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The map label for this gene is ykuT [H]

Identifier: 18311626

GI number: 18311626

Start: 3016718

End: 3017578

Strand: Reverse

Name: ykuT [H]

Synonym: CPE2644

Alternate gene names: 18311626

Gene position: 3017578-3016718 (Counterclockwise)

Preceding gene: 18311627

Following gene: 18311625

Centisome position: 99.54

GC content: 27.53

Gene sequence:

>861_bases
ATGTTATTAGATAGTTTGCTTGGAATTAATTTTGAATTTGATCACATTAAGCTTGGGAAAATAAAGATATCTTTATCTAC
TATTGATTTTCTATTAAAAAAATTTATAACAATATGTGTCATAGTTATTTTTATGATTTTGGTAATTAAAATAGGAAGCA
AATTAATAGATAAAGCTGTACAAAAACAAATAGATACAAACTTTAAGTTCTCCTTAGACACAAGAAAGGCAAATACATTG
GGAACTTTATTAAAAAGTATTTTGATGTATTCAGTATATTTTATAGGTATAACAACTATATTATCTATTATATTTGGAAA
TATATCTTGGGCCTTTGCCTCTGTAGGAGGAGTAGCCGTAGGTTTAGGAGCTCAAAGTTTTGTTAAAGATGTAATAAATG
GGATATTTATACTTTTTGATAATCAATACAACGTTGGGGATTATGTAACCATAGAAGGTGTAAGTGGAATTGTAGAGGTA
ATAGGTCTTAGGACAACTGAGCTTAGGGATCAAGATGGTTCTCTTCATATTATTCCAAATGGAATGATAAGAATAGTAAC
AAATAATTGTAGAGGTGATATGAGAGTTCAGATTGATATTGGAATTTCATATAGCGATGATATAAATAAAGTAATAAACA
CTATAAACTCAGTTTGTGATACATATAATAAAGAAAATAATGATATAACAGAACCATTAAAGGTTTGGGGAGTTACAGAC
CTAACAAGTTCTAGTGTTAATCTTAGAATTTGTGGAAAAGTAAAATCCATGAAACTTTGGGAAACAGAAGTAGAGTTAAG
AAAGAGAATAAAAATGACTCTTGATAAAAAGAAATATATGAAAGAAATAATTACAGGTTAA

Upstream 100 bases:

>100_bases
AAACTTTAGAAATTAAATTTAAAAATATATATTCAATAACCAATAAAGGATTTGAAATATATAAATAATTATTTATTTCA
AAATCATAAGGGGTGGTTTA

Downstream 100 bases:

>100_bases
TTTATATAAATTTTATTTTAGAGGAGGTTATTTAATTTGATAAACAAATTTTATATTGGTGATATAGTTAAAATGAGGAA
AGTACATCCTTGTGGAAGTG

Product: mechanosensitive ion channel family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MLLDSLLGINFEFDHIKLGKIKISLSTIDFLLKKFITICVIVIFMILVIKIGSKLIDKAVQKQIDTNFKFSLDTRKANTL
GTLLKSILMYSVYFIGITTILSIIFGNISWAFASVGGVAVGLGAQSFVKDVINGIFILFDNQYNVGDYVTIEGVSGIVEV
IGLRTTELRDQDGSLHIIPNGMIRIVTNNCRGDMRVQIDIGISYSDDINKVINTINSVCDTYNKENNDITEPLKVWGVTD
LTSSSVNLRICGKVKSMKLWETEVELRKRIKMTLDKKKYMKEIITG

Sequences:

>Translated_286_residues
MLLDSLLGINFEFDHIKLGKIKISLSTIDFLLKKFITICVIVIFMILVIKIGSKLIDKAVQKQIDTNFKFSLDTRKANTL
GTLLKSILMYSVYFIGITTILSIIFGNISWAFASVGGVAVGLGAQSFVKDVINGIFILFDNQYNVGDYVTIEGVSGIVEV
IGLRTTELRDQDGSLHIIPNGMIRIVTNNCRGDMRVQIDIGISYSDDINKVINTINSVCDTYNKENNDITEPLKVWGVTD
LTSSSVNLRICGKVKSMKLWETEVELRKRIKMTLDKKKYMKEIITG
>Mature_286_residues
MLLDSLLGINFEFDHIKLGKIKISLSTIDFLLKKFITICVIVIFMILVIKIGSKLIDKAVQKQIDTNFKFSLDTRKANTL
GTLLKSILMYSVYFIGITTILSIIFGNISWAFASVGGVAVGLGAQSFVKDVINGIFILFDNQYNVGDYVTIEGVSGIVEV
IGLRTTELRDQDGSLHIIPNGMIRIVTNNCRGDMRVQIDIGISYSDDINKVINTINSVCDTYNKENNDITEPLKVWGVTD
LTSSSVNLRICGKVKSMKLWETEVELRKRIKMTLDKKKYMKEIITG

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=281, Percent_Identity=28.8256227758007, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI2367355, Length=195, Percent_Identity=28.2051282051282, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 31992; Mature: 31992

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLDSLLGINFEFDHIKLGKIKISLSTIDFLLKKFITICVIVIFMILVIKIGSKLIDKAV
CCCHHHHCCCEEECEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKQIDTNFKFSLDTRKANTLGTLLKSILMYSVYFIGITTILSIIFGNISWAFASVGGVAV
HHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCEEE
GLGAQSFVKDVINGIFILFDNQYNVGDYVTIEGVSGIVEVIGLRTTELRDQDGSLHIIPN
ECCHHHHHHHHHCCEEEEECCCCCCCCEEEECCHHHHHHHHCCCHHHCCCCCCCEEEECC
GMIRIVTNNCRGDMRVQIDIGISYSDDINKVINTINSVCDTYNKENNDITEPLKVWGVTD
CEEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCC
LTSSSVNLRICGKVKSMKLWETEVELRKRIKMTLDKKKYMKEIITG
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLDSLLGINFEFDHIKLGKIKISLSTIDFLLKKFITICVIVIFMILVIKIGSKLIDKAV
CCCHHHHCCCEEECEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKQIDTNFKFSLDTRKANTLGTLLKSILMYSVYFIGITTILSIIFGNISWAFASVGGVAV
HHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCEEE
GLGAQSFVKDVINGIFILFDNQYNVGDYVTIEGVSGIVEVIGLRTTELRDQDGSLHIIPN
ECCHHHHHHHHHCCEEEEECCCCCCCCEEEECCHHHHHHHHCCCHHHCCCCCCCEEEECC
GMIRIVTNNCRGDMRVQIDIGISYSDDINKVINTINSVCDTYNKENNDITEPLKVWGVTD
CEEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCC
LTSSSVNLRICGKVKSMKLWETEVELRKRIKMTLDKKKYMKEIITG
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]