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The map label for this gene is norM [H]

Identifier: 18310441

GI number: 18310441

Start: 1715138

End: 1716529

Strand: Reverse

Name: norM [H]

Synonym: CPE1459

Alternate gene names: 18310441

Gene position: 1716529-1715138 (Counterclockwise)

Preceding gene: 18310442

Following gene: 18310440

Centisome position: 56.62

GC content: 31.18

Gene sequence:

>1392_bases
ATGGACAAGAGAATTGATTTAACCGAAGGAAAAATAACAAGCAACCTTATAAAACTTTCCATACCTATTATGGCTACCTC
TTTTATACAAATGGCTTATAACATGGCAGATATGATATGGGTTGGTAGAATAGGAAGTAATGCAGTGGCAGCTGTTGGAA
CAGCAGGATTCTTTCCTTGGCTTGGTATGGCCTTTGTAATGATTTCTAAGGTGGGAGCTGAGATAAAAGTAGCACAGAGC
TTAGGAAGAAATGATATAGATAGCACAAAGGATTATATAAAAAGTGCATTTCAAATAAATATTATACTAGCTATTATTTA
TTCAATAATATTACTTTTATTTAATAGTCAGTTAATAGGATTTTTTGACTTAGGTGATGCTGAAGTTATAAAAATGGCTA
AGACATATTTAATTGCAGTTGCTTTAGGAATGATATTTAACTTTTTAAATCCAGTATTTACAGCGGTATTTACTGGTTCA
GGAGATAGTAGAACTCCTTTTATAGCTAATACTATAGGATTAATTTTTAACATAGTTTTTGATCCAATATTAATTTTTGG
TATAGGAATATTCCCAGAGATGGGTGTACTAGGAGCTGCCTTGGCTACAGTTTTAGCTCAGGTTATAGTTACAGTTACAT
TTTTATATATAATGATAAAAAGTAAGGCTGAATACTTAAAAATAAATATCTTAAGTGGAATTAAAATAAATTGTATGAAA
ACTTTATTCCATATTGGATTACCGGCAGCACTTCAGAGTGGATTATTTACTATTTTTTCAATGTTTATAGGAAAAATAGT
TGCAGTGTTTGGCCCTGTTCCTATAGCTGTTCAAAAGGTGGGTTCACAGGTTGAAGCCATTGCATGGATGACAGCAGGTG
GAATATCTACGGCCTTAAGCACATTTGTTGGACAAAATTATGGAGCTGGAAAGCTAAAAAGAATAGTAAAGGGATTTAAT
ATAACTATGATAATTTCTCTTATAGTAGGAGTATTTGCTTCCTTAGTATTAATTTTCTTTGGAGAAGAGATATTTAGAAT
ATTTATACCAGAGGCACAAGCTATAGAACAAGGAACAGTTTATTTAAAGATACTTGGCTATTGTCAGATTCTTGTTTGCG
TAGAAATAACAACAACAGGAGCATTTAATGGATTAGGAAGAACTTATATACCATCAATAATAAGTATATTATTAACAGGA
GCAAGAATACCAATGGCTTATATTATGTGTAAACCTGAGTTCTTAGGATTAGAAGGTATTTGGTGGGCCATAAGTATAAC
AGGTGCTTTAAAAGGGGTAGTGGTATATGCAATATATAGATACTTATATAAGAAAAATAAACTTTTTAAAGTATATAAGA
ATGAAAATGGAGAGGAATGTATAAATATATAG

Upstream 100 bases:

>100_bases
AATTTAAATTATTATATATAAAATAATTTTATATATTTAGCTTATATAAAATATGAATTATAATGTGTGGGAATAATTTT
TTAGATACACAGGGGGAAAA

Downstream 100 bases:

>100_bases
CTTCTAAGTTATATATTTATGACTATATTTTAAAAATAAGGGGTTATATAAAAAAGATTAATAATAAAACTTACAAAGGG
TTTGAAGAGAAATCTAGTAA

Product: hypothetical protein

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MDKRIDLTEGKITSNLIKLSIPIMATSFIQMAYNMADMIWVGRIGSNAVAAVGTAGFFPWLGMAFVMISKVGAEIKVAQS
LGRNDIDSTKDYIKSAFQINIILAIIYSIILLLFNSQLIGFFDLGDAEVIKMAKTYLIAVALGMIFNFLNPVFTAVFTGS
GDSRTPFIANTIGLIFNIVFDPILIFGIGIFPEMGVLGAALATVLAQVIVTVTFLYIMIKSKAEYLKINILSGIKINCMK
TLFHIGLPAALQSGLFTIFSMFIGKIVAVFGPVPIAVQKVGSQVEAIAWMTAGGISTALSTFVGQNYGAGKLKRIVKGFN
ITMIISLIVGVFASLVLIFFGEEIFRIFIPEAQAIEQGTVYLKILGYCQILVCVEITTTGAFNGLGRTYIPSIISILLTG
ARIPMAYIMCKPEFLGLEGIWWAISITGALKGVVVYAIYRYLYKKNKLFKVYKNENGEECINI

Sequences:

>Translated_463_residues
MDKRIDLTEGKITSNLIKLSIPIMATSFIQMAYNMADMIWVGRIGSNAVAAVGTAGFFPWLGMAFVMISKVGAEIKVAQS
LGRNDIDSTKDYIKSAFQINIILAIIYSIILLLFNSQLIGFFDLGDAEVIKMAKTYLIAVALGMIFNFLNPVFTAVFTGS
GDSRTPFIANTIGLIFNIVFDPILIFGIGIFPEMGVLGAALATVLAQVIVTVTFLYIMIKSKAEYLKINILSGIKINCMK
TLFHIGLPAALQSGLFTIFSMFIGKIVAVFGPVPIAVQKVGSQVEAIAWMTAGGISTALSTFVGQNYGAGKLKRIVKGFN
ITMIISLIVGVFASLVLIFFGEEIFRIFIPEAQAIEQGTVYLKILGYCQILVCVEITTTGAFNGLGRTYIPSIISILLTG
ARIPMAYIMCKPEFLGLEGIWWAISITGALKGVVVYAIYRYLYKKNKLFKVYKNENGEECINI
>Mature_463_residues
MDKRIDLTEGKITSNLIKLSIPIMATSFIQMAYNMADMIWVGRIGSNAVAAVGTAGFFPWLGMAFVMISKVGAEIKVAQS
LGRNDIDSTKDYIKSAFQINIILAIIYSIILLLFNSQLIGFFDLGDAEVIKMAKTYLIAVALGMIFNFLNPVFTAVFTGS
GDSRTPFIANTIGLIFNIVFDPILIFGIGIFPEMGVLGAALATVLAQVIVTVTFLYIMIKSKAEYLKINILSGIKINCMK
TLFHIGLPAALQSGLFTIFSMFIGKIVAVFGPVPIAVQKVGSQVEAIAWMTAGGISTALSTFVGQNYGAGKLKRIVKGFN
ITMIISLIVGVFASLVLIFFGEEIFRIFIPEAQAIEQGTVYLKILGYCQILVCVEITTTGAFNGLGRTYIPSIISILLTG
ARIPMAYIMCKPEFLGLEGIWWAISITGALKGVVVYAIYRYLYKKNKLFKVYKNENGEECINI

Specific function: Multidrug efflux pump [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=463, Percent_Identity=22.8941684665227, Blast_Score=90, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 50482; Mature: 50482

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKRIDLTEGKITSNLIKLSIPIMATSFIQMAYNMADMIWVGRIGSNAVAAVGTAGFFPW
CCCCCCCCCCHHHHHHHEEEHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHCCHHHHHH
LGMAFVMISKVGAEIKVAQSLGRNDIDSTKDYIKSAFQINIILAIIYSIILLLFNSQLIG
HHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
FFDLGDAEVIKMAKTYLIAVALGMIFNFLNPVFTAVFTGSGDSRTPFIANTIGLIFNIVF
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHH
DPILIFGIGIFPEMGVLGAALATVLAQVIVTVTFLYIMIKSKAEYLKINILSGIKINCMK
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHH
TLFHIGLPAALQSGLFTIFSMFIGKIVAVFGPVPIAVQKVGSQVEAIAWMTAGGISTALS
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHCCHHHHHHH
TFVGQNYGAGKLKRIVKGFNITMIISLIVGVFASLVLIFFGEEIFRIFIPEAQAIEQGTV
HHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCH
YLKILGYCQILVCVEITTTGAFNGLGRTYIPSIISILLTGARIPMAYIMCKPEFLGLEGI
HHHHHHHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHCCCCCE
WWAISITGALKGVVVYAIYRYLYKKNKLFKVYKNENGEECINI
EEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHCCC
>Mature Secondary Structure
MDKRIDLTEGKITSNLIKLSIPIMATSFIQMAYNMADMIWVGRIGSNAVAAVGTAGFFPW
CCCCCCCCCCHHHHHHHEEEHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHCCHHHHHH
LGMAFVMISKVGAEIKVAQSLGRNDIDSTKDYIKSAFQINIILAIIYSIILLLFNSQLIG
HHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
FFDLGDAEVIKMAKTYLIAVALGMIFNFLNPVFTAVFTGSGDSRTPFIANTIGLIFNIVF
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHH
DPILIFGIGIFPEMGVLGAALATVLAQVIVTVTFLYIMIKSKAEYLKINILSGIKINCMK
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHH
TLFHIGLPAALQSGLFTIFSMFIGKIVAVFGPVPIAVQKVGSQVEAIAWMTAGGISTALS
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHCCHHHHHHH
TFVGQNYGAGKLKRIVKGFNITMIISLIVGVFASLVLIFFGEEIFRIFIPEAQAIEQGTV
HHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCH
YLKILGYCQILVCVEITTTGAFNGLGRTYIPSIISILLTGARIPMAYIMCKPEFLGLEGI
HHHHHHHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHCCCCCE
WWAISITGALKGVVVYAIYRYLYKKNKLFKVYKNENGEECINI
EEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]