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The map label for this gene is lrp [C]

Identifier: 18976622

GI number: 18976622

Start: 258208

End: 258687

Strand: Direct

Name: lrp [C]

Synonym: PF0250

Alternate gene names: 18976622

Gene position: 258208-258687 (Clockwise)

Preceding gene: 18976621

Following gene: 18976623

Centisome position: 13.53

GC content: 41.46

Gene sequence:

>480_bases
GTGTCAAACATAATCTTGGTGGTTAAAATGGCAGAGCTCTTAGACAGGACTGATAAAATGTTGCTCGAAGAGCTCAAGAA
AAATGCGAGAGAAAACATAGCAGCCCTAAGCAAAAAGCTTGGAATTCCCAGGACAACCGTCCACTATAGGATAAAGAGGC
TCCTAGAGGAGGGTATAATTGAGAAGTTCACGATAAAACCAAACTACAAGAAGCTAAACCTTGGAACAACGGCCTTTGTA
TTGATTAGATATGACCCTGATTCTGGCCTAACCCAAAAGGAGGTTGCCGAACAAATAGCTAAAATACCGGGCGTTTATGA
AGTTCACATAGTTGCGGGGGAATGGGACATTCTCCTCAAAGTTAGGGCCGCAAATGCAGAAGAAGTTGGTAAAATTGTGA
TAGAGAAGTTAAGGGAGATTAAGGGTGTGGGGCAAACTGTAACAATGGTGTCTTTTGTTACCATTAAAGAAGAGATTTAA

Upstream 100 bases:

>100_bases
GCCGAAATGTCAACAGAAGAAAAAAATTCTGTATCTCATAGGGGAAAGGCTTTAAAGGAATTCTATAGATGGATGAAAGA
AAACCTTAAAAAATGAATAT

Downstream 100 bases:

>100_bases
AGTTGGGGTCTTCCTCATGTGAACTTTTATGAGTTCACGTGAGAATTCATTCCCCGATTTACTGTGAGTGCCCGGACTTA
GACCGTCCCACCCATTTCTC

Product: Lrp family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MSNIILVVKMAELLDRTDKMLLEELKKNARENIAALSKKLGIPRTTVHYRIKRLLEEGIIEKFTIKPNYKKLNLGTTAFV
LIRYDPDSGLTQKEVAEQIAKIPGVYEVHIVAGEWDILLKVRAANAEEVGKIVIEKLREIKGVGQTVTMVSFVTIKEEI

Sequences:

>Translated_159_residues
MSNIILVVKMAELLDRTDKMLLEELKKNARENIAALSKKLGIPRTTVHYRIKRLLEEGIIEKFTIKPNYKKLNLGTTAFV
LIRYDPDSGLTQKEVAEQIAKIPGVYEVHIVAGEWDILLKVRAANAEEVGKIVIEKLREIKGVGQTVTMVSFVTIKEEI
>Mature_158_residues
SNIILVVKMAELLDRTDKMLLEELKKNARENIAALSKKLGIPRTTVHYRIKRLLEEGIIEKFTIKPNYKKLNLGTTAFVL
IRYDPDSGLTQKEVAEQIAKIPGVYEVHIVAGEWDILLKVRAANAEEVGKIVIEKLREIKGVGQTVTMVSFVTIKEEI

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=144, Percent_Identity=30.5555555555556, Blast_Score=71, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR002197
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF02954 HTH_8 [H]

EC number: NA

Molecular weight: Translated: 17985; Mature: 17853

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNIILVVKMAELLDRTDKMLLEELKKNARENIAALSKKLGIPRTTVHYRIKRLLEEGII
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCH
EKFTIKPNYKKLNLGTTAFVLIRYDPDSGLTQKEVAEQIAKIPGVYEVHIVAGEWDILLK
HEEEECCCCEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEEECCEEEEEE
VRAANAEEVGKIVIEKLREIKGVGQTVTMVSFVTIKEEI
EECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHEEEECCC
>Mature Secondary Structure 
SNIILVVKMAELLDRTDKMLLEELKKNARENIAALSKKLGIPRTTVHYRIKRLLEEGII
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCH
EKFTIKPNYKKLNLGTTAFVLIRYDPDSGLTQKEVAEQIAKIPGVYEVHIVAGEWDILLK
HEEEECCCCEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEEECCEEEEEE
VRAANAEEVGKIVIEKLREIKGVGQTVTMVSFVTIKEEI
EECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA