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The map label for this gene is thiJ [C]

Identifier: 18311049

GI number: 18311049

Start: 2365174

End: 2365755

Strand: Reverse

Name: thiJ [C]

Synonym: CPE2067

Alternate gene names: 18311049

Gene position: 2365755-2365174 (Counterclockwise)

Preceding gene: 18311050

Following gene: 18311048

Centisome position: 78.04

GC content: 32.82

Gene sequence:

>582_bases
ATGGTCATGAAGAAAGTATTAGTATTTTTAGCAGAAGGTTTTGAGACTATAGAAGCATTATCTGTTGTAGATGTTTGTAA
CAGGGCTAAGGTAACATGTCATGCATGTAGCCTTACAGAAAACAGAACTGTTAATAGTGCTCATGGAACAATGGTGCTTT
GTGATAAATTAATATCAGATAATGATTTAGAAACTTATGATGCAATTATACTTCCAGGTGGAATGCCAGGAGCAACAAAT
CTTAGAGATAATGAGAGAGTACAATCATTAATAAAGAAATATAATAAAGAAAATAAAATTGTTGCTGCAATATGTGCTGC
TCCAATAGCTTTAGCTAAGGCTGGCGTTATTGAAGGAAAGAAGGTTACAAGTTATCCAGGGTTTAAAGAGGAACTTGGAA
ATGTTAATTATGTAGAAGAAGACACAGTAGTTGTGGATGGAAACATAATAACTAGTAGAGGACCTGCAACTGCCTTAGTA
TTTGGATTAGAAATATTAAAAAAGTTAGGATATGAAAAAGAAGCAGAGGAAATAAGAGAAGGAATGCTTATTAACTTTTT
CTTAGAAAAAGAAGGTAAGTAG

Upstream 100 bases:

>100_bases
TTGAAGATATTAAACTACAAAATAGAGCGGGAAGAGGAAGTAGTTTAATGATTTTAGTATTGGAAGACTACATAAGGGAC
GTAATTATTAAGTAGGAGGT

Downstream 100 bases:

>100_bases
AACTTTTATAATTTAAAGAGAGTTGTATCAAAATAACTTAAAAATAAAATTTATAAACATATTTGGAAAATTACTTAGTT
AATCTAAGAAGTTTATAGTA

Product: DJ-1 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MVMKKVLVFLAEGFETIEALSVVDVCNRAKVTCHACSLTENRTVNSAHGTMVLCDKLISDNDLETYDAIILPGGMPGATN
LRDNERVQSLIKKYNKENKIVAAICAAPIALAKAGVIEGKKVTSYPGFKEELGNVNYVEEDTVVVDGNIITSRGPATALV
FGLEILKKLGYEKEAEEIREGMLINFFLEKEGK

Sequences:

>Translated_193_residues
MVMKKVLVFLAEGFETIEALSVVDVCNRAKVTCHACSLTENRTVNSAHGTMVLCDKLISDNDLETYDAIILPGGMPGATN
LRDNERVQSLIKKYNKENKIVAAICAAPIALAKAGVIEGKKVTSYPGFKEELGNVNYVEEDTVVVDGNIITSRGPATALV
FGLEILKKLGYEKEAEEIREGMLINFFLEKEGK
>Mature_193_residues
MVMKKVLVFLAEGFETIEALSVVDVCNRAKVTCHACSLTENRTVNSAHGTMVLCDKLISDNDLETYDAIILPGGMPGATN
LRDNERVQSLIKKYNKENKIVAAICAAPIALAKAGVIEGKKVTSYPGFKEELGNVNYVEEDTVVVDGNIITSRGPATALV
FGLEILKKLGYEKEAEEIREGMLINFFLEKEGK

Specific function: Thiamine biosynthesis [C]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=187, Percent_Identity=33.1550802139037, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI31543380, Length=187, Percent_Identity=33.1550802139037, Blast_Score=100, Evalue=9e-22,
Organism=Escherichia coli, GI87081736, Length=183, Percent_Identity=31.6939890710383, Blast_Score=91, Evalue=4e-20,
Organism=Escherichia coli, GI87082219, Length=170, Percent_Identity=29.4117647058824, Blast_Score=64, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17531319, Length=188, Percent_Identity=37.7659574468085, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17558714, Length=175, Percent_Identity=34.8571428571429, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI28571932, Length=184, Percent_Identity=36.9565217391304, Blast_Score=130, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24653499, Length=190, Percent_Identity=35.2631578947368, Blast_Score=113, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 21056; Mature: 21056

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMKKVLVFLAEGFETIEALSVVDVCNRAKVTCHACSLTENRTVNSAHGTMVLCDKLISD
CHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCC
NDLETYDAIILPGGMPGATNLRDNERVQSLIKKYNKENKIVAAICAAPIALAKAGVIEGK
CCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCC
KVTSYPGFKEELGNVNYVEEDTVVVDGNIITSRGPATALVFGLEILKKLGYEKEAEEIRE
EECCCCCHHHHCCCCCEECCCCEEECCEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHC
GMLINFFLEKEGK
CCEEEEEEECCCC
>Mature Secondary Structure
MVMKKVLVFLAEGFETIEALSVVDVCNRAKVTCHACSLTENRTVNSAHGTMVLCDKLISD
CHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCC
NDLETYDAIILPGGMPGATNLRDNERVQSLIKKYNKENKIVAAICAAPIALAKAGVIEGK
CCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCC
KVTSYPGFKEELGNVNYVEEDTVVVDGNIITSRGPATALVFGLEILKKLGYEKEAEEIRE
EECCCCCHHHHCCCCCEECCCCEEECCEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHC
GMLINFFLEKEGK
CCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]