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The map label for this gene is cspL [H]

Identifier: 18310224

GI number: 18310224

Start: 1450066

End: 1450275

Strand: Direct

Name: cspL [H]

Synonym: CPE1242

Alternate gene names: 18310224

Gene position: 1450066-1450275 (Clockwise)

Preceding gene: 18310220

Following gene: 18310228

Centisome position: 47.83

GC content: 34.29

Gene sequence:

>210_bases
ATGAGTAGTAGAACTGGAATAGTAAAATGGTTTAATCAAGAGAAAGGCTATGGCTTTATTTCTTGTGATGAAGGTGATGA
TGTATTTGTACATATCTCACAAGTGAAGGAAAAAGGACCTGAAAAAGATTTACATGAAGGTGAAAGTGTTTCTTTTGATA
TAAGCGAAGGGGAAAAAGGCCCAATGGCTACTAATGTTCAAAAGCTATAA

Upstream 100 bases:

>100_bases
TTAAAATAAGAGTAAAATTTCTAAAAGAAATATGTTTAAATTTACTATTATATGAAATACTATTAGTGTTTAGACTTTTT
TAATTTAAGGAGATGTATTT

Downstream 100 bases:

>100_bases
AAACTAAGGCTTAAATTCCGTTAAGTTAAGAAGAGATTTAAATGTTTTAATAAATATTCCGAGTAAATTCACAATATAAT
TTATGGTGATTACTCGGAAT

Product: cold shock protein

Products: NA

Alternate protein names: CspL [H]

Number of amino acids: Translated: 69; Mature: 68

Protein sequence:

>69_residues
MSSRTGIVKWFNQEKGYGFISCDEGDDVFVHISQVKEKGPEKDLHEGESVSFDISEGEKGPMATNVQKL

Sequences:

>Translated_69_residues
MSSRTGIVKWFNQEKGYGFISCDEGDDVFVHISQVKEKGPEKDLHEGESVSFDISEGEKGPMATNVQKL
>Mature_68_residues
SSRTGIVKWFNQEKGYGFISCDEGDDVFVHISQVKEKGPEKDLHEGESVSFDISEGEKGPMATNVQKL

Specific function: Binds To And Stimulates The Transcription Of The CCAAT- Containing, Cold-Shock-Inducible Promoters Of The H-Ns And Gyra Proteins. Binds Also To The Inverted Repeat 5'-ATTGG-3'. [C]

COG id: COG1278

COG function: function code K; Cold shock proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CSD (cold-shock) domain [H]

Homologues:

Organism=Homo sapiens, GI34098946, Length=65, Percent_Identity=52.3076923076923, Blast_Score=64, Evalue=2e-11,
Organism=Homo sapiens, GI156415990, Length=65, Percent_Identity=53.8461538461538, Blast_Score=64, Evalue=3e-11,
Organism=Homo sapiens, GI224586884, Length=65, Percent_Identity=52.3076923076923, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1789979, Length=66, Percent_Identity=57.5757575757576, Blast_Score=73, Evalue=4e-15,
Organism=Escherichia coli, GI1786841, Length=70, Percent_Identity=51.4285714285714, Blast_Score=68, Evalue=1e-13,
Organism=Escherichia coli, GI2367114, Length=71, Percent_Identity=46.4788732394366, Blast_Score=66, Evalue=4e-13,
Organism=Escherichia coli, GI1788126, Length=70, Percent_Identity=48.5714285714286, Blast_Score=66, Evalue=4e-13,
Organism=Escherichia coli, GI1787839, Length=68, Percent_Identity=51.4705882352941, Blast_Score=66, Evalue=5e-13,
Organism=Escherichia coli, GI1787834, Length=71, Percent_Identity=49.2957746478873, Blast_Score=61, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019844
- InterPro:   IPR012156
- InterPro:   IPR011129
- InterPro:   IPR002059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00313 CSD [H]

EC number: NA

Molecular weight: Translated: 7678; Mature: 7546

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00352 COLD_SHOCK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRTGIVKWFNQEKGYGFISCDEGDDVFVHISQVKEKGPEKDLHEGESVSFDISEGEKG
CCCCCCEEEEECCCCCCEEEEECCCCEEEEEEEHHHCCCCCCCCCCCCCEEEECCCCCCC
PMATNVQKL
CCCCCCCCC
>Mature Secondary Structure 
SSRTGIVKWFNQEKGYGFISCDEGDDVFVHISQVKEKGPEKDLHEGESVSFDISEGEKG
CCCCCEEEEECCCCCCEEEEECCCCEEEEEEEHHHCCCCCCCCCCCCCEEEECCCCCCC
PMATNVQKL
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669; 9439003 [H]