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The map label for this gene is yesM [H]

Identifier: 18311070

GI number: 18311070

Start: 2395188

End: 2396924

Strand: Reverse

Name: yesM [H]

Synonym: CPE2088

Alternate gene names: 18311070

Gene position: 2396924-2395188 (Counterclockwise)

Preceding gene: 18311074

Following gene: 18311069

Centisome position: 79.07

GC content: 26.42

Gene sequence:

>1737_bases
ATGAAGTTTAGTAAGTCAAATCTTTATAAGAGACTGTTTATAACATATACAATAGTTATATTATCCGTAGTTAGTATTTT
ATGCATTTACTTCTTAAGTAAAACTTCTGAAGAGATTAAGAGAAATAATCTTTATTTAAATGATAAAATACTGCAAGATG
TAAATGAAACCTTAGAGTATAATAGCAGCACATCGAGAAGAATAATGAATATGCTATATGAAGATGACTTTAGGTTAAAT
GATGTTATAAAGTATTTAAATTCAGATTTAGTTGATTATATAAAAGGTAAATTAGATTACTATAGTGCAAGTGATAAACT
TTATTATAATGGTATAGAAAGTTTTGTTAAGAGTTCATTTCAATTAAACAACTTTTTAAAAAGTATATCATTTATAAGTT
ATTCTAGAAATGAAATATCAGTTTTTAATAGAAAGGGAGAAATAAAGACCTATCCTTTTAATTCAAATGAATTATTAGAC
AAAAAGGATATTGAATATGCAATCTATAATAAAAATGAGATTAGTATAATAAATGAAATAAGAGATGCAGCTTCTTTAAA
GCCAGAAGGAATGCTTATGACTACTTACGATGTAGGGGTAATTAGTGATGTTATAAAAAAATATAAGGATACAAATTCAG
AGGTTCTTATATTAAATAAAGAAGGAATGGTTTTATATGACTCAGAAAATAAATATGATTATGAGTATTATCCATACTTT
GATAAGCTTAAAGTAGGGCGTCATGAGATTTTATTAGAAGATAGTTATTATGTAGATATATTACCAGATAACAATGGATT
AATGTCTGTAGTTAGAATAAAAGTAAGCAATGCTACAAAAGTACCTCTTCTTTTTAAAGTTTCAGCATTCTTAGTTAGTT
TATTCTTATTTATAATTGCAGAGTGTGTTCTTTATATAAAATTTAAAAATTTAAGTAGTAGAATGGATTCTCTTGTTTTA
GCCATGGAAAAGGTTGAAAAAGGAGATATAGATGTTCATATTCCTTTAAGTAAGGATAGAGATGAAATAACATTTATTGC
AGATAATTTTAATAAAATGTGTGAAAAGTTAAATGATCATATAAGGAAGAGCTACTTAGCAGAATTACGTCAAAGAGAGG
CTGAAATTGTAGCCCTTCAAAATCAAATTAATCCACATTTTCTTTATAATACACTAGAGTCAATAAGGATGAAGGCAATA
TGTAATGGAGATAAAGAAGTAGGGAAAATGCTTTATAGTTTAGCATTTTTATTTAGAAGCCAAGTAAAGGGGAATCTTAT
AGTTTCAATAGATCAGGAAATAAAATACTGTAATAAATATTTAGAGCTATTTAAGTTTAGATATGATGAGAAATTTAAGT
TCAAAATAGAATGTGAAGAGGATTTATATGATAAGGGAATTGTTAAATTTACTCTTCAACCTTTAATTGAAAACTATTTT
GTTCATGGTATAAGGTTAGAAAGAGATGATAATGAATTAAAGATATATATCTATAAACATTTAGAAGATATAGTTGTGGA
AGTAATAGACAATGGTAGGGGAATTCCTAAGGAGAAATTAGATGATATAAATAGAAGAATTAGGGAATGCGATCATTCTG
GTAAATCAATAGGGATGCTAAATGTTCATGAAAGGATTAAAATTAAATATGGGGAACCTTATGGGTTAACTGTTACTAGT
GAGGAGAATAAGGGAACTAATATGATTTTAAAATTCCCGCTTAGAGAGGTGGAGTAG

Upstream 100 bases:

>100_bases
AAAAACAATAAAATATCATAATTTGATAAGCTTTTCAGATAGGGTAGAATATGATTTAATAAAAATTGACTAAGGTAATG
TGGGTGAAGAGGGGAATTAA

Downstream 100 bases:

>100_bases
TAATATGTACAAGGTTATGCTAGCTGATGATGAGAATTTAATTTTACAAGGACTTGAGAATATAATTGAATGGGAAGAAC
TAGGGTTAGAAATTGTAAAT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 578; Mature: 578

Protein sequence:

>578_residues
MKFSKSNLYKRLFITYTIVILSVVSILCIYFLSKTSEEIKRNNLYLNDKILQDVNETLEYNSSTSRRIMNMLYEDDFRLN
DVIKYLNSDLVDYIKGKLDYYSASDKLYYNGIESFVKSSFQLNNFLKSISFISYSRNEISVFNRKGEIKTYPFNSNELLD
KKDIEYAIYNKNEISIINEIRDAASLKPEGMLMTTYDVGVISDVIKKYKDTNSEVLILNKEGMVLYDSENKYDYEYYPYF
DKLKVGRHEILLEDSYYVDILPDNNGLMSVVRIKVSNATKVPLLFKVSAFLVSLFLFIIAECVLYIKFKNLSSRMDSLVL
AMEKVEKGDIDVHIPLSKDRDEITFIADNFNKMCEKLNDHIRKSYLAELRQREAEIVALQNQINPHFLYNTLESIRMKAI
CNGDKEVGKMLYSLAFLFRSQVKGNLIVSIDQEIKYCNKYLELFKFRYDEKFKFKIECEEDLYDKGIVKFTLQPLIENYF
VHGIRLERDDNELKIYIYKHLEDIVVEVIDNGRGIPKEKLDDINRRIRECDHSGKSIGMLNVHERIKIKYGEPYGLTVTS
EENKGTNMILKFPLREVE

Sequences:

>Translated_578_residues
MKFSKSNLYKRLFITYTIVILSVVSILCIYFLSKTSEEIKRNNLYLNDKILQDVNETLEYNSSTSRRIMNMLYEDDFRLN
DVIKYLNSDLVDYIKGKLDYYSASDKLYYNGIESFVKSSFQLNNFLKSISFISYSRNEISVFNRKGEIKTYPFNSNELLD
KKDIEYAIYNKNEISIINEIRDAASLKPEGMLMTTYDVGVISDVIKKYKDTNSEVLILNKEGMVLYDSENKYDYEYYPYF
DKLKVGRHEILLEDSYYVDILPDNNGLMSVVRIKVSNATKVPLLFKVSAFLVSLFLFIIAECVLYIKFKNLSSRMDSLVL
AMEKVEKGDIDVHIPLSKDRDEITFIADNFNKMCEKLNDHIRKSYLAELRQREAEIVALQNQINPHFLYNTLESIRMKAI
CNGDKEVGKMLYSLAFLFRSQVKGNLIVSIDQEIKYCNKYLELFKFRYDEKFKFKIECEEDLYDKGIVKFTLQPLIENYF
VHGIRLERDDNELKIYIYKHLEDIVVEVIDNGRGIPKEKLDDINRRIRECDHSGKSIGMLNVHERIKIKYGEPYGLTVTS
EENKGTNMILKFPLREVE
>Mature_578_residues
MKFSKSNLYKRLFITYTIVILSVVSILCIYFLSKTSEEIKRNNLYLNDKILQDVNETLEYNSSTSRRIMNMLYEDDFRLN
DVIKYLNSDLVDYIKGKLDYYSASDKLYYNGIESFVKSSFQLNNFLKSISFISYSRNEISVFNRKGEIKTYPFNSNELLD
KKDIEYAIYNKNEISIINEIRDAASLKPEGMLMTTYDVGVISDVIKKYKDTNSEVLILNKEGMVLYDSENKYDYEYYPYF
DKLKVGRHEILLEDSYYVDILPDNNGLMSVVRIKVSNATKVPLLFKVSAFLVSLFLFIIAECVLYIKFKNLSSRMDSLVL
AMEKVEKGDIDVHIPLSKDRDEITFIADNFNKMCEKLNDHIRKSYLAELRQREAEIVALQNQINPHFLYNTLESIRMKAI
CNGDKEVGKMLYSLAFLFRSQVKGNLIVSIDQEIKYCNKYLELFKFRYDEKFKFKIECEEDLYDKGIVKFTLQPLIENYF
VHGIRLERDDNELKIYIYKHLEDIVVEVIDNGRGIPKEKLDDINRRIRECDHSGKSIGMLNVHERIKIKYGEPYGLTVTS
EENKGTNMILKFPLREVE

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=206, Percent_Identity=28.1553398058252, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788723, Length=215, Percent_Identity=30.2325581395349, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67902; Mature: 67902

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSKSNLYKRLFITYTIVILSVVSILCIYFLSKTSEEIKRNNLYLNDKILQDVNETLEY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEECHHHHHHHHHHHHC
NSSTSRRIMNMLYEDDFRLNDVIKYLNSDLVDYIKGKLDYYSASDKLYYNGIESFVKSSF
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCEEHHHHHHHHHHHH
QLNNFLKSISFISYSRNEISVFNRKGEIKTYPFNSNELLDKKDIEYAIYNKNEISIINEI
HHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCEEEECCCCHHHHHHH
RDAASLKPEGMLMTTYDVGVISDVIKKYKDTNSEVLILNKEGMVLYDSENKYDYEYYPYF
HHHHCCCCCCEEEEEECHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCCCCEECCCH
DKLKVGRHEILLEDSYYVDILPDNNGLMSVVRIKVSNATKVPLLFKVSAFLVSLFLFIIA
HHHHCCCEEEEEECCEEEEEEECCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
ECVLYIKFKNLSSRMDSLVLAMEKVEKGDIDVHIPLSKDRDEITFIADNFNKMCEKLNDH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCHHHHHHHHHHH
IRKSYLAELRQREAEIVALQNQINPHFLYNTLESIRMKAICNGDKEVGKMLYSLAFLFRS
HHHHHHHHHHHCHHHEEEEHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QVKGNLIVSIDQEIKYCNKYLELFKFRYDEKFKFKIECEEDLYDKGIVKFTLQPLIENYF
HCCCCEEEEECHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHCCCCHHHHHHHHHHHHHH
VHGIRLERDDNELKIYIYKHLEDIVVEVIDNGRGIPKEKLDDINRRIRECDHSGKSIGML
HEEEEEEECCCCEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEE
NVHERIKIKYGEPYGLTVTSEENKGTNMILKFPLREVE
EECEEEEEEECCCEEEEEECCCCCCCEEEEECCCHHCC
>Mature Secondary Structure
MKFSKSNLYKRLFITYTIVILSVVSILCIYFLSKTSEEIKRNNLYLNDKILQDVNETLEY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEECHHHHHHHHHHHHC
NSSTSRRIMNMLYEDDFRLNDVIKYLNSDLVDYIKGKLDYYSASDKLYYNGIESFVKSSF
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCEEHHHHHHHHHHHH
QLNNFLKSISFISYSRNEISVFNRKGEIKTYPFNSNELLDKKDIEYAIYNKNEISIINEI
HHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCEEEECCCCHHHHHHH
RDAASLKPEGMLMTTYDVGVISDVIKKYKDTNSEVLILNKEGMVLYDSENKYDYEYYPYF
HHHHCCCCCCEEEEEECHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCCCCEECCCH
DKLKVGRHEILLEDSYYVDILPDNNGLMSVVRIKVSNATKVPLLFKVSAFLVSLFLFIIA
HHHHCCCEEEEEECCEEEEEEECCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
ECVLYIKFKNLSSRMDSLVLAMEKVEKGDIDVHIPLSKDRDEITFIADNFNKMCEKLNDH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCHHHHHHHHHHH
IRKSYLAELRQREAEIVALQNQINPHFLYNTLESIRMKAICNGDKEVGKMLYSLAFLFRS
HHHHHHHHHHHCHHHEEEEHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QVKGNLIVSIDQEIKYCNKYLELFKFRYDEKFKFKIECEEDLYDKGIVKFTLQPLIENYF
HCCCCEEEEECHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHCCCCHHHHHHHHHHHHHH
VHGIRLERDDNELKIYIYKHLEDIVVEVIDNGRGIPKEKLDDINRRIRECDHSGKSIGML
HEEEEEEECCCCEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEE
NVHERIKIKYGEPYGLTVTSEENKGTNMILKFPLREVE
EECEEEEEEECCCEEEEEECCCCCCCEEEEECCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]