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The map label for this gene is ccpN [H]

Identifier: 18310994

GI number: 18310994

Start: 2306257

End: 2306889

Strand: Reverse

Name: ccpN [H]

Synonym: CPE2012

Alternate gene names: 18310994

Gene position: 2306889-2306257 (Counterclockwise)

Preceding gene: 18310995

Following gene: 18310993

Centisome position: 76.1

GC content: 33.65

Gene sequence:

>633_bases
TTGAAATTAACACCGAGGCAGGAAGAAATAGTTAGACTTGTAAAAGAGGGTCAACCAATAACTTCAGAAGCTTTAGCAGG
AAAGTTAGGGGTTACAAGAGCAGCCTTAAGACCAGATCTTGCAATACTTACAATGATTGGCGTATTAGATGCAAGACCAA
AGGTTGGGTATGTTTATTCAGATAAACCTTCGAACAGTTTCATCTATGAAAAAATAAAAAATATAAAGGTTAAAGACATA
ATGTCTAAACCGGTTACAGTATGTGAAGAAACTATGCTTCATGATGCTATAGTACATCTATTTTTAAATGATGTAGGAAC
TATGTTTGTAGAAAATGGAGGAGTTCTAACAGGAGCTGTTTCCAGAAAAGACTTTTTAAAGGTCGCTATAGGAGGAACAG
ATATTTATAAGGTTCCTGTTGGTGTTATAATGACAAGAATGCCTAACATAGTATGTGCTGTAGAAGAAGATTGCGCTTTT
GATGTAGCAAAAAAGATAATAGAACATGAAATAGACTCCGTACCAGTTGTAAAAAGAATTGAAGAAAATGAGGGAAAAGA
GAGATTAGAGATCATAGGAAAAATTTCTAAGACTAACATAACAAAGTTGTTTGTTAAGCTTGGAGAAAATTAA

Upstream 100 bases:

>100_bases
TAAAAAGATTTAGGTTGTGTTACAATTAATATATAAAAAAATCACTTTAATATAAAAAATCCTTTTTGTTCCTAGTTTAT
TTAAGGAAGGAGCATTCAAA

Downstream 100 bases:

>100_bases
ATTTATGGTTAAAAAGAAAGATTAAATGGGTAACTATCGGGGGTAATACTCTGTTAGTATATAAAAATTCAACTATAGTA
TTGAACGGAGGAGTATTGAG

Product: CBS domain protein

Products: NA

Alternate protein names: Catabolite control protein N; Control catabolite protein of gluconeogenesis [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MKLTPRQEEIVRLVKEGQPITSEALAGKLGVTRAALRPDLAILTMIGVLDARPKVGYVYSDKPSNSFIYEKIKNIKVKDI
MSKPVTVCEETMLHDAIVHLFLNDVGTMFVENGGVLTGAVSRKDFLKVAIGGTDIYKVPVGVIMTRMPNIVCAVEEDCAF
DVAKKIIEHEIDSVPVVKRIEENEGKERLEIIGKISKTNITKLFVKLGEN

Sequences:

>Translated_210_residues
MKLTPRQEEIVRLVKEGQPITSEALAGKLGVTRAALRPDLAILTMIGVLDARPKVGYVYSDKPSNSFIYEKIKNIKVKDI
MSKPVTVCEETMLHDAIVHLFLNDVGTMFVENGGVLTGAVSRKDFLKVAIGGTDIYKVPVGVIMTRMPNIVCAVEEDCAF
DVAKKIIEHEIDSVPVVKRIEENEGKERLEIIGKISKTNITKLFVKLGEN
>Mature_210_residues
MKLTPRQEEIVRLVKEGQPITSEALAGKLGVTRAALRPDLAILTMIGVLDARPKVGYVYSDKPSNSFIYEKIKNIKVKDI
MSKPVTVCEETMLHDAIVHLFLNDVGTMFVENGGVLTGAVSRKDFLKVAIGGTDIYKVPVGVIMTRMPNIVCAVEEDCAF
DVAKKIIEHEIDSVPVVKRIEENEGKERLEIIGKISKTNITKLFVKLGEN

Specific function: Transcription repressor that binds to the promoter of gapB and pckA genes, preventing their expression. Acts as a regulator for catabolite repression of gluconeogenic genes [H]

COG id: COG0517

COG function: function code R; FOG: CBS domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR013196
- InterPro:   IPR001034
- InterPro:   IPR016842
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00571 CBS; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 23208; Mature: 23208

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTPRQEEIVRLVKEGQPITSEALAGKLGVTRAALRPDLAILTMIGVLDARPKVGYVYS
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEC
DKPSNSFIYEKIKNIKVKDIMSKPVTVCEETMLHDAIVHLFLNDVGTMFVENGGVLTGAV
CCCCCHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEECC
SRKDFLKVAIGGTDIYKVPVGVIMTRMPNIVCAVEEDCAFDVAKKIIEHEIDSVPVVKRI
CCCCEEEEEECCCEEEHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHH
EENEGKERLEIIGKISKTNITKLFVKLGEN
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLTPRQEEIVRLVKEGQPITSEALAGKLGVTRAALRPDLAILTMIGVLDARPKVGYVYS
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEC
DKPSNSFIYEKIKNIKVKDIMSKPVTVCEETMLHDAIVHLFLNDVGTMFVENGGVLTGAV
CCCCCHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEECC
SRKDFLKVAIGGTDIYKVPVGVIMTRMPNIVCAVEEDCAFDVAKKIIEHEIDSVPVVKRI
CCCCEEEEEECCCEEEHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHH
EENEGKERLEIIGKISKTNITKLFVKLGEN
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]