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The map label for this gene is selA [H]

Identifier: 18311099

GI number: 18311099

Start: 2429718

End: 2431106

Strand: Reverse

Name: selA [H]

Synonym: CPE2117

Alternate gene names: 18311099

Gene position: 2431106-2429718 (Counterclockwise)

Preceding gene: 18311100

Following gene: 18311098

Centisome position: 80.2

GC content: 30.53

Gene sequence:

>1389_bases
ATGACAAAAGAACTTCTTAGAGCTTTGCCTAAGATAGATGAAATACTTGGTATTTTTAATGAGGACTTTTTAAATGAAAA
TGGGAGAGAAACAATTGTAAGTGCTTTAAGAGATATAATCAATGAAAATAGGAAAGCTATTCTAAATGAAGAGGTAGATT
ATGCCTTAACTAAGGAAGAAGCTAAGAGTAAATGTGAGCATAGATTACTTAAAAAAAGAGAAAGAAATTTAAAAAGGGTT
ATTAATGGAACAGGTGTTGTTATTCATACTAATTTAGGAAGATCTTTGTTAAGCAAAGAGGCCACTGAAGCAGTTGCTTT
AGCCGCTTCAAGCTATAGCAATCTAGAGTATGATTTAGAAAAGGGAGAAAGAGGATCTAGATACTCCCTTATAGAAGGTA
TCATAAAAGATATTACAGGAGCTGAGGCAGCCTTAGTGGTAAATAATAATGCAGCGGCCATAATGCTTGTATTAAATTCT
CTTTGTGAAAATAAAGAGGTAATTGTTTCTAGAGGGGAACTTGTAGAAATAGGGGGCTCTTTTAGAATCCCAGAAGTGAT
GAATTTTTCAAGAGCTAAGCTTGTGGAAGTGGGAACAACCAATAGAACACATTTATATGATTATGAGGATGCTATAACAG
AGGAGACCGGAGCCTTTTTAAAAGTTCATAGTTCAAACTTTAAAATAGTAGGTTTTACTAAGAGTGTAAGTGCTAATGAT
ATATGTAACTTAGCAAAGGAAAAGGGTATACCTGTAATAGAGGACATTGGAAGTGGGGTTTTAATTGATTTAAGCAAATA
TGGATTAGAAAAAGAGCCTACAGTAATAGAAAGTTTAGAATCTGGAGTAGATATTGTAACATTCTCTGGAGATAAGATGC
TTGGTGGAGCACAGGCTGGAATTATTGTAGGTAAAAAGAAATTTATAGATAAAATAAAAAAGAATCAATTAACTAGAGCT
CTAAGAGTTGATAAATTTACTTTAGCTGCTTTAGAAATTACTTTAAAACATTATTTAAATGAAAAAGAGGCAATTGAAAA
AATACCAACTCTTTATATGATGACTTTAGATTTAAATGAAATAAAAGAAAGAGCTAATAGACTTTATAAGAATTTAGAAG
GGTTAAATAAGTTCTATAAATTTTCTATAGAAGAAGGTGAATCAACAGTTGGTGGAGGTTCAATGCCAGATAGTAAATTA
AGTACTTATTTACTTAGAATAGATTCAGATAGAATAAATGAAGTTAATTTAGAAAGAGAGTTAAGAGAATATAAAATACC
TATAATAACTAGAGTTTATAAAGGGGCAGTTTATATAGATCTTAGAACTATCTTAGAAGATGATTATGAAGTCATATTTA
ATGCTTTAAAGGAAATAGGTGAAAAATAG

Upstream 100 bases:

>100_bases
ACTAGATTAGAAAAGTTAGAGGTAGAAAGTGCTGTTATAGGACGTGTTGAAGATTTCAATGATGCATATATAGTAGTAGA
GTAATTTTTAGGAGGATAAC

Downstream 100 bases:

>100_bases
ATGAAACATGTGATTATAGGAACATCAGGTCATATAGATCATGGTAAAACAACTCTTATAAAGGCTTTAACAGGTAGAGA
AACTGATAAGATTGATGAGG

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MTKELLRALPKIDEILGIFNEDFLNENGRETIVSALRDIINENRKAILNEEVDYALTKEEAKSKCEHRLLKKRERNLKRV
INGTGVVIHTNLGRSLLSKEATEAVALAASSYSNLEYDLEKGERGSRYSLIEGIIKDITGAEAALVVNNNAAAIMLVLNS
LCENKEVIVSRGELVEIGGSFRIPEVMNFSRAKLVEVGTTNRTHLYDYEDAITEETGAFLKVHSSNFKIVGFTKSVSAND
ICNLAKEKGIPVIEDIGSGVLIDLSKYGLEKEPTVIESLESGVDIVTFSGDKMLGGAQAGIIVGKKKFIDKIKKNQLTRA
LRVDKFTLAALEITLKHYLNEKEAIEKIPTLYMMTLDLNEIKERANRLYKNLEGLNKFYKFSIEEGESTVGGGSMPDSKL
STYLLRIDSDRINEVNLERELREYKIPIITRVYKGAVYIDLRTILEDDYEVIFNALKEIGEK

Sequences:

>Translated_462_residues
MTKELLRALPKIDEILGIFNEDFLNENGRETIVSALRDIINENRKAILNEEVDYALTKEEAKSKCEHRLLKKRERNLKRV
INGTGVVIHTNLGRSLLSKEATEAVALAASSYSNLEYDLEKGERGSRYSLIEGIIKDITGAEAALVVNNNAAAIMLVLNS
LCENKEVIVSRGELVEIGGSFRIPEVMNFSRAKLVEVGTTNRTHLYDYEDAITEETGAFLKVHSSNFKIVGFTKSVSAND
ICNLAKEKGIPVIEDIGSGVLIDLSKYGLEKEPTVIESLESGVDIVTFSGDKMLGGAQAGIIVGKKKFIDKIKKNQLTRA
LRVDKFTLAALEITLKHYLNEKEAIEKIPTLYMMTLDLNEIKERANRLYKNLEGLNKFYKFSIEEGESTVGGGSMPDSKL
STYLLRIDSDRINEVNLERELREYKIPIITRVYKGAVYIDLRTILEDDYEVIFNALKEIGEK
>Mature_461_residues
TKELLRALPKIDEILGIFNEDFLNENGRETIVSALRDIINENRKAILNEEVDYALTKEEAKSKCEHRLLKKRERNLKRVI
NGTGVVIHTNLGRSLLSKEATEAVALAASSYSNLEYDLEKGERGSRYSLIEGIIKDITGAEAALVVNNNAAAIMLVLNSL
CENKEVIVSRGELVEIGGSFRIPEVMNFSRAKLVEVGTTNRTHLYDYEDAITEETGAFLKVHSSNFKIVGFTKSVSANDI
CNLAKEKGIPVIEDIGSGVLIDLSKYGLEKEPTVIESLESGVDIVTFSGDKMLGGAQAGIIVGKKKFIDKIKKNQLTRAL
RVDKFTLAALEITLKHYLNEKEAIEKIPTLYMMTLDLNEIKERANRLYKNLEGLNKFYKFSIEEGESTVGGGSMPDSKLS
TYLLRIDSDRINEVNLERELREYKIPIITRVYKGAVYIDLRTILEDDYEVIFNALKEIGEK

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=463, Percent_Identity=43.8444924406048, Blast_Score=334, Evalue=7e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 51767; Mature: 51636

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKELLRALPKIDEILGIFNEDFLNENGRETIVSALRDIINENRKAILNEEVDYALTKEE
CCHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHCCCHHHHCCHHH
AKSKCEHRLLKKRERNLKRVINGTGVVIHTNLGRSLLSKEATEAVALAASSYSNLEYDLE
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEECC
KGERGSRYSLIEGIIKDITGAEAALVVNNNAAAIMLVLNSLCENKEVIVSRGELVEIGGS
CCCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEECCCEEEECCC
FRIPEVMNFSRAKLVEVGTTNRTHLYDYEDAITEETGAFLKVHSSNFKIVGFTKSVSAND
CCCHHHHCCCHHEEEEECCCCCCEEECHHHHHHHCCCCEEEEECCCEEEEEEECCCCHHH
ICNLAKEKGIPVIEDIGSGVLIDLSKYGLEKEPTVIESLESGVDIVTFSGDKMLGGAQAG
HHHHHHHCCCCCHHHCCCCEEEEHHHCCCCCCCHHHHHHHCCCEEEEECCCCEECCCCCC
IIVGKKKFIDKIKKNQLTRALRVDKFTLAALEITLKHYLNEKEAIEKIPTLYMMTLDLNE
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEECCHHH
IKERANRLYKNLEGLNKFYKFSIEEGESTVGGGSMPDSKLSTYLLRIDSDRINEVNLERE
HHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCHHHHEEEEEECCCCCCCCCHHHH
LREYKIPIITRVYKGAVYIDLRTILEDDYEVIFNALKEIGEK
HHHHCCHHHHHHHCCEEEEEEHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKELLRALPKIDEILGIFNEDFLNENGRETIVSALRDIINENRKAILNEEVDYALTKEE
CHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHCCCHHHHCCHHH
AKSKCEHRLLKKRERNLKRVINGTGVVIHTNLGRSLLSKEATEAVALAASSYSNLEYDLE
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEECC
KGERGSRYSLIEGIIKDITGAEAALVVNNNAAAIMLVLNSLCENKEVIVSRGELVEIGGS
CCCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEECCCEEEECCC
FRIPEVMNFSRAKLVEVGTTNRTHLYDYEDAITEETGAFLKVHSSNFKIVGFTKSVSAND
CCCHHHHCCCHHEEEEECCCCCCEEECHHHHHHHCCCCEEEEECCCEEEEEEECCCCHHH
ICNLAKEKGIPVIEDIGSGVLIDLSKYGLEKEPTVIESLESGVDIVTFSGDKMLGGAQAG
HHHHHHHCCCCCHHHCCCCEEEEHHHCCCCCCCHHHHHHHCCCEEEEECCCCEECCCCCC
IIVGKKKFIDKIKKNQLTRALRVDKFTLAALEITLKHYLNEKEAIEKIPTLYMMTLDLNE
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEECCHHH
IKERANRLYKNLEGLNKFYKFSIEEGESTVGGGSMPDSKLSTYLLRIDSDRINEVNLERE
HHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCHHHHEEEEEECCCCCCCCCHHHH
LREYKIPIITRVYKGAVYIDLRTILEDDYEVIFNALKEIGEK
HHHHCCHHHHHHHCCEEEEEEHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA