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The map label for this gene is potC [H]

Identifier: 18310253

GI number: 18310253

Start: 1491787

End: 1492569

Strand: Reverse

Name: potC [H]

Synonym: CPE1271

Alternate gene names: 18310253

Gene position: 1492569-1491787 (Counterclockwise)

Preceding gene: 18310254

Following gene: 18310252

Centisome position: 49.24

GC content: 30.52

Gene sequence:

>783_bases
GTGAAGAAGAGCAAAGTATTAACAACCTTCGTTGTTTTGGTTTATATATTTCTATTTGCACCGCTAGTAATTATTGCCAT
GACTAGTATAGGAACAGAAAATTATATAGCATTTCCTCCAAAAGGATTTAGTTTGCAATGGTTTATTACAGTATTTAAAT
CTGAGGCATTTATAAAAAGTATGGGGACAAGCTTCTTAATATCTACAGTATCTACATTATCAGCTTTGGTTATAGGAATG
CCAGCGGTTTATGGATTAAGTAGATATAACTTCAAAGGAAAAGATATTCTTAAGAGTTTCTTCTTTTCGCCTTTAATAGT
TCCTGGAATAGTAGTGGGATTCTCATTGTTTCAGTTTTTATTGGTAAAGATGAACTTATCAGTATATGCTAGTTTGTTTA
TTGGACATACTTTAATAATAATTCCTTACATCATAAGAGTTGTAGGATCAAGTTTAGAGGGCTTTGATTATTCTATAGAG
GAAGCAGCTATGAGCTTAGGATGTAAAAAATCACAAACTTTCTTTAAAGTAGTTTTACCAAATATAACATCAGGGGTAAT
GGCAGCATTTATGTTAGCTTTTATAAATTCATTTAACAATGTTCCAGTATCTATATTCCTAACTGGACCAGGAGTAAGCA
CACTACCTACAACCATGATGAACTATGTTGAATATAATTATGATCCAACAGTATCAGCTTTATCAGTAATCTTAATGATA
TTAACTATTGGAATTATGTACATATTAGAAAAAACATTAGGATTAAATAATTTTGCAGGATAG

Upstream 100 bases:

>100_bases
GCCGCAGTTGTAGCAACAATAATGATTGTAGTCACTTTAATAGTAATAAAGGGGATTAACTTCCTAGCATCAAGATTAGA
TAAGAGAGGGGTTTCTTAAA

Downstream 100 bases:

>100_bases
AATTTAAGTTAAAAATTTATTTGGAGGATGAAAACATGGATTTAATAAACCTACAGAATATAAATGTTTCTTATGATAAG
AAAAATAATATATTGGAAAA

Product: ABC transporter

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MKKSKVLTTFVVLVYIFLFAPLVIIAMTSIGTENYIAFPPKGFSLQWFITVFKSEAFIKSMGTSFLISTVSTLSALVIGM
PAVYGLSRYNFKGKDILKSFFFSPLIVPGIVVGFSLFQFLLVKMNLSVYASLFIGHTLIIIPYIIRVVGSSLEGFDYSIE
EAAMSLGCKKSQTFFKVVLPNITSGVMAAFMLAFINSFNNVPVSIFLTGPGVSTLPTTMMNYVEYNYDPTVSALSVILMI
LTIGIMYILEKTLGLNNFAG

Sequences:

>Translated_260_residues
MKKSKVLTTFVVLVYIFLFAPLVIIAMTSIGTENYIAFPPKGFSLQWFITVFKSEAFIKSMGTSFLISTVSTLSALVIGM
PAVYGLSRYNFKGKDILKSFFFSPLIVPGIVVGFSLFQFLLVKMNLSVYASLFIGHTLIIIPYIIRVVGSSLEGFDYSIE
EAAMSLGCKKSQTFFKVVLPNITSGVMAAFMLAFINSFNNVPVSIFLTGPGVSTLPTTMMNYVEYNYDPTVSALSVILMI
LTIGIMYILEKTLGLNNFAG
>Mature_260_residues
MKKSKVLTTFVVLVYIFLFAPLVIIAMTSIGTENYIAFPPKGFSLQWFITVFKSEAFIKSMGTSFLISTVSTLSALVIGM
PAVYGLSRYNFKGKDILKSFFFSPLIVPGIVVGFSLFQFLLVKMNLSVYASLFIGHTLIIIPYIIRVVGSSLEGFDYSIE
EAAMSLGCKKSQTFFKVVLPNITSGVMAAFMLAFINSFNNVPVSIFLTGPGVSTLPTTMMNYVEYNYDPTVSALSVILMI
LTIGIMYILEKTLGLNNFAG

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=221, Percent_Identity=29.8642533936652, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787714, Length=230, Percent_Identity=31.304347826087, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787081, Length=244, Percent_Identity=25.4098360655738, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788764, Length=178, Percent_Identity=28.6516853932584, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28576; Mature: 28576

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]