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The map label for this gene is ychF [C]

Identifier: 18976746

GI number: 18976746

Start: 388629

End: 389822

Strand: Direct

Name: ychF [C]

Synonym: PF0374

Alternate gene names: 18976746

Gene position: 388629-389822 (Clockwise)

Preceding gene: 18976745

Following gene: 33359476

Centisome position: 20.37

GC content: 42.8

Gene sequence:

>1194_bases
ATGGAAATTGGAGTGGTAGGAAAACCAAATGTAGGGAAATCAACATTCTTCTCAGCCGCCACCTTGGTTGATGTGGAGAT
AGCAAATTACCCCTTTACCACGATAAACGCAAACGTTGGAGTTACCTACGCGATAACCGAACATCCATGTAAGGAGCTTG
GCTGCACGCCAAATCCTCAAAACTATGAGTATAGAGAGGGATTAGCTTTAATTCCAGTGAAAATGATTGACGTCGCTGGT
CTAGTCCCAGGAGCTCACGAAGGGAGGGGGCTTGGCAACAAGTTCTTAGATGACTTAAGAATGGCCTCTGCCCTAATTCA
CGTTATAGATGCCACGGGGAAAACAGATGAAGAGGGCAGGCCCACAGATTTTCATGATCCAGTGGAAGACATAGAATTCC
TAGAAAGGGAGATTGATTACTGGATCTATGGAATACTAAAGAAGGGGTGGGAGAAGTTTGCAAAGAGAATAAAGCTTCAG
AAAATGAAAATTGAAACCGCGATAGCGGAGCACTTAAGCGGAATTGGAGTTACTGAGAATGATGTGTGGGAGGCTATGCA
TAGGCTTGGCCTTCCAGATGATCCTACCGCTTGGAGTGACGAGGACTTGCTGAGCTTTGCCTCGGAGATTAGGAAGATAA
ACAAGCCAATGATAATAGCGGCAAATAAGGCAGATGCAGCTAGTGATGAGGATATAAAGAGATTAAAGAGAGAAGGAGAA
AAGAGAGGATACATTGTAGTCCCCACCTCAGCCGCCGCTGAACTAACCCTTAGAAAAGCGGCAAAGGCTGGGTTTATTGA
ATACATCCCAGGATCTAGTGATTTTAAAATACTCAAAGAAATGAGTGAAAAGCAGAAAAAGGCCTTAATGTTAATCAAGG
AGAGAGTTTTAGATAGGTTTGGCTCAACTGGAGTTCAAGAGGTAATAAATAAGGCAGTATTTGAGCTCCTAAAGCTGATT
CCAGTGTATCCGGTGCAGGATGAGAATAAGCTAACGGATCAATTTGGAAATGTCCTTCCACATGTGTTTCTAATGAAAAA
GGGCTCAACTCCCAGGGATCTAGCATTTAAAGTTCACACCGATCTTGGTAAGGGATTCCTCTATGCAATAAACGCTAAAA
CAAAAAGAAGAGTTGGAGAAGACTACGAGCTTCAATTCAACGATATAATAAAGATTGTTGCAGTTACCAAGTGA

Upstream 100 bases:

>100_bases
AATAGTTGGAGTCTCCATAGGGGTTGTCATCAGGAAGTGTCCAGTGTTCTGAGGTAGATTTATATTCTCCCTTCCCAACT
TTTATCCTTGGGATGAAAAG

Downstream 100 bases:

>100_bases
CCTCTTTTTTTCTTCACTTCTTAAGCTTGAAGCTCATTGCTTGTTTTTGTTGGATCTCTTGTGCCTTCTTTGCTAGCTCA
GCTGCTCTCTTCTGAAGCTC

Product: translation-associated GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MEIGVVGKPNVGKSTFFSAATLVDVEIANYPFTTINANVGVTYAITEHPCKELGCTPNPQNYEYREGLALIPVKMIDVAG
LVPGAHEGRGLGNKFLDDLRMASALIHVIDATGKTDEEGRPTDFHDPVEDIEFLEREIDYWIYGILKKGWEKFAKRIKLQ
KMKIETAIAEHLSGIGVTENDVWEAMHRLGLPDDPTAWSDEDLLSFASEIRKINKPMIIAANKADAASDEDIKRLKREGE
KRGYIVVPTSAAAELTLRKAAKAGFIEYIPGSSDFKILKEMSEKQKKALMLIKERVLDRFGSTGVQEVINKAVFELLKLI
PVYPVQDENKLTDQFGNVLPHVFLMKKGSTPRDLAFKVHTDLGKGFLYAINAKTKRRVGEDYELQFNDIIKIVAVTK

Sequences:

>Translated_397_residues
MEIGVVGKPNVGKSTFFSAATLVDVEIANYPFTTINANVGVTYAITEHPCKELGCTPNPQNYEYREGLALIPVKMIDVAG
LVPGAHEGRGLGNKFLDDLRMASALIHVIDATGKTDEEGRPTDFHDPVEDIEFLEREIDYWIYGILKKGWEKFAKRIKLQ
KMKIETAIAEHLSGIGVTENDVWEAMHRLGLPDDPTAWSDEDLLSFASEIRKINKPMIIAANKADAASDEDIKRLKREGE
KRGYIVVPTSAAAELTLRKAAKAGFIEYIPGSSDFKILKEMSEKQKKALMLIKERVLDRFGSTGVQEVINKAVFELLKLI
PVYPVQDENKLTDQFGNVLPHVFLMKKGSTPRDLAFKVHTDLGKGFLYAINAKTKRRVGEDYELQFNDIIKIVAVTK
>Mature_397_residues
MEIGVVGKPNVGKSTFFSAATLVDVEIANYPFTTINANVGVTYAITEHPCKELGCTPNPQNYEYREGLALIPVKMIDVAG
LVPGAHEGRGLGNKFLDDLRMASALIHVIDATGKTDEEGRPTDFHDPVEDIEFLEREIDYWIYGILKKGWEKFAKRIKLQ
KMKIETAIAEHLSGIGVTENDVWEAMHRLGLPDDPTAWSDEDLLSFASEIRKINKPMIIAANKADAASDEDIKRLKREGE
KRGYIVVPTSAAAELTLRKAAKAGFIEYIPGSSDFKILKEMSEKQKKALMLIKERVLDRFGSTGVQEVINKAVFELLKLI
PVYPVQDENKLTDQFGNVLPHVFLMKKGSTPRDLAFKVHTDLGKGFLYAINAKTKRRVGEDYELQFNDIIKIVAVTK

Specific function: Unknown

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=384, Percent_Identity=25.5208333333333, Blast_Score=92, Evalue=6e-19,
Organism=Escherichia coli, GI1787454, Length=379, Percent_Identity=26.6490765171504, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1789574, Length=201, Percent_Identity=30.3482587064677, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17552324, Length=142, Percent_Identity=31.6901408450704, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321649, Length=364, Percent_Identity=39.8351648351648, Blast_Score=215, Evalue=9e-57,
Organism=Saccharomyces cerevisiae, GI6321773, Length=186, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24640873, Length=427, Percent_Identity=24.5901639344262, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24640877, Length=427, Percent_Identity=24.5901639344262, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24640875, Length=427, Percent_Identity=24.5901639344262, Blast_Score=78, Evalue=9e-15,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR006073
- InterPro:   IPR013646
- InterPro:   IPR002917
- InterPro:   IPR004095
- InterPro:   IPR012676 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF08438 MMR_HSR1_C; PF02824 TGS [H]

EC number: NA

Molecular weight: Translated: 44338; Mature: 44338

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIGVVGKPNVGKSTFFSAATLVDVEIANYPFTTINANVGVTYAITEHPCKELGCTPNPQ
CCCCCCCCCCCCCHHHHHHHEEEEEEECCCCCEEEECCCCEEEEECCCCHHHCCCCCCCC
NYEYREGLALIPVKMIDVAGLVPGAHEGRGLGNKFLDDLRMASALIHVIDATGKTDEEGR
CCHHHCCEEEECHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PTDFHDPVEDIEFLEREIDYWIYGILKKGWEKFAKRIKLQKMKIETAIAEHLSGIGVTEN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DVWEAMHRLGLPDDPTAWSDEDLLSFASEIRKINKPMIIAANKADAASDEDIKRLKREGE
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCC
KRGYIVVPTSAAAELTLRKAAKAGFIEYIPGSSDFKILKEMSEKQKKALMLIKERVLDRF
CCCEEEEECCHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSTGVQEVINKAVFELLKLIPVYPVQDENKLTDQFGNVLPHVFLMKKGSTPRDLAFKVHT
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHEEEEEECCCCCCCEEEEEEC
DLGKGFLYAINAKTKRRVGEDYELQFNDIIKIVAVTK
CCCCCEEEEECCHHHHHCCCCCEEEHHHEEEEEEECC
>Mature Secondary Structure
MEIGVVGKPNVGKSTFFSAATLVDVEIANYPFTTINANVGVTYAITEHPCKELGCTPNPQ
CCCCCCCCCCCCCHHHHHHHEEEEEEECCCCCEEEECCCCEEEEECCCCHHHCCCCCCCC
NYEYREGLALIPVKMIDVAGLVPGAHEGRGLGNKFLDDLRMASALIHVIDATGKTDEEGR
CCHHHCCEEEECHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PTDFHDPVEDIEFLEREIDYWIYGILKKGWEKFAKRIKLQKMKIETAIAEHLSGIGVTEN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DVWEAMHRLGLPDDPTAWSDEDLLSFASEIRKINKPMIIAANKADAASDEDIKRLKREGE
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCC
KRGYIVVPTSAAAELTLRKAAKAGFIEYIPGSSDFKILKEMSEKQKKALMLIKERVLDRF
CCCEEEEECCHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSTGVQEVINKAVFELLKLIPVYPVQDENKLTDQFGNVLPHVFLMKKGSTPRDLAFKVHT
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHEEEEEECCCCCCCEEEEEEC
DLGKGFLYAINAKTKRRVGEDYELQFNDIIKIVAVTK
CCCCCEEEEECCHHHHHCCCCCEEEHHHEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]