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The map label for this gene is pyrK [H]

Identifier: 18310782

GI number: 18310782

Start: 2079948

End: 2080928

Strand: Reverse

Name: pyrK [H]

Synonym: CPE1800

Alternate gene names: 18310782

Gene position: 2080928-2079948 (Counterclockwise)

Preceding gene: 18310783

Following gene: 18310781

Centisome position: 68.65

GC content: 30.99

Gene sequence:

>981_bases
ATGGATTATGAAGTAATTGATTGTATAGATGCTGGTACGGAATTTTGTCCTTGTCACTTAGCAGAAGAAGGAGAATGCAT
ACTTTGTTCTCAACTTCACGGAAAGTGTTTTTGTGATTGTGTAAACTGGAAAGGGGTTTGCATATATGAAGAATTTGCAA
GTAATGGATTTAAAGCTAAGGAAGGCAGAAAAACTTTTACTTGTGATGTCATAGATGCTGTAGAAGTTGAAGAAGGATTA
TTATTTATAGAGTTTAGGGCACCTCATAAACTTTGTATTGATTTACTTGGACCAGGTAAGTTTATATTTATAAGGACTAA
TGATAATCCGTTTTTTGATGTACCTATATCTATTTTAGAATCTGATGCAGATAAAAATATAATAAAAGTACTTATTGAAG
TTAGAGGAATAAAAACTAAGAGGCTCTTAAATACTGAGGTCAAAGGAGAAATAACTATAAGAGGGCCTTATTTTAATGGA
GTATTTGGAATAAAAAATATAGACTCAACTAAGAATGGAGAGGTCCTTGTACTTTGCAGAGGAATTGGATTAGCTCCTGC
TGTACCAGTTATTAAAAAATTAGCTAATGAAGGAAATAAGATTAAAATTCTTTTAGATAAGGCACCTTTTAAAGAAAGTT
ATATAGAAAAATATTTAGAGGGATACGATATTCAGTATGTTCCTATGAATTTAATTAATAAAGGTGAAATATCAAATGAA
GCAAAGGAAGTTATTAAAAATGGACAATGGGATTTAATCCATTGTGCTGGAGCGGATATATTAACTTATAAACTTATAGA
ATATTTAAATGATTTGAAAGATGAATCTACAAAAGTATCTTGTTGTAATAATGCTAAAATGTGCTGCGGAGAAGGGGTAT
GTGGAAGCTGTACAGCTAGGTTTGCTGGTCACAAGGTAAAAAGACTTTGTAAGGTGCAAAGTGATCCTAGAAAAATATTT
GAAGATAGAAGATTCATTTAA

Upstream 100 bases:

>100_bases
GAAAATATTTTAAGGATTAATTATTTATTAAAGAAATTTTGTAACATTTTTAATCTCTCAGGGATATTTTAATAGTAAGA
ATTCAAATGGGAGGGTTTTT

Downstream 100 bases:

>100_bases
TAAAGATTAATTTATAGAAGGGAGAGTTTTTATGAAGGTTGTTGTTATTGGTGGCGGATGGTCAGGAGTTGCAGCCGCTA
TTGAAGCAAAAAAAATGGGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MDYEVIDCIDAGTEFCPCHLAEEGECILCSQLHGKCFCDCVNWKGVCIYEEFASNGFKAKEGRKTFTCDVIDAVEVEEGL
LFIEFRAPHKLCIDLLGPGKFIFIRTNDNPFFDVPISILESDADKNIIKVLIEVRGIKTKRLLNTEVKGEITIRGPYFNG
VFGIKNIDSTKNGEVLVLCRGIGLAPAVPVIKKLANEGNKIKILLDKAPFKESYIEKYLEGYDIQYVPMNLINKGEISNE
AKEVIKNGQWDLIHCAGADILTYKLIEYLNDLKDESTKVSCCNNAKMCCGEGVCGSCTARFAGHKVKRLCKVQSDPRKIF
EDRRFI

Sequences:

>Translated_326_residues
MDYEVIDCIDAGTEFCPCHLAEEGECILCSQLHGKCFCDCVNWKGVCIYEEFASNGFKAKEGRKTFTCDVIDAVEVEEGL
LFIEFRAPHKLCIDLLGPGKFIFIRTNDNPFFDVPISILESDADKNIIKVLIEVRGIKTKRLLNTEVKGEITIRGPYFNG
VFGIKNIDSTKNGEVLVLCRGIGLAPAVPVIKKLANEGNKIKILLDKAPFKESYIEKYLEGYDIQYVPMNLINKGEISNE
AKEVIKNGQWDLIHCAGADILTYKLIEYLNDLKDESTKVSCCNNAKMCCGEGVCGSCTARFAGHKVKRLCKVQSDPRKIF
EDRRFI
>Mature_326_residues
MDYEVIDCIDAGTEFCPCHLAEEGECILCSQLHGKCFCDCVNWKGVCIYEEFASNGFKAKEGRKTFTCDVIDAVEVEEGL
LFIEFRAPHKLCIDLLGPGKFIFIRTNDNPFFDVPISILESDADKNIIKVLIEVRGIKTKRLLNTEVKGEITIRGPYFNG
VFGIKNIDSTKNGEVLVLCRGIGLAPAVPVIKKLANEGNKIKILLDKAPFKESYIEKYLEGYDIQYVPMNLINKGEISNE
AKEVIKNGQWDLIHCAGADILTYKLIEYLNDLKDESTKVSCCNNAKMCCGEGVCGSCTARFAGHKVKRLCKVQSDPRKIF
EDRRFI

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 36551; Mature: 36551

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00197 2FE2S_FER_1 ; PS00200 RIESKE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
6.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYEVIDCIDAGTEFCPCHLAEEGECILCSQLHGKCFCDCVNWKGVCIYEEFASNGFKAK
CCCEEEEHHHCCCCCCCEECCCCCCEEEEECCCCCEEEEEECCCCEEEEHHHHCCCCCCC
EGRKTFTCDVIDAVEVEEGLLFIEFRAPHKLCIDLLGPGKFIFIRTNDNPFFDVPISILE
CCCCEEEEEEEEEEECCCCEEEEEECCCHHEEHEEECCCEEEEEEECCCCEEECCHHEEC
SDADKNIIKVLIEVRGIKTKRLLNTEVKGEITIRGPYFNGVFGIKNIDSTKNGEVLVLCR
CCCCHHHHHHHHHHCCCCHHHHCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCEEEEEE
GIGLAPAVPVIKKLANEGNKIKILLDKAPFKESYIEKYLEGYDIQYVPMNLINKGEISNE
CCCCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCHH
AKEVIKNGQWDLIHCAGADILTYKLIEYLNDLKDESTKVSCCNNAKMCCGEGVCGSCTAR
HHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHH
FAGHKVKRLCKVQSDPRKIFEDRRFI
HHHHHHHHHHHCCCCHHHHHHCCCCC
>Mature Secondary Structure
MDYEVIDCIDAGTEFCPCHLAEEGECILCSQLHGKCFCDCVNWKGVCIYEEFASNGFKAK
CCCEEEEHHHCCCCCCCEECCCCCCEEEEECCCCCEEEEEECCCCEEEEHHHHCCCCCCC
EGRKTFTCDVIDAVEVEEGLLFIEFRAPHKLCIDLLGPGKFIFIRTNDNPFFDVPISILE
CCCCEEEEEEEEEEECCCCEEEEEECCCHHEEHEEECCCEEEEEEECCCCEEECCHHEEC
SDADKNIIKVLIEVRGIKTKRLLNTEVKGEITIRGPYFNGVFGIKNIDSTKNGEVLVLCR
CCCCHHHHHHHHHHCCCCHHHHCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCEEEEEE
GIGLAPAVPVIKKLANEGNKIKILLDKAPFKESYIEKYLEGYDIQYVPMNLINKGEISNE
CCCCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCHH
AKEVIKNGQWDLIHCAGADILTYKLIEYLNDLKDESTKVSCCNNAKMCCGEGVCGSCTAR
HHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHH
FAGHKVKRLCKVQSDPRKIFEDRRFI
HHHHHHHHHHHCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]