Click here to switch to the map view.

The map label for this gene is hslO

Identifier: 18310883

GI number: 18310883

Start: 2181056

End: 2182015

Strand: Reverse

Name: hslO

Synonym: CPE1901

Alternate gene names: 18310883

Gene position: 2182015-2181056 (Counterclockwise)

Preceding gene: 18310884

Following gene: 18310881

Centisome position: 71.98

GC content: 30.42

Gene sequence:

>960_bases
ATGAGTGATAAATTAATAAGAGCCATAGCTAAAGATGGCATGATAAGAATATTTGCAACAGAAACTACAGAGTTAGTTGA
TGAGGCTTCAAAAATACATGATTGTACACCTACAGCTGCTGCTGCCTTAGGAAGAATGTTAACAGCAGGTACTATGATGG
GAGCAATGTTAAAATCAGATAAAGAAGTTGTAACTTTACAAATAAATGGTGGAGGAATGGCTAAAGGGGTTACTGTAACT
GCTTACTCAGATTGTAGTGTTAAAGGATACATAGGAAATCCACATGTTGATTTACCTTTAAACACAGAAAATGGTAAATT
AAATGTTGGTGAAGCTATTGGTAAAAATGGTGGATTAACAGTAATTAAAGATTTAGGATTAAAAGATCCATATGTAGGAC
AAGTTCCTATATATAGTGGAGAAATAGCTGAGGATTTAGCATATTATTTTACAGCTTCAGAGCAAATACCTTCAGCAGTT
GCCCTAGGAGTATTAGTAGATAGAGATCATTCAATTAAAAAAGCTGGTGGATTTATAATTCAATTATTACCAGGAGCTGA
TGAACTTTTAGGTGACTTATTAACATATAGACTAGATGAGATTCCTTCATTAACTACAATGCTATCAGAAGGAAAAACAA
TAGAAGAAGTTATAGAATTCATTTTTGATGGAATGGATTTAAAAATATTAGAAGAAGAAACTCCAAAATATAAATGTGAT
TGCTCAAGAGAAAAAGTAGAGAGAGCATTATTAAGCATAGGATACAAAGATTTAAAAGAATTATATGATGAAGGTAAAGA
AGAGGAATTAAAATGCCACTTCTGTAATAAAGCATATAAGTTTACAAAAGAAGATATAGGAAAATTATTAGAAGAAAAAG
AAAAATCTATTGCTGATGAAGTTTCAGAAGAAATGAAAAAAGCAGAAGAGAAAGAAAAAGAAGAAAAAAATAAAAAATAA

Upstream 100 bases:

>100_bases
TAAAATAGTAGAAAAGCATAATGGTTATACAGAAGATGAAGTAACACCAGATACTGAAAGAATAGTTTATATAGTAAAAA
AATAACGGAGGGATTAAATT

Downstream 100 bases:

>100_bases
GTTGACAAATTAATTTTAAGTTAATATAATAATAAATGTCTTGAAGAGCTCAAGACATTTGGCTCGATAGCTCAGTCGGT
AGAGCAGAGGACTGAAAATC

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSDKLIRAIAKDGMIRIFATETTELVDEASKIHDCTPTAAAALGRMLTAGTMMGAMLKSDKEVVTLQINGGGMAKGVTVT
AYSDCSVKGYIGNPHVDLPLNTENGKLNVGEAIGKNGGLTVIKDLGLKDPYVGQVPIYSGEIAEDLAYYFTASEQIPSAV
ALGVLVDRDHSIKKAGGFIIQLLPGADELLGDLLTYRLDEIPSLTTMLSEGKTIEEVIEFIFDGMDLKILEEETPKYKCD
CSREKVERALLSIGYKDLKELYDEGKEEELKCHFCNKAYKFTKEDIGKLLEEKEKSIADEVSEEMKKAEEKEKEEKNKK

Sequences:

>Translated_319_residues
MSDKLIRAIAKDGMIRIFATETTELVDEASKIHDCTPTAAAALGRMLTAGTMMGAMLKSDKEVVTLQINGGGMAKGVTVT
AYSDCSVKGYIGNPHVDLPLNTENGKLNVGEAIGKNGGLTVIKDLGLKDPYVGQVPIYSGEIAEDLAYYFTASEQIPSAV
ALGVLVDRDHSIKKAGGFIIQLLPGADELLGDLLTYRLDEIPSLTTMLSEGKTIEEVIEFIFDGMDLKILEEETPKYKCD
CSREKVERALLSIGYKDLKELYDEGKEEELKCHFCNKAYKFTKEDIGKLLEEKEKSIADEVSEEMKKAEEKEKEEKNKK
>Mature_318_residues
SDKLIRAIAKDGMIRIFATETTELVDEASKIHDCTPTAAAALGRMLTAGTMMGAMLKSDKEVVTLQINGGGMAKGVTVTA
YSDCSVKGYIGNPHVDLPLNTENGKLNVGEAIGKNGGLTVIKDLGLKDPYVGQVPIYSGEIAEDLAYYFTASEQIPSAVA
LGVLVDRDHSIKKAGGFIIQLLPGADELLGDLLTYRLDEIPSLTTMLSEGKTIEEVIEFIFDGMDLKILEEETPKYKCDC
SREKVERALLSIGYKDLKELYDEGKEEELKCHFCNKAYKFTKEDIGKLLEEKEKSIADEVSEEMKKAEEKEKEEKNKK

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=291, Percent_Identity=22.3367697594502, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_CLOP1 (Q0TP59)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696581.1
- ProteinModelPortal:   Q0TP59
- SMR:   Q0TP59
- STRING:   Q0TP59
- GeneID:   4201206
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_2157
- TIGR:   CPF_2157
- eggNOG:   COG1281
- HOGENOM:   HBG286231
- OMA:   AYYFTVS
- ProtClustDB:   PRK00114
- BioCyc:   CPER195103:CPF_2157-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 35064; Mature: 34932

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKLIRAIAKDGMIRIFATETTELVDEASKIHDCTPTAAAALGRMLTAGTMMGAMLKSD
CCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
KEVVTLQINGGGMAKGVTVTAYSDCSVKGYIGNPHVDLPLNTENGKLNVGEAIGKNGGLT
CEEEEEEECCCCCCCCEEEEEECCCEEEEECCCCEEEEEECCCCCCEECHHHHCCCCCEE
VIKDLGLKDPYVGQVPIYSGEIAEDLAYYFTASEQIPSAVALGVLVDRDHSIKKAGGFII
EEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCHHHHHHEEECCCCCHHHCCCEEE
QLLPGADELLGDLLTYRLDEIPSLTTMLSEGKTIEEVIEFIFDGMDLKILEEETPKYKCD
EECCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCCCCCCC
CSREKVERALLSIGYKDLKELYDEGKEEELKCHFCNKAYKFTKEDIGKLLEEKEKSIADE
CCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VSEEMKKAEEKEKEEKNKK
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDKLIRAIAKDGMIRIFATETTELVDEASKIHDCTPTAAAALGRMLTAGTMMGAMLKSD
CHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
KEVVTLQINGGGMAKGVTVTAYSDCSVKGYIGNPHVDLPLNTENGKLNVGEAIGKNGGLT
CEEEEEEECCCCCCCCEEEEEECCCEEEEECCCCEEEEEECCCCCCEECHHHHCCCCCEE
VIKDLGLKDPYVGQVPIYSGEIAEDLAYYFTASEQIPSAVALGVLVDRDHSIKKAGGFII
EEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCHHHHHHEEECCCCCHHHCCCEEE
QLLPGADELLGDLLTYRLDEIPSLTTMLSEGKTIEEVIEFIFDGMDLKILEEETPKYKCD
EECCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCCCCCCC
CSREKVERALLSIGYKDLKELYDEGKEEELKCHFCNKAYKFTKEDIGKLLEEKEKSIADE
CCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VSEEMKKAEEKEKEEKNKK
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA