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The map label for this gene is pqqL [C]

Identifier: 18310906

GI number: 18310906

Start: 2204674

End: 2205918

Strand: Reverse

Name: pqqL [C]

Synonym: CPE1924

Alternate gene names: 18310906

Gene position: 2205918-2204674 (Counterclockwise)

Preceding gene: 18310909

Following gene: 18310905

Centisome position: 72.77

GC content: 28.35

Gene sequence:

>1245_bases
ATGAAAAGATGGACATTTGATGAAAATACCATAATTTTACCCAATGGGCTAAAAGTTATAACAATAAAAAAAGATACAAG
GTTAGCATCTATAAATATTGGTGTTAATATAGGATCTTTATATGAAGACGAAAAAGAATTAGGCATGAGTCACTTTGTTG
AGCACATGCTTTTTAAAGGAACAAAGAATAGAAGTAATGAACAATTAAATAGAGAATTAGAATTTTTAGGTGGAGATTAT
AATGCATATACAGATTATATTTCAACAGTATATAGCATTACTTGTCTAGATGAGGAATTTGAAAAGGGAATAGAACTTTT
AAGTGATATGGTTTTAAATTCTTCCTTTGATGAAAAAGAGATGAAAAAGGAAAAGGGCGTTGTTTTATCAGAGATAAAAA
GTGATAAGGATGATATTGAAGATTTAAGTATTAGCAGAACTCATGAATATGCTTTTGATAAATCAGCACTTAAAAATTCT
ATTGCAGGAACTGAAGAACATGTTAAGGGATTTAAAAGAAAGCAGGTTTATGATTTTTATAAAAAATATTATACTCCTGA
CAATTGTGTTATTGTAACTGTAAGTGCCTTTAGTCATGAACAAATGCAAAAAATAATAATAGACTTATTTGGAAAATGGG
AAGGAAAATCCCATAAAAAAGCTGAAATAATAAAAGAAGAAAATAAAGAGTTAATAAAAACAACTTACAAATCTCAAATA
GAGCAAGGAACTGTTACTTATCTTTATGCCTTTAAAGAGGTTTGCGAAAAGGATAAACTTCCATTAAAGATATTAAGTTA
TAAGTTAGCTGAAAGTTCAAACTCAATATTATTTAGAGAGCTTAGAGAAGAGCGTGGATTAGCTTATGATGTATATAGTC
AAATGGATTTAGACGAAAATGTAAATACAATGAATATTTTTACCTCAGTTAGAGAAGAATCCATAGATGAGGTAATAGAA
GTAATAGACAAAGCCATATTAGACATAAAAAATAAAGATATAAACTTTGATGAAGATATGCTTTGCATGATGAAAAAGAC
TCATAAGACAGGAGTAGTTTCTACCTTAGAAGATTGTAGCAGTTTATGCAGTTATGTATTAGTTCAAAGCTTAGCGGGAA
AAGATATAACTGAGTTTATAAATAGCATGGAAGAATTAGAAACTTTAACTGGGGAAGATATCTATAGGGTTTGTAATAAA
TATTTGAATAAGCCTACTATACACATATTAAAACCAATGGAGTAG

Upstream 100 bases:

>100_bases
ATTCATATAACCACCAACCTTTAAAAAATATTGTTTTAACTTACTTAATATTATACAATGAAAACTAAGGTTTATATAAA
TAATTTTAGGGGAGTTTTTA

Downstream 100 bases:

>100_bases
ATAAAATGGGAAAAATAACAAGTATAGAAGTTCAAAAGAGAAATGTAAATAGAGTAAATGTTTATGTGGATGAAGCCTTT
ACCTTTGCTTGTGATGCTGA

Product: peptidase, M16 family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MKRWTFDENTIILPNGLKVITIKKDTRLASINIGVNIGSLYEDEKELGMSHFVEHMLFKGTKNRSNEQLNRELEFLGGDY
NAYTDYISTVYSITCLDEEFEKGIELLSDMVLNSSFDEKEMKKEKGVVLSEIKSDKDDIEDLSISRTHEYAFDKSALKNS
IAGTEEHVKGFKRKQVYDFYKKYYTPDNCVIVTVSAFSHEQMQKIIIDLFGKWEGKSHKKAEIIKEENKELIKTTYKSQI
EQGTVTYLYAFKEVCEKDKLPLKILSYKLAESSNSILFRELREERGLAYDVYSQMDLDENVNTMNIFTSVREESIDEVIE
VIDKAILDIKNKDINFDEDMLCMMKKTHKTGVVSTLEDCSSLCSYVLVQSLAGKDITEFINSMEELETLTGEDIYRVCNK
YLNKPTIHILKPME

Sequences:

>Translated_414_residues
MKRWTFDENTIILPNGLKVITIKKDTRLASINIGVNIGSLYEDEKELGMSHFVEHMLFKGTKNRSNEQLNRELEFLGGDY
NAYTDYISTVYSITCLDEEFEKGIELLSDMVLNSSFDEKEMKKEKGVVLSEIKSDKDDIEDLSISRTHEYAFDKSALKNS
IAGTEEHVKGFKRKQVYDFYKKYYTPDNCVIVTVSAFSHEQMQKIIIDLFGKWEGKSHKKAEIIKEENKELIKTTYKSQI
EQGTVTYLYAFKEVCEKDKLPLKILSYKLAESSNSILFRELREERGLAYDVYSQMDLDENVNTMNIFTSVREESIDEVIE
VIDKAILDIKNKDINFDEDMLCMMKKTHKTGVVSTLEDCSSLCSYVLVQSLAGKDITEFINSMEELETLTGEDIYRVCNK
YLNKPTIHILKPME
>Mature_414_residues
MKRWTFDENTIILPNGLKVITIKKDTRLASINIGVNIGSLYEDEKELGMSHFVEHMLFKGTKNRSNEQLNRELEFLGGDY
NAYTDYISTVYSITCLDEEFEKGIELLSDMVLNSSFDEKEMKKEKGVVLSEIKSDKDDIEDLSISRTHEYAFDKSALKNS
IAGTEEHVKGFKRKQVYDFYKKYYTPDNCVIVTVSAFSHEQMQKIIIDLFGKWEGKSHKKAEIIKEENKELIKTTYKSQI
EQGTVTYLYAFKEVCEKDKLPLKILSYKLAESSNSILFRELREERGLAYDVYSQMDLDENVNTMNIFTSVREESIDEVIE
VIDKAILDIKNKDINFDEDMLCMMKKTHKTGVVSTLEDCSSLCSYVLVQSLAGKDITEFINSMEELETLTGEDIYRVCNK
YLNKPTIHILKPME

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=201, Percent_Identity=32.8358208955224, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI46593007, Length=191, Percent_Identity=30.3664921465969, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI24308013, Length=215, Percent_Identity=25.5813953488372, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI155969707, Length=237, Percent_Identity=27.8481012658228, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1787770, Length=209, Percent_Identity=27.7511961722488, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI2367164, Length=220, Percent_Identity=25.9090909090909, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71999683, Length=417, Percent_Identity=24.7002398081535, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17553678, Length=184, Percent_Identity=26.0869565217391, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI115533970, Length=193, Percent_Identity=32.1243523316062, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323192, Length=200, Percent_Identity=32, Blast_Score=114, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6321813, Length=202, Percent_Identity=23.7623762376238, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21357875, Length=203, Percent_Identity=29.5566502463054, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24646943, Length=203, Percent_Identity=29.5566502463054, Blast_Score=125, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 47874; Mature: 47874

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRWTFDENTIILPNGLKVITIKKDTRLASINIGVNIGSLYEDEKELGMSHFVEHMLFKG
CCCCCCCCCEEECCCCEEEEEEECCCEEEEEEECCEECHHHCCHHHHCHHHHHHHHHHCC
TKNRSNEQLNRELEFLGGDYNAYTDYISTVYSITCLDEEFEKGIELLSDMVLNSSFDEKE
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHH
MKKEKGVVLSEIKSDKDDIEDLSISRTHEYAFDKSALKNSIAGTEEHVKGFKRKQVYDFY
HHHHHCHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
KKYYTPDNCVIVTVSAFSHEQMQKIIIDLFGKWEGKSHKKAEIIKEENKELIKTTYKSQI
HHHCCCCCEEEEEEEHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EQGTVTYLYAFKEVCEKDKLPLKILSYKLAESSNSILFRELREERGLAYDVYSQMDLDEN
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCEEEHHHHCCCCCC
VNTMNIFTSVREESIDEVIEVIDKAILDIKNKDINFDEDMLCMMKKTHKTGVVSTLEDCS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
SLCSYVLVQSLAGKDITEFINSMEELETLTGEDIYRVCNKYLNKPTIHILKPME
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCC
>Mature Secondary Structure
MKRWTFDENTIILPNGLKVITIKKDTRLASINIGVNIGSLYEDEKELGMSHFVEHMLFKG
CCCCCCCCCEEECCCCEEEEEEECCCEEEEEEECCEECHHHCCHHHHCHHHHHHHHHHCC
TKNRSNEQLNRELEFLGGDYNAYTDYISTVYSITCLDEEFEKGIELLSDMVLNSSFDEKE
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHH
MKKEKGVVLSEIKSDKDDIEDLSISRTHEYAFDKSALKNSIAGTEEHVKGFKRKQVYDFY
HHHHHCHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
KKYYTPDNCVIVTVSAFSHEQMQKIIIDLFGKWEGKSHKKAEIIKEENKELIKTTYKSQI
HHHCCCCCEEEEEEEHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EQGTVTYLYAFKEVCEKDKLPLKILSYKLAESSNSILFRELREERGLAYDVYSQMDLDEN
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCEEEHHHHCCCCCC
VNTMNIFTSVREESIDEVIEVIDKAILDIKNKDINFDEDMLCMMKKTHKTGVVSTLEDCS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
SLCSYVLVQSLAGKDITEFINSMEELETLTGEDIYRVCNKYLNKPTIHILKPME
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]