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The map label for this gene is grxC [C]

Identifier: 18311419

GI number: 18311419

Start: 2785002

End: 2785229

Strand: Direct

Name: grxC [C]

Synonym: CPE2437

Alternate gene names: 18311419

Gene position: 2785002-2785229 (Clockwise)

Preceding gene: 18311418

Following gene: 18311427

Centisome position: 91.87

GC content: 28.51

Gene sequence:

>228_bases
ATGGTAAAGGTTTATTCAACAAACTCTTGTCCATGGTGCGTTAAAGCAAAACAATATCTTAAATCAAAAAATGTTGAATT
TGAAGATTTAAACGTACAAACAGATATGGTTGCTAGAGAAGATATGCTTAAAAAGAGTAAACAAATGGGTGTTCCTGTTT
TAGATATAAATGGAACTATTATAGTTGGTTTCGATAAAAATGCTATAGATAAAGCTTTAAATGAATAG

Upstream 100 bases:

>100_bases
TAAATAATTATTTTTTATTGATTTAAATCACATATTTTATACACTTTTAATACTTAAAATAAAGATATATTAAAAATTAA
TTCGCATAGGAGATGATAAT

Downstream 100 bases:

>100_bases
GAACATAGAAATAGAGAGATGTTTTTACATCTCTTTATTTTTTTGCAATAAAAAAGCTACAAGTAGAAATTTACTTGTAG
CTTTTTAGGTATAGGTTGAA

Product: glutaredoxin

Products: NA

Alternate protein names: ORF B [H]

Number of amino acids: Translated: 75; Mature: 75

Protein sequence:

>75_residues
MVKVYSTNSCPWCVKAKQYLKSKNVEFEDLNVQTDMVAREDMLKKSKQMGVPVLDINGTIIVGFDKNAIDKALNE

Sequences:

>Translated_75_residues
MVKVYSTNSCPWCVKAKQYLKSKNVEFEDLNVQTDMVAREDMLKKSKQMGVPVLDINGTIIVGFDKNAIDKALNE
>Mature_75_residues
MVKVYSTNSCPWCVKAKQYLKSKNVEFEDLNVQTDMVAREDMLKKSKQMGVPVLDINGTIIVGFDKNAIDKALNE

Specific function: The Disulfide Bond Functions As An Electron Carrier In The Glutathione-Dependent Synthesis Of Deoxyribonucleotides By The Enzyme Ribonucleotide Reductase. In Addition, It Is Also Involved In Reducing Some Disulfides In A Coupled System With Glutathione R

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR011911
- InterPro:   IPR002109
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 8482; Mature: 8482

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVYSTNSCPWCVKAKQYLKSKNVEFEDLNVQTDMVAREDMLKKSKQMGVPVLDINGTI
CEEEECCCCCCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHCCCEEEECCCEE
IVGFDKNAIDKALNE
EEEECCHHHHHHHCC
>Mature Secondary Structure
MVKVYSTNSCPWCVKAKQYLKSKNVEFEDLNVQTDMVAREDMLKKSKQMGVPVLDINGTI
CEEEECCCCCCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHCCCEEEECCCEE
IVGFDKNAIDKALNE
EEEECCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1637309 [H]