Click here to switch to the map view.

The map label for this gene is recG [H]

Identifier: 18310713

GI number: 18310713

Start: 2007021

End: 2009093

Strand: Reverse

Name: recG [H]

Synonym: CPE1731

Alternate gene names: 18310713

Gene position: 2009093-2007021 (Counterclockwise)

Preceding gene: 18310714

Following gene: 18310712

Centisome position: 66.28

GC content: 28.32

Gene sequence:

>2073_bases
ATGATTAAATTAGCTTTATTATTTAAGGAGGGGATTAGGATTAACATATACGATGATATAGGATTAGTAAAAGGTGTTGG
GCCTAAGCTTAAAGAGAGACTTAATAAAGTTGGTATATTTACTGTTTTAGATTTACTTTTATATTTTCCAAGGGACTATG
AATTTTTAAATGATGATATAAGTTTAAATGGAGATATAAGTGATGAAAAAGCTATTTTAAAATGTAAAGTTCAAAGTTAT
GGAAGTTCAATAAGAACTAGAAATGGAAAAACTTTAACCACAATTAACTTTACATATAATAACTTAAAGGTTATAGGGAA
ATGGTTTAATCAGCCTTATATAAAAAGGAATTTCATTTTAGGTAATGAATATAATCTTATGGGGAAATTTAAAAAGGTTA
ATAATACTCTAGAGGTTATTAATCCATTAATACCTTGTAAAGAAGCTAATAAAAGTGAGATTTTACCTATATATACTTTG
AAAAATGGATTAACAAACAAAATTTTAGTTAAGCTTATAAATGAAATACTTAAGAATATGATTATAAAAGAAAATTTACC
AGAGGAAATAGTAAAAAAGTATAAACTTATATCCCTAGATAAAGCTATAAGAAGCATACATTTTCCAGAGGGTAGAGGAG
AATTACAAAGTGCAATAAATAGACTTAAGTTTCAAGAGTTATTTACATATTCTCTAAAAATAATAATGATGAAGGCTCAT
ATAAAAAAAGAAAATAGCGGAATAAGCTTTAAAATGAGTCCTCTTCTTAAGGATTTAAAAGAGTCACTTCCATATACTTT
AACTAATGCACAATCAAGAACCCTTAGAGAAATACTTCTAGATCAAAAGAGAAATATTGCAATGAATAGATTAGTTCAAG
GAGATGTTGGATCAGGAAAAACTTTAGTAGCATTAATATCTATGTTTAACGTGTACATGAATGGATATCAAACTGTTCTT
ATGGCACCTACAGAAATATTAGCTAATCAACATTATGCTGAAGCCAAAAAATATTTAGAGCAATTTGGAGTTGATATAGA
GCTTTTAACTGGAAGTACTAAGGAAAAAGAGAAGAAGAGAATAAAAGAGAAGATAGCCTCAGGAAAAGGAATAATGTTAA
TAGGAACTCATGCCTTAATACAGGATGATGTTGAATTAAACAATTTAGGTCTTGTGGTAACAGATGAGCAACATAGATTT
GGAGTAGAACAGAGAAGTAGACTTATAAATAAAAATAAGAGAGCGGATGTTTTAGTAATGACTGCTACCCCTATTCCAAG
AACTCTTTCCTTATATTTATATAGTGACTTGGATATTTCTATAATAGATGAATTACCTCCAGGAAGAAAGCCAATAGATA
CTATGCTAGTAGATATGAATCAAAGAATGAAGGCTTATAACTTTGCTTTAAAGGAAGTAGAGAAAGGAAGACAATTCTAT
ATAGTATCACCTTTAATAGAGGAAAATGAAAAGTTAAATCTAAACTCTGTTGAAAAAATTTATGAAGAACTTAAAAATGG
AATCTTTAAGGATATAAGAATTGAAATTTTACACGGTAAGATGGCTGGAAAAGATAAGGATAAAATTATAAATACCTTTA
AAAATGGGGAAATAAAAGGTATAATATCTACAACGGTTATAGAAGTAGGTGTTAATGTACCAAACTCTACAATGATGATT
ATAGAAAATGCAGAGAGGTTTGGTTTAGCACAACTTCATCAACTTAGAGGAAGAGTTGGAAGAGGAGAACATAAGTCTTA
TTGTATTCTTATAGCTAATACTAAAAATGATATTACTAGAAGAAGGATGGAAATAATGACAGAGAGTTCAGATGGTTTTT
ATATTGCAGAAGAGGATTTAAAACTAAGAGGTGCTGGGGAAGTCTTTGGAATGAGACAGCATGGAGATGAAGGATTTATT
CTAGCTAATGTAGTTGATGATATAAATATATTAAAATGTGCTAATCATGAAGCTAAATTAATAGTAAATAATATAAATGA
AGATAATAAAAAGCTTTGTACAGAAATAATGAGGGGAATTGAAAGAAATAGTAGGTATATTTGTTTCAATTAG

Upstream 100 bases:

>100_bases
TAGAAATTTTATTATAGGGTTATAGCTATAAGTTTTATGGTTATAATCCTTTAATTTTGCAATTTTAAGAATGTAATTAA
AGTATATTATTTTTTTATAG

Downstream 100 bases:

>100_bases
TAAATTGTTCAAAAACTAGTAATATGATAAAATAATTAAGGAAAATCAAAGGAGGACATTATAAATGAGAATAATAGCAG
GAAAAGCAAGAGGAAGAAAA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 690; Mature: 690

Protein sequence:

>690_residues
MIKLALLFKEGIRINIYDDIGLVKGVGPKLKERLNKVGIFTVLDLLLYFPRDYEFLNDDISLNGDISDEKAILKCKVQSY
GSSIRTRNGKTLTTINFTYNNLKVIGKWFNQPYIKRNFILGNEYNLMGKFKKVNNTLEVINPLIPCKEANKSEILPIYTL
KNGLTNKILVKLINEILKNMIIKENLPEEIVKKYKLISLDKAIRSIHFPEGRGELQSAINRLKFQELFTYSLKIIMMKAH
IKKENSGISFKMSPLLKDLKESLPYTLTNAQSRTLREILLDQKRNIAMNRLVQGDVGSGKTLVALISMFNVYMNGYQTVL
MAPTEILANQHYAEAKKYLEQFGVDIELLTGSTKEKEKKRIKEKIASGKGIMLIGTHALIQDDVELNNLGLVVTDEQHRF
GVEQRSRLINKNKRADVLVMTATPIPRTLSLYLYSDLDISIIDELPPGRKPIDTMLVDMNQRMKAYNFALKEVEKGRQFY
IVSPLIEENEKLNLNSVEKIYEELKNGIFKDIRIEILHGKMAGKDKDKIINTFKNGEIKGIISTTVIEVGVNVPNSTMMI
IENAERFGLAQLHQLRGRVGRGEHKSYCILIANTKNDITRRRMEIMTESSDGFYIAEEDLKLRGAGEVFGMRQHGDEGFI
LANVVDDINILKCANHEAKLIVNNINEDNKKLCTEIMRGIERNSRYICFN

Sequences:

>Translated_690_residues
MIKLALLFKEGIRINIYDDIGLVKGVGPKLKERLNKVGIFTVLDLLLYFPRDYEFLNDDISLNGDISDEKAILKCKVQSY
GSSIRTRNGKTLTTINFTYNNLKVIGKWFNQPYIKRNFILGNEYNLMGKFKKVNNTLEVINPLIPCKEANKSEILPIYTL
KNGLTNKILVKLINEILKNMIIKENLPEEIVKKYKLISLDKAIRSIHFPEGRGELQSAINRLKFQELFTYSLKIIMMKAH
IKKENSGISFKMSPLLKDLKESLPYTLTNAQSRTLREILLDQKRNIAMNRLVQGDVGSGKTLVALISMFNVYMNGYQTVL
MAPTEILANQHYAEAKKYLEQFGVDIELLTGSTKEKEKKRIKEKIASGKGIMLIGTHALIQDDVELNNLGLVVTDEQHRF
GVEQRSRLINKNKRADVLVMTATPIPRTLSLYLYSDLDISIIDELPPGRKPIDTMLVDMNQRMKAYNFALKEVEKGRQFY
IVSPLIEENEKLNLNSVEKIYEELKNGIFKDIRIEILHGKMAGKDKDKIINTFKNGEIKGIISTTVIEVGVNVPNSTMMI
IENAERFGLAQLHQLRGRVGRGEHKSYCILIANTKNDITRRRMEIMTESSDGFYIAEEDLKLRGAGEVFGMRQHGDEGFI
LANVVDDINILKCANHEAKLIVNNINEDNKKLCTEIMRGIERNSRYICFN
>Mature_690_residues
MIKLALLFKEGIRINIYDDIGLVKGVGPKLKERLNKVGIFTVLDLLLYFPRDYEFLNDDISLNGDISDEKAILKCKVQSY
GSSIRTRNGKTLTTINFTYNNLKVIGKWFNQPYIKRNFILGNEYNLMGKFKKVNNTLEVINPLIPCKEANKSEILPIYTL
KNGLTNKILVKLINEILKNMIIKENLPEEIVKKYKLISLDKAIRSIHFPEGRGELQSAINRLKFQELFTYSLKIIMMKAH
IKKENSGISFKMSPLLKDLKESLPYTLTNAQSRTLREILLDQKRNIAMNRLVQGDVGSGKTLVALISMFNVYMNGYQTVL
MAPTEILANQHYAEAKKYLEQFGVDIELLTGSTKEKEKKRIKEKIASGKGIMLIGTHALIQDDVELNNLGLVVTDEQHRF
GVEQRSRLINKNKRADVLVMTATPIPRTLSLYLYSDLDISIIDELPPGRKPIDTMLVDMNQRMKAYNFALKEVEKGRQFY
IVSPLIEENEKLNLNSVEKIYEELKNGIFKDIRIEILHGKMAGKDKDKIINTFKNGEIKGIISTTVIEVGVNVPNSTMMI
IENAERFGLAQLHQLRGRVGRGEHKSYCILIANTKNDITRRRMEIMTESSDGFYIAEEDLKLRGAGEVFGMRQHGDEGFI
LANVVDDINILKCANHEAKLIVNNINEDNKKLCTEIMRGIERNSRYICFN

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=702, Percent_Identity=36.1823361823362, Blast_Score=404, Evalue=1e-113,
Organism=Escherichia coli, GI1787357, Length=400, Percent_Identity=36.75, Blast_Score=256, Evalue=5e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 78809; Mature: 78809

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLALLFKEGIRINIYDDIGLVKGVGPKLKERLNKVGIFTVLDLLLYFPRDYEFLNDDI
CEEEEEEECCCCEEEEEECCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCE
SLNGDISDEKAILKCKVQSYGSSIRTRNGKTLTTINFTYNNLKVIGKWFNQPYIKRNFIL
EECCCCCCCCEEEEEEHHHHCCHHCCCCCCEEEEEEEEECCHHHHHHHHCCCCEEEEEEE
GNEYNLMGKFKKVNNTLEVINPLIPCKEANKSEILPIYTLKNGLTNKILVKLINEILKNM
CCCCCHHHHHHHHCCHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
IIKENLPEEIVKKYKLISLDKAIRSIHFPEGRGELQSAINRLKFQELFTYSLKIIMMKAH
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEHH
IKKENSGISFKMSPLLKDLKESLPYTLTNAQSRTLREILLDQKRNIAMNRLVQGDVGSGK
HCCCCCCCEEEHHHHHHHHHHHCCEEEECCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCH
TLVALISMFNVYMNGYQTVLMAPTEILANQHYAEAKKYLEQFGVDIELLTGSTKEKEKKR
HHHHHHHHHHHHHCCCEEEEECCHHHHHCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHH
IKEKIASGKGIMLIGTHALIQDDVELNNLGLVVTDEQHRFGVEQRSRLINKNKRADVLVM
HHHHHHCCCCEEEEECHHHHCCCCEECCEEEEEECCHHHCCHHHHHHHHCCCCCCCEEEE
TATPIPRTLSLYLYSDLDISIIDELPPGRKPIDTMLVDMNQRMKAYNFALKEVEKGRQFY
ECCCCCCEEEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IVSPLIEENEKLNLNSVEKIYEELKNGIFKDIRIEILHGKMAGKDKDKIINTFKNGEIKG
EECCHHCCCCCCCCHHHHHHHHHHHCCCHHEEEEEEEECCCCCCCHHHHHHHHCCCCEEE
IISTTVIEVGVNVPNSTMMIIENAERFGLAQLHQLRGRVGRGEHKSYCILIANTKNDITR
EEEEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHH
RRMEIMTESSDGFYIAEEDLKLRGAGEVFGMRQHGDEGFILANVVDDINILKCANHEAKL
HHHHHHCCCCCCEEEEECCCEEECCCCEEEEHCCCCCCEEEEEECCCCCEEEECCCCCEE
IVNNINEDNKKLCTEIMRGIERNSRYICFN
EEECCCCCHHHHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure
MIKLALLFKEGIRINIYDDIGLVKGVGPKLKERLNKVGIFTVLDLLLYFPRDYEFLNDDI
CEEEEEEECCCCEEEEEECCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCE
SLNGDISDEKAILKCKVQSYGSSIRTRNGKTLTTINFTYNNLKVIGKWFNQPYIKRNFIL
EECCCCCCCCEEEEEEHHHHCCHHCCCCCCEEEEEEEEECCHHHHHHHHCCCCEEEEEEE
GNEYNLMGKFKKVNNTLEVINPLIPCKEANKSEILPIYTLKNGLTNKILVKLINEILKNM
CCCCCHHHHHHHHCCHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
IIKENLPEEIVKKYKLISLDKAIRSIHFPEGRGELQSAINRLKFQELFTYSLKIIMMKAH
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEHH
IKKENSGISFKMSPLLKDLKESLPYTLTNAQSRTLREILLDQKRNIAMNRLVQGDVGSGK
HCCCCCCCEEEHHHHHHHHHHHCCEEEECCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCH
TLVALISMFNVYMNGYQTVLMAPTEILANQHYAEAKKYLEQFGVDIELLTGSTKEKEKKR
HHHHHHHHHHHHHCCCEEEEECCHHHHHCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHH
IKEKIASGKGIMLIGTHALIQDDVELNNLGLVVTDEQHRFGVEQRSRLINKNKRADVLVM
HHHHHHCCCCEEEEECHHHHCCCCEECCEEEEEECCHHHCCHHHHHHHHCCCCCCCEEEE
TATPIPRTLSLYLYSDLDISIIDELPPGRKPIDTMLVDMNQRMKAYNFALKEVEKGRQFY
ECCCCCCEEEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IVSPLIEENEKLNLNSVEKIYEELKNGIFKDIRIEILHGKMAGKDKDKIINTFKNGEIKG
EECCHHCCCCCCCCHHHHHHHHHHHCCCHHEEEEEEEECCCCCCCHHHHHHHHCCCCEEE
IISTTVIEVGVNVPNSTMMIIENAERFGLAQLHQLRGRVGRGEHKSYCILIANTKNDITR
EEEEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHH
RRMEIMTESSDGFYIAEEDLKLRGAGEVFGMRQHGDEGFILANVVDDINILKCANHEAKL
HHHHHHCCCCCCEEEEECCCEEECCCCEEEEHCCCCCCEEEEEECCCCCEEEECCCCCEE
IVNNINEDNKKLCTEIMRGIERNSRYICFN
EEECCCCCHHHHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8830261; 11463916 [H]