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The map label for this gene is udk

Identifier: 18310752

GI number: 18310752

Start: 2048632

End: 2049258

Strand: Reverse

Name: udk

Synonym: CPE1770

Alternate gene names: 18310752

Gene position: 2049258-2048632 (Counterclockwise)

Preceding gene: 18310753

Following gene: 18310751

Centisome position: 67.6

GC content: 29.82

Gene sequence:

>627_bases
ATGAAGAGACCAATTTTTATAGGAATAACAGGAGGCACTGGCTCAGGTAAAAGTACAATAGCTAAGGAGATATATAGACA
ATTTGGTGAAGATTGTATAGCAATGATAGAGCAAGATTCATATTATAAGGATCAAAGCCATTTATCAATGGAGGATAGAG
TTAAAACTAACTACGATCATCCAAATGCTTTTGATAACAATCTTTTAGTTTCACATTTAGAATCACTTTTAAATGGACAT
TCTATACAAAAACCTAGTTATGACTTCTCTATACATAATAGAATTGAAGATACAACTAAGGTTGAGCCAAAAGAAATTGT
TATTGTAGAAGGAATATTAATACTAGAAGATCCAAGAATAAGAGAACTTCTAGATATAAAGATTTACGTTGATACAGATG
CTGATGTTAGAATCATAAGAAGAATGGTCAGAGACATAAATGAAAGAGGAAGAACTATGGAGTCTGTTATAAATCAGTAC
TTAAATGTAGTAAAGCCTATGCATAATCAATTTACAGAACCTACAAAGAAATTTGCTGATATAATAATACCAGAAGGTGG
ACATAATAAAGTTGCTATAGATATTATTGTTGCAAAAATAAAAGAGGTTTTAGGAAAATACGAATAA

Upstream 100 bases:

>100_bases
TAGATGTTGCTAACAAAGCTCAAATGATATTCAAGGTTAAAATAGATAAGCCTGTAAAGGTAAATGATATGTTAATTAAG
TGCAAGGAGGCAAACAGCTA

Downstream 100 bases:

>100_bases
TATCTTAAAAAGGTATATTACGATTTTACTTAAATAAGAGATAGAAGTAATTATTTCTTATTGAATAAAACACCCCTAAC
TTGGCTAGAATTTAGCCAGG

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKRPIFIGITGGTGSGKSTIAKEIYRQFGEDCIAMIEQDSYYKDQSHLSMEDRVKTNYDHPNAFDNNLLVSHLESLLNGH
SIQKPSYDFSIHNRIEDTTKVEPKEIVIVEGILILEDPRIRELLDIKIYVDTDADVRIIRRMVRDINERGRTMESVINQY
LNVVKPMHNQFTEPTKKFADIIIPEGGHNKVAIDIIVAKIKEVLGKYE

Sequences:

>Translated_208_residues
MKRPIFIGITGGTGSGKSTIAKEIYRQFGEDCIAMIEQDSYYKDQSHLSMEDRVKTNYDHPNAFDNNLLVSHLESLLNGH
SIQKPSYDFSIHNRIEDTTKVEPKEIVIVEGILILEDPRIRELLDIKIYVDTDADVRIIRRMVRDINERGRTMESVINQY
LNVVKPMHNQFTEPTKKFADIIIPEGGHNKVAIDIIVAKIKEVLGKYE
>Mature_208_residues
MKRPIFIGITGGTGSGKSTIAKEIYRQFGEDCIAMIEQDSYYKDQSHLSMEDRVKTNYDHPNAFDNNLLVSHLESLLNGH
SIQKPSYDFSIHNRIEDTTKVEPKEIVIVEGILILEDPRIRELLDIKIYVDTDADVRIIRRMVRDINERGRTMESVINQY
LNVVKPMHNQFTEPTKKFADIIIPEGGHNKVAIDIIVAKIKEVLGKYE

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family

Homologues:

Organism=Homo sapiens, GI18699734, Length=213, Percent_Identity=42.2535211267606, Blast_Score=189, Evalue=1e-48,
Organism=Homo sapiens, GI13899253, Length=215, Percent_Identity=40.9302325581395, Blast_Score=182, Evalue=2e-46,
Organism=Homo sapiens, GI57863312, Length=209, Percent_Identity=41.6267942583732, Blast_Score=178, Evalue=3e-45,
Organism=Homo sapiens, GI301129207, Length=209, Percent_Identity=41.6267942583732, Blast_Score=178, Evalue=3e-45,
Organism=Homo sapiens, GI209863022, Length=184, Percent_Identity=34.2391304347826, Blast_Score=124, Evalue=6e-29,
Organism=Escherichia coli, GI87082034, Length=204, Percent_Identity=52.4509803921569, Blast_Score=232, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17539894, Length=206, Percent_Identity=39.3203883495146, Blast_Score=172, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI17539892, Length=206, Percent_Identity=39.3203883495146, Blast_Score=172, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI71981181, Length=219, Percent_Identity=36.0730593607306, Blast_Score=149, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6324339, Length=194, Percent_Identity=36.0824742268041, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6320223, Length=215, Percent_Identity=26.5116279069767, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24649624, Length=218, Percent_Identity=44.0366972477064, Blast_Score=197, Evalue=5e-51,
Organism=Drosophila melanogaster, GI221458995, Length=217, Percent_Identity=43.778801843318, Blast_Score=195, Evalue=2e-50,
Organism=Drosophila melanogaster, GI45550449, Length=203, Percent_Identity=41.3793103448276, Blast_Score=170, Evalue=7e-43,
Organism=Drosophila melanogaster, GI28573516, Length=203, Percent_Identity=41.3793103448276, Blast_Score=170, Evalue=7e-43,
Organism=Drosophila melanogaster, GI28573514, Length=203, Percent_Identity=41.3793103448276, Blast_Score=170, Evalue=7e-43,
Organism=Drosophila melanogaster, GI28573512, Length=203, Percent_Identity=41.3793103448276, Blast_Score=170, Evalue=7e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URK_CLOP1 (Q0TPI4)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696456.1
- ProteinModelPortal:   Q0TPI4
- STRING:   Q0TPI4
- GeneID:   4203237
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_2023
- TIGR:   CPF_2023
- eggNOG:   COG0572
- HOGENOM:   HBG527126
- OMA:   NQFVEPT
- ProtClustDB:   PRK05480
- BioCyc:   CPER195103:CPF_2023-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00551
- InterPro:   IPR006083
- InterPro:   IPR000764
- PANTHER:   PTHR10285:SF6
- PRINTS:   PR00988
- TIGRFAMs:   TIGR00235

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.48

Molecular weight: Translated: 23885; Mature: 23885

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRPIFIGITGGTGSGKSTIAKEIYRQFGEDCIAMIEQDSYYKDQSHLSMEDRVKTNYDH
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHHHCCCCC
PNAFDNNLLVSHLESLLNGHSIQKPSYDFSIHNRIEDTTKVEPKEIVIVEGILILEDPRI
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCEEEEEECEEEECCCCH
RELLDIKIYVDTDADVRIIRRMVRDINERGRTMESVINQYLNVVKPMHNQFTEPTKKFAD
HEEEEEEEEEECCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IIIPEGGHNKVAIDIIVAKIKEVLGKYE
EECCCCCCCEEEHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRPIFIGITGGTGSGKSTIAKEIYRQFGEDCIAMIEQDSYYKDQSHLSMEDRVKTNYDH
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHHHCCCCC
PNAFDNNLLVSHLESLLNGHSIQKPSYDFSIHNRIEDTTKVEPKEIVIVEGILILEDPRI
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCEEEEEECEEEECCCCH
RELLDIKIYVDTDADVRIIRRMVRDINERGRTMESVINQYLNVVKPMHNQFTEPTKKFAD
HEEEEEEEEEECCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IIIPEGGHNKVAIDIIVAKIKEVLGKYE
EECCCCCCCEEEHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA