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The map label for this gene is aspC [C]

Identifier: 18310652

GI number: 18310652

Start: 1944433

End: 1945626

Strand: Reverse

Name: aspC [C]

Synonym: CPE1670

Alternate gene names: 18310652

Gene position: 1945626-1944433 (Counterclockwise)

Preceding gene: 18310653

Following gene: 18310651

Centisome position: 64.18

GC content: 30.07

Gene sequence:

>1194_bases
ATGATATTATCTAGAAAAGCACAAAATATAGGGGCATCACTAACTTTAGCCTTAACAGCTAAAGCAGGTGAATTAAAAAA
AGAAGGAATAGATGTAGTAAGCTTTGGAGTAGGTGAGCCGGATTTTAATACACCTAAGAATATAATAGAAGCTGCCACTA
GAGCTATGGAAGAAGGAAAGACAAAATACACAGCCACATCTGGAATAGTAGAGTTAAAAGAGGCCATAGCAAGGAAATTA
CATGATGATAATGGACTTAACTATGGAACTAAAAATATAATTATTTCAACAGGAGCTAAACAATCTTTAGCCAATGTATT
TATGGCGATTTTAAATCCAGGAGATGAGGTTATAATACCAGTACCATATTGGGTAAGTTATCCTGAGTTAGTTAAATTAA
GTGATGGAGTTCCTGTTTTTATAGAAACAAAAAAAGAAAATGATTTTAAGGTTACTTATGACGAATTAAAATCAGTTTTA
AGTGAAAATACAAAGGCAATAGTAATAAATTCACCAAATAATCCAACAGGAACAGTATATTCAAAAAAAGATTTAGAAGT
TATTGCTAAATTTGCTGAAGAAAATGATCTTATAATAATTTCTGATGAAATATATGAAAAACTTATATATGGAAAAGAAG
AGCATATAAGTATTGCTTCCTTAAGTGAAGATGCCTTCAAGAGAACAGTAGTTATAAATGGATTTTCTAAGGCTTATGCA
ATGACTGGATGGAGAATTGGATATGCAGCTTGTTATAATGAAGAGCTAATTAAGGTAATGAACAATGTTCAGAGTCATAT
GACATCAAATACAAATAGTATAGCTCAATTTGCTGCATTAGAAGCCTTAAATGGAGATCAAGAAACTATAAAGAATATGG
TTAAGGAATTTAGTTTAAGAAGAGAGCTTATGATAGAACTTATAAGTGAAATTGAGGATCTTACTTTTATAGAGCCAAAG
GGTGCCTTTTATGTAATGATTGATGTGTCTAAGGTTCTAAAAAAAGCTAATATAAAGGGTTCAATGGAATTTGCAAATCT
ATTACTAAAAGAGGAAAATGTTGTTGTAATACCTGGAATAGCTTTTGGGGAAGATAATTTTATAAGACTATCTTATGCTA
CATCTAAAGAGGAAATAATTAAGGGCTTAAAAAGAATAAAAGAATTTGTTAATAAACTTATGAATAGGGATTAA

Upstream 100 bases:

>100_bases
TTAACTTATAGCAGTATTTTTTATTGGTTTACTTTAAATAATAAAAATGATATATTGGAAGCGTAATAAAATAAATTTAA
AGCAGTAAAGAGGGGATTAG

Downstream 100 bases:

>100_bases
TCTTTTCTTAAGTTGTTGAAATTTTCTAAAAAAATGAGTATAATTAAGAAGTTAGTATTATTAAATAACAAATAAAAGTA
AAGAGGTGTTTATAATGGTA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MILSRKAQNIGASLTLALTAKAGELKKEGIDVVSFGVGEPDFNTPKNIIEAATRAMEEGKTKYTATSGIVELKEAIARKL
HDDNGLNYGTKNIIISTGAKQSLANVFMAILNPGDEVIIPVPYWVSYPELVKLSDGVPVFIETKKENDFKVTYDELKSVL
SENTKAIVINSPNNPTGTVYSKKDLEVIAKFAEENDLIIISDEIYEKLIYGKEEHISIASLSEDAFKRTVVINGFSKAYA
MTGWRIGYAACYNEELIKVMNNVQSHMTSNTNSIAQFAALEALNGDQETIKNMVKEFSLRRELMIELISEIEDLTFIEPK
GAFYVMIDVSKVLKKANIKGSMEFANLLLKEENVVVIPGIAFGEDNFIRLSYATSKEEIIKGLKRIKEFVNKLMNRD

Sequences:

>Translated_397_residues
MILSRKAQNIGASLTLALTAKAGELKKEGIDVVSFGVGEPDFNTPKNIIEAATRAMEEGKTKYTATSGIVELKEAIARKL
HDDNGLNYGTKNIIISTGAKQSLANVFMAILNPGDEVIIPVPYWVSYPELVKLSDGVPVFIETKKENDFKVTYDELKSVL
SENTKAIVINSPNNPTGTVYSKKDLEVIAKFAEENDLIIISDEIYEKLIYGKEEHISIASLSEDAFKRTVVINGFSKAYA
MTGWRIGYAACYNEELIKVMNNVQSHMTSNTNSIAQFAALEALNGDQETIKNMVKEFSLRRELMIELISEIEDLTFIEPK
GAFYVMIDVSKVLKKANIKGSMEFANLLLKEENVVVIPGIAFGEDNFIRLSYATSKEEIIKGLKRIKEFVNKLMNRD
>Mature_397_residues
MILSRKAQNIGASLTLALTAKAGELKKEGIDVVSFGVGEPDFNTPKNIIEAATRAMEEGKTKYTATSGIVELKEAIARKL
HDDNGLNYGTKNIIISTGAKQSLANVFMAILNPGDEVIIPVPYWVSYPELVKLSDGVPVFIETKKENDFKVTYDELKSVL
SENTKAIVINSPNNPTGTVYSKKDLEVIAKFAEENDLIIISDEIYEKLIYGKEEHISIASLSEDAFKRTVVINGFSKAYA
MTGWRIGYAACYNEELIKVMNNVQSHMTSNTNSIAQFAALEALNGDQETIKNMVKEFSLRRELMIELISEIEDLTFIEPK
GAFYVMIDVSKVLKKANIKGSMEFANLLLKEENVVVIPGIAFGEDNFIRLSYATSKEEIIKGLKRIKEFVNKLMNRD

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=376, Percent_Identity=27.1276595744681, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI169881279, Length=376, Percent_Identity=27.1276595744681, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI56713254, Length=393, Percent_Identity=28.7531806615776, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI56713256, Length=393, Percent_Identity=28.7531806615776, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI4507369, Length=379, Percent_Identity=23.7467018469657, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI169881281, Length=373, Percent_Identity=25.201072386059, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI215599424, Length=369, Percent_Identity=23.8482384823848, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI19263340, Length=369, Percent_Identity=23.8482384823848, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4885351, Length=347, Percent_Identity=24.207492795389, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI187936925, Length=352, Percent_Identity=21.3068181818182, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI14211921, Length=352, Percent_Identity=21.3068181818182, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI149944424, Length=226, Percent_Identity=25.2212389380531, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1786816, Length=396, Percent_Identity=26.2626262626263, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1788722, Length=401, Percent_Identity=28.428927680798, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1788627, Length=377, Percent_Identity=28.9124668435013, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1787909, Length=374, Percent_Identity=21.3903743315508, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790797, Length=379, Percent_Identity=24.5382585751979, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17567663, Length=380, Percent_Identity=25, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71994476, Length=421, Percent_Identity=26.603325415677, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71994472, Length=421, Percent_Identity=26.603325415677, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17567369, Length=403, Percent_Identity=26.302729528536, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI71981209, Length=405, Percent_Identity=21.7283950617284, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71981215, Length=186, Percent_Identity=23.6559139784946, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=24.6786632390745, Blast_Score=138, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6320317, Length=386, Percent_Identity=22.5388601036269, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6323118, Length=384, Percent_Identity=21.09375, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI28573069, Length=392, Percent_Identity=27.0408163265306, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24646114, Length=392, Percent_Identity=27.0408163265306, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28573067, Length=392, Percent_Identity=27.0408163265306, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28573065, Length=392, Percent_Identity=27.0408163265306, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI18859735, Length=374, Percent_Identity=23.2620320855615, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24641770, Length=370, Percent_Identity=23.5135135135135, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24641760, Length=370, Percent_Identity=23.5135135135135, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24641768, Length=370, Percent_Identity=23.5135135135135, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24641766, Length=370, Percent_Identity=23.5135135135135, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24641764, Length=370, Percent_Identity=23.5135135135135, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45551451, Length=370, Percent_Identity=23.5135135135135, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44163; Mature: 44163

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILSRKAQNIGASLTLALTAKAGELKKEGIDVVSFGVGEPDFNTPKNIIEAATRAMEEGK
CCCCCCCCCCCCEEEEEEEECCCHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCC
TKYTATSGIVELKEAIARKLHDDNGLNYGTKNIIISTGAKQSLANVFMAILNPGDEVIIP
CEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCEEEE
VPYWVSYPELVKLSDGVPVFIETKKENDFKVTYDELKSVLSENTKAIVINSPNNPTGTVY
CCCCCCCHHHEEECCCCEEEEEECCCCCCEEEHHHHHHHHCCCCCEEEEECCCCCCCCEE
SKKDLEVIAKFAEENDLIIISDEIYEKLIYGKEEHISIASLSEDAFKRTVVINGFSKAYA
CHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCHHCEEEEECCHHHHHEEEEEECCHHHHH
MTGWRIGYAACYNEELIKVMNNVQSHMTSNTNSIAQFAALEALNGDQETIKNMVKEFSLR
HCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RELMIELISEIEDLTFIEPKGAFYVMIDVSKVLKKANIKGSMEFANLLLKEENVVVIPGI
HHHHHHHHHHHHHCEEECCCCCEEEEEEHHHHHHHHCCCCCHHHHHHHCCCCCEEEECCE
AFGEDNFIRLSYATSKEEIIKGLKRIKEFVNKLMNRD
EECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MILSRKAQNIGASLTLALTAKAGELKKEGIDVVSFGVGEPDFNTPKNIIEAATRAMEEGK
CCCCCCCCCCCCEEEEEEEECCCHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCC
TKYTATSGIVELKEAIARKLHDDNGLNYGTKNIIISTGAKQSLANVFMAILNPGDEVIIP
CEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCEEEE
VPYWVSYPELVKLSDGVPVFIETKKENDFKVTYDELKSVLSENTKAIVINSPNNPTGTVY
CCCCCCCHHHEEECCCCEEEEEECCCCCCEEEHHHHHHHHCCCCCEEEEECCCCCCCCEE
SKKDLEVIAKFAEENDLIIISDEIYEKLIYGKEEHISIASLSEDAFKRTVVINGFSKAYA
CHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCHHCEEEEECCHHHHHEEEEEECCHHHHH
MTGWRIGYAACYNEELIKVMNNVQSHMTSNTNSIAQFAALEALNGDQETIKNMVKEFSLR
HCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RELMIELISEIEDLTFIEPKGAFYVMIDVSKVLKKANIKGSMEFANLLLKEENVVVIPGI
HHHHHHHHHHHHHCEEECCCCCEEEEEEHHHHHHHHCCCCCHHHHHHHCCCCCEEEECCE
AFGEDNFIRLSYATSKEEIIKGLKRIKEFVNKLMNRD
EECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1990006; 2155199 [H]