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The map label for this gene is bioD [H]

Identifier: 18310525

GI number: 18310525

Start: 1806187

End: 1806873

Strand: Reverse

Name: bioD [H]

Synonym: CPE1543

Alternate gene names: 18310525

Gene position: 1806873-1806187 (Counterclockwise)

Preceding gene: 18310526

Following gene: 18310524

Centisome position: 59.6

GC content: 27.37

Gene sequence:

>687_bases
ATGGAAAAGGGAGTATATATAATAGGAACTAATACTGATATTGGTAAAACCTTTATTAGTGGACTAATTTTAAAAAAGTT
AAGAGAAGAGGGAAGAAATGCAGGGTATTACAAGGCAGTTTTAAGTGGAGCTATAAAAGAGAAAAATGGATTAATACCTT
TAGATTGTGAAGAAGTTATGAAGATTTCTGGACTTAAGGAATCCTATGAAAATATGGTTTCTTACATACTAGAAAATCCA
TATTCTCCTCATTTAGCAAGTGAAGTAGAAGAAGTTTCTATAAGTATGGAAAAGATAAAAAAAGATTATAAGAGTGTTAG
AGATAAATATGACTTTATTCTTTGTGAAGGAAGTGGAGGAATAGTGTGTCCCATAAGTTTTTCAGAGAAAAAGCTTATGC
TAGAAGATATAATTAAAGAGTTTAATCTTCAAATAATACTAGTATCTAATAGTGGATTAGGTACTATTAATTACACTGTT
TTAACAGTAAGTTATTTAAGAAACTTAGGGCTAAAAGTAAAAGGAATAATACTTAATAAATTTAATAAAAGTGATATTAT
ACACAGAGATAATAAGAAGATAATCAAAGAACTAACAGGAGTAAATAATATTTCAACTGTGCCAAAGATAGAAGATATAG
AAAAGTATGATTTAAATGAACTTAATGAGGTGCTTTATGGAATTTAA

Upstream 100 bases:

>100_bases
CAAATGCTACTATAACAGGGAATTTATTAACTACATGTGGAAATAAGATAAAAGACGATAAAAGATTAATAGAGAATATT
GGGATGAGGATTTTTTAGTT

Downstream 100 bases:

>100_bases
AGAGGATTTAATTTAGAGGAATATATTAAATTTATGCTTTAATTAACTAAAAATGTATAGAAAATCTTTTAGGAGAATAA
GATAGTTTTGCTATCTTATT

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MEKGVYIIGTNTDIGKTFISGLILKKLREEGRNAGYYKAVLSGAIKEKNGLIPLDCEEVMKISGLKESYENMVSYILENP
YSPHLASEVEEVSISMEKIKKDYKSVRDKYDFILCEGSGGIVCPISFSEKKLMLEDIIKEFNLQIILVSNSGLGTINYTV
LTVSYLRNLGLKVKGIILNKFNKSDIIHRDNKKIIKELTGVNNISTVPKIEDIEKYDLNELNEVLYGI

Sequences:

>Translated_228_residues
MEKGVYIIGTNTDIGKTFISGLILKKLREEGRNAGYYKAVLSGAIKEKNGLIPLDCEEVMKISGLKESYENMVSYILENP
YSPHLASEVEEVSISMEKIKKDYKSVRDKYDFILCEGSGGIVCPISFSEKKLMLEDIIKEFNLQIILVSNSGLGTINYTV
LTVSYLRNLGLKVKGIILNKFNKSDIIHRDNKKIIKELTGVNNISTVPKIEDIEKYDLNELNEVLYGI
>Mature_228_residues
MEKGVYIIGTNTDIGKTFISGLILKKLREEGRNAGYYKAVLSGAIKEKNGLIPLDCEEVMKISGLKESYENMVSYILENP
YSPHLASEVEEVSISMEKIKKDYKSVRDKYDFILCEGSGGIVCPISFSEKKLMLEDIIKEFNLQIILVSNSGLGTINYTV
LTVSYLRNLGLKVKGIILNKFNKSDIIHRDNKKIIKELTGVNNISTVPKIEDIEKYDLNELNEVLYGI

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=212, Percent_Identity=26.4150943396226, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI87081944, Length=221, Percent_Identity=26.6968325791855, Blast_Score=69, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6324385, Length=189, Percent_Identity=31.7460317460317, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 25668; Mature: 25668

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKGVYIIGTNTDIGKTFISGLILKKLREEGRNAGYYKAVLSGAIKEKNGLIPLDCEEVM
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHH
KISGLKESYENMVSYILENPYSPHLASEVEEVSISMEKIKKDYKSVRDKYDFILCEGSGG
HHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCC
IVCPISFSEKKLMLEDIIKEFNLQIILVSNSGLGTINYTVLTVSYLRNLGLKVKGIILNK
EEEEECCCCHHHHHHHHHHHCCEEEEEEECCCCCEEHHHHHHHHHHHHCCCEEEEEEEEC
FNKSDIIHRDNKKIIKELTGVNNISTVPKIEDIEKYDLNELNEVLYGI
CCCCCCEECCCHHHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHCC
>Mature Secondary Structure
MEKGVYIIGTNTDIGKTFISGLILKKLREEGRNAGYYKAVLSGAIKEKNGLIPLDCEEVM
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHH
KISGLKESYENMVSYILENPYSPHLASEVEEVSISMEKIKKDYKSVRDKYDFILCEGSGG
HHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCC
IVCPISFSEKKLMLEDIIKEFNLQIILVSNSGLGTINYTVLTVSYLRNLGLKVKGIILNK
EEEEECCCCHHHHHHHHHHHCCEEEEEEECCCCCEEHHHHHHHHHHHHCCCEEEEEEEEC
FNKSDIIHRDNKKIIKELTGVNNISTVPKIEDIEKYDLNELNEVLYGI
CCCCCCEECCCHHHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA