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The map label for this gene is infC

Identifier: 18310876

GI number: 18310876

Start: 2174746

End: 2175150

Strand: Reverse

Name: infC

Synonym: CPE1894

Alternate gene names: 18310876

Gene position: 2175150-2174746 (Counterclockwise)

Preceding gene: 18310877

Following gene: 18310875

Centisome position: 71.75

GC content: 32.59

Gene sequence:

>405_bases
ATGGCAGATGAGGCTGAGTTAGACTTAGTTATGATTTCGCCAAATGCTAAACCACCAGTTTGCAAAATAATGGATTACGG
TAAATTTATTTACGAGCAATCTAAAAAAGAAAAAGAAGCAAAAAAGAAGCAAAAGGTTATCAGTGTTAAGGAGATAAGAG
TTAGCCCAACTATAGAAAAGCATGACTTAGAAATAAAAGCTAAGAATGCTAAAAAATTCTTAGAAGCTGGAGATAAAGTC
AAGATAACTGTAAGATTTAGAGGAAGAGAAGCTGAGCATTCACATGTTGGTGTTAAGATATTAGATAGTTTCTTAGCTCA
ATTAGAGGAAGTATGTTCAGTAGAAAAACCTGCTAAATTAGAAGGTAGAAACATGATAATGATTTTAGCTCCTAAAAAAG
CGTAA

Upstream 100 bases:

>100_bases
AAATTTTGCAATCAATCAAGAAATAAGAGAAAAAGAGGTTAGATTAATTTCTAGCACAGGAGAGCAACTTGGTGTTGTAT
CTGGAAGAGATGCACAAAGA

Downstream 100 bases:

>100_bases
CTTGAGAGGAGGATACTTACAATGCCAAAAATGAAAACTCATAGAGGTGCAGCAAAAAGATTCAAAAAAACAGGAACTGG
AAAGTTAAAGAGAGCTCACG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 134; Mature: 133

Protein sequence:

>134_residues
MADEAELDLVMISPNAKPPVCKIMDYGKFIYEQSKKEKEAKKKQKVISVKEIRVSPTIEKHDLEIKAKNAKKFLEAGDKV
KITVRFRGREAEHSHVGVKILDSFLAQLEEVCSVEKPAKLEGRNMIMILAPKKA

Sequences:

>Translated_134_residues
MADEAELDLVMISPNAKPPVCKIMDYGKFIYEQSKKEKEAKKKQKVISVKEIRVSPTIEKHDLEIKAKNAKKFLEAGDKV
KITVRFRGREAEHSHVGVKILDSFLAQLEEVCSVEKPAKLEGRNMIMILAPKKA
>Mature_133_residues
ADEAELDLVMISPNAKPPVCKIMDYGKFIYEQSKKEKEAKKKQKVISVKEIRVSPTIEKHDLEIKAKNAKKFLEAGDKVK
ITVRFRGREAEHSHVGVKILDSFLAQLEEVCSVEKPAKLEGRNMIMILAPKKA

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=133, Percent_Identity=57.8947368421053, Blast_Score=140, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_CLOPE (Q8XJ67)

Other databases:

- EMBL:   BA000016
- RefSeq:   NP_562810.1
- ProteinModelPortal:   Q8XJ67
- SMR:   Q8XJ67
- GeneID:   990204
- GenomeReviews:   BA000016_GR
- KEGG:   cpe:CPE1894
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- PhylomeDB:   Q8XJ67
- BioCyc:   CPER195102:CPE1894-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 15176; Mature: 15045

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADEAELDLVMISPNAKPPVCKIMDYGKFIYEQSKKEKEAKKKQKVISVKEIRVSPTIEK
CCCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCEEHEEEEECCCCCC
HDLEIKAKNAKKFLEAGDKVKITVRFRGREAEHSHVGVKILDSFLAQLEEVCSVEKPAKL
CCEEEEECHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
EGRNMIMILAPKKA
CCCCEEEEEECCCC
>Mature Secondary Structure 
ADEAELDLVMISPNAKPPVCKIMDYGKFIYEQSKKEKEAKKKQKVISVKEIRVSPTIEK
CCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCEEHEEEEECCCCCC
HDLEIKAKNAKKFLEAGDKVKITVRFRGREAEHSHVGVKILDSFLAQLEEVCSVEKPAKL
CCEEEEECHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
EGRNMIMILAPKKA
CCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842