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The map label for this gene is atpI [H]

Identifier: 18976549

GI number: 18976549

Start: 186107

End: 188098

Strand: Direct

Name: atpI [H]

Synonym: PF0177

Alternate gene names: 18976549

Gene position: 186107-188098 (Clockwise)

Preceding gene: 33359456

Following gene: 18976550

Centisome position: 9.75

GC content: 39.16

Gene sequence:

>1992_bases
ATGTTCAAACCAGAAGAGATGGTTAAGATTGAGCTAATTTCTTTAGCGAGATATAGAGATATTATAATGACTTATCTCCA
TGAAAGGGGAGTCGTTCAGCTTGAAGAAGTTCCAATAGAGGATATCCAACACGATGCTCCAAACGAGTATTATAGGAAGG
CCACATCTTACAGCATTACAATGGGAAGGTTAGTAGATACCCTGAAAGGATTTCTTCCTCCCAGAAAAACCAGTATTAAG
GAGTTTATTTTTCCAAAAGAGAGAGAAAAGAGAGTGTATACCTATAGAGGGATAGAAGATCTAGTAAAGGATGTGGAGAA
ATTTCTTAGTGAAGTTGAGCCTAAAATTAGAGAAGTTGAAACTCAGCTAACAGCGATTAATAATAGAATTGCCAATATTA
GGGAAATTATTAACACCCTTGAGTTACTCTCTTCATTGAACATCGAGATTGAATATCTAATTCCTGGAAGTTTCTTGGCT
ATTGAAGTTGGTAAAATTGAGAGGGAGAGAGTTGAAAAGCTTATTGGCGAGTTAAAAAATGAGCTTGGTGACAAAGTTTT
TATCCTGAGAAGAGATCTTGGGACAATTTCTCTATTGGTTGTTGTTACCCTGAAAGAGTTCCAGGGTAAGCTTACTTCAA
TTTTAGCCAAATATGGGTTTGAAAAGGTTGAAATTCCCAGGGAGAGAGGGCATCCTAGAGAGTTAATTCCAAAATATAAT
GAGCTTCTTAAGGAAGAAATGAAAAAATTGGAAGAGATAAGGAAAAAGGGAAGAGAGTTTGCAGAAAAATACTACGAAGA
CTTAGTCTTCTACAAGGAACTTATGGATAATGAGAGGGATAAGGCCAACTATTTGAGTTATCTAGCAAGAACTGAACTTA
CAGTCGCCTTAGTAGGATGGCTCCCAAAGAAGAATGTTGAAGAGGTTGTTGAAGGAATAAAGAATCTAACGGGGGGAAAA
GTCTACATTAACATTAGAGAACCCGAGCCTAATGAGATAGAGGAAGTTCCTGTCAAGCTAAAGAATCCCGAATTCATAAG
CCAGTTTGAAATGTTAACCGAGATGTATGGTGTTCCTAAATATAACGAACTTGATCCTACCCCAATATTGGCATTTACGT
ACTCGTTTTTCTTTGGGTTCATGCTCACTGACTTTATGTATGGTTTGCTCCTGGGAATAGTTTCGGCATTGTTAGTAAAG
GGACATTCAAAAATGAAGGATGGAACTTGGAAGTTTGCTAAGATAATGTTGTGGTCTTCGGTCTTCACAATGCTCTTAGG
TGCCCTTTTTGGAAGCTACTTTGGCAATGCTCTTGATATGGCGGGATTCAAAGTTCCCAGGATAATGGATGCTATGGAGG
AGGCATTGACAGTCCTAATCATAGCTTTGGCAATAGGACTTGGGCATTTATTCACAGGTTATGTCCTTGGATTTATCGTG
AAGTGGAAAAATGGAGACAAAGTTGGCGCAATCCTTGACCAGTTATCTTGGATACTAATAATCCTCGGCGTTACTCTGTT
CGCCATATCTTCGAGAATTGATTTACCAAAATTAGCATGGATGTCAGTCTTTGGTGCGGGAGCAGTACTATTCATAATAG
GCGAATTCAAAAACAACGGACTTATGGCCTTACTTTTAGTGATTTCAGATTTCTTCGGATTTGTGGGGAATTGGCTGAGC
TACGCAAGATTAATGGCCCTGGCATTAGCAACTGCTGGAATAGCTCTTGTGATAAACATAATGGTTCAAATGATATGGGG
ATTCAAGATAGGGCCTGTTCCCCTGGGAATTATTGTTGGAGCAATAGTCTTTATTGGAGGACACATATTCTCCACTGCGA
TAAACGCTCTTGGGGCATTTGTTCACGCTCTCCGTTTGCACTATGTTGAGTTTTTTGGAACATTTTACTCAGGTGAAGGC
CGTAGGTTTGAACCCTTTGCTGCTAGAAGAGAAATTTCTGAGTTGAAGATAGAAAAGCCTGGAGGTGAATGA

Upstream 100 bases:

>100_bases
GAGGAAGGAGAAAAAGAAATTGAAGAATTAAAGGTAAAAGCTGAGGAAAAGTTTGAAACGGCTGTTTCTGAATGTTTGAG
AATAATAAGAGGGGTGTAGT

Downstream 100 bases:

>100_bases
AATGGATCCTATAGTTTATGTTGCTTTAGGAATGGCACTTGGAGCAGGAATTGCAGGAGCTGCCTCTTCATTTGGAGTTG
GAATTGCAGGAGCAGCTGCA

Product: V-type ATP synthase subunit I

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit I [H]

Number of amino acids: Translated: 663; Mature: 663

Protein sequence:

>663_residues
MFKPEEMVKIELISLARYRDIIMTYLHERGVVQLEEVPIEDIQHDAPNEYYRKATSYSITMGRLVDTLKGFLPPRKTSIK
EFIFPKEREKRVYTYRGIEDLVKDVEKFLSEVEPKIREVETQLTAINNRIANIREIINTLELLSSLNIEIEYLIPGSFLA
IEVGKIERERVEKLIGELKNELGDKVFILRRDLGTISLLVVVTLKEFQGKLTSILAKYGFEKVEIPRERGHPRELIPKYN
ELLKEEMKKLEEIRKKGREFAEKYYEDLVFYKELMDNERDKANYLSYLARTELTVALVGWLPKKNVEEVVEGIKNLTGGK
VYINIREPEPNEIEEVPVKLKNPEFISQFEMLTEMYGVPKYNELDPTPILAFTYSFFFGFMLTDFMYGLLLGIVSALLVK
GHSKMKDGTWKFAKIMLWSSVFTMLLGALFGSYFGNALDMAGFKVPRIMDAMEEALTVLIIALAIGLGHLFTGYVLGFIV
KWKNGDKVGAILDQLSWILIILGVTLFAISSRIDLPKLAWMSVFGAGAVLFIIGEFKNNGLMALLLVISDFFGFVGNWLS
YARLMALALATAGIALVINIMVQMIWGFKIGPVPLGIIVGAIVFIGGHIFSTAINALGAFVHALRLHYVEFFGTFYSGEG
RRFEPFAARREISELKIEKPGGE

Sequences:

>Translated_663_residues
MFKPEEMVKIELISLARYRDIIMTYLHERGVVQLEEVPIEDIQHDAPNEYYRKATSYSITMGRLVDTLKGFLPPRKTSIK
EFIFPKEREKRVYTYRGIEDLVKDVEKFLSEVEPKIREVETQLTAINNRIANIREIINTLELLSSLNIEIEYLIPGSFLA
IEVGKIERERVEKLIGELKNELGDKVFILRRDLGTISLLVVVTLKEFQGKLTSILAKYGFEKVEIPRERGHPRELIPKYN
ELLKEEMKKLEEIRKKGREFAEKYYEDLVFYKELMDNERDKANYLSYLARTELTVALVGWLPKKNVEEVVEGIKNLTGGK
VYINIREPEPNEIEEVPVKLKNPEFISQFEMLTEMYGVPKYNELDPTPILAFTYSFFFGFMLTDFMYGLLLGIVSALLVK
GHSKMKDGTWKFAKIMLWSSVFTMLLGALFGSYFGNALDMAGFKVPRIMDAMEEALTVLIIALAIGLGHLFTGYVLGFIV
KWKNGDKVGAILDQLSWILIILGVTLFAISSRIDLPKLAWMSVFGAGAVLFIIGEFKNNGLMALLLVISDFFGFVGNWLS
YARLMALALATAGIALVINIMVQMIWGFKIGPVPLGIIVGAIVFIGGHIFSTAINALGAFVHALRLHYVEFFGTFYSGEG
RRFEPFAARREISELKIEKPGGE
>Mature_663_residues
MFKPEEMVKIELISLARYRDIIMTYLHERGVVQLEEVPIEDIQHDAPNEYYRKATSYSITMGRLVDTLKGFLPPRKTSIK
EFIFPKEREKRVYTYRGIEDLVKDVEKFLSEVEPKIREVETQLTAINNRIANIREIINTLELLSSLNIEIEYLIPGSFLA
IEVGKIERERVEKLIGELKNELGDKVFILRRDLGTISLLVVVTLKEFQGKLTSILAKYGFEKVEIPRERGHPRELIPKYN
ELLKEEMKKLEEIRKKGREFAEKYYEDLVFYKELMDNERDKANYLSYLARTELTVALVGWLPKKNVEEVVEGIKNLTGGK
VYINIREPEPNEIEEVPVKLKNPEFISQFEMLTEMYGVPKYNELDPTPILAFTYSFFFGFMLTDFMYGLLLGIVSALLVK
GHSKMKDGTWKFAKIMLWSSVFTMLLGALFGSYFGNALDMAGFKVPRIMDAMEEALTVLIIALAIGLGHLFTGYVLGFIV
KWKNGDKVGAILDQLSWILIILGVTLFAISSRIDLPKLAWMSVFGAGAVLFIIGEFKNNGLMALLLVISDFFGFVGNWLS
YARLMALALATAGIALVINIMVQMIWGFKIGPVPLGIIVGAIVFIGGHIFSTAINALGAFVHALRLHYVEFFGTFYSGEG
RRFEPFAARREISELKIEKPGGE

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane [H]

COG id: COG1269

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase 116 kDa subunit family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002490 [H]

Pfam domain/function: PF01496 V_ATPase_I [H]

EC number: 3.6.3.14

Molecular weight: Translated: 75446; Mature: 75446

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKPEEMVKIELISLARYRDIIMTYLHERGVVQLEEVPIEDIQHDAPNEYYRKATSYSIT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHCCCCCHHHHHHHCCCHHH
MGRLVDTLKGFLPPRKTSIKEFIFPKEREKRVYTYRGIEDLVKDVEKFLSEVEPKIREVE
HHHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCHHHHHHH
TQLTAINNRIANIREIINTLELLSSLNIEIEYLIPGSFLAIEVGKIERERVEKLIGELKN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECHHHHHHHHHHHHHHHH
ELGDKVFILRRDLGTISLLVVVTLKEFQGKLTSILAKYGFEKVEIPRERGHPRELIPKYN
HHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHH
ELLKEEMKKLEEIRKKGREFAEKYYEDLVFYKELMDNERDKANYLSYLARTELTVALVGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
LPKKNVEEVVEGIKNLTGGKVYINIREPEPNEIEEVPVKLKNPEFISQFEMLTEMYGVPK
CCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCC
YNELDPTPILAFTYSFFFGFMLTDFMYGLLLGIVSALLVKGHSKMKDGTWKFAKIMLWSS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VFTMLLGALFGSYFGNALDMAGFKVPRIMDAMEEALTVLIIALAIGLGHLFTGYVLGFIV
HHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
KWKNGDKVGAILDQLSWILIILGVTLFAISSRIDLPKLAWMSVFGAGAVLFIIGEFKNNG
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEEEEECCCCC
LMALLLVISDFFGFVGNWLSYARLMALALATAGIALVINIMVQMIWGFKIGPVPLGIIVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
AIVFIGGHIFSTAINALGAFVHALRLHYVEFFGTFYSGEGRRFEPFAARREISELKIEKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCC
GGE
CCC
>Mature Secondary Structure
MFKPEEMVKIELISLARYRDIIMTYLHERGVVQLEEVPIEDIQHDAPNEYYRKATSYSIT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHCCCCCHHHHHHHCCCHHH
MGRLVDTLKGFLPPRKTSIKEFIFPKEREKRVYTYRGIEDLVKDVEKFLSEVEPKIREVE
HHHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCHHHHHHH
TQLTAINNRIANIREIINTLELLSSLNIEIEYLIPGSFLAIEVGKIERERVEKLIGELKN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECHHHHHHHHHHHHHHHH
ELGDKVFILRRDLGTISLLVVVTLKEFQGKLTSILAKYGFEKVEIPRERGHPRELIPKYN
HHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHH
ELLKEEMKKLEEIRKKGREFAEKYYEDLVFYKELMDNERDKANYLSYLARTELTVALVGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
LPKKNVEEVVEGIKNLTGGKVYINIREPEPNEIEEVPVKLKNPEFISQFEMLTEMYGVPK
CCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCC
YNELDPTPILAFTYSFFFGFMLTDFMYGLLLGIVSALLVKGHSKMKDGTWKFAKIMLWSS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VFTMLLGALFGSYFGNALDMAGFKVPRIMDAMEEALTVLIIALAIGLGHLFTGYVLGFIV
HHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
KWKNGDKVGAILDQLSWILIILGVTLFAISSRIDLPKLAWMSVFGAGAVLFIIGEFKNNG
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEEEEECCCCC
LMALLLVISDFFGFVGNWLSYARLMALALATAGIALVINIMVQMIWGFKIGPVPLGIIVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
AIVFIGGHIFSTAINALGAFVHALRLHYVEFFGTFYSGEGRRFEPFAARREISELKIEKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCC
GGE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]