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The map label for this gene is mraW [H]

Identifier: 18310847

GI number: 18310847

Start: 2135386

End: 2136318

Strand: Reverse

Name: mraW [H]

Synonym: CPE1865

Alternate gene names: 18310847

Gene position: 2136318-2135386 (Counterclockwise)

Preceding gene: 18310848

Following gene: 18310846

Centisome position: 70.47

GC content: 30.55

Gene sequence:

>933_bases
ATGGAATTTAAACACGTTTCGGTTTTGCTAGATGAGTGCATAAATGCTTTAAATATAAAAGAAGATGGTATATATGTAGA
CTGTACATTAGGTGGTGCAGGTCATTCAAGTGAAATAGTAAAAAGACTATCAAGTGATGGTAGATTAATAAGATTCGATC
AAGACAAAGATGCTTTGAAAGCTGCTGGAGAAAGATTGAAAGACTATAAAAATGTTACATATGTTCATAGTAATTTCTAT
GCTATATATGATGTATTAACAGATTTAGGCATAGATGGAGTAGATGGTATCCTTATGGACTTAGGAGTTTCTTCTTATCA
ATTAGATAATGGAGAAAGAGGATTTAGTTATATGCAAGATGCTCCTTTAGATATGAGAATGAATAGAGAAAATGAATTCT
CAGCATATGAAATAGTTAATACATATTCAGAAGAGGAATTATATAGAATAATCAAAGAATATGGAGAAGAAAAATTTGCT
AAAAGAATAGCGAGTTTCATAGTTAAAAATAGAGAAGAGAAAAATATAGAAACTACTTTGGAATTAGTTGAGATAATTAA
AGCCGCAATTCCAGCAAAGGCTAGAAGAGAAGGACCACATCCAGCTAAAAGAACATTCCAAGCTATAAGAATAGAAGTTA
ACAAGGAACTTGAAATTATAAGTAAGACTATTTTAGATGGAGTTAAGAAACTTAATAAAGGTGGAAGAATGGCAATAATA
ACATTCCACTCATTAGAAGATAGAATTGTTAAAAATACATTTAAAGAATTAGCTAATCCATGCACATGTCCAAGTGAGTT
TCCTGTATGTGTTTGCAATAGAAAGCCAGAAGTTAAGCTTATAAGCAGAAAACCTATTGAGGCTAGCAAGGAAGAGCTAG
AATTTAATCCAAGAAGTAGAAGTGCTAAGTTAAGAATAATAGAAAAATTATAA

Upstream 100 bases:

>100_bases
AGCATGATAAATTAAAGCTATTAAGCTATATTATACAGTATATAATATGATTGAGAAAATCAAATGATGATAAGTAATTA
AAAATTTAAGGAGTATTTAT

Downstream 100 bases:

>100_bases
GATGATATATTTAGATAGCTTTATTAGATTTTTAAGTAAGGGGAATAAAAATAATTGGAGAGGGATTGTAGATGATTGTA
AAAGAGTTTGATTATAATGG

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MEFKHVSVLLDECINALNIKEDGIYVDCTLGGAGHSSEIVKRLSSDGRLIRFDQDKDALKAAGERLKDYKNVTYVHSNFY
AIYDVLTDLGIDGVDGILMDLGVSSYQLDNGERGFSYMQDAPLDMRMNRENEFSAYEIVNTYSEEELYRIIKEYGEEKFA
KRIASFIVKNREEKNIETTLELVEIIKAAIPAKARREGPHPAKRTFQAIRIEVNKELEIISKTILDGVKKLNKGGRMAII
TFHSLEDRIVKNTFKELANPCTCPSEFPVCVCNRKPEVKLISRKPIEASKEELEFNPRSRSAKLRIIEKL

Sequences:

>Translated_310_residues
MEFKHVSVLLDECINALNIKEDGIYVDCTLGGAGHSSEIVKRLSSDGRLIRFDQDKDALKAAGERLKDYKNVTYVHSNFY
AIYDVLTDLGIDGVDGILMDLGVSSYQLDNGERGFSYMQDAPLDMRMNRENEFSAYEIVNTYSEEELYRIIKEYGEEKFA
KRIASFIVKNREEKNIETTLELVEIIKAAIPAKARREGPHPAKRTFQAIRIEVNKELEIISKTILDGVKKLNKGGRMAII
TFHSLEDRIVKNTFKELANPCTCPSEFPVCVCNRKPEVKLISRKPIEASKEELEFNPRSRSAKLRIIEKL
>Mature_310_residues
MEFKHVSVLLDECINALNIKEDGIYVDCTLGGAGHSSEIVKRLSSDGRLIRFDQDKDALKAAGERLKDYKNVTYVHSNFY
AIYDVLTDLGIDGVDGILMDLGVSSYQLDNGERGFSYMQDAPLDMRMNRENEFSAYEIVNTYSEEELYRIIKEYGEEKFA
KRIASFIVKNREEKNIETTLELVEIIKAAIPAKARREGPHPAKRTFQAIRIEVNKELEIISKTILDGVKKLNKGGRMAII
TFHSLEDRIVKNTFKELANPCTCPSEFPVCVCNRKPEVKLISRKPIEASKEELEFNPRSRSAKLRIIEKL

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=342, Percent_Identity=34.7953216374269, Blast_Score=169, Evalue=2e-42,
Organism=Homo sapiens, GI165377202, Length=189, Percent_Identity=37.5661375661376, Blast_Score=115, Evalue=4e-26,
Organism=Escherichia coli, GI1786270, Length=313, Percent_Identity=44.0894568690096, Blast_Score=251, Evalue=6e-68,
Organism=Drosophila melanogaster, GI62472493, Length=325, Percent_Identity=34.7692307692308, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI28571637, Length=325, Percent_Identity=34.7692307692308, Blast_Score=145, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 35348; Mature: 35348

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFKHVSVLLDECINALNIKEDGIYVDCTLGGAGHSSEIVKRLSSDGRLIRFDQDKDALK
CCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEECCCHHHHH
AAGERLKDYKNVTYVHSNFYAIYDVLTDLGIDGVDGILMDLGVSSYQLDNGERGFSYMQD
HHHHHHHHHCCEEEEECCHHHHHHHHHHCCCCCCCHHHHHCCCCCEECCCCCCCCHHHHC
APLDMRMNRENEFSAYEIVNTYSEEELYRIIKEYGEEKFAKRIASFIVKNREEKNIETTL
CCCCEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ELVEIIKAAIPAKARREGPHPAKRTFQAIRIEVNKELEIISKTILDGVKKLNKGGRMAII
HHHHHHHHHCCHHHHCCCCCHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHCCCCCEEEE
TFHSLEDRIVKNTFKELANPCTCPSEFPVCVCNRKPEVKLISRKPIEASKEELEFNPRSR
EECCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEECCCCCCCCHHHCCCCCCCC
SAKLRIIEKL
CHHEEEEECC
>Mature Secondary Structure
MEFKHVSVLLDECINALNIKEDGIYVDCTLGGAGHSSEIVKRLSSDGRLIRFDQDKDALK
CCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEECCCHHHHH
AAGERLKDYKNVTYVHSNFYAIYDVLTDLGIDGVDGILMDLGVSSYQLDNGERGFSYMQD
HHHHHHHHHCCEEEEECCHHHHHHHHHHCCCCCCCHHHHHCCCCCEECCCCCCCCHHHHC
APLDMRMNRENEFSAYEIVNTYSEEELYRIIKEYGEEKFAKRIASFIVKNREEKNIETTL
CCCCEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ELVEIIKAAIPAKARREGPHPAKRTFQAIRIEVNKELEIISKTILDGVKKLNKGGRMAII
HHHHHHHHHCCHHHHCCCCCHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHCCCCCEEEE
TFHSLEDRIVKNTFKELANPCTCPSEFPVCVCNRKPEVKLISRKPIEASKEELEFNPRSR
EECCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEECCCCCCCCHHHCCCCCCCC
SAKLRIIEKL
CHHEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA