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The map label for this gene is fur [H]

Identifier: 18310758

GI number: 18310758

Start: 2056051

End: 2056503

Strand: Reverse

Name: fur [H]

Synonym: CPE1776

Alternate gene names: 18310758

Gene position: 2056503-2056051 (Counterclockwise)

Preceding gene: 18310759

Following gene: 18310757

Centisome position: 67.84

GC content: 32.45

Gene sequence:

>453_bases
ATGGCAAATACAGCTTCAGTAGATTTTGATGCTTTAAAAGAAGAATTAAAGAAGAAGGGTTATAAGTTAACACCTCAGAG
AAGAGCTATAGTTGATACTATAATACAAAATGAGGGTAAACACTTAACTGCTGAGGAAATTTATGACGAGGTTAAGAAAA
GTTGTCCAGAGATTGGATTAGCTACCGTATATAGAACAATAATTCTTCTAGAAGAGATGGGTGTAATCTATAAGTTAGAT
TTAGAAGATGGATGCAGTAGATATGAACTTGCTCATGACGATGAAGAGCATAGACACCATCATCTAGTTTGTAATAAATG
TGGAAAAGTTTTTGAGGTTGAAGCGGATTTATTAGACGAACTAGAAGAAGAGATTGAAACTAAATATGGCTTTGAAATAT
TAGATCATACAGTAAAGTTTTTCGGAATATGCAAGGATTGTAAAAATGAATAG

Upstream 100 bases:

>100_bases
CTTTAGCTCCAGTTGAGAATGATTTTGAAATTGAAATGATAGAAGAAGCTTATGCAACTTTATTCGCAGAAGAAGAATAA
CGGTAAAGTGAGGTTTTAAT

Downstream 100 bases:

>100_bases
AGAAATTTTCTCAAATGAGGAAACCTCTTTTATACATAAGCGTACTACTACAAAAAAGAGGAGGGAAAATATGAAACGTG
AAAAGCTAAAGGTTAAAATT

Product: FUR family transcriptional regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MANTASVDFDALKEELKKKGYKLTPQRRAIVDTIIQNEGKHLTAEEIYDEVKKSCPEIGLATVYRTIILLEEMGVIYKLD
LEDGCSRYELAHDDEEHRHHHLVCNKCGKVFEVEADLLDELEEEIETKYGFEILDHTVKFFGICKDCKNE

Sequences:

>Translated_150_residues
MANTASVDFDALKEELKKKGYKLTPQRRAIVDTIIQNEGKHLTAEEIYDEVKKSCPEIGLATVYRTIILLEEMGVIYKLD
LEDGCSRYELAHDDEEHRHHHLVCNKCGKVFEVEADLLDELEEEIETKYGFEILDHTVKFFGICKDCKNE
>Mature_149_residues
ANTASVDFDALKEELKKKGYKLTPQRRAIVDTIIQNEGKHLTAEEIYDEVKKSCPEIGLATVYRTIILLEEMGVIYKLDL
EDGCSRYELAHDDEEHRHHHLVCNKCGKVFEVEADLLDELEEEIETKYGFEILDHTVKFFGICKDCKNE

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=135, Percent_Identity=34.8148148148148, Blast_Score=91, Evalue=3e-20,
Organism=Escherichia coli, GI87082363, Length=150, Percent_Identity=25.3333333333333, Blast_Score=60, Evalue=4e-11,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17336; Mature: 17205

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTASVDFDALKEELKKKGYKLTPQRRAIVDTIIQNEGKHLTAEEIYDEVKKSCPEIGL
CCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHH
ATVYRTIILLEEMGVIYKLDLEDGCSRYELAHDDEEHRHHHLVCNKCGKVFEVEADLLDE
HHHHHHHHHHHHCCCEEEEECCCCCCHHCCCCCCHHHHHHHHHHHHCCCEEECHHHHHHH
LEEEIETKYGFEILDHTVKFFGICKDCKNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANTASVDFDALKEELKKKGYKLTPQRRAIVDTIIQNEGKHLTAEEIYDEVKKSCPEIGL
CCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHH
ATVYRTIILLEEMGVIYKLDLEDGCSRYELAHDDEEHRHHHLVCNKCGKVFEVEADLLDE
HHHHHHHHHHHHCCCEEEEECCCCCCHHCCCCCCHHHHHHHHHHHHCCCEEECHHHHHHH
LEEEIETKYGFEILDHTVKFFGICKDCKNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]