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The map label for this gene is msrB

Identifier: 18310589

GI number: 18310589

Start: 1879670

End: 1880113

Strand: Reverse

Name: msrB

Synonym: CPE1607

Alternate gene names: 18310589

Gene position: 1880113-1879670 (Counterclockwise)

Preceding gene: 18310590

Following gene: 18310588

Centisome position: 62.02

GC content: 30.63

Gene sequence:

>444_bases
TTGAAATATACAAAGAAGGAAAAAGAGGAATTAAAAAAAGTCTTAACTGAGGAAGAATATTATGTTACTCAAGAAAATGG
AACTGAAAGACCTTTTACAAATGAATATTGGGACTTTAATGGAGAAGGAATATATGTAGATATAACTACTGGAGAGCCTT
TATTTACTTCAAAGGATAAATTTCACTCTTCTTGTGGATGGCCTGCCTTTTCAAAACCAATAGATAGAAGCATAATAAAA
GAAAAGGTAGATAAAAGTCATGGAATGATTAGAACAGAAGTTAGAAGTAAACTAGGAGATTCACATTTAGGCCATGTGTT
TTGTGATGGACCAGAGGAGTTAGGTGGATTAAGATATTGCATAAATTCTGCTTCTTTAAAATTTATTCCAAAGGAAGAAT
TAAAGGAAAAGGGATATGAAGAATATTTAGAGCTTTTTAAATAG

Upstream 100 bases:

>100_bases
AAAAGATTATCTTGAAAGAATGTAAATATAACTCATTAAAATAATATTTTACATAAGTATTATTTTAAAATAATAATAAA
TAAAAAATGGAGTGATCATT

Downstream 100 bases:

>100_bases
AGTTAAGTATTTTAAAGATAAGGATATAATAAAGGAAATAGAAAAGTAGGTGTTTTAATGGGATTCTTATTAAACAATGA
TGGAGAAAATGATTTTCTTT

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MKYTKKEKEELKKVLTEEEYYVTQENGTERPFTNEYWDFNGEGIYVDITTGEPLFTSKDKFHSSCGWPAFSKPIDRSIIK
EKVDKSHGMIRTEVRSKLGDSHLGHVFCDGPEELGGLRYCINSASLKFIPKEELKEKGYEEYLELFK

Sequences:

>Translated_147_residues
MKYTKKEKEELKKVLTEEEYYVTQENGTERPFTNEYWDFNGEGIYVDITTGEPLFTSKDKFHSSCGWPAFSKPIDRSIIK
EKVDKSHGMIRTEVRSKLGDSHLGHVFCDGPEELGGLRYCINSASLKFIPKEELKEKGYEEYLELFK
>Mature_147_residues
MKYTKKEKEELKKVLTEEEYYVTQENGTERPFTNEYWDFNGEGIYVDITTGEPLFTSKDKFHSSCGWPAFSKPIDRSIIK
EKVDKSHGMIRTEVRSKLGDSHLGHVFCDGPEELGGLRYCINSASLKFIPKEELKEKGYEEYLELFK

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family

Homologues:

Organism=Homo sapiens, GI301336164, Length=127, Percent_Identity=45.6692913385827, Blast_Score=109, Evalue=7e-25,
Organism=Homo sapiens, GI301336162, Length=127, Percent_Identity=45.6692913385827, Blast_Score=109, Evalue=7e-25,
Organism=Homo sapiens, GI73089054, Length=127, Percent_Identity=45.6692913385827, Blast_Score=109, Evalue=7e-25,
Organism=Homo sapiens, GI37620216, Length=125, Percent_Identity=46.4, Blast_Score=109, Evalue=9e-25,
Organism=Homo sapiens, GI117606353, Length=132, Percent_Identity=43.9393939393939, Blast_Score=103, Evalue=7e-23,
Organism=Escherichia coli, GI1788077, Length=133, Percent_Identity=47.3684210526316, Blast_Score=123, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17553450, Length=128, Percent_Identity=50, Blast_Score=120, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI115532676, Length=128, Percent_Identity=50, Blast_Score=119, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6319816, Length=120, Percent_Identity=37.5, Blast_Score=77, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221378664, Length=123, Percent_Identity=48.780487804878, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI221378662, Length=131, Percent_Identity=45.8015267175573, Blast_Score=112, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24645799, Length=123, Percent_Identity=48.780487804878, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI45553335, Length=123, Percent_Identity=48.780487804878, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21356369, Length=123, Percent_Identity=48.780487804878, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24645801, Length=134, Percent_Identity=45.5223880597015, Blast_Score=106, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24645804, Length=134, Percent_Identity=45.5223880597015, Blast_Score=106, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSRB_CLOP1 (Q0TPZ6)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696294.1
- ProteinModelPortal:   Q0TPZ6
- SMR:   Q0TPZ6
- STRING:   Q0TPZ6
- GeneID:   4202592
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_1860
- TIGR:   CPF_1860
- eggNOG:   COG0229
- HOGENOM:   HBG715255
- OMA:   EPLFASA
- ProtClustDB:   PRK00222
- BioCyc:   CPER195103:CPF_1860-MONOMER
- HAMAP:   MF_01400
- InterPro:   IPR002579
- InterPro:   IPR011057
- Gene3D:   G3DSA:2.170.150.20
- TIGRFAMs:   TIGR00357

Pfam domain/function: PF01641 SelR; SSF51316 Mss4_like

EC number: =1.8.4.12

Molecular weight: Translated: 17118; Mature: 17118

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: ACT_SITE 120-120

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYTKKEKEELKKVLTEEEYYVTQENGTERPFTNEYWDFNGEGIYVDITTGEPLFTSKDK
CCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHH
FHSSCGWPAFSKPIDRSIIKEKVDKSHGMIRTEVRSKLGDSHLGHVFCDGPEELGGLRYC
HHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHH
INSASLKFIPKEELKEKGYEEYLELFK
HCCCCEEECCHHHHHHCCHHHHHHHHC
>Mature Secondary Structure
MKYTKKEKEELKKVLTEEEYYVTQENGTERPFTNEYWDFNGEGIYVDITTGEPLFTSKDK
CCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHH
FHSSCGWPAFSKPIDRSIIKEKVDKSHGMIRTEVRSKLGDSHLGHVFCDGPEELGGLRYC
HHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHH
INSASLKFIPKEELKEKGYEEYLELFK
HCCCCEEECCHHHHHHCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA