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The map label for this gene is nagA [H]

Identifier: 18311158

GI number: 18311158

Start: 2497278

End: 2498414

Strand: Direct

Name: nagA [H]

Synonym: CPE2176

Alternate gene names: 18311158

Gene position: 2497278-2498414 (Clockwise)

Preceding gene: 18311151

Following gene: 18311161

Centisome position: 82.38

GC content: 31.93

Gene sequence:

>1137_bases
ATGTTAATAAAAAACTGTAATATAGTATATTTAGATAAGATTGAAAAAGGAAATATACTTATAGAAAACGGAAAGATAAA
GGCTATAAATCCTAAAGAAGAATGTGATTGTGAAGTAATTGATGGAGAAGGCTTATTCCTATCTCCAGGATTTATAGATG
TTCATATACACGGTGCTGGTGGTCACGATACTATGGATGGTACTTATGAAGCTATAAATGAAATATCAAAGGTTATAGTT
AAACATGGTACTACTTCATTTTTACCAACAACAATGACTGTAGCTGCTGAAGACGTATGCAAGTCAATGGAAGCTATTCA
TAAAGCAAAAACTGAAGGAACAGATGGAGCTAATGTTTTAGGTGCTCACTTAGAAGGACCATTTATAAGCACAAGTGCAA
TAGGTGCTCAAAATCCTGATTTCTTAATCCCTCCAACAAAAGAAAACTTTTATAAATTAGTTGGAGAACATGAAGATGAT
GTTGTTTCAATAACTCTTGCTCCTGAAGTAGAAGGTGCTAAAGAACTTACTAAATTCTTAAGTGAAAAAGGTATAGTTGT
TTCAATGGGACATACTAAAGCTACTTATGAAGAAGCTATGGAAGGAATAAAGTGTGGATGCTCTCATGCCACTCATTTAT
TCAATGCAATGACTCCATTTACTCATAGAGAACCTGGAGTTGTAGGTGCTGTTTTTGATAGTGAAATAACTACTGAAACA
ATCTCAGATGGTATTCACATAGCATATCCAAGTTTAAGAGTTGCCTATAAACAAAAAGGAACAGATAAGGTTTTATTAAT
AACTGATGCTATGATGGCTTGCTGTATGCCTGATGGAATGTATTCATTAGGAGGACAAGATGTTGAAGTTAAAAATGGAG
CTGCAAGATTATTAAGTGGTTCTTTAGCAGGATCAATTTTAACTTTAGATGTGGCAGTTAAAAATATATTTAAAAACACT
AATTATCCACTTAATGAAGTTATAAAAATGGCTACTTATAACGGAGCTAAACACTGCAAAGTTGATGACAAAAAAGGATT
AATTAAAGAAGGCTATGATGCTGACTTAATTCTTTTTGATGATAATATAGATATAAAATATGTAATAGTTAATGGAAAAT
TAGTTCATAAAGCTTAA

Upstream 100 bases:

>100_bases
CTATTAATTATATCACAATTATTAAATTTAAATCATAGTGCTTATTTTGTTGACTTACACAAATTAAAATTTTAAGATTA
TTATGAGGAAGGTGATTCGT

Downstream 100 bases:

>100_bases
TATAAAAAAAGTACTTTGATTTTTCAAAGTGCTTTTTTATTTTATCTTAATCTTAAAATTAATAGTTCATCTTAAAATAA
TAAATTTATAGAAAAATAAT

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MLIKNCNIVYLDKIEKGNILIENGKIKAINPKEECDCEVIDGEGLFLSPGFIDVHIHGAGGHDTMDGTYEAINEISKVIV
KHGTTSFLPTTMTVAAEDVCKSMEAIHKAKTEGTDGANVLGAHLEGPFISTSAIGAQNPDFLIPPTKENFYKLVGEHEDD
VVSITLAPEVEGAKELTKFLSEKGIVVSMGHTKATYEEAMEGIKCGCSHATHLFNAMTPFTHREPGVVGAVFDSEITTET
ISDGIHIAYPSLRVAYKQKGTDKVLLITDAMMACCMPDGMYSLGGQDVEVKNGAARLLSGSLAGSILTLDVAVKNIFKNT
NYPLNEVIKMATYNGAKHCKVDDKKGLIKEGYDADLILFDDNIDIKYVIVNGKLVHKA

Sequences:

>Translated_378_residues
MLIKNCNIVYLDKIEKGNILIENGKIKAINPKEECDCEVIDGEGLFLSPGFIDVHIHGAGGHDTMDGTYEAINEISKVIV
KHGTTSFLPTTMTVAAEDVCKSMEAIHKAKTEGTDGANVLGAHLEGPFISTSAIGAQNPDFLIPPTKENFYKLVGEHEDD
VVSITLAPEVEGAKELTKFLSEKGIVVSMGHTKATYEEAMEGIKCGCSHATHLFNAMTPFTHREPGVVGAVFDSEITTET
ISDGIHIAYPSLRVAYKQKGTDKVLLITDAMMACCMPDGMYSLGGQDVEVKNGAARLLSGSLAGSILTLDVAVKNIFKNT
NYPLNEVIKMATYNGAKHCKVDDKKGLIKEGYDADLILFDDNIDIKYVIVNGKLVHKA
>Mature_378_residues
MLIKNCNIVYLDKIEKGNILIENGKIKAINPKEECDCEVIDGEGLFLSPGFIDVHIHGAGGHDTMDGTYEAINEISKVIV
KHGTTSFLPTTMTVAAEDVCKSMEAIHKAKTEGTDGANVLGAHLEGPFISTSAIGAQNPDFLIPPTKENFYKLVGEHEDD
VVSITLAPEVEGAKELTKFLSEKGIVVSMGHTKATYEEAMEGIKCGCSHATHLFNAMTPFTHREPGVVGAVFDSEITTET
ISDGIHIAYPSLRVAYKQKGTDKVLLITDAMMACCMPDGMYSLGGQDVEVKNGAARLLSGSLAGSILTLDVAVKNIFKNT
NYPLNEVIKMATYNGAKHCKVDDKKGLIKEGYDADLILFDDNIDIKYVIVNGKLVHKA

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=425, Percent_Identity=30.5882352941176, Blast_Score=191, Evalue=7e-49,
Organism=Homo sapiens, GI224922791, Length=422, Percent_Identity=30.0947867298578, Blast_Score=186, Evalue=3e-47,
Organism=Escherichia coli, GI1786892, Length=364, Percent_Identity=35.1648351648352, Blast_Score=196, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17553768, Length=395, Percent_Identity=33.9240506329114, Blast_Score=208, Evalue=3e-54,
Organism=Drosophila melanogaster, GI19920392, Length=397, Percent_Identity=31.7380352644836, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI281361140, Length=407, Percent_Identity=31.2039312039312, Blast_Score=177, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40810; Mature: 40810

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIKNCNIVYLDKIEKGNILIENGKIKAINPKEECDCEVIDGEGLFLSPGFIDVHIHGAG
CEEECCCEEEEEEECCCCEEEECCEEEEECCHHHCCEEEECCCCEEECCCEEEEEEECCC
GHDTMDGTYEAINEISKVIVKHGTTSFLPTTMTVAAEDVCKSMEAIHKAKTEGTDGANVL
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
GAHLEGPFISTSAIGAQNPDFLIPPTKENFYKLVGEHEDDVVSITLAPEVEGAKELTKFL
EECCCCCEEEECCCCCCCCCEEECCCHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHH
SEKGIVVSMGHTKATYEEAMEGIKCGCSHATHLFNAMTPFTHREPGVVGAVFDSEITTET
HCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHH
ISDGIHIAYPSLRVAYKQKGTDKVLLITDAMMACCMPDGMYSLGGQDVEVKNGAARLLSG
HCCCEEEECCCEEEEEECCCCCEEEEEEHHHHHHHCCCCHHHCCCCEEEECCCHHHHHHH
SLAGSILTLDVAVKNIFKNTNYPLNEVIKMATYNGAKHCKVDDKKGLIKEGYDADLILFD
CCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEECCCCCHHHCCCCCEEEEEE
DNIDIKYVIVNGKLVHKA
CCCCEEEEEECCEEEECC
>Mature Secondary Structure
MLIKNCNIVYLDKIEKGNILIENGKIKAINPKEECDCEVIDGEGLFLSPGFIDVHIHGAG
CEEECCCEEEEEEECCCCEEEECCEEEEECCHHHCCEEEECCCCEEECCCEEEEEEECCC
GHDTMDGTYEAINEISKVIVKHGTTSFLPTTMTVAAEDVCKSMEAIHKAKTEGTDGANVL
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
GAHLEGPFISTSAIGAQNPDFLIPPTKENFYKLVGEHEDDVVSITLAPEVEGAKELTKFL
EECCCCCEEEECCCCCCCCCEEECCCHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHH
SEKGIVVSMGHTKATYEEAMEGIKCGCSHATHLFNAMTPFTHREPGVVGAVFDSEITTET
HCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHH
ISDGIHIAYPSLRVAYKQKGTDKVLLITDAMMACCMPDGMYSLGGQDVEVKNGAARLLSG
HCCCEEEECCCEEEEEECCCCCEEEEEEHHHHHHHCCCCHHHCCCCEEEECCCHHHHHHH
SLAGSILTLDVAVKNIFKNTNYPLNEVIKMATYNGAKHCKVDDKKGLIKEGYDADLILFD
CCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEECCCCCHHHCCCCCEEEEEE
DNIDIKYVIVNGKLVHKA
CCCCEEEEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA