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The map label for this gene is prkA [H]

Identifier: 18310316

GI number: 18310316

Start: 1574621

End: 1576543

Strand: Reverse

Name: prkA [H]

Synonym: CPE1334

Alternate gene names: 18310316

Gene position: 1576543-1574621 (Counterclockwise)

Preceding gene: 18310317

Following gene: 18310315

Centisome position: 52.01

GC content: 29.49

Gene sequence:

>1923_bases
ATGGATTTTAAAGAGTTTATAAAAAGCGATAGGGAAAAACATAATAAGCAGAAGTTTAAGGGAACATTTCTTGATTATTT
AGAAATTGTAAAAAATAATCCTGATGTTGCAAAACTTTCTCATAAAAGGATTTATGATCTTATTATGGATAAGGGCTTTG
AAATATTAAGACCTGAGGAAAATGCAAAAATTAAAAAGATATATGGGAATGAAAAAATAAAGAGATATAACTTTTTTAAA
GAAGATTTTTATGGAATTGATACAGTTGTGATGAAATTAATGAATTATTTTCATTCGGCTTCAATGAGGGGAGAAGAAGC
AAGACAAGTATTATACTTAGTAGGACCTGTGGGAGCAGGTAAATCCTCTTTAGTAGAATCAATTAAAAGAGTTTTAGAAA
CAGCACCGCCAGTATATGTTTTAGATGGATGTCCTATGCATGAAGAGCCACTGCATTTAATACCTAAACATTTAAGAAAA
GAATTTGGGGATATGTTAGGTGTTGAGATTGAAGGAGATTTATGTCCAGTTTGTAAGTATAGATTATTAAATGAATTTGG
TGGAGAATATGAAAAGTTTCCAGTTTCAACAAAGAATTTTTCAATTCGTTCTAGAAAAGGAATTGGAGTTGTACCTCCAG
TAGATCCTAATAACCAAGATACCTCAATTTTAACAGGATCTATTGATATTTCTAAAATGGACATGTATCCAGAGGATGAT
CCAAGAATATTCTCATTAAACGGTGCATTTAATGTTGGTAATAGAGGGTTAGTTGAATTTATTGAAGTATTTAAAAATGA
TGTGGAATATTTACACACCATAATAACTGCAACTCAAGAAAAATCTATTCCTTCACCAGGTAAGGGATCAATGATTTATT
TTGATGGACTTATAATAGCTCACTCTAATGAAGCTGAGTGGAATAAATTTAAATCAGATCATACTAATGAAGCAATCTTA
GATAGAATAGTAAAAATTGAAGTTCCATATTGTTTAGAGCTTAGTGAAGAAATTAAAATTTATGAAAAAATATTAAAGAA
ATCTAATTTTGATGCTCATATAGCTCCTCATACTATGGAAATTGCTTCAATGTTTGCTATATTAACAAGATTACTTCCTT
CTATGAAAGTTGATCCAATTACTAAACTTAAACTTTATAATGGAGAGGAAATTGTTGAAAAGGGAACAACTAAGAGAATT
GATGTTTTAGAGTTAAAAGAAGAAGCTGGAACCATGGAAGGCATGAAGGGAATTTCAACAAGATTTATTATAAAGGCAAT
AGATAATGCTCTATCAAATGCAGAGCATAAGTGTATAAATCCATTAAGCGTTATGGAAAGTATAATAAAATCTGTTAAGG
ATATGGATATATCTCAAGAGGATAAGAAGAAATATTTAGGATATATTCAAGATACCATAAGAAAAGAATATAATAAGATT
CTTGAAAAAGAAATTACAAAGGCATTTATTCACTCTTTTAAGGAGCAAGCAGAAAGTTTATTTAATAATTATATAGATAA
TGCAGAGGCTTATGTAAATAAAACAAAACTTAAGGATTCTTCAACTAGTGAAGAGTTAGAGCCAGATGAAGAATTTATGA
GAAGCATAGAGGAACAAATAGGAATATCAGAATCTTCTTCCAAGGGATTTAGGGCAGATGTAACATCATATATGTTCTAT
ATAGTTAGAAGTGGCGGAAAAATGGACTATAGATCTTATGAACCACTAAAAGAAGCTATTGAAAAGAAACTAACAGCTTC
AGTTAAGGATTTATCAAGAATAATAACTAAATCTAGAGTAAGAGATAAAGATCAAGATAGAAAGTATAATTCAATGGTAA
ATCAAATGGAGAAAAATGGTTATTGTCCACATTGCTGCGATGTAATATTAAAATATGCAGCTAATAACCTATGGAAGGAT
TAA

Upstream 100 bases:

>100_bases
AAAGAAATTAGTTTTACTAATTTCTTTTTTGTTTTATAAGGATATTTTGTCATAGAACATAATAGATAGGGAATATATTT
AGGGTAAAGGAGGGATTACA

Downstream 100 bases:

>100_bases
AATATGGCCATATTTAGAGATCAAGCAGAAAACCATGTAGAACATGATAGATCTATAGAGGATAGAAGACGTCACAGGCA
GTTAGTAGAAAAATCTATTA

Product: serine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MDFKEFIKSDREKHNKQKFKGTFLDYLEIVKNNPDVAKLSHKRIYDLIMDKGFEILRPEENAKIKKIYGNEKIKRYNFFK
EDFYGIDTVVMKLMNYFHSASMRGEEARQVLYLVGPVGAGKSSLVESIKRVLETAPPVYVLDGCPMHEEPLHLIPKHLRK
EFGDMLGVEIEGDLCPVCKYRLLNEFGGEYEKFPVSTKNFSIRSRKGIGVVPPVDPNNQDTSILTGSIDISKMDMYPEDD
PRIFSLNGAFNVGNRGLVEFIEVFKNDVEYLHTIITATQEKSIPSPGKGSMIYFDGLIIAHSNEAEWNKFKSDHTNEAIL
DRIVKIEVPYCLELSEEIKIYEKILKKSNFDAHIAPHTMEIASMFAILTRLLPSMKVDPITKLKLYNGEEIVEKGTTKRI
DVLELKEEAGTMEGMKGISTRFIIKAIDNALSNAEHKCINPLSVMESIIKSVKDMDISQEDKKKYLGYIQDTIRKEYNKI
LEKEITKAFIHSFKEQAESLFNNYIDNAEAYVNKTKLKDSSTSEELEPDEEFMRSIEEQIGISESSSKGFRADVTSYMFY
IVRSGGKMDYRSYEPLKEAIEKKLTASVKDLSRIITKSRVRDKDQDRKYNSMVNQMEKNGYCPHCCDVILKYAANNLWKD

Sequences:

>Translated_640_residues
MDFKEFIKSDREKHNKQKFKGTFLDYLEIVKNNPDVAKLSHKRIYDLIMDKGFEILRPEENAKIKKIYGNEKIKRYNFFK
EDFYGIDTVVMKLMNYFHSASMRGEEARQVLYLVGPVGAGKSSLVESIKRVLETAPPVYVLDGCPMHEEPLHLIPKHLRK
EFGDMLGVEIEGDLCPVCKYRLLNEFGGEYEKFPVSTKNFSIRSRKGIGVVPPVDPNNQDTSILTGSIDISKMDMYPEDD
PRIFSLNGAFNVGNRGLVEFIEVFKNDVEYLHTIITATQEKSIPSPGKGSMIYFDGLIIAHSNEAEWNKFKSDHTNEAIL
DRIVKIEVPYCLELSEEIKIYEKILKKSNFDAHIAPHTMEIASMFAILTRLLPSMKVDPITKLKLYNGEEIVEKGTTKRI
DVLELKEEAGTMEGMKGISTRFIIKAIDNALSNAEHKCINPLSVMESIIKSVKDMDISQEDKKKYLGYIQDTIRKEYNKI
LEKEITKAFIHSFKEQAESLFNNYIDNAEAYVNKTKLKDSSTSEELEPDEEFMRSIEEQIGISESSSKGFRADVTSYMFY
IVRSGGKMDYRSYEPLKEAIEKKLTASVKDLSRIITKSRVRDKDQDRKYNSMVNQMEKNGYCPHCCDVILKYAANNLWKD
>Mature_640_residues
MDFKEFIKSDREKHNKQKFKGTFLDYLEIVKNNPDVAKLSHKRIYDLIMDKGFEILRPEENAKIKKIYGNEKIKRYNFFK
EDFYGIDTVVMKLMNYFHSASMRGEEARQVLYLVGPVGAGKSSLVESIKRVLETAPPVYVLDGCPMHEEPLHLIPKHLRK
EFGDMLGVEIEGDLCPVCKYRLLNEFGGEYEKFPVSTKNFSIRSRKGIGVVPPVDPNNQDTSILTGSIDISKMDMYPEDD
PRIFSLNGAFNVGNRGLVEFIEVFKNDVEYLHTIITATQEKSIPSPGKGSMIYFDGLIIAHSNEAEWNKFKSDHTNEAIL
DRIVKIEVPYCLELSEEIKIYEKILKKSNFDAHIAPHTMEIASMFAILTRLLPSMKVDPITKLKLYNGEEIVEKGTTKRI
DVLELKEEAGTMEGMKGISTRFIIKAIDNALSNAEHKCINPLSVMESIIKSVKDMDISQEDKKKYLGYIQDTIRKEYNKI
LEKEITKAFIHSFKEQAESLFNNYIDNAEAYVNKTKLKDSSTSEELEPDEEFMRSIEEQIGISESSSKGFRADVTSYMFY
IVRSGGKMDYRSYEPLKEAIEKKLTASVKDLSRIITKSRVRDKDQDRKYNSMVNQMEKNGYCPHCCDVILKYAANNLWKD

Specific function: Unknown

COG id: COG2766

COG function: function code T; Putative Ser protein kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prkA family [H]

Homologues:

Organism=Escherichia coli, GI1788083, Length=579, Percent_Identity=32.9879101899827, Blast_Score=319, Evalue=4e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013153
- InterPro:   IPR010650
- InterPro:   IPR016230 [H]

Pfam domain/function: PF08298 AAA_PrkA; PF06798 PrkA [H]

EC number: NA

Molecular weight: Translated: 73542; Mature: 73542

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFKEFIKSDREKHNKQKFKGTFLDYLEIVKNNPDVAKLSHKRIYDLIMDKGFEILRPEE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEECCCC
NAKIKKIYGNEKIKRYNFFKEDFYGIDTVVMKLMNYFHSASMRGEEARQVLYLVGPVGAG
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEEEECCCCCC
KSSLVESIKRVLETAPPVYVLDGCPMHEEPLHLIPKHLRKEFGDMLGVEIEGDLCPVCKY
HHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCHHHHH
RLLNEFGGEYEKFPVSTKNFSIRSRKGIGVVPPVDPNNQDTSILTGSIDISKMDMYPEDD
HHHHHHCCCHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCEEEEECCEEEEECCCCCCC
PRIFSLNGAFNVGNRGLVEFIEVFKNDVEYLHTIITATQEKSIPSPGKGSMIYFDGLIIA
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEE
HSNEAEWNKFKSDHTNEAILDRIVKIEVPYCLELSEEIKIYEKILKKSNFDAHIAPHTME
ECCCCHHHHHCCCCCCHHHHHHHHHCCCCHHHCHHHHHHHHHHHHHHCCCCCEECCHHHH
IASMFAILTRLLPSMKVDPITKLKLYNGEEIVEKGTTKRIDVLELKEEAGTMEGMKGIST
HHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHH
RFIIKAIDNALSNAEHKCINPLSVMESIIKSVKDMDISQEDKKKYLGYIQDTIRKEYNKI
HHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LEKEITKAFIHSFKEQAESLFNNYIDNAEAYVNKTKLKDSSTSEELEPDEEFMRSIEEQI
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
GISESSSKGFRADVTSYMFYIVRSGGKMDYRSYEPLKEAIEKKLTASVKDLSRIITKSRV
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDKDQDRKYNSMVNQMEKNGYCPHCCDVILKYAANNLWKD
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDFKEFIKSDREKHNKQKFKGTFLDYLEIVKNNPDVAKLSHKRIYDLIMDKGFEILRPEE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEECCCC
NAKIKKIYGNEKIKRYNFFKEDFYGIDTVVMKLMNYFHSASMRGEEARQVLYLVGPVGAG
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEEEECCCCCC
KSSLVESIKRVLETAPPVYVLDGCPMHEEPLHLIPKHLRKEFGDMLGVEIEGDLCPVCKY
HHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCHHHHH
RLLNEFGGEYEKFPVSTKNFSIRSRKGIGVVPPVDPNNQDTSILTGSIDISKMDMYPEDD
HHHHHHCCCHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCEEEEECCEEEEECCCCCCC
PRIFSLNGAFNVGNRGLVEFIEVFKNDVEYLHTIITATQEKSIPSPGKGSMIYFDGLIIA
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEE
HSNEAEWNKFKSDHTNEAILDRIVKIEVPYCLELSEEIKIYEKILKKSNFDAHIAPHTME
ECCCCHHHHHCCCCCCHHHHHHHHHCCCCHHHCHHHHHHHHHHHHHHCCCCCEECCHHHH
IASMFAILTRLLPSMKVDPITKLKLYNGEEIVEKGTTKRIDVLELKEEAGTMEGMKGIST
HHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHH
RFIIKAIDNALSNAEHKCINPLSVMESIIKSVKDMDISQEDKKKYLGYIQDTIRKEYNKI
HHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LEKEITKAFIHSFKEQAESLFNNYIDNAEAYVNKTKLKDSSTSEELEPDEEFMRSIEEQI
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
GISESSSKGFRADVTSYMFYIVRSGGKMDYRSYEPLKEAIEKKLTASVKDLSRIITKSRV
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDKDQDRKYNSMVNQMEKNGYCPHCCDVILKYAANNLWKD
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]