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The map label for this gene is typA [H]

Identifier: 18310756

GI number: 18310756

Start: 2052324

End: 2054156

Strand: Reverse

Name: typA [H]

Synonym: CPE1774

Alternate gene names: 18310756

Gene position: 2054156-2052324 (Counterclockwise)

Preceding gene: 18310757

Following gene: 18310755

Centisome position: 67.76

GC content: 32.19

Gene sequence:

>1833_bases
ATGAGTAACGAATTTACAAGAAATGATATTAGAAATATAGCTATAATCGCTCACGTTGACCATGGTAAAACAACTTTAGT
TGACGCATTATTAAGACAAAGTAACGTTTTTAGAACAAACGAAAAAGTAGAAGAGAGAGTAATGGACTCAAATGACTTAG
AAAAAGAAAGAGGTATTACAATACTTTCAAAAAATACAGCAGTTCATTATAACGGAGTTAAAATAAATATAATAGATACA
CCAGGACACGCTGACTTCGGAGGAGAGGTTGAACGTGTACTTAAAATGGTAGAAAGTGTTTTACTTGTAGTAGACTCATA
TGAAGGGGCTATGCCTCAAACAAAATTCGTTTTAAGAAAAGCTCTTGAGTTAGGATTAAAACCAATAGTTGTTATAAACA
AAATAGATAAACCAGATGCTAGACCAGAAGAAGTTATTGATGAAATATTTGAATTATTCTTAGAGCTTGGTGCAGATGAT
GAGCAATTAGATTTCCCAATAGTTTATGCTTCAGCTAGAGATGGAGTAGCTACAATTAACATAGATGAGCCAAAAGATAA
CATGAAAGATTTATTCGATACTATAATCGAAAAAGTTGAATCACCAAAGGGATCTATAGAAGAAAGTTTACAAATGTTAG
TTACAACTTTAGATTCAAGTGAATATGTTGGTAAAATAGCTATAGGTAAAATAACTAGAGGAATAGCTAAGAAAAACCAA
CAAGCTGCTGTTGTAAGACAAGATGGAACAGTAACTAAATTCAAAATATCAAGTCTTTATACTCATGATGGATTAAAGAG
AATAGAGGTTGATGAAGCTCAATTAGGAGATATAGTTGCAATAAGCGGTATATCTGACGTAAATATTGGAGAAACTATAA
CAGATGCACAAAATCCAGAAGGATTACCATTTGTTAAAATAGACGAGCCTACATTAAACATGAACTTTATGGTTAATGAC
TCACCATTTGCTGGTAGAGAAGGGGATTTCGTAACTTCAAGACATTTAAGAGATAGATTATTAAAAGAATTAGAAACTAA
CGTAAGTTTAAAAGTTAAAGAAATAACTCCAGATTGTTTCGAAGTAAGTGGTAGAGGAGAGTTACATCTTTCAATACTTA
TAGAAACAATGAGAAGAGAAGGATATGAATTCCAAGTTTCTAAGCCAAACGTTATAACAAAAATAGATGAAAATGGTGTT
AAGGTTGAACCAATAGAGCACTTAACTATAGACGTTCCAGAAGAATTTATGGGACCTGTTATGGAAAAATTAGGACCTAG
AAAAGCTGAAATGGTAAATATGACTTCAGCGGTTAATGGATACTCAAGATTAGAGTTCAAAATACCTGCAAGAGGACTTA
TAGGATTTAGAAATGAATTCATGACAGATACAAAAGGTAACGGAATAATGAACCATGTATTTGATGGATTTGAAAAATAC
AAAGGAGAGATCCCAGGAAGAAGTAGAGGATCAATCGTAGTATTTGAATCAGGAGAAGCAGTTACATATGGATTATTTAA
TGCTCAAGAAAGAGGAACTTTATTCATAGAGCCAGGTACAGAAGTTTATGCTGGAATGGTTTGTGGAGAATGTTCAAGAG
CAGATGACATAGACGTTAATATTTGTAAGAAAAAACAATTAACTAATACAAGATCATCTGGAGCTGATGATGCTTTAAAA
TTAACTCCAGTAAGACAAATGTCATTAGAGCAATGTTTAGAATTCATAAACAATGACGAATTAGTTGAAGTTACTCCAGT
AAATGTAAGAATGAGAAAGAGAATCTTAGACAGTGCTGAGAGAAAGAGAGCTATAAATAGAAGTAAAAAATAA

Upstream 100 bases:

>100_bases
TTTTTTAAAGCTTAACAGTAGAATCTAATAAGGTAAAGAAAATTGGGTACTTAAATAGTATCCAATTTTTTATGCACATA
AAATTGGAGGAATAAATATA

Downstream 100 bases:

>100_bases
TAAATTTTCTTATAATTTTATTTTATAACTTTGGGTACATAAACAAAAATTAGTAAAACAAGTTTGTTTTTATGAGAAAA
AGATTTATAATTAGATAAAT

Product: GTP-binding protein TypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 610; Mature: 609

Protein sequence:

>610_residues
MSNEFTRNDIRNIAIIAHVDHGKTTLVDALLRQSNVFRTNEKVEERVMDSNDLEKERGITILSKNTAVHYNGVKINIIDT
PGHADFGGEVERVLKMVESVLLVVDSYEGAMPQTKFVLRKALELGLKPIVVINKIDKPDARPEEVIDEIFELFLELGADD
EQLDFPIVYASARDGVATINIDEPKDNMKDLFDTIIEKVESPKGSIEESLQMLVTTLDSSEYVGKIAIGKITRGIAKKNQ
QAAVVRQDGTVTKFKISSLYTHDGLKRIEVDEAQLGDIVAISGISDVNIGETITDAQNPEGLPFVKIDEPTLNMNFMVND
SPFAGREGDFVTSRHLRDRLLKELETNVSLKVKEITPDCFEVSGRGELHLSILIETMRREGYEFQVSKPNVITKIDENGV
KVEPIEHLTIDVPEEFMGPVMEKLGPRKAEMVNMTSAVNGYSRLEFKIPARGLIGFRNEFMTDTKGNGIMNHVFDGFEKY
KGEIPGRSRGSIVVFESGEAVTYGLFNAQERGTLFIEPGTEVYAGMVCGECSRADDIDVNICKKKQLTNTRSSGADDALK
LTPVRQMSLEQCLEFINNDELVEVTPVNVRMRKRILDSAERKRAINRSKK

Sequences:

>Translated_610_residues
MSNEFTRNDIRNIAIIAHVDHGKTTLVDALLRQSNVFRTNEKVEERVMDSNDLEKERGITILSKNTAVHYNGVKINIIDT
PGHADFGGEVERVLKMVESVLLVVDSYEGAMPQTKFVLRKALELGLKPIVVINKIDKPDARPEEVIDEIFELFLELGADD
EQLDFPIVYASARDGVATINIDEPKDNMKDLFDTIIEKVESPKGSIEESLQMLVTTLDSSEYVGKIAIGKITRGIAKKNQ
QAAVVRQDGTVTKFKISSLYTHDGLKRIEVDEAQLGDIVAISGISDVNIGETITDAQNPEGLPFVKIDEPTLNMNFMVND
SPFAGREGDFVTSRHLRDRLLKELETNVSLKVKEITPDCFEVSGRGELHLSILIETMRREGYEFQVSKPNVITKIDENGV
KVEPIEHLTIDVPEEFMGPVMEKLGPRKAEMVNMTSAVNGYSRLEFKIPARGLIGFRNEFMTDTKGNGIMNHVFDGFEKY
KGEIPGRSRGSIVVFESGEAVTYGLFNAQERGTLFIEPGTEVYAGMVCGECSRADDIDVNICKKKQLTNTRSSGADDALK
LTPVRQMSLEQCLEFINNDELVEVTPVNVRMRKRILDSAERKRAINRSKK
>Mature_609_residues
SNEFTRNDIRNIAIIAHVDHGKTTLVDALLRQSNVFRTNEKVEERVMDSNDLEKERGITILSKNTAVHYNGVKINIIDTP
GHADFGGEVERVLKMVESVLLVVDSYEGAMPQTKFVLRKALELGLKPIVVINKIDKPDARPEEVIDEIFELFLELGADDE
QLDFPIVYASARDGVATINIDEPKDNMKDLFDTIIEKVESPKGSIEESLQMLVTTLDSSEYVGKIAIGKITRGIAKKNQQ
AAVVRQDGTVTKFKISSLYTHDGLKRIEVDEAQLGDIVAISGISDVNIGETITDAQNPEGLPFVKIDEPTLNMNFMVNDS
PFAGREGDFVTSRHLRDRLLKELETNVSLKVKEITPDCFEVSGRGELHLSILIETMRREGYEFQVSKPNVITKIDENGVK
VEPIEHLTIDVPEEFMGPVMEKLGPRKAEMVNMTSAVNGYSRLEFKIPARGLIGFRNEFMTDTKGNGIMNHVFDGFEKYK
GEIPGRSRGSIVVFESGEAVTYGLFNAQERGTLFIEPGTEVYAGMVCGECSRADDIDVNICKKKQLTNTRSSGADDALKL
TPVRQMSLEQCLEFINNDELVEVTPVNVRMRKRILDSAERKRAINRSKK

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=470, Percent_Identity=28.7234042553192, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI94966754, Length=133, Percent_Identity=43.609022556391, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI4503483, Length=147, Percent_Identity=37.4149659863946, Blast_Score=106, Evalue=7e-23,
Organism=Homo sapiens, GI18390331, Length=145, Percent_Identity=39.3103448275862, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI25306283, Length=176, Percent_Identity=36.3636363636364, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI19923640, Length=176, Percent_Identity=36.3636363636364, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI25306287, Length=176, Percent_Identity=36.3636363636364, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI310132016, Length=111, Percent_Identity=39.6396396396396, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI310110807, Length=111, Percent_Identity=39.6396396396396, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI310123363, Length=111, Percent_Identity=39.6396396396396, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI34147630, Length=276, Percent_Identity=27.1739130434783, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI217272894, Length=135, Percent_Identity=34.8148148148148, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI217272892, Length=135, Percent_Identity=34.8148148148148, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI94966752, Length=129, Percent_Identity=32.5581395348837, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI53729339, Length=163, Percent_Identity=32.5153374233129, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI53729337, Length=163, Percent_Identity=32.5153374233129, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI48994988, Length=603, Percent_Identity=53.7313432835821, Blast_Score=648, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=501, Percent_Identity=28.3433133732535, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI1789738, Length=151, Percent_Identity=37.7483443708609, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1790835, Length=180, Percent_Identity=32.2222222222222, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789559, Length=191, Percent_Identity=30.3664921465969, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1789737, Length=238, Percent_Identity=27.7310924369748, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790412, Length=238, Percent_Identity=27.3109243697479, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17557151, Length=292, Percent_Identity=30.4794520547945, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17556745, Length=142, Percent_Identity=40.1408450704225, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17506493, Length=177, Percent_Identity=34.4632768361582, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71988811, Length=128, Percent_Identity=41.40625, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71988819, Length=128, Percent_Identity=41.40625, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17533571, Length=143, Percent_Identity=40.5594405594406, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17556456, Length=285, Percent_Identity=30.8771929824561, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17552882, Length=134, Percent_Identity=35.0746268656716, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI25141371, Length=244, Percent_Identity=27.0491803278689, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71994658, Length=151, Percent_Identity=32.4503311258278, Blast_Score=67, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323320, Length=483, Percent_Identity=27.7432712215321, Blast_Score=130, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6324707, Length=146, Percent_Identity=40.4109589041096, Blast_Score=114, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6320593, Length=146, Percent_Identity=40.4109589041096, Blast_Score=114, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6323098, Length=226, Percent_Identity=34.5132743362832, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324761, Length=270, Percent_Identity=28.8888888888889, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324166, Length=180, Percent_Identity=33.8888888888889, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322359, Length=149, Percent_Identity=35.5704697986577, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6324550, Length=255, Percent_Identity=29.8039215686275, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI78706572, Length=237, Percent_Identity=31.6455696202532, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24585711, Length=167, Percent_Identity=34.1317365269461, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24585713, Length=167, Percent_Identity=34.1317365269461, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24585709, Length=167, Percent_Identity=34.1317365269461, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI28574573, Length=140, Percent_Identity=40, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24582462, Length=147, Percent_Identity=40.1360544217687, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21357743, Length=171, Percent_Identity=35.0877192982456, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281363316, Length=239, Percent_Identity=30.1255230125523, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI17864358, Length=239, Percent_Identity=30.1255230125523, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI221458488, Length=186, Percent_Identity=35.4838709677419, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI19921738, Length=233, Percent_Identity=27.4678111587983, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28572034, Length=279, Percent_Identity=27.5985663082437, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 68163; Mature: 68032

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNEFTRNDIRNIAIIAHVDHGKTTLVDALLRQSNVFRTNEKVEERVMDSNDLEKERGIT
CCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHCCEE
ILSKNTAVHYNGVKINIIDTPGHADFGGEVERVLKMVESVLLVVDSYEGAMPQTKFVLRK
EEECCCEEEECCEEEEEEECCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHH
ALELGLKPIVVINKIDKPDARPEEVIDEIFELFLELGADDEQLDFPIVYASARDGVATIN
HHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEE
IDEPKDNMKDLFDTIIEKVESPKGSIEESLQMLVTTLDSSEYVGKIAIGKITRGIAKKNQ
ECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHCEEEHHHHHHHHHHCCC
QAAVVRQDGTVTKFKISSLYTHDGLKRIEVDEAQLGDIVAISGISDVNIGETITDAQNPE
CEEEEECCCCEEEEEEEEEHHCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCC
GLPFVKIDEPTLNMNFMVNDSPFAGREGDFVTSRHLRDRLLKELETNVSLKVKEITPDCF
CCEEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHH
EVSGRGELHLSILIETMRREGYEFQVSKPNVITKIDENGVKVEPIEHLTIDVPEEFMGPV
EECCCCCEEHHHHHHHHHHCCCEEEECCCCEEEEECCCCCEECCCCEEEEECCHHHHHHH
MEKLGPRKAEMVNMTSAVNGYSRLEFKIPARGLIGFRNEFMTDTKGNGIMNHVFDGFEKY
HHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
KGEIPGRSRGSIVVFESGEAVTYGLFNAQERGTLFIEPGTEVYAGMVCGECSRADDIDVN
CCCCCCCCCCCEEEEECCCEEEEEEECCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCEE
ICKKKQLTNTRSSGADDALKLTPVRQMSLEQCLEFINNDELVEVTPVNVRMRKRILDSAE
EECCHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHH
RKRAINRSKK
HHHHHHCCCC
>Mature Secondary Structure 
SNEFTRNDIRNIAIIAHVDHGKTTLVDALLRQSNVFRTNEKVEERVMDSNDLEKERGIT
CCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHCCEE
ILSKNTAVHYNGVKINIIDTPGHADFGGEVERVLKMVESVLLVVDSYEGAMPQTKFVLRK
EEECCCEEEECCEEEEEEECCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHH
ALELGLKPIVVINKIDKPDARPEEVIDEIFELFLELGADDEQLDFPIVYASARDGVATIN
HHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEE
IDEPKDNMKDLFDTIIEKVESPKGSIEESLQMLVTTLDSSEYVGKIAIGKITRGIAKKNQ
ECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHCEEEHHHHHHHHHHCCC
QAAVVRQDGTVTKFKISSLYTHDGLKRIEVDEAQLGDIVAISGISDVNIGETITDAQNPE
CEEEEECCCCEEEEEEEEEHHCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCC
GLPFVKIDEPTLNMNFMVNDSPFAGREGDFVTSRHLRDRLLKELETNVSLKVKEITPDCF
CCEEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHH
EVSGRGELHLSILIETMRREGYEFQVSKPNVITKIDENGVKVEPIEHLTIDVPEEFMGPV
EECCCCCEEHHHHHHHHHHCCCEEEECCCCEEEEECCCCCEECCCCEEEEECCHHHHHHH
MEKLGPRKAEMVNMTSAVNGYSRLEFKIPARGLIGFRNEFMTDTKGNGIMNHVFDGFEKY
HHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
KGEIPGRSRGSIVVFESGEAVTYGLFNAQERGTLFIEPGTEVYAGMVCGECSRADDIDVN
CCCCCCCCCCCEEEEECCCEEEEEEECCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCEE
ICKKKQLTNTRSSGADDALKLTPVRQMSLEQCLEFINNDELVEVTPVNVRMRKRILDSAE
EECCHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHH
RKRAINRSKK
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]