGHKWFEQEFLPKLSTISIVGLLLTL
ILLFSFQGEIILENPLHIALIAIPLTIQTYFIFAIAYGWAWIWKLPHKVAAPASFIGASNFFELAVAVAIALFGLDSGAA
LATVVGVLEEVPIMLSLVWIANKTRHFFTAKFETGSGSKAWALLRNSLPYYPYCPNHEDIRKDTYKQMNLYPVLFFLG

Specific function: Unknown

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=341, Percent_Identity=26.9794721407625, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 44456; Mature: 44325

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEC
>Mature Secondary Structure 
GEKKGLSFFEKYLSLWVALCIVLGILIGKFMPSLPRTLSKLTIANVNMAIAVLIWAMIY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
PMMVKVDFSAIKRVHKGQMLKGLIVTWVTNWLIKPFSMFLISSFFIGTIFSMKLGLIDPS
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LAKEYIAGAILLGAAPCTAMVFVWSYLADGDPLYTLVQVATNDIIILFAFAPIVGFLMGL
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHCC
NKVPVPYDTLLLSVVLFVVIPLSAGYLSRRYILKTKGHKWFEQEFLPKLSTISIVGLLLT
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHEEEECCCCHHHHHHHCCHHHHHHHHHHHHH
LILLFSFQGEIILENPLHIALIAIPLTIQTYFIFAIAYGWAWIWKLPHKVAAPASFIGAS
HHHHHHCCCCEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHCCH
NFFELAVAVAIALFGLDSGAALATVVGVLEEVPIMLSLVWIANKTRHFFTAKFETGSGSK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCH
AWALLRNSLPYYPYCPNHEDIRKDTYKQMNLYPVLFFLG
HHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]