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The map label for this gene is hflX [H]

Identifier: 18310941

GI number: 18310941

Start: 2247237

End: 2249030

Strand: Reverse

Name: hflX [H]

Synonym: CPE1959

Alternate gene names: 18310941

Gene position: 2249030-2247237 (Counterclockwise)

Preceding gene: 18310943

Following gene: 18310940

Centisome position: 74.19

GC content: 30.38

Gene sequence:

>1794_bases
ATGATACATGGAAATACTGATGGAATAAGGAATTCAGTACTTAAAGAATTAGAAGAACTTTATAAAATAAATGTACCAAA
ATATAGTGTTTGTACAGAGGATATGATAAATATTATTTCTAGATTATCTTCTCAAATAGAAAGAGAAATTAGTGTAGGAA
TAAATAGAAAAGGAAAGGTAATTAGTGTAGCTATAGGAGATTCTTCAAGTGTAGAGATTCCATTAATAGATATACACGAA
AAAAGATTATCTGGAGTTAGAATAATACATACTCATCCAAGTGGGGTTTCTAGACTTTCTGCTTTAGATATATCTGCCCT
TATGAAATTAAAACTTGATACAATAATGGCCATAGCTGTAGAGGAAGGCAAGGCTAAAGATGCTTCTTTAGGATTTTGTT
ATGTAGAAAATGAAATTCTTATAAGTGAAGAAGCTCCTCATTTAACTATAGATAAGTGCTTACAAATTAATATTTTAGAT
AAGATTAATCATGTTGAAGAAGTTATTAAAACAAGCAATGTTGAGGAAGATGATAGTGAAAGAGCTATTTTAGTAGGATG
TGATACAAGAGAAAGTTTAGATGAGTTAGAGGAACTTGCTAAGGCTTGTGATATTCCTACATTAGAAAAGGTATTTCAAA
ATAGAAGTAAAATAGATGCTTCTTTTTATATAGGAAGAGGTAAAGTTTTAGAAATTGCTAACATAAGACAATTAACAAGA
GCTAACTTAGTAATTTTTGATGATGAATTATCAGGGGCACAAGTTAAGAACCTTGAAGCTAACTTAGGAGTTAAGGTAAT
TGATAGAACAACTCTTATTTTAGAAATATTCTCAAGAAGAGCTAAGACAAGAGAAGCTAAAATTCAAGTAGAACTTGCTC
AGCTTAAGTATAGAGCAGCTAGGCTTATGGGACTTGGAACTGTTATGTCTAGAACTGGTGGTGGAATAGGAACAAGAGGA
CCAGGGGAAAAGAAACTTGAAATAGATAGAAGACATATAAGAGAAAGAATATATGATCTTCAAGCTGAGCTTAAAAAAAT
AAAGAAGATAAGAGAAACTCAAAGAGAGAGAAGAAGTAAGGATAAAACTTCACAGGTTTCCTTAGTTGGATATACTAACG
CAGGAAAATCTACTTTAAGAAATACTCTATGTGCAGAATCAGCTTCAACTTTAGCTACTCAAGCTAAGGATAAGGTTTTT
GAAGCAGATATGCTTTTTGCAACTTTAGATACTACAACAAGGGCTATAAAACTTCCTGATAATAGGGACATAACATTAAC
AGATACAGTTGGATTTGTAAGCAAACTTCCTCATGAATTAGTTGAAGCTTTTAAGTCAACTTTAGAAGAAGTTATATACT
CAGATCTTTTATGCCATGTTGTAGATGCTTCCTCAGATAATGCACAAGAAGAAATTATAGCTGTAGAAAAAGTATTAGGT
GAATTAAAAGCCTTAGAATCAGCAAAGATATTAGTTCTTAATAAAATTGATAAGGCTGATGAAGAAAAGCTAAATGAATT
AGAAGCAAAATATTCTTCAATATATAATAAGGTAGTAAAAATTTCTGCTAGAGAAAGAATAAACTTAGATGATTTATTAG
AAGCAATAAGTGAAGAATTACCTTATACATTAAAAAGTAAGGAATATATAATTCCTTATACAGCTCAACAAGTTGTAGCT
TATCTTCATAGAAATGCTAATGTAAGTGAAGAAGAATATAGAGAAGAGGGAACTTATATAAAAGCAGAAGTGGATGAAGA
AGTAGAAAATAAATGTAGAGAATACGAGTTATAA

Upstream 100 bases:

>100_bases
CTCCCCTAACTATTCCGTATTATTTACAATATTGTATTTATAGTATAAAATTAAATGAAAATTGTCAAGAAACATAATAA
ATATCACGAGGTGGTAATAT

Downstream 100 bases:

>100_bases
TAAGAGTATTAAATTCATGAGTAAAAGCTAAATTCAACAAGAATTTAGCTTTTATTATTACAATTGTCACATCATAAATT
ATAATATATATAAGTATAAT

Product: GTP binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 597; Mature: 597

Protein sequence:

>597_residues
MIHGNTDGIRNSVLKELEELYKINVPKYSVCTEDMINIISRLSSQIEREISVGINRKGKVISVAIGDSSSVEIPLIDIHE
KRLSGVRIIHTHPSGVSRLSALDISALMKLKLDTIMAIAVEEGKAKDASLGFCYVENEILISEEAPHLTIDKCLQINILD
KINHVEEVIKTSNVEEDDSERAILVGCDTRESLDELEELAKACDIPTLEKVFQNRSKIDASFYIGRGKVLEIANIRQLTR
ANLVIFDDELSGAQVKNLEANLGVKVIDRTTLILEIFSRRAKTREAKIQVELAQLKYRAARLMGLGTVMSRTGGGIGTRG
PGEKKLEIDRRHIRERIYDLQAELKKIKKIRETQRERRSKDKTSQVSLVGYTNAGKSTLRNTLCAESASTLATQAKDKVF
EADMLFATLDTTTRAIKLPDNRDITLTDTVGFVSKLPHELVEAFKSTLEEVIYSDLLCHVVDASSDNAQEEIIAVEKVLG
ELKALESAKILVLNKIDKADEEKLNELEAKYSSIYNKVVKISARERINLDDLLEAISEELPYTLKSKEYIIPYTAQQVVA
YLHRNANVSEEEYREEGTYIKAEVDEEVENKCREYEL

Sequences:

>Translated_597_residues
MIHGNTDGIRNSVLKELEELYKINVPKYSVCTEDMINIISRLSSQIEREISVGINRKGKVISVAIGDSSSVEIPLIDIHE
KRLSGVRIIHTHPSGVSRLSALDISALMKLKLDTIMAIAVEEGKAKDASLGFCYVENEILISEEAPHLTIDKCLQINILD
KINHVEEVIKTSNVEEDDSERAILVGCDTRESLDELEELAKACDIPTLEKVFQNRSKIDASFYIGRGKVLEIANIRQLTR
ANLVIFDDELSGAQVKNLEANLGVKVIDRTTLILEIFSRRAKTREAKIQVELAQLKYRAARLMGLGTVMSRTGGGIGTRG
PGEKKLEIDRRHIRERIYDLQAELKKIKKIRETQRERRSKDKTSQVSLVGYTNAGKSTLRNTLCAESASTLATQAKDKVF
EADMLFATLDTTTRAIKLPDNRDITLTDTVGFVSKLPHELVEAFKSTLEEVIYSDLLCHVVDASSDNAQEEIIAVEKVLG
ELKALESAKILVLNKIDKADEEKLNELEAKYSSIYNKVVKISARERINLDDLLEAISEELPYTLKSKEYIIPYTAQQVVA
YLHRNANVSEEEYREEGTYIKAEVDEEVENKCREYEL
>Mature_597_residues
MIHGNTDGIRNSVLKELEELYKINVPKYSVCTEDMINIISRLSSQIEREISVGINRKGKVISVAIGDSSSVEIPLIDIHE
KRLSGVRIIHTHPSGVSRLSALDISALMKLKLDTIMAIAVEEGKAKDASLGFCYVENEILISEEAPHLTIDKCLQINILD
KINHVEEVIKTSNVEEDDSERAILVGCDTRESLDELEELAKACDIPTLEKVFQNRSKIDASFYIGRGKVLEIANIRQLTR
ANLVIFDDELSGAQVKNLEANLGVKVIDRTTLILEIFSRRAKTREAKIQVELAQLKYRAARLMGLGTVMSRTGGGIGTRG
PGEKKLEIDRRHIRERIYDLQAELKKIKKIRETQRERRSKDKTSQVSLVGYTNAGKSTLRNTLCAESASTLATQAKDKVF
EADMLFATLDTTTRAIKLPDNRDITLTDTVGFVSKLPHELVEAFKSTLEEVIYSDLLCHVVDASSDNAQEEIIAVEKVLG
ELKALESAKILVLNKIDKADEEKLNELEAKYSSIYNKVVKISARERINLDDLLEAISEELPYTLKSKEYIIPYTAQQVVA
YLHRNANVSEEEYREEGTYIKAEVDEEVENKCREYEL

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=216, Percent_Identity=34.7222222222222, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI310124267, Length=216, Percent_Identity=34.7222222222222, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI310124171, Length=216, Percent_Identity=34.7222222222222, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI310124169, Length=216, Percent_Identity=34.7222222222222, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI310133118, Length=224, Percent_Identity=33.9285714285714, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI310133116, Length=224, Percent_Identity=34.375, Blast_Score=115, Evalue=1e-25,
Organism=Escherichia coli, GI1790615, Length=410, Percent_Identity=40, Blast_Score=262, Evalue=5e-71,
Organism=Caenorhabditis elegans, GI17561038, Length=330, Percent_Identity=32.1212121212121, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24650079, Length=365, Percent_Identity=32.0547945205479, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 67080; Mature: 67080

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHGNTDGIRNSVLKELEELYKINVPKYSVCTEDMINIISRLSSQIEREISVGINRKGKV
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
ISVAIGDSSSVEIPLIDIHEKRLSGVRIIHTHPSGVSRLSALDISALMKLKLDTIMAIAV
EEEEECCCCCCEEEEEECCHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEEEE
EEGKAKDASLGFCYVENEILISEEAPHLTIDKCLQINILDKINHVEEVIKTSNVEEDDSE
CCCCCCCCCEEEEEEECEEEEECCCCCCCHHHHEEEHHHHHHHHHHHHHHHCCCCCCCCC
RAILVGCDTRESLDELEELAKACDIPTLEKVFQNRSKIDASFYIGRGKVLEIANIRQLTR
CEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHCCHHCCCEEEEECCCCEEEHHHHHHHHH
ANLVIFDDELSGAQVKNLEANLGVKVIDRTTLILEIFSRRAKTREAKIQVELAQLKYRAA
CCEEEEECCCCCCEEECCCCCCCEEEEHHHHHHHHHHHHHHHCCHHHEEEHHHHHHHHHH
RLMGLGTVMSRTGGGIGTRGPGEKKLEIDRRHIRERIYDLQAELKKIKKIRETQRERRSK
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DKTSQVSLVGYTNAGKSTLRNTLCAESASTLATQAKDKVFEADMLFATLDTTTRAIKLPD
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEECCC
NRDITLTDTVGFVSKLPHELVEAFKSTLEEVIYSDLLCHVVDASSDNAQEEIIAVEKVLG
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ELKALESAKILVLNKIDKADEEKLNELEAKYSSIYNKVVKISARERINLDDLLEAISEEL
HHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
PYTLKSKEYIIPYTAQQVVAYLHRNANVSEEEYREEGTYIKAEVDEEVENKCREYEL
CCEECCCCEEECCCHHHHHHHHHCCCCCCHHHHHHCCCEEEEECCHHHHHHHHCCCC
>Mature Secondary Structure
MIHGNTDGIRNSVLKELEELYKINVPKYSVCTEDMINIISRLSSQIEREISVGINRKGKV
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
ISVAIGDSSSVEIPLIDIHEKRLSGVRIIHTHPSGVSRLSALDISALMKLKLDTIMAIAV
EEEEECCCCCCEEEEEECCHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEEEE
EEGKAKDASLGFCYVENEILISEEAPHLTIDKCLQINILDKINHVEEVIKTSNVEEDDSE
CCCCCCCCCEEEEEEECEEEEECCCCCCCHHHHEEEHHHHHHHHHHHHHHHCCCCCCCCC
RAILVGCDTRESLDELEELAKACDIPTLEKVFQNRSKIDASFYIGRGKVLEIANIRQLTR
CEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHCCHHCCCEEEEECCCCEEEHHHHHHHHH
ANLVIFDDELSGAQVKNLEANLGVKVIDRTTLILEIFSRRAKTREAKIQVELAQLKYRAA
CCEEEEECCCCCCEEECCCCCCCEEEEHHHHHHHHHHHHHHHCCHHHEEEHHHHHHHHHH
RLMGLGTVMSRTGGGIGTRGPGEKKLEIDRRHIRERIYDLQAELKKIKKIRETQRERRSK
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DKTSQVSLVGYTNAGKSTLRNTLCAESASTLATQAKDKVFEADMLFATLDTTTRAIKLPD
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEECCC
NRDITLTDTVGFVSKLPHELVEAFKSTLEEVIYSDLLCHVVDASSDNAQEEIIAVEKVLG
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ELKALESAKILVLNKIDKADEEKLNELEAKYSSIYNKVVKISARERINLDDLLEAISEEL
HHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
PYTLKSKEYIIPYTAQQVVAYLHRNANVSEEEYREEGTYIKAEVDEEVENKCREYEL
CCEECCCCEEECCCHHHHHHHHHCCCCCCHHHHHHCCCEEEEECCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]