Click here to switch to the map view.

The map label for this gene is gpsA

Identifier: 18310736

GI number: 18310736

Start: 2032094

End: 2033089

Strand: Reverse

Name: gpsA

Synonym: CPE1754

Alternate gene names: 18310736

Gene position: 2033089-2032094 (Counterclockwise)

Preceding gene: 18310737

Following gene: 18310735

Centisome position: 67.07

GC content: 33.13

Gene sequence:

>996_bases
ATGAGTAAAGTGGCTTTTTTAGGAGCAGGAAGTTTTGGAACTTCTTTAGGTATATTATTGGGGAATAAAGGTGTTACGGT
TTCTCTGTGGGATAGAGATGAAAATGTAATAAATGACATTAACGTAAACAGAAAGAATGACAAATATATAAAAGATTTAA
CTATTCCTACTAATGTCACTGCTTATAAAGACTTAGATGAAGCTTTAAATGGGGCTGAATATGTAGTTCTTGCAGTACCT
TCTCATGTTATAAGAACAGCTTGTAAAAACCTAAAGGGTAAAATTAATGATGATGTAATAATTATTAATATTGCTAAAGG
AATAGAAGAGGGTACTAATTTGAGACTATCTCAAGTTATAAATCAAGAATTACCAAATAATAAGGTCGTAGTTTTATCTG
GGCCAAGTCATGCAGAAGAGGTTTCAAAAGGAATTCCAACAACTTTAGTTGCAAGTTCAGAATGTATGGAATGTGCAGAG
AAAGTTCAAGACCTATTTATGGATAAAAACTTTAGAATATATACTAATGATGATATCATAGGTGTTGAAATTGGAGGAGC
CGTTAAAAACATTATAGCCTTAGCGGCAGGTGTTTGTGACGGTATAGGATATGGAGACAATTCTAAGGCCGCATTAATGA
CTAGAGGAATGGCTGAAATAGCTAGAATAGGAATTAAAATGGGTGGAAAAGCTGAAACTTTCTTTGGATTAACTGGTATG
GGAGATTTAATAGTTACTTGTACAAGTATGCATTCAAGAAACAGAAGAGCTGGAATACTTATAGGTCAAGGAAAAACTGC
TGAAGAAGCTATAGAAGAAGTAGGAATGGTTGTTGAAGGTATAAAAGCTTGTAAAGCCTTCTATGAGTTAAAAGAAAAAG
AAGGAGTAACAATGCCTATAACTGATATAGCATACAAAGTTCTTTTTGAAGGGGCAAAGGCAGAAAATGCTGTAAGCCTT
TTAATGGAAAGAGATAAGAAAAAAGAAGAAATATAA

Upstream 100 bases:

>100_bases
TTCTCATATGGTAGATATTTAGAAAACCAATTAAGAGAAAGTTTTGATTTTGATGGAACTGGTATAGAAATAGAATATAG
AGCTAGAAAGGAGTAATTTT

Downstream 100 bases:

>100_bases
AATTTGATTTAAAAGAGATAGAAAATTTTCTATCTCTTTTTATTTTAATTAAAAGTGGGCCGTGTTAAAAAATATTTTTT
ATGTAGTTATAAATTTATGC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSKVAFLGAGSFGTSLGILLGNKGVTVSLWDRDENVINDINVNRKNDKYIKDLTIPTNVTAYKDLDEALNGAEYVVLAVP
SHVIRTACKNLKGKINDDVIIINIAKGIEEGTNLRLSQVINQELPNNKVVVLSGPSHAEEVSKGIPTTLVASSECMECAE
KVQDLFMDKNFRIYTNDDIIGVEIGGAVKNIIALAAGVCDGIGYGDNSKAALMTRGMAEIARIGIKMGGKAETFFGLTGM
GDLIVTCTSMHSRNRRAGILIGQGKTAEEAIEEVGMVVEGIKACKAFYELKEKEGVTMPITDIAYKVLFEGAKAENAVSL
LMERDKKKEEI

Sequences:

>Translated_331_residues
MSKVAFLGAGSFGTSLGILLGNKGVTVSLWDRDENVINDINVNRKNDKYIKDLTIPTNVTAYKDLDEALNGAEYVVLAVP
SHVIRTACKNLKGKINDDVIIINIAKGIEEGTNLRLSQVINQELPNNKVVVLSGPSHAEEVSKGIPTTLVASSECMECAE
KVQDLFMDKNFRIYTNDDIIGVEIGGAVKNIIALAAGVCDGIGYGDNSKAALMTRGMAEIARIGIKMGGKAETFFGLTGM
GDLIVTCTSMHSRNRRAGILIGQGKTAEEAIEEVGMVVEGIKACKAFYELKEKEGVTMPITDIAYKVLFEGAKAENAVSL
LMERDKKKEEI
>Mature_330_residues
SKVAFLGAGSFGTSLGILLGNKGVTVSLWDRDENVINDINVNRKNDKYIKDLTIPTNVTAYKDLDEALNGAEYVVLAVPS
HVIRTACKNLKGKINDDVIIINIAKGIEEGTNLRLSQVINQELPNNKVVVLSGPSHAEEVSKGIPTTLVASSECMECAEK
VQDLFMDKNFRIYTNDDIIGVEIGGAVKNIIALAAGVCDGIGYGDNSKAALMTRGMAEIARIGIKMGGKAETFFGLTGMG
DLIVTCTSMHSRNRRAGILIGQGKTAEEAIEEVGMVVEGIKACKAFYELKEKEGVTMPITDIAYKVLFEGAKAENAVSLL
MERDKKKEEI

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI24307999, Length=340, Percent_Identity=32.3529411764706, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI33695088, Length=333, Percent_Identity=30.9309309309309, Blast_Score=139, Evalue=4e-33,
Organism=Escherichia coli, GI1790037, Length=331, Percent_Identity=39.2749244712991, Blast_Score=255, Evalue=4e-69,
Organism=Caenorhabditis elegans, GI32564399, Length=330, Percent_Identity=31.5151515151515, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI193210136, Length=339, Percent_Identity=30.9734513274336, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI32564403, Length=339, Percent_Identity=30.9734513274336, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17507425, Length=343, Percent_Identity=28.8629737609329, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI193210134, Length=237, Percent_Identity=31.6455696202532, Blast_Score=85, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6324513, Length=355, Percent_Identity=29.0140845070423, Blast_Score=131, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320181, Length=355, Percent_Identity=29.0140845070423, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI17136204, Length=291, Percent_Identity=34.020618556701, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17136200, Length=291, Percent_Identity=34.020618556701, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17136202, Length=291, Percent_Identity=34.020618556701, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI22026922, Length=306, Percent_Identity=26.1437908496732, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI281362270, Length=295, Percent_Identity=24.406779661017, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI45551945, Length=295, Percent_Identity=24.406779661017, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24648969, Length=255, Percent_Identity=25.4901960784314, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_CLOP1 (Q0TPK0)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696440.1
- ProteinModelPortal:   Q0TPK0
- SMR:   Q0TPK0
- STRING:   Q0TPK0
- GeneID:   4202431
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_2007
- TIGR:   CPF_2007
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   SQTLRGN
- ProtClustDB:   PRK00094
- BioCyc:   CPER195103:CPF_2007-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 35650; Mature: 35518

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 189-189 BINDING 106-106 BINDING 106-106 BINDING 138-138 BINDING 253-253 BINDING 279-279

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVAFLGAGSFGTSLGILLGNKGVTVSLWDRDENVINDINVNRKNDKYIKDLTIPTNVT
CCCEEEEECCCCCCEEEEEECCCCCEEEEECCCCCHHHCCCCCCCCCCEEEEEECCCCCH
AYKDLDEALNGAEYVVLAVPSHVIRTACKNLKGKINDDVIIINIAKGIEEGTNLRLSQVI
HHHHHHHHCCCCCEEEEECCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHH
NQELPNNKVVVLSGPSHAEEVSKGIPTTLVASSECMECAEKVQDLFMDKNFRIYTNDDII
HHHCCCCCEEEEECCCHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCEE
GVEIGGAVKNIIALAAGVCDGIGYGDNSKAALMTRGMAEIARIGIKMGGKAETFFGLTGM
EEEECHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
GDLIVTCTSMHSRNRRAGILIGQGKTAEEAIEEVGMVVEGIKACKAFYELKEKEGVTMPI
CHHEEEEHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TDIAYKVLFEGAKAENAVSLLMERDKKKEEI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKVAFLGAGSFGTSLGILLGNKGVTVSLWDRDENVINDINVNRKNDKYIKDLTIPTNVT
CCEEEEECCCCCCEEEEEECCCCCEEEEECCCCCHHHCCCCCCCCCCEEEEEECCCCCH
AYKDLDEALNGAEYVVLAVPSHVIRTACKNLKGKINDDVIIINIAKGIEEGTNLRLSQVI
HHHHHHHHCCCCCEEEEECCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHH
NQELPNNKVVVLSGPSHAEEVSKGIPTTLVASSECMECAEKVQDLFMDKNFRIYTNDDII
HHHCCCCCEEEEECCCHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCEE
GVEIGGAVKNIIALAAGVCDGIGYGDNSKAALMTRGMAEIARIGIKMGGKAETFFGLTGM
EEEECHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
GDLIVTCTSMHSRNRRAGILIGQGKTAEEAIEEVGMVVEGIKACKAFYELKEKEGVTMPI
CHHEEEEHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TDIAYKVLFEGAKAENAVSLLMERDKKKEEI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA