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The map label for this gene is nudE [C]

Identifier: 18310880

GI number: 18310880

Start: 2178625

End: 2179179

Strand: Reverse

Name: nudE [C]

Synonym: CPE1898

Alternate gene names: 18310880

Gene position: 2179179-2178625 (Counterclockwise)

Preceding gene: 18310881

Following gene: 18310877

Centisome position: 71.89

GC content: 28.65

Gene sequence:

>555_bases
ATGAAAATAAAGGATATAAAAAAATTAACTGATTGCAAGTTTTTAAACTTATATAAATTAGATATTGAGAATAAGGTTGG
AAATTCTAAAGAATATTTTATAGCAAGTAGAAGAACAGAAAAAGATTTAAGCTGCGTTGTTAATAAACATGATAAGGCAG
ATGGTGTTATGATAATTCCAATAACAGAAAATGATGAGTTTGTTTTGCTAAAGCAATTTAGACCTGCTATAAATGATTAT
ATATATGAATTCCCAGCTGGACTTATAGACAATGGAGAAGATGCAATAAAGGCTGCTACAAGAGAGCTTTTTGAAGAAAC
TGGACTTTTAGCTAGTGAAAGTGAATATTTAATAAAGCCTAGCTATACGTCAGTAGGTATGTCTGATGAGTCTGTAGCTG
TGGTTAAAATGAAGGTTTATGGAAATATTTCAACAGAAAATTTAGAAGAAAATGAAGAAATAGAAGTTATTAAAGTGCCT
AGAAAAGAGGCTAAAAACTTTGTTAAAGAAAATAATGTATCAATAAAAACTGCATTGGTTTTAAGCTTTATGTAG

Upstream 100 bases:

>100_bases
ATGTGTAAAATTAAAGTAGAATAGTTAAAAATATAGATATATTTTAATTTGTATTAATTTAAAGCTTAATTAAAAGTTAA
AATATGAGAGGAGTATTAAT

Downstream 100 bases:

>100_bases
ATTATAAATAAATTAAAGGAGCTTTATGAAACTTCAAGATAAAATTTATAAATGTGTTAAGAGTTTTTCTTCATACTATT
TATAAACTTTATTAGTGAGT

Product: hypothetical protein

Products: AMP; D-Ribose 5- Phosphate. [C]

Alternate protein names: MutT/NUDIX Family Hydrolase; Nudix-Family Hydrolase; Zn-Finger Containing NTP Pyrophosphohydrolase; Nudix Family Hydrolase; NUDIX Family Hydrolase; ADP-Ribose Pyrophosphatase; NTP Pyrophosphohydrolase; MutT/Nudix Family Protein; NUDIX Domain-Containing Protein; Nucleotide Diphosphate Hydrolase

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MKIKDIKKLTDCKFLNLYKLDIENKVGNSKEYFIASRRTEKDLSCVVNKHDKADGVMIIPITENDEFVLLKQFRPAINDY
IYEFPAGLIDNGEDAIKAATRELFEETGLLASESEYLIKPSYTSVGMSDESVAVVKMKVYGNISTENLEENEEIEVIKVP
RKEAKNFVKENNVSIKTALVLSFM

Sequences:

>Translated_184_residues
MKIKDIKKLTDCKFLNLYKLDIENKVGNSKEYFIASRRTEKDLSCVVNKHDKADGVMIIPITENDEFVLLKQFRPAINDY
IYEFPAGLIDNGEDAIKAATRELFEETGLLASESEYLIKPSYTSVGMSDESVAVVKMKVYGNISTENLEENEEIEVIKVP
RKEAKNFVKENNVSIKTALVLSFM
>Mature_184_residues
MKIKDIKKLTDCKFLNLYKLDIENKVGNSKEYFIASRRTEKDLSCVVNKHDKADGVMIIPITENDEFVLLKQFRPAINDY
IYEFPAGLIDNGEDAIKAATRELFEETGLLASESEYLIKPSYTSVGMSDESVAVVKMKVYGNISTENLEENEEIEVIKVP
RKEAKNFVKENNVSIKTALVLSFM

Specific function: Active On Adenosine(5')Triphospho(5')Adenosine (Ap3a), ADP-Ribose, NADH, Adenosine(5')Diphospho(5')Adenosine (Ap2a). [C]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI37594464, Length=164, Percent_Identity=32.3170731707317, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319587, Length=165, Percent_Identity=32.1212121212121, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.- [C]

Molecular weight: Translated: 20914; Mature: 20914

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKDIKKLTDCKFLNLYKLDIENKVGNSKEYFIASRRTEKDLSCVVNKHDKADGVMIIP
CCCCHHHHHHCCEEEEEEEEEECCCCCCCCEEEEECCCCCCCHHHEECCCCCCCCEEEEE
ITENDEFVLLKQFRPAINDYIYEFPAGLIDNGEDAIKAATRELFEETGLLASESEYLIKP
EECCCCEEEHHHHCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCCEEECC
SYTSVGMSDESVAVVKMKVYGNISTENLEENEEIEVIKVPRKEAKNFVKENNVSIKTALV
CCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCEEEEEEE
LSFM
EECC
>Mature Secondary Structure
MKIKDIKKLTDCKFLNLYKLDIENKVGNSKEYFIASRRTEKDLSCVVNKHDKADGVMIIP
CCCCHHHHHHCCEEEEEEEEEECCCCCCCCEEEEECCCCCCCHHHEECCCCCCCCEEEEE
ITENDEFVLLKQFRPAINDYIYEFPAGLIDNGEDAIKAATRELFEETGLLASESEYLIKP
EECCCCEEEHHHHCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCCEEECC
SYTSVGMSDESVAVVKMKVYGNISTENLEENEEIEVIKVPRKEAKNFVKENNVSIKTALV
CCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCEEEEEEE
LSFM
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ADP-Ribose; H2O [C]

Specific reaction: ADP-Ribose + H2O = AMP + D-Ribose 5- Phosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA