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The map label for this gene is nagD [H]

Identifier: 18976804

GI number: 18976804

Start: 440866

End: 441687

Strand: Direct

Name: nagD [H]

Synonym: PF0432

Alternate gene names: 18976804

Gene position: 440866-441687 (Clockwise)

Preceding gene: 18976803

Following gene: 18976805

Centisome position: 23.1

GC content: 40.02

Gene sequence:

>822_bases
ATGGAAATGAGGATAGTCTTTGACATGGATGGGGTATTGTACAGAGGGAACACTCCAATAGAAGGTGCAAGGGAAGTTAT
TGAGTTCCTAAAAGAGAAGGGAATAAAATTTGCATTTTTAACGAACAACTCGACAAAAACTCCTGAAATGTATAGGGAAA
GACTTCTGAAGATGGGCATAGATGTCCCCGCTGACTCAATAATAACTTCGGGACTTGCAACTAGGATTTATATGAAGAAA
CACTTTGAACCTGGGAAGATATTTGTCATAGGAGGAAGAGGGCTTGTAGAGGAGATGGAAAAGTTAGGCTGGGGAATTGT
GAGTGTTGAAGAAGCTAGAGAGGGCATTTGGAAGGAAGTGAAATATGTTGTCGTGGGCTTGGATCCGGAATTAACATATG
AAAAGCTGAAGTATGGAACTCTTGCAATAAGAAATGGAGCAGAGTTCATTGGGACTAATCCTGACAGAACATACCCAGGA
GAGGAAGGAATTTATCCTGGAGCTGGTTCTATAATAGCTGCTCTGGAGGCTGCAACAGATAAAAAGCCTCTAATAATTGG
AAAACCTAATGAGCCTATGTACGAAGTCCTAAGAGAGAAGTTGGGGGAAGGAGAAGTTTGGATGGTTGGGGATAGGCTTG
ATACTGACATTCTCTTTGCAAAGAAATTTGGAATGAAGGCAATTATGGTTTTAACTGGAGTTCACTCTCTTTCTGACATC
GAGAAAAGTGATATAAAGCCTGATCTAGTATTGCCAAGTATAAAAGAGCTATTGGAATATTTAAAAATACTACATGATGA
AGATAAAGAGGGCACCAAGTGA

Upstream 100 bases:

>100_bases
ATGAGAGCTTTGAGCTTGGAACAGTTAGTGAAAGACCTGGGATAATTGTCGAGAACTATGGTGTAAAGTTTATTTAAGTA
CAGCTCAACACCGCTTAGGG

Downstream 100 bases:

>100_bases
GGATAACTTTCAGGAATCTCTTAAAAACCTTGCATTTTCCTTTTGAAAACCTGTTGTCCTTCAATAAATCATTTTTCTGA
ATTTTCTTTGCTACTGGGTG

Product: putative sugar-catabolism phosphotransferase

Products: 4-nitrophenol; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MEMRIVFDMDGVLYRGNTPIEGAREVIEFLKEKGIKFAFLTNNSTKTPEMYRERLLKMGIDVPADSIITSGLATRIYMKK
HFEPGKIFVIGGRGLVEEMEKLGWGIVSVEEAREGIWKEVKYVVVGLDPELTYEKLKYGTLAIRNGAEFIGTNPDRTYPG
EEGIYPGAGSIIAALEAATDKKPLIIGKPNEPMYEVLREKLGEGEVWMVGDRLDTDILFAKKFGMKAIMVLTGVHSLSDI
EKSDIKPDLVLPSIKELLEYLKILHDEDKEGTK

Sequences:

>Translated_273_residues
MEMRIVFDMDGVLYRGNTPIEGAREVIEFLKEKGIKFAFLTNNSTKTPEMYRERLLKMGIDVPADSIITSGLATRIYMKK
HFEPGKIFVIGGRGLVEEMEKLGWGIVSVEEAREGIWKEVKYVVVGLDPELTYEKLKYGTLAIRNGAEFIGTNPDRTYPG
EEGIYPGAGSIIAALEAATDKKPLIIGKPNEPMYEVLREKLGEGEVWMVGDRLDTDILFAKKFGMKAIMVLTGVHSLSDI
EKSDIKPDLVLPSIKELLEYLKILHDEDKEGTK
>Mature_273_residues
MEMRIVFDMDGVLYRGNTPIEGAREVIEFLKEKGIKFAFLTNNSTKTPEMYRERLLKMGIDVPADSIITSGLATRIYMKK
HFEPGKIFVIGGRGLVEEMEKLGWGIVSVEEAREGIWKEVKYVVVGLDPELTYEKLKYGTLAIRNGAEFIGTNPDRTYPG
EEGIYPGAGSIIAALEAATDKKPLIIGKPNEPMYEVLREKLGEGEVWMVGDRLDTDILFAKKFGMKAIMVLTGVHSLSDI
EKSDIKPDLVLPSIKELLEYLKILHDEDKEGTK

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. NagD family [H]

Homologues:

Organism=Homo sapiens, GI108796653, Length=290, Percent_Identity=33.448275862069, Blast_Score=144, Evalue=6e-35,
Organism=Homo sapiens, GI10092677, Length=274, Percent_Identity=31.3868613138686, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI14149777, Length=262, Percent_Identity=29.0076335877863, Blast_Score=94, Evalue=9e-20,
Organism=Escherichia coli, GI1786890, Length=256, Percent_Identity=31.640625, Blast_Score=141, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI17562458, Length=283, Percent_Identity=29.6819787985866, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17560956, Length=293, Percent_Identity=30.3754266211604, Blast_Score=134, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17558880, Length=293, Percent_Identity=30.3754266211604, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI193210059, Length=262, Percent_Identity=32.4427480916031, Blast_Score=124, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI71984613, Length=265, Percent_Identity=33.2075471698113, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI86563050, Length=263, Percent_Identity=31.1787072243346, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17562356, Length=237, Percent_Identity=28.6919831223629, Blast_Score=87, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6319965, Length=236, Percent_Identity=33.0508474576271, Blast_Score=139, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24666141, Length=278, Percent_Identity=30.2158273381295, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24656326, Length=281, Percent_Identity=30.2491103202847, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24656330, Length=283, Percent_Identity=30.3886925795053, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24666137, Length=289, Percent_Identity=29.757785467128, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI22026920, Length=286, Percent_Identity=26.2237762237762, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI19920940, Length=264, Percent_Identity=26.8939393939394, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI18859765, Length=246, Percent_Identity=26.4227642276423, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641437, Length=242, Percent_Identity=28.099173553719, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR006354
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.3.41

Molecular weight: Translated: 30618; Mature: 30618

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMRIVFDMDGVLYRGNTPIEGAREVIEFLKEKGIKFAFLTNNSTKTPEMYRERLLKMGI
CCEEEEEECCCEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCC
DVPADSIITSGLATRIYMKKHFEPGKIFVIGGRGLVEEMEKLGWGIVSVEEAREGIWKEV
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCEEEHHHHHHHHHHEE
KYVVVGLDPELTYEKLKYGTLAIRNGAEFIGTNPDRTYPGEEGIYPGAGSIIAALEAATD
EEEEEECCCCCHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCC
KKPLIIGKPNEPMYEVLREKLGEGEVWMVGDRLDTDILFAKKFGMKAIMVLTGVHSLSDI
CCCEEEECCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHH
EKSDIKPDLVLPSIKELLEYLKILHDEDKEGTK
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MEMRIVFDMDGVLYRGNTPIEGAREVIEFLKEKGIKFAFLTNNSTKTPEMYRERLLKMGI
CCEEEEEECCCEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCC
DVPADSIITSGLATRIYMKKHFEPGKIFVIGGRGLVEEMEKLGWGIVSVEEAREGIWKEV
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCEEEHHHHHHHHHHEE
KYVVVGLDPELTYEKLKYGTLAIRNGAEFIGTNPDRTYPGEEGIYPGAGSIIAALEAATD
EEEEEECCCCCHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCC
KKPLIIGKPNEPMYEVLREKLGEGEVWMVGDRLDTDILFAKKFGMKAIMVLTGVHSLSDI
CCCEEEECCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHH
EKSDIKPDLVLPSIKELLEYLKILHDEDKEGTK
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-nitrophenyl phosphate; H2O

Specific reaction: 4-nitrophenyl phosphate + H2O = 4-nitrophenol + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA