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The map label for this gene is argS

Identifier: 18310643

GI number: 18310643

Start: 1933553

End: 1935250

Strand: Reverse

Name: argS

Synonym: CPE1661

Alternate gene names: 18310643

Gene position: 1935250-1933553 (Counterclockwise)

Preceding gene: 18310645

Following gene: 18310640

Centisome position: 63.84

GC content: 30.8

Gene sequence:

>1698_bases
ATGGATTACAAAAAGTTAGTTGCAGAAAGAATTAAAGAACATGTTGATCTAGAATTAGAAAACATAGAAAAACTTATAGA
AATACCACCTAAGCCAGAAATGGGAGATTTTGCATTCCCTTGCTTCCAATTAGCAAAGGTTATGAGAAAAGCTCCTAATA
TGATAGCTGCTGAATTAGCTGAAAAGATAAATAAAGAGGGATTTGAAAGAGTAGAGTGTTTAGGACCTTACTTAAACTTC
TTTGTTGATAAAGTAGCTTTCTCAAAAAATATAATAAGCAAAGTTTTAGAAGAAGGAGATAAATATGGTTCTTCTAAAAT
AGGAGAGGGTAAAAATGTTGTAGTTGAATATTCATCACCTAACATAGCTAAGCCTTTCCACGTTGGACATTTATTCACAA
CAGCTATAGGACATTCATTATATAGAATGTTAAACTTTGAAGGATATAATCCAATAAGAATAAATCACTTAGGAGACTGG
GGAACTCAGTTTGGTAAGTTAATCTCAGCTTATAAAAGATGGGGAAATGAAGAAGCTTTAGAAGAGGCTCCAATAAATGA
GCTTTTAAGAATATATGTTAAATTCCATGATGAAGCTGAAAATAATCCAGAACTTGAAGATGAAGGAAGAATGTACTTTA
AGAAGCTTGAAGATGGAGATCAAGAAGCTGTAGCTCTATGGGAAAGATTTAAAGACTTATCTTTAAAAGAATTTAATAAG
ATATATGATATGTTAGGCGTAGATTTCGATTCTTGGGCTGGAGAAAGCTTTTACAATGATAAGATGGATAAAGTAGTAGA
AGAATTAGAAAAGGCTAATATATTAACTGAGAGTAATGGTGCTAAGGTTGTAATGTTAGATGAATACAATATGCCACCTT
GTATAGTTGTTAAATCAGATGGAGCATCAATATATGCTACAAGAGACTTAGCAGCAGCTAGTTATAGACATAAAACATAT
AACTTTGATAAATGTATATATGTAGTTGGTAAAGACCAAATATTACACTTTAACCAAGTATTCAAAACATTAGAATTAGC
AGGTAATGAATGGGCTAAAAATTGCGTACACATTCCATTTGGATTAGTTAAGTTCGCAGATAGAAAGCTTTCAACAAGAA
AAGGTAATGTAGTTTTACTTGAAGATTTATTAAACGAAGCTATAGATAAAACAAGAGAAACTATAGAAGAAAAGAACCCA
CAATTAGAAAATAAAGAGGAAGTAGCTAAGAAAATAGGTATAGGAGCTATATTATTTACTTACTTAAAGAACTCAAGAGA
AAGAGATATAGTTTTTGATTGGAAAGAGATGTTAAGCTTTGATGGAGAAACTGGTCCATATGTTCAATACTCATATGCAA
GAGCTAAGAGTATATTAAGAAAAGCTGAGGAACAAAAAATAACAGCTGAGCCAGATTTCACAAAGTTAACTTCAAAAGAA
GAGTTTGAATTAGCTAAAACTCTAGAAGGATTACAAAAGGCTGTAATTTTAGGAATAGATAAGTTAGAACCTTCAGTTGT
AACTAGATATTCAATAGAAGTAGCTAAGGCTTTCAATAAATTCTACAATAATCATACAGTTTTAAATGTAGAAGATGAAG
GATTAAAGGCTGCAAGACTTGAGCTTATAAAAGCTACTGCTCAAGTTATTAAAAATGCTTTATTCTTAATAGGAATAGAT
GTAGTTGAAAAAATGTAA

Upstream 100 bases:

>100_bases
TACAAAGAGGCGGTTTTTTATATTGTAAATAAATTTATATTTTGGCAATAATGTCATTATAAGATATGTTTTAAAAAGAT
ATAAAATAAGGAGGACAATT

Downstream 100 bases:

>100_bases
TTTATAATAAAAAATAACCAATTCCATTTGGAATTGGTTATTTTTTTACTTCTTATTATCTTTTCTACTAGGACAACTTC
CTTTTGAAGCACATCCACTG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MDYKKLVAERIKEHVDLELENIEKLIEIPPKPEMGDFAFPCFQLAKVMRKAPNMIAAELAEKINKEGFERVECLGPYLNF
FVDKVAFSKNIISKVLEEGDKYGSSKIGEGKNVVVEYSSPNIAKPFHVGHLFTTAIGHSLYRMLNFEGYNPIRINHLGDW
GTQFGKLISAYKRWGNEEALEEAPINELLRIYVKFHDEAENNPELEDEGRMYFKKLEDGDQEAVALWERFKDLSLKEFNK
IYDMLGVDFDSWAGESFYNDKMDKVVEELEKANILTESNGAKVVMLDEYNMPPCIVVKSDGASIYATRDLAAASYRHKTY
NFDKCIYVVGKDQILHFNQVFKTLELAGNEWAKNCVHIPFGLVKFADRKLSTRKGNVVLLEDLLNEAIDKTRETIEEKNP
QLENKEEVAKKIGIGAILFTYLKNSRERDIVFDWKEMLSFDGETGPYVQYSYARAKSILRKAEEQKITAEPDFTKLTSKE
EFELAKTLEGLQKAVILGIDKLEPSVVTRYSIEVAKAFNKFYNNHTVLNVEDEGLKAARLELIKATAQVIKNALFLIGID
VVEKM

Sequences:

>Translated_565_residues
MDYKKLVAERIKEHVDLELENIEKLIEIPPKPEMGDFAFPCFQLAKVMRKAPNMIAAELAEKINKEGFERVECLGPYLNF
FVDKVAFSKNIISKVLEEGDKYGSSKIGEGKNVVVEYSSPNIAKPFHVGHLFTTAIGHSLYRMLNFEGYNPIRINHLGDW
GTQFGKLISAYKRWGNEEALEEAPINELLRIYVKFHDEAENNPELEDEGRMYFKKLEDGDQEAVALWERFKDLSLKEFNK
IYDMLGVDFDSWAGESFYNDKMDKVVEELEKANILTESNGAKVVMLDEYNMPPCIVVKSDGASIYATRDLAAASYRHKTY
NFDKCIYVVGKDQILHFNQVFKTLELAGNEWAKNCVHIPFGLVKFADRKLSTRKGNVVLLEDLLNEAIDKTRETIEEKNP
QLENKEEVAKKIGIGAILFTYLKNSRERDIVFDWKEMLSFDGETGPYVQYSYARAKSILRKAEEQKITAEPDFTKLTSKE
EFELAKTLEGLQKAVILGIDKLEPSVVTRYSIEVAKAFNKFYNNHTVLNVEDEGLKAARLELIKATAQVIKNALFLIGID
VVEKM
>Mature_565_residues
MDYKKLVAERIKEHVDLELENIEKLIEIPPKPEMGDFAFPCFQLAKVMRKAPNMIAAELAEKINKEGFERVECLGPYLNF
FVDKVAFSKNIISKVLEEGDKYGSSKIGEGKNVVVEYSSPNIAKPFHVGHLFTTAIGHSLYRMLNFEGYNPIRINHLGDW
GTQFGKLISAYKRWGNEEALEEAPINELLRIYVKFHDEAENNPELEDEGRMYFKKLEDGDQEAVALWERFKDLSLKEFNK
IYDMLGVDFDSWAGESFYNDKMDKVVEELEKANILTESNGAKVVMLDEYNMPPCIVVKSDGASIYATRDLAAASYRHKTY
NFDKCIYVVGKDQILHFNQVFKTLELAGNEWAKNCVHIPFGLVKFADRKLSTRKGNVVLLEDLLNEAIDKTRETIEEKNP
QLENKEEVAKKIGIGAILFTYLKNSRERDIVFDWKEMLSFDGETGPYVQYSYARAKSILRKAEEQKITAEPDFTKLTSKE
EFELAKTLEGLQKAVILGIDKLEPSVVTRYSIEVAKAFNKFYNNHTVLNVEDEGLKAARLELIKATAQVIKNALFLIGID
VVEKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI197100773, Length=589, Percent_Identity=33.955857385399, Blast_Score=321, Evalue=1e-87,
Organism=Homo sapiens, GI15149476, Length=574, Percent_Identity=31.184668989547, Blast_Score=236, Evalue=4e-62,
Organism=Escherichia coli, GI1788184, Length=587, Percent_Identity=33.5604770017036, Blast_Score=304, Evalue=8e-84,
Organism=Caenorhabditis elegans, GI71985061, Length=598, Percent_Identity=32.2742474916388, Blast_Score=232, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI71985068, Length=567, Percent_Identity=32.2751322751323, Blast_Score=226, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI17532153, Length=501, Percent_Identity=27.9441117764471, Blast_Score=159, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6320548, Length=557, Percent_Identity=37.342908438061, Blast_Score=350, Evalue=5e-97,
Organism=Saccharomyces cerevisiae, GI6321883, Length=549, Percent_Identity=35.3369763205829, Blast_Score=340, Evalue=4e-94,
Organism=Drosophila melanogaster, GI18859963, Length=542, Percent_Identity=33.0258302583026, Blast_Score=242, Evalue=6e-64,
Organism=Drosophila melanogaster, GI28571570, Length=468, Percent_Identity=31.8376068376068, Blast_Score=239, Evalue=3e-63,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_CLOPE (Q8XJU2)

Other databases:

- EMBL:   BA000016
- RefSeq:   NP_562577.1
- ProteinModelPortal:   Q8XJU2
- SMR:   Q8XJU2
- GeneID:   989971
- GenomeReviews:   BA000016_GR
- KEGG:   cpe:CPE1661
- NMPDR:   fig|195102.1.peg.1724
- HOGENOM:   HBG695395
- OMA:   AYKKWGN
- PhylomeDB:   Q8XJU2
- ProtClustDB:   PRK01611
- BioCyc:   CPER195102:CPE1661-MONOMER
- BRENDA:   6.1.1.19
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 64627; Mature: 64627

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00178 AA_TRNA_LIGASE_I; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYKKLVAERIKEHVDLELENIEKLIEIPPKPEMGDFAFPCFQLAKVMRKAPNMIAAELA
CCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
EKINKEGFERVECLGPYLNFFVDKVAFSKNIISKVLEEGDKYGSSKIGEGKNVVVEYSSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCC
NIAKPFHVGHLFTTAIGHSLYRMLNFEGYNPIRINHLGDWGTQFGKLISAYKRWGNEEAL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHH
EEAPINELLRIYVKFHDEAENNPELEDEGRMYFKKLEDGDQEAVALWERFKDLSLKEFNK
HHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHH
IYDMLGVDFDSWAGESFYNDKMDKVVEELEKANILTESNGAKVVMLDEYNMPPCIVVKSD
HHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHCCCEECCCCCEEEEEECCCCCCEEEEECC
GASIYATRDLAAASYRHKTYNFDKCIYVVGKDQILHFNQVFKTLELAGNEWAKNCVHIPF
CCEEEEEHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCHHHHCCEECCH
GLVKFADRKLSTRKGNVVLLEDLLNEAIDKTRETIEEKNPQLENKEEVAKKIGIGAILFT
HHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCHHHHHHH
YLKNSRERDIVFDWKEMLSFDGETGPYVQYSYARAKSILRKAEEQKITAEPDFTKLTSKE
HHHCCCCCCEEEEHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHH
EFELAKTLEGLQKAVILGIDKLEPSVVTRYSIEVAKAFNKFYNNHTVLNVEDEGLKAARL
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHH
ELIKATAQVIKNALFLIGIDVVEKM
HHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDYKKLVAERIKEHVDLELENIEKLIEIPPKPEMGDFAFPCFQLAKVMRKAPNMIAAELA
CCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
EKINKEGFERVECLGPYLNFFVDKVAFSKNIISKVLEEGDKYGSSKIGEGKNVVVEYSSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCC
NIAKPFHVGHLFTTAIGHSLYRMLNFEGYNPIRINHLGDWGTQFGKLISAYKRWGNEEAL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHH
EEAPINELLRIYVKFHDEAENNPELEDEGRMYFKKLEDGDQEAVALWERFKDLSLKEFNK
HHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHH
IYDMLGVDFDSWAGESFYNDKMDKVVEELEKANILTESNGAKVVMLDEYNMPPCIVVKSD
HHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHCCCEECCCCCEEEEEECCCCCCEEEEECC
GASIYATRDLAAASYRHKTYNFDKCIYVVGKDQILHFNQVFKTLELAGNEWAKNCVHIPF
CCEEEEEHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCHHHHCCEECCH
GLVKFADRKLSTRKGNVVLLEDLLNEAIDKTRETIEEKNPQLENKEEVAKKIGIGAILFT
HHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCHHHHHHH
YLKNSRERDIVFDWKEMLSFDGETGPYVQYSYARAKSILRKAEEQKITAEPDFTKLTSKE
HHHCCCCCCEEEEHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHH
EFELAKTLEGLQKAVILGIDKLEPSVVTRYSIEVAKAFNKFYNNHTVLNVEDEGLKAARL
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHH
ELIKATAQVIKNALFLIGIDVVEKM
HHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11792842