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The map label for this gene is pfdB [H]

Identifier: 18976754

GI number: 18976754

Start: 393402

End: 393923

Strand: Direct

Name: pfdB [H]

Synonym: PF0382

Alternate gene names: 18976754

Gene position: 393402-393923 (Clockwise)

Preceding gene: 18976753

Following gene: 18976755

Centisome position: 20.62

GC content: 43.3

Gene sequence:

>522_bases
ATGAATCCCAGGGTGTGCCAAGTGGATTTAGGAGCTTTGTTTACAAGGGAGAAGGGGCCTACATTTGGAGGAGTCCCGAG
ACAGTTAACGTTGAGTTTGGAAAACTTCTATCCCAGGGTGAGGAAGGTTCTTAAATATTCCTCTGAAGTTAGAGCTGAGG
TGGTGAAGATGCAAAACATTCCACCCCAAGTCCAGGCAATGCTTGGGCAATTAGAGAGCTACCAGCAGCAACTCCAACTC
GTTATTCAGCAGAAGCAGAAGGTTCAAGCTGATTTAAATGAAGCTAAAAAGGCCCTTGAGGAAATTGAAAAGCTCACTGA
TGATGCTGTAATTTACAAGACCGTTGGCACGTTGATAGTTAAAACGACAAAAGAAAAAGCTTTACAGGAACTTAAGGAGA
AAGTAGAAACTCTTGAAGTTAGGCTTAATGCGCTAAACAGGCAAGAGCAGAAGATAAATGAAAAGATAAAGGAGCTCACT
CAAAAGATTCAGGCAGCCCTAAGACCTCCAACCGCTGGATGA

Upstream 100 bases:

>100_bases
GTCGCCATAGTTGGAACTAAGTATGCCCTAGATTTCGTTTTGTCAACCCCTGGGCCTACTTTGGTACTCTACAACGATCC
AGAGGTTCAGTCAATGATAT

Downstream 100 bases:

>100_bases
CTTCTTTTATTATTTTTGTTTTCTCTGGTGGTTGATATGAAAAAAGTTATTCACATCGGACTTCCAGAGCTAAGCGAGGA
AGAATTGATTAGGGTTGGAG

Product: prefoldin

Products: NA

Alternate protein names: GimC subunit beta [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MNPRVCQVDLGALFTREKGPTFGGVPRQLTLSLENFYPRVRKVLKYSSEVRAEVVKMQNIPPQVQAMLGQLESYQQQLQL
VIQQKQKVQADLNEAKKALEEIEKLTDDAVIYKTVGTLIVKTTKEKALQELKEKVETLEVRLNALNRQEQKINEKIKELT
QKIQAALRPPTAG

Sequences:

>Translated_173_residues
MNPRVCQVDLGALFTREKGPTFGGVPRQLTLSLENFYPRVRKVLKYSSEVRAEVVKMQNIPPQVQAMLGQLESYQQQLQL
VIQQKQKVQADLNEAKKALEEIEKLTDDAVIYKTVGTLIVKTTKEKALQELKEKVETLEVRLNALNRQEQKINEKIKELT
QKIQAALRPPTAG
>Mature_173_residues
MNPRVCQVDLGALFTREKGPTFGGVPRQLTLSLENFYPRVRKVLKYSSEVRAEVVKMQNIPPQVQAMLGQLESYQQQLQL
VIQQKQKVQADLNEAKKALEEIEKLTDDAVIYKTVGTLIVKTTKEKALQELKEKVETLEVRLNALNRQEQKINEKIKELT
QKIQAALRPPTAG

Specific function: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding [H]

COG id: COG1382

COG function: function code O; Prefoldin, chaperonin cofactor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prefoldin subunit beta family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012713
- InterPro:   IPR002777
- InterPro:   IPR009053 [H]

Pfam domain/function: PF01920 Prefoldin_2 [H]

EC number: NA

Molecular weight: Translated: 19696; Mature: 19696

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPRVCQVDLGALFTREKGPTFGGVPRQLTLSLENFYPRVRKVLKYSSEVRAEVVKMQNI
CCCCEEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PPQVQAMLGQLESYQQQLQLVIQQKQKVQADLNEAKKALEEIEKLTDDAVIYKTVGTLIV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KTTKEKALQELKEKVETLEVRLNALNRQEQKINEKIKELTQKIQAALRPPTAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNPRVCQVDLGALFTREKGPTFGGVPRQLTLSLENFYPRVRKVLKYSSEVRAEVVKMQNI
CCCCEEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PPQVQAMLGQLESYQQQLQLVIQQKQKVQADLNEAKKALEEIEKLTDDAVIYKTVGTLIV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KTTKEKALQELKEKVETLEVRLNALNRQEQKINEKIKELTQKIQAALRPPTAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]