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The map label for this gene is murA

Identifier: 18311588

GI number: 18311588

Start: 2982329

End: 2983582

Strand: Reverse

Name: murA

Synonym: CPE2606

Alternate gene names: 18311588

Gene position: 2983582-2982329 (Counterclockwise)

Preceding gene: 18311593

Following gene: 18311587

Centisome position: 98.42

GC content: 34.93

Gene sequence:

>1254_bases
ATGAATAGATTAATTATAAATGGCGGTAAAGCTTTAAAGGGATCTATAGAAATAAACGGAGCTAAAAATGCTGCCGTAGC
TATATTACCGGCAGCTATACTAGCTAGCAAAGGTGAATGTATTATTGATAATGTACCAGATATAGCTGATGTACATTGCT
TAGAGAGAATAATTAGATCATTAGGATGTAATGTTGAAAAATTAGATAATAACACATTAAAGATAAATGCTGAAGAAATA
AAAACTGTAGAAGCTTGTGGAAATGATGTAAGAAAAATGAGAGCTTCTTATTATTTCATAGGAGCACTTTTAGCACGTTT
TAAAGAGGCTAAAGTTGAACTTCCAGGAGGTTGTCCAATAGGAGTTAGACCTATTGACCAACATATAAAAGGATTTGAAG
CACTAGGAGCTAAGGTTTCAATAGAGCATGGTGCTGTAAATATAATGGCAGAAAAATTAATAGGAACAAATATATTCTTT
GACGTAGTAAGTGTTGGAGCTACTATAAACCTTATGATAGCGGCAACTTTAGCAGAAGGAACTACAGTGTTAGAAAATGC
TGCAAGAGAGCCACATGTAGTAGACGTAGCAAACTTTTTAAATGCTATGGGAGCTAATGTTAAAGGGGCAGGGACGGATG
TCATAAGAATCAAAGGTGTTAAGGAATTAAAAGGCTGTAATTATAGTGTTGTACCTGATCAAATAGAAGCAGGAACATTT
ATGATAGCAGCGGCAGCTACAAGAGGAGACGTAACAATTCAAAATGTTATACCAAAGCACTTAGAATCAATTTCAGCTAA
GCTTTTAGAAATGGGAGCTAAAGTAGAAGAGGGAGACGATAGTGTTAGAGTTTATGTTGATGGAGATTTAAAAGGAGTAA
ATTTAAAAACTGCTCCATATCCAGGATTCCCAACAGACGTTCAACAACCAATGTGTACTCTACTATCTACAGCTAAAGGT
AGAAGTATAATAGTTGAAACTATATGGGAAAATAGACATAAACATGTAGATGAACTTAAAAAAATGGGAGCTACTATAAA
AGTTGAAGGAAGATCAGCTATTATAGATGGTGTAGATAGACTTACAGGGGCTGTTGTTAAGGCTACTGACTTAAGAGCAG
GAGCTGCAATGGTTATCGCAGGTTTAATTTCTGATGGAGTTACAGAAATAACAAGTATTGAACACATAGATAGAGGATAC
CCTCATATAGAAGAAAAGTTCAGAATGCTTGGTGCTGATATAGTCAGAAAATAA

Upstream 100 bases:

>100_bases
TTAAATATGGTTAATCGAAATAAAAATTTTAACTAAACAAGAATAAAAAAGAAGAAAATGGTAATTGTATACATATAAAA
AATTAGCAAGGGTGAATTGT

Downstream 100 bases:

>100_bases
GAACAATAAATGGGGGAAATATATGATTTTTTGTTCACTATATAGTGGAAGCAGTGGTAATAGCATATTAGTAGGTTCAG
AAAAAACTAAAATACTAATT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MNRLIINGGKALKGSIEINGAKNAAVAILPAAILASKGECIIDNVPDIADVHCLERIIRSLGCNVEKLDNNTLKINAEEI
KTVEACGNDVRKMRASYYFIGALLARFKEAKVELPGGCPIGVRPIDQHIKGFEALGAKVSIEHGAVNIMAEKLIGTNIFF
DVVSVGATINLMIAATLAEGTTVLENAAREPHVVDVANFLNAMGANVKGAGTDVIRIKGVKELKGCNYSVVPDQIEAGTF
MIAAAATRGDVTIQNVIPKHLESISAKLLEMGAKVEEGDDSVRVYVDGDLKGVNLKTAPYPGFPTDVQQPMCTLLSTAKG
RSIIVETIWENRHKHVDELKKMGATIKVEGRSAIIDGVDRLTGAVVKATDLRAGAAMVIAGLISDGVTEITSIEHIDRGY
PHIEEKFRMLGADIVRK

Sequences:

>Translated_417_residues
MNRLIINGGKALKGSIEINGAKNAAVAILPAAILASKGECIIDNVPDIADVHCLERIIRSLGCNVEKLDNNTLKINAEEI
KTVEACGNDVRKMRASYYFIGALLARFKEAKVELPGGCPIGVRPIDQHIKGFEALGAKVSIEHGAVNIMAEKLIGTNIFF
DVVSVGATINLMIAATLAEGTTVLENAAREPHVVDVANFLNAMGANVKGAGTDVIRIKGVKELKGCNYSVVPDQIEAGTF
MIAAAATRGDVTIQNVIPKHLESISAKLLEMGAKVEEGDDSVRVYVDGDLKGVNLKTAPYPGFPTDVQQPMCTLLSTAKG
RSIIVETIWENRHKHVDELKKMGATIKVEGRSAIIDGVDRLTGAVVKATDLRAGAAMVIAGLISDGVTEITSIEHIDRGY
PHIEEKFRMLGADIVRK
>Mature_417_residues
MNRLIINGGKALKGSIEINGAKNAAVAILPAAILASKGECIIDNVPDIADVHCLERIIRSLGCNVEKLDNNTLKINAEEI
KTVEACGNDVRKMRASYYFIGALLARFKEAKVELPGGCPIGVRPIDQHIKGFEALGAKVSIEHGAVNIMAEKLIGTNIFF
DVVSVGATINLMIAATLAEGTTVLENAAREPHVVDVANFLNAMGANVKGAGTDVIRIKGVKELKGCNYSVVPDQIEAGTF
MIAAAATRGDVTIQNVIPKHLESISAKLLEMGAKVEEGDDSVRVYVDGDLKGVNLKTAPYPGFPTDVQQPMCTLLSTAKG
RSIIVETIWENRHKHVDELKKMGATIKVEGRSAIIDGVDRLTGAVVKATDLRAGAAMVIAGLISDGVTEITSIEHIDRGY
PHIEEKFRMLGADIVRK

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=418, Percent_Identity=47.3684210526316, Blast_Score=372, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA2_CLOPE (Q8XH79)

Other databases:

- EMBL:   BA000016
- RefSeq:   NP_563522.1
- ProteinModelPortal:   Q8XH79
- SMR:   Q8XH79
- GeneID:   990983
- GenomeReviews:   BA000016_GR
- KEGG:   cpe:CPE2606
- NMPDR:   fig|195102.1.peg.2669
- HOGENOM:   HBG482701
- OMA:   IDNIPDI
- PhylomeDB:   Q8XH79
- ProtClustDB:   PRK12830
- BioCyc:   CPER195102:CPE2606-MONOMER
- BRENDA:   2.5.1.7
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44533; Mature: 44533

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: ACT_SITE 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLIINGGKALKGSIEINGAKNAAVAILPAAILASKGECIIDNVPDIADVHCLERIIRS
CCEEEEECCCEEEEEEEECCCCCCEEEEHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHH
LGCNVEKLDNNTLKINAEEIKTVEACGNDVRKMRASYYFIGALLARFKEAKVELPGGCPI
HCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCC
GVRPIDQHIKGFEALGAKVSIEHGAVNIMAEKLIGTNIFFDVVSVGATINLMIAATLAEG
CCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCHHHHHHHHHCCEEEEEEEEEHHCC
TTVLENAAREPHVVDVANFLNAMGANVKGAGTDVIRIKGVKELKGCNYSVVPDQIEAGTF
HHHHHHCCCCCCEEHHHHHHHHHCCCCCCCCCCEEEECCHHHHCCCCCEECCCCCCCCEE
MIAAAATRGDVTIQNVIPKHLESISAKLLEMGAKVEEGDDSVRVYVDGDLKGVNLKTAPY
EEEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEECEEECCCC
PGFPTDVQQPMCTLLSTAKGRSIIVETIWENRHKHVDELKKMGATIKVEGRSAIIDGVDR
CCCCCCHHHHHHHHHHHCCCCEEEEHHHHCCHHHHHHHHHHCCCEEEECCCHHHHHHHHH
LTGAVVKATDLRAGAAMVIAGLISDGVTEITSIEHIDRGYPHIEEKFRMLGADIVRK
HHHHHEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRLIINGGKALKGSIEINGAKNAAVAILPAAILASKGECIIDNVPDIADVHCLERIIRS
CCEEEEECCCEEEEEEEECCCCCCEEEEHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHH
LGCNVEKLDNNTLKINAEEIKTVEACGNDVRKMRASYYFIGALLARFKEAKVELPGGCPI
HCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCC
GVRPIDQHIKGFEALGAKVSIEHGAVNIMAEKLIGTNIFFDVVSVGATINLMIAATLAEG
CCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCHHHHHHHHHCCEEEEEEEEEHHCC
TTVLENAAREPHVVDVANFLNAMGANVKGAGTDVIRIKGVKELKGCNYSVVPDQIEAGTF
HHHHHHCCCCCCEEHHHHHHHHHCCCCCCCCCCEEEECCHHHHCCCCCEECCCCCCCCEE
MIAAAATRGDVTIQNVIPKHLESISAKLLEMGAKVEEGDDSVRVYVDGDLKGVNLKTAPY
EEEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEECEEECCCC
PGFPTDVQQPMCTLLSTAKGRSIIVETIWENRHKHVDELKKMGATIKVEGRSAIIDGVDR
CCCCCCHHHHHHHHHHHCCCCEEEEHHHHCCHHHHHHHHHHCCCEEEECCCHHHHHHHHH
LTGAVVKATDLRAGAAMVIAGLISDGVTEITSIEHIDRGYPHIEEKFRMLGADIVRK
HHHHHEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11792842