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The map label for this gene is yfkE [H]

Identifier: 18310356

GI number: 18310356

Start: 1625522

End: 1626568

Strand: Reverse

Name: yfkE [H]

Synonym: CPE1374

Alternate gene names: 18310356

Gene position: 1626568-1625522 (Counterclockwise)

Preceding gene: 18310357

Following gene: 18310351

Centisome position: 53.66

GC content: 29.8

Gene sequence:

>1047_bases
ATGAAAATACTAAAATGGCTTTTAATATTTATTCCTATAAGTATTATAGGTGAATTTATGCATTTTTCTCCAACTCTTAT
GTTTGTATTATCTGCTTTGGCAATAGTTCCTTTAGCAGGTCTTATGGGAGAGGCAACAGAGGAAATATCATTTTATACTG
GACCAAAATTAGGTGGTTTTTTAAATGCTACTTTTGGGAATGCTACAGAACTTATAATTTCATTTTTTGCATTAAAAGAT
GGTTTGTTTGATGTGGTTAAAGCTTCTATTGCAGGTTCTGTAATAGGAAATATACTATTAGTTCTAGGTGCTAGCATGTT
AGCAGGAGGATTAAAATATAAAACACAAAGTTTCAATAAAAAAGTAATGGAAACTAGTTCAAGTATGTTATTATTTGCTG
TTATTGGATTAACAATTCCTGCTATATTTATGCATACAATAAAACCAGAATTTTTAAATACGAAATATGAAAGTTTAAGT
GTAATAGTTGCTGTAGTAATGTTTGCTATATACATATTAAGTTTAATATTCTCATTTTTCACTCATAAGGATATATATGC
AGTAGAACAAGATGAGGAAGATGGAGAAGCTAAATGGTCATTAAAAAAGGCCATAACAGTGCTTGTTGTAGCTACAGTAA
TAATTGCCATAGAAAGTGAATTTTTAGTTGGGGCAGTAGAACCAATGACAGAGACTCTTGGATTAAGTAAGCTTTTTGTA
GGTATAATATTAATTCCTATAATAGGTAATGCTGCAGAGCACAGCACTGCAATAATAATGGCAATGAAGAATAAAATGGA
TGTTTCAGTGGAAATAGCTATAGGATCAAGTCTGCAAGTTATTTTATTTGTGGCTCCAGTATTAATATTTTTAAGTCTTA
TATTTAAGCCTATGAGCATAATATTTAATGCTTTTGAATTAGTAGCTTTAATAGTTTCTGTACTTATAGCTAATAGAATT
GTTAATGATGGAGAATCAAATTGGCTTGAAGGGGTACAACTTTTAGCTGTTTACATAATAATAGCAGCTATGTTTATGAT
CGTTTAA

Upstream 100 bases:

>100_bases
ATATTTTAAATAGGCAAATTAAGAATAATTTGTTAAAATAGTTAACAAAAGTGATATAATTATCTTTAGTAAAATTTATT
TTATATATGGAGGACTAAAG

Downstream 100 bases:

>100_bases
ATTAAAAGATTAATTAAATAAAACAGGTAAATTTTAAAAAGTACTTATAAGATATAATTTCAAAAATTAAGAGGTTGCAT
ATATAATTAATAATAAAAAT

Product: calcium/proton exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MKILKWLLIFIPISIIGEFMHFSPTLMFVLSALAIVPLAGLMGEATEEISFYTGPKLGGFLNATFGNATELIISFFALKD
GLFDVVKASIAGSVIGNILLVLGASMLAGGLKYKTQSFNKKVMETSSSMLLFAVIGLTIPAIFMHTIKPEFLNTKYESLS
VIVAVVMFAIYILSLIFSFFTHKDIYAVEQDEEDGEAKWSLKKAITVLVVATVIIAIESEFLVGAVEPMTETLGLSKLFV
GIILIPIIGNAAEHSTAIIMAMKNKMDVSVEIAIGSSLQVILFVAPVLIFLSLIFKPMSIIFNAFELVALIVSVLIANRI
VNDGESNWLEGVQLLAVYIIIAAMFMIV

Sequences:

>Translated_348_residues
MKILKWLLIFIPISIIGEFMHFSPTLMFVLSALAIVPLAGLMGEATEEISFYTGPKLGGFLNATFGNATELIISFFALKD
GLFDVVKASIAGSVIGNILLVLGASMLAGGLKYKTQSFNKKVMETSSSMLLFAVIGLTIPAIFMHTIKPEFLNTKYESLS
VIVAVVMFAIYILSLIFSFFTHKDIYAVEQDEEDGEAKWSLKKAITVLVVATVIIAIESEFLVGAVEPMTETLGLSKLFV
GIILIPIIGNAAEHSTAIIMAMKNKMDVSVEIAIGSSLQVILFVAPVLIFLSLIFKPMSIIFNAFELVALIVSVLIANRI
VNDGESNWLEGVQLLAVYIIIAAMFMIV
>Mature_348_residues
MKILKWLLIFIPISIIGEFMHFSPTLMFVLSALAIVPLAGLMGEATEEISFYTGPKLGGFLNATFGNATELIISFFALKD
GLFDVVKASIAGSVIGNILLVLGASMLAGGLKYKTQSFNKKVMETSSSMLLFAVIGLTIPAIFMHTIKPEFLNTKYESLS
VIVAVVMFAIYILSLIFSFFTHKDIYAVEQDEEDGEAKWSLKKAITVLVVATVIIAIESEFLVGAVEPMTETLGLSKLFV
GIILIPIIGNAAEHSTAIIMAMKNKMDVSVEIAIGSSLQVILFVAPVLIFLSLIFKPMSIIFNAFELVALIVSVLIANRI
VNDGESNWLEGVQLLAVYIIIAAMFMIV

Specific function: Unknown

COG id: COG0387

COG function: function code P; Ca2+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320075, Length=356, Percent_Identity=42.4157303370786, Blast_Score=256, Evalue=4e-69,
Organism=Saccharomyces cerevisiae, GI6324008, Length=396, Percent_Identity=26.5151515151515, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004713
- InterPro:   IPR004798
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 37804; Mature: 37804

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILKWLLIFIPISIIGEFMHFSPTLMFVLSALAIVPLAGLMGEATEEISFYTGPKLGGF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCC
LNATFGNATELIISFFALKDGLFDVVKASIAGSVIGNILLVLGASMLAGGLKYKTQSFNK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KVMETSSSMLLFAVIGLTIPAIFMHTIKPEFLNTKYESLSVIVAVVMFAIYILSLIFSFF
HHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
THKDIYAVEQDEEDGEAKWSLKKAITVLVVATVIIAIESEFLVGAVEPMTETLGLSKLFV
HCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIILIPIIGNAAEHSTAIIMAMKNKMDVSVEIAIGSSLQVILFVAPVLIFLSLIFKPMSI
HHHHHHHCCCCCCCHHEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
IFNAFELVALIVSVLIANRIVNDGESNWLEGVQLLAVYIIIAAMFMIV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKILKWLLIFIPISIIGEFMHFSPTLMFVLSALAIVPLAGLMGEATEEISFYTGPKLGGF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCC
LNATFGNATELIISFFALKDGLFDVVKASIAGSVIGNILLVLGASMLAGGLKYKTQSFNK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KVMETSSSMLLFAVIGLTIPAIFMHTIKPEFLNTKYESLSVIVAVVMFAIYILSLIFSFF
HHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
THKDIYAVEQDEEDGEAKWSLKKAITVLVVATVIIAIESEFLVGAVEPMTETLGLSKLFV
HCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIILIPIIGNAAEHSTAIIMAMKNKMDVSVEIAIGSSLQVILFVAPVLIFLSLIFKPMSI
HHHHHHHCCCCCCCHHEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
IFNAFELVALIVSVLIANRIVNDGESNWLEGVQLLAVYIIIAAMFMIV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]