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The map label for this gene is psuK [H]

Identifier: 18310464

GI number: 18310464

Start: 1737195

End: 1738160

Strand: Reverse

Name: psuK [H]

Synonym: CPE1482

Alternate gene names: 18310464

Gene position: 1738160-1737195 (Counterclockwise)

Preceding gene: 18310465

Following gene: 18310463

Centisome position: 57.34

GC content: 31.99

Gene sequence:

>966_bases
ATGAACTTAAGAAAAGAACCATATTTATTGGTATTTGGAGCTTCTGTAGTGGATGTGTTTGGATTTAGTAAGGCGAGTTA
TAGACCCTATAACTCAACACCAGGTCATGTAAAGATATCTTTTGGGGGCGTTTGTAGAAACATTGCTGAAAATATGGCAA
GAGTAGGCGTAAATACTAATTTTATGTCCATATTAGGTAATGATGAGCATGGAAAGAGTATAGTAGAGCACTCAAAGAAA
ATAGGATATCATATGGACGATTCTATGGTAATAGAAGGTGGAAGCACTCCAACTTACTTAGCTATTTTAGATGAAAATGG
TGAAATGGTTTCTGCTATTGCAGATATGAAAAGTATAGGAGCTATGAATACTGATTTCATAGATTCTAAAAGAGAAATCT
TTGAGAATGCTGAATATACAGTTTTAGATTCGGATAATCCAGAAATAATGGAATATTTATTAAAGAACTTTAAGGATAAA
ACTAACTTTATCTTAGATCCAGTATCAGCAGAAAAAGCAAGCTGGGTAAAACATCTTATAAAGGATTTCCATACAATAAA
ACCTAATAGACATGAAGCAGAAATATTAGCAGGTTTCCCTATAACAGATACAGATGACTTAATAAAGGCAAGTAATTATT
TCTTAGGTTTAGGAATTAAAAAGGTATTTATAAGTTTAGATGCTGACGGTATATTCTATAATGACGGTGTATCTTGCGGT
AAAATAAAGGCAACAGAAGTTGATGTTAAAAATGTTACAGGAGCAGGGGACTCTTTTGTAGCTGGATTAGGATACGGATA
TATGAATAAAATGCCTATAGAGGATATTGTTAAATTTGCTATGACTATGTCTAATATAACAATATCACATGAGGAAACAA
TTCATCCAGACATGGCTTTAGATACTGTTTTAGCTAAATTAGAGAAAACAACTTGGGAAGAAGAAAAATACGATTTAAAT
AAATAG

Upstream 100 bases:

>100_bases
AAGACTTAAAGACTGTGGATACATATATAATAGAGAAAATAATCAGTTTGTTGCTGAATAATTATAATTTATGTTTTTTA
AAATAGGGAGGATTAATTAA

Downstream 100 bases:

>100_bases
AATATAATATTTTGTATTTTCTTGTAGGCTTAAACTTTAATCCTACATAAATATATAAATGTGGTGAGGTGAGATTATGA
GTAAAAAAATAAAAAAAGGA

Product: sugar kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MNLRKEPYLLVFGASVVDVFGFSKASYRPYNSTPGHVKISFGGVCRNIAENMARVGVNTNFMSILGNDEHGKSIVEHSKK
IGYHMDDSMVIEGGSTPTYLAILDENGEMVSAIADMKSIGAMNTDFIDSKREIFENAEYTVLDSDNPEIMEYLLKNFKDK
TNFILDPVSAEKASWVKHLIKDFHTIKPNRHEAEILAGFPITDTDDLIKASNYFLGLGIKKVFISLDADGIFYNDGVSCG
KIKATEVDVKNVTGAGDSFVAGLGYGYMNKMPIEDIVKFAMTMSNITISHEETIHPDMALDTVLAKLEKTTWEEEKYDLN
K

Sequences:

>Translated_321_residues
MNLRKEPYLLVFGASVVDVFGFSKASYRPYNSTPGHVKISFGGVCRNIAENMARVGVNTNFMSILGNDEHGKSIVEHSKK
IGYHMDDSMVIEGGSTPTYLAILDENGEMVSAIADMKSIGAMNTDFIDSKREIFENAEYTVLDSDNPEIMEYLLKNFKDK
TNFILDPVSAEKASWVKHLIKDFHTIKPNRHEAEILAGFPITDTDDLIKASNYFLGLGIKKVFISLDADGIFYNDGVSCG
KIKATEVDVKNVTGAGDSFVAGLGYGYMNKMPIEDIVKFAMTMSNITISHEETIHPDMALDTVLAKLEKTTWEEEKYDLN
K
>Mature_321_residues
MNLRKEPYLLVFGASVVDVFGFSKASYRPYNSTPGHVKISFGGVCRNIAENMARVGVNTNFMSILGNDEHGKSIVEHSKK
IGYHMDDSMVIEGGSTPTYLAILDENGEMVSAIADMKSIGAMNTDFIDSKREIFENAEYTVLDSDNPEIMEYLLKNFKDK
TNFILDPVSAEKASWVKHLIKDFHTIKPNRHEAEILAGFPITDTDDLIKASNYFLGLGIKKVFISLDADGIFYNDGVSCG
KIKATEVDVKNVTGAGDSFVAGLGYGYMNKMPIEDIVKFAMTMSNITISHEETIHPDMALDTVLAKLEKTTWEEEKYDLN
K

Specific function: Catalyzes the phosphorylation of pseudouridine to pseudouridine 5'-phosphate (PsiMP) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788491, Length=311, Percent_Identity=33.7620578778135, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI1788484, Length=306, Percent_Identity=28.4313725490196, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1790193, Length=251, Percent_Identity=25.4980079681275, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788493, Length=121, Percent_Identity=33.8842975206612, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=312, Percent_Identity=23.7179487179487, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.83 [H]

Molecular weight: Translated: 35689; Mature: 35689

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRKEPYLLVFGASVVDVFGFSKASYRPYNSTPGHVKISFGGVCRNIAENMARVGVNTN
CCCCCCCEEEEECCHHHHHHCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCC
FMSILGNDEHGKSIVEHSKKIGYHMDDSMVIEGGSTPTYLAILDENGEMVSAIADMKSIG
EEEEECCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHC
AMNTDFIDSKREIFENAEYTVLDSDNPEIMEYLLKNFKDKTNFILDPVSAEKASWVKHLI
CCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHH
KDFHTIKPNRHEAEILAGFPITDTDDLIKASNYFLGLGIKKVFISLDADGIFYNDGVSCG
HHHHHCCCCCCCCEEEECCCCCCCHHHHHHCCEEEEECCEEEEEEECCCCEEECCCCCCC
KIKATEVDVKNVTGAGDSFVAGLGYGYMNKMPIEDIVKFAMTMSNITISHEETIHPDMAL
EEEEEEEEHHHCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCEEECCCCCCCCHHHH
DTVLAKLEKTTWEEEKYDLNK
HHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNLRKEPYLLVFGASVVDVFGFSKASYRPYNSTPGHVKISFGGVCRNIAENMARVGVNTN
CCCCCCCEEEEECCHHHHHHCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCC
FMSILGNDEHGKSIVEHSKKIGYHMDDSMVIEGGSTPTYLAILDENGEMVSAIADMKSIG
EEEEECCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHC
AMNTDFIDSKREIFENAEYTVLDSDNPEIMEYLLKNFKDKTNFILDPVSAEKASWVKHLI
CCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHH
KDFHTIKPNRHEAEILAGFPITDTDDLIKASNYFLGLGIKKVFISLDADGIFYNDGVSCG
HHHHHCCCCCCCCEEEECCCCCCCHHHHHHCCEEEEECCEEEEEEECCCCEEECCCCCCC
KIKATEVDVKNVTGAGDSFVAGLGYGYMNKMPIEDIVKFAMTMSNITISHEETIHPDMAL
EEEEEEEEHHHCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCEEECCCCCCCCHHHH
DTVLAKLEKTTWEEEKYDLNK
HHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 3076173 [H]