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The map label for this gene is sigH [H]

Identifier: 18311404

GI number: 18311404

Start: 2770748

End: 2771395

Strand: Reverse

Name: sigH [H]

Synonym: CPE2422

Alternate gene names: 18311404

Gene position: 2771395-2770748 (Counterclockwise)

Preceding gene: 18311405

Following gene: 18311403

Centisome position: 91.42

GC content: 28.09

Gene sequence:

>648_bases
ATGGGGATTACTTATGATTTGGCTAAAATCAATAATTATGAAGAATTTAAAGATTTAACAGATAAAGAAGTAGTTATGCT
AGCTAAAAATGGTGATAATATGGCTCAAGAATATGTAATAAGTAAGTATGAGCAGTTTGTAAAAGCTAAATCTAAATCAT
ATTTTCTTATAGGAGCAGATAAAGAAGATATATATCAAGAGGGAATGATTGGATTATATAAAGCAATAAGAGATTTTAAT
CCAGATAAGTTTGCATCATTTAAAAGTTTTGCAGAACTTTGTGTTACAAGGCAGATAATAACTGCTATAAAAACTGCAAC
AAGGCAAAAACATATCCCATTAAACACTTATATTTCTTTAAGCAAACCTATTTACGAGGAAGAATCTGATAGAACGCTTT
TAGATACTGTAGTAGGAATAACAATTACAGATCCTGAATCATTGGTCATAGGTAAAGAAGAGGTTGAAAAAATAGAAAGT
GCAATTAATAGTGTGCTTTCTGAACTAGAATTAGAGGTATTAAATTCTTATTTAGATGGTAAATCATATCAAGAAATTGC
CTGTGATTTAGATAGAGAAGCTAAATCTATAGATAATGCATTACAACGTGTAAAAAGAAAGCTTGAAAAATGTTTAAACA
TTAAATAA

Upstream 100 bases:

>100_bases
AAAAATGAGAAGAGGGTAATATTGACGAAGTCATATATAAACCTTATAATTTATTTGTAATTTATTGGATATTAGATTTT
TATCTGGGGGTGTAGAGAAT

Downstream 100 bases:

>100_bases
TGCAATTTTTTAAAAGTATTGACAAAGAATTTTATTAGTAGTAAAATTTTTATGGCATAGGTAAATTAAATGAATGTAAG
GTGCTCACGTAGCTCAGTCG

Product: RNA polymerase factor sigma-70

Products: NA

Alternate protein names: Sigma-30 [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MGITYDLAKINNYEEFKDLTDKEVVMLAKNGDNMAQEYVISKYEQFVKAKSKSYFLIGADKEDIYQEGMIGLYKAIRDFN
PDKFASFKSFAELCVTRQIITAIKTATRQKHIPLNTYISLSKPIYEEESDRTLLDTVVGITITDPESLVIGKEEVEKIES
AINSVLSELELEVLNSYLDGKSYQEIACDLDREAKSIDNALQRVKRKLEKCLNIK

Sequences:

>Translated_215_residues
MGITYDLAKINNYEEFKDLTDKEVVMLAKNGDNMAQEYVISKYEQFVKAKSKSYFLIGADKEDIYQEGMIGLYKAIRDFN
PDKFASFKSFAELCVTRQIITAIKTATRQKHIPLNTYISLSKPIYEEESDRTLLDTVVGITITDPESLVIGKEEVEKIES
AINSVLSELELEVLNSYLDGKSYQEIACDLDREAKSIDNALQRVKRKLEKCLNIK
>Mature_214_residues
GITYDLAKINNYEEFKDLTDKEVVMLAKNGDNMAQEYVISKYEQFVKAKSKSYFLIGADKEDIYQEGMIGLYKAIRDFNP
DKFASFKSFAELCVTRQIITAIKTATRQKHIPLNTYISLSKPIYEEESDRTLLDTVVGITITDPESLVIGKEEVEKIESA
INSVLSELELEVLNSYLDGKSYQEIACDLDREAKSIDNALQRVKRKLEKCLNIK

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in the transition to post-exponential phase in the beginning of sporulation [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014218
- InterPro:   IPR016371
- InterPro:   IPR000943
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 24548; Mature: 24417

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00622 HTH_LUXR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGITYDLAKINNYEEFKDLTDKEVVMLAKNGDNMAQEYVISKYEQFVKAKSKSYFLIGAD
CCCEECHHHCCCHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEECC
KEDIYQEGMIGLYKAIRDFNPDKFASFKSFAELCVTRQIITAIKTATRQKHIPLNTYISL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEC
SKPIYEEESDRTLLDTVVGITITDPESLVIGKEEVEKIESAINSVLSELELEVLNSYLDG
CCCCCCCCCCHHHHHHHHHCEECCCCHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KSYQEIACDLDREAKSIDNALQRVKRKLEKCLNIK
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GITYDLAKINNYEEFKDLTDKEVVMLAKNGDNMAQEYVISKYEQFVKAKSKSYFLIGAD
CCEECHHHCCCHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEECC
KEDIYQEGMIGLYKAIRDFNPDKFASFKSFAELCVTRQIITAIKTATRQKHIPLNTYISL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEC
SKPIYEEESDRTLLDTVVGITITDPESLVIGKEEVEKIESAINSVLSELELEVLNSYLDG
CCCCCCCCCCHHHHHHHHHCEECCCCHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KSYQEIACDLDREAKSIDNALQRVKRKLEKCLNIK
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3277943; 6322121 [H]