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The map label for this gene is purQ [H]

Identifier: 18976570

GI number: 18976570

Start: 209565

End: 210248

Strand: Direct

Name: purQ [H]

Synonym: PF0198

Alternate gene names: 18976570

Gene position: 209565-210248 (Clockwise)

Preceding gene: 18976569

Following gene: 18976571

Centisome position: 10.98

GC content: 42.25

Gene sequence:

>684_bases
ATGGTGAGAATTATGGTAAAATTTGCCGTAGTGGTGTTTCCTGGGACTAATTGCGATTTTGAAACTGTCGAGGCAATAAA
AAGAGCTGGTGGGAAAGCTGAGAGAGTTTGGTATAAAGATAGCATAAAAGATTATGATGGAGTTGTTATTCCGGGAGGAT
TTAGTTACGCTGATTATTTGAGAGCTGGAGCAATAGCTGCTAGGCAAAGGATAATGGAGGAAATAAGAGAGCTCGCCGAA
GAAGGGAGACCTATACTCGGAATATGCAATGGTTTTCAGATTCTAACTGAGGCAGGCCTTCTTCCTGGGGCTCTTAGACC
AAATAAAATACCAAGGTTTTTATGCAAGTGGGTCCACTTGAAAGTTGTTGATGTTAGGACTCCTTTTACGTACCTTTACG
AGGAAGGAGAAGTAGTGAGGATGCCAATAGCACATGCAGAGGGCAATTACTACATCGATGATCCCTCAAAAGTTAGGATA
GTGTTTCAGTACAGTGATGAGAAGGGAAGTATTACAGAGGAAGCTAATCCCAACGGTTCTGTGTTGAATATAGCCGGAGT
TGCAAATATGGAGGGAAATATTCTTGGAATGATGCCACATCCAGAAAGAGCTAGTCACTACTTCCTGGGAAGTGAAGATG
GGTTAAAAGTGTTTAAGGGCATGGTTGAGTGGGTTAGGAGTTGA

Upstream 100 bases:

>100_bases
TCATTCTTGAGAGTGACAATCCAGAAAAAGACGTTGAGGAGATGTGTAGGAGGTTGTTAGCCAACCCTTTAATTCACACT
TGGGAATACACCATTGAAGA

Downstream 100 bases:

>100_bases
TATTTTTCTCGCCCTGAAGGAGGCTTTTAGATTTTAACATTTTTAAGTCAAAACAAATCTTAAAAATTTAAAATTTTTAC
ATTTTTCTGACAATAAGGAG

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MVRIMVKFAVVVFPGTNCDFETVEAIKRAGGKAERVWYKDSIKDYDGVVIPGGFSYADYLRAGAIAARQRIMEEIRELAE
EGRPILGICNGFQILTEAGLLPGALRPNKIPRFLCKWVHLKVVDVRTPFTYLYEEGEVVRMPIAHAEGNYYIDDPSKVRI
VFQYSDEKGSITEEANPNGSVLNIAGVANMEGNILGMMPHPERASHYFLGSEDGLKVFKGMVEWVRS

Sequences:

>Translated_227_residues
MVRIMVKFAVVVFPGTNCDFETVEAIKRAGGKAERVWYKDSIKDYDGVVIPGGFSYADYLRAGAIAARQRIMEEIRELAE
EGRPILGICNGFQILTEAGLLPGALRPNKIPRFLCKWVHLKVVDVRTPFTYLYEEGEVVRMPIAHAEGNYYIDDPSKVRI
VFQYSDEKGSITEEANPNGSVLNIAGVANMEGNILGMMPHPERASHYFLGSEDGLKVFKGMVEWVRS
>Mature_227_residues
MVRIMVKFAVVVFPGTNCDFETVEAIKRAGGKAERVWYKDSIKDYDGVVIPGGFSYADYLRAGAIAARQRIMEEIRELAE
EGRPILGICNGFQILTEAGLLPGALRPNKIPRFLCKWVHLKVVDVRTPFTYLYEEGEVVRMPIAHAEGNYYIDDPSKVRI
VFQYSDEKGSITEEANPNGSVLNIAGVANMEGNILGMMPHPERASHYFLGSEDGLKVFKGMVEWVRS

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=244, Percent_Identity=29.5081967213115, Blast_Score=74, Evalue=7e-14,
Organism=Escherichia coli, GI48994899, Length=226, Percent_Identity=33.1858407079646, Blast_Score=83, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24582111, Length=235, Percent_Identity=32.3404255319149, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24582109, Length=235, Percent_Identity=32.3404255319149, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17137292, Length=235, Percent_Identity=32.3404255319149, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 25393; Mature: 25393

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRIMVKFAVVVFPGTNCDFETVEAIKRAGGKAERVWYKDSIKDYDGVVIPGGFSYADYL
CEEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCEEECCCCCHHHHH
RAGAIAARQRIMEEIRELAEEGRPILGICNGFQILTEAGLLPGALRPNKIPRFLCKWVHL
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCCCCCCCCCHHHHHHHHHEE
KVVDVRTPFTYLYEEGEVVRMPIAHAEGNYYIDDPSKVRIVFQYSDEKGSITEEANPNGS
EEEEECCCEEEEECCCCEEEEEEEECCCCEEECCCCEEEEEEEEECCCCCCCCCCCCCCC
VLNIAGVANMEGNILGMMPHPERASHYFLGSEDGLKVFKGMVEWVRS
EEEEEEEECCCCCEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MVRIMVKFAVVVFPGTNCDFETVEAIKRAGGKAERVWYKDSIKDYDGVVIPGGFSYADYL
CEEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCEEECCCCCHHHHH
RAGAIAARQRIMEEIRELAEEGRPILGICNGFQILTEAGLLPGALRPNKIPRFLCKWVHL
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCCCCCCCCCHHHHHHHHHEE
KVVDVRTPFTYLYEEGEVVRMPIAHAEGNYYIDDPSKVRIVFQYSDEKGSITEEANPNGS
EEEEECCCEEEEECCCCEEEEEEEECCCCEEECCCCEEEEEEEEECCCCCCCCCCCCCCC
VLNIAGVANMEGNILGMMPHPERASHYFLGSEDGLKVFKGMVEWVRS
EEEEEEEECCCCCEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA