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The map label for this gene is spoVC

Identifier: 18311467

GI number: 18311467

Start: 2845907

End: 2846473

Strand: Reverse

Name: spoVC

Synonym: CPE2485

Alternate gene names: 18311467

Gene position: 2846473-2845907 (Counterclockwise)

Preceding gene: 18311468

Following gene: 18311466

Centisome position: 93.9

GC content: 28.4

Gene sequence:

>567_bases
ATGATTTTAATAGTTGGATTAGGAAATCCGGGAAAACAATATGAGCAAACTAGACATAACATTGGATTTGATGTAATTGA
TTATATGGCAAATAAGTATAATATTGATGTAAATAGGGAAAAATTTAAAGGTATTTGTGGTGAAGGATTTATAGAGAATA
AAAAGGTTATTTTATTAAAACCTTTAACATATATGAATTTAAGTGGAGAAAGTATAAGAGAACTTGCTAACTTTTATAAG
TTAGAAGATGATGAAATAATAGTAGTTTATGATGATATAAGTTTAGATATAGGAAGATTAAGAATAAGAGAAAAAGGTAG
TGCTGGTGGGCATAATGGAATCAAGAGCATAATACAAAATCTTGGTGGAGATAAATTCCCAAGGGTTAAAGTGGGGGTAG
GACAACCTAAAGATAACTTAGTAAATCACGTTTTAGGAAAATTCTCAAAGGAAGATAGGGAACATATAGAAAAGGTTATT
CCAGTAGTAAGTGATGCAATAGTTGAAATTGTAAAAAATGATGCTAAGGAATCAATGAATAAATTTAATGGAGTTAATAT
AGAATAG

Upstream 100 bases:

>100_bases
ATTTAGTGAGGGGTTTTTTATTGTTTTATATTAATAGTAAAAGTATAATTAAAGAATGATTTAATTAAAAATTAAGAATT
TAATCAATATGGAGGTTAAT

Downstream 100 bases:

>100_bases
TTTATTTATTTTAGAATGGTGGTGTTTAGATTGAGGTTACAGGGGTTAATGGCTCCCTTATTAAATAGTGAGGCTTTTCA
AAAGGTTAAATCTTTTATGG

Product: peptidyl-tRNA hydrolase

Products: NA

Alternate protein names: PTH

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MILIVGLGNPGKQYEQTRHNIGFDVIDYMANKYNIDVNREKFKGICGEGFIENKKVILLKPLTYMNLSGESIRELANFYK
LEDDEIIVVYDDISLDIGRLRIREKGSAGGHNGIKSIIQNLGGDKFPRVKVGVGQPKDNLVNHVLGKFSKEDREHIEKVI
PVVSDAIVEIVKNDAKESMNKFNGVNIE

Sequences:

>Translated_188_residues
MILIVGLGNPGKQYEQTRHNIGFDVIDYMANKYNIDVNREKFKGICGEGFIENKKVILLKPLTYMNLSGESIRELANFYK
LEDDEIIVVYDDISLDIGRLRIREKGSAGGHNGIKSIIQNLGGDKFPRVKVGVGQPKDNLVNHVLGKFSKEDREHIEKVI
PVVSDAIVEIVKNDAKESMNKFNGVNIE
>Mature_188_residues
MILIVGLGNPGKQYEQTRHNIGFDVIDYMANKYNIDVNREKFKGICGEGFIENKKVILLKPLTYMNLSGESIRELANFYK
LEDDEIIVVYDDISLDIGRLRIREKGSAGGHNGIKSIIQNLGGDKFPRVKVGVGQPKDNLVNHVLGKFSKEDREHIEKVI
PVVSDAIVEIVKNDAKESMNKFNGVNIE

Specific function: The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis

COG id: COG0193

COG function: function code J; Peptidyl-tRNA hydrolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTH family

Homologues:

Organism=Homo sapiens, GI50897284, Length=179, Percent_Identity=29.0502793296089, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI1787455, Length=162, Percent_Identity=38.8888888888889, Blast_Score=101, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6321983, Length=185, Percent_Identity=23.7837837837838, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PTH_CLOP1 (Q0TMG7)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_697173.1
- ProteinModelPortal:   Q0TMG7
- SMR:   Q0TMG7
- STRING:   Q0TMG7
- GeneID:   4202173
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_2808
- TIGR:   CPF_2808
- eggNOG:   COG0193
- HOGENOM:   HBG610927
- OMA:   TAQSSEM
- ProtClustDB:   PRK05426
- BioCyc:   CPER195103:CPF_2808-MONOMER
- GO:   GO:0005737
- GO:   GO:0006412
- HAMAP:   MF_00083
- InterPro:   IPR001328
- InterPro:   IPR018171
- Gene3D:   G3DSA:3.40.50.1470
- PANTHER:   PTHR17224
- TIGRFAMs:   TIGR00447

Pfam domain/function: PF01195 Pept_tRNA_hydro; SSF53178 Pept_tRNA_hydro

EC number: =3.1.1.29

Molecular weight: Translated: 21130; Mature: 21130

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS01195 PEPT_TRNA_HYDROL_1; PS01196 PEPT_TRNA_HYDROL_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILIVGLGNPGKQYEQTRHNIGFDVIDYMANKYNIDVNREKFKGICGEGFIENKKVILLK
CEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCEEEEEC
PLTYMNLSGESIRELANFYKLEDDEIIVVYDDISLDIGRLRIREKGSAGGHNGIKSIIQN
CCCEECCCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHEEEECCCCCCCHHHHHHHHHH
LGGDKFPRVKVGVGQPKDNLVNHVLGKFSKEDREHIEKVIPVVSDAIVEIVKNDAKESMN
CCCCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFNGVNIE
HCCCCCCC
>Mature Secondary Structure
MILIVGLGNPGKQYEQTRHNIGFDVIDYMANKYNIDVNREKFKGICGEGFIENKKVILLK
CEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCEEEEEC
PLTYMNLSGESIRELANFYKLEDDEIIVVYDDISLDIGRLRIREKGSAGGHNGIKSIIQN
CCCEECCCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHEEEECCCCCCCHHHHHHHHHH
LGGDKFPRVKVGVGQPKDNLVNHVLGKFSKEDREHIEKVIPVVSDAIVEIVKNDAKESMN
CCCCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFNGVNIE
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA