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The map label for this gene is dinG [C]

Identifier: 18310179

GI number: 18310179

Start: 1398012

End: 1400357

Strand: Reverse

Name: dinG [C]

Synonym: CPE1197

Alternate gene names: 18310179

Gene position: 1400357-1398012 (Counterclockwise)

Preceding gene: 18310180

Following gene: 18310178

Centisome position: 46.19

GC content: 28.18

Gene sequence:

>2346_bases
GTGAAAAATGAATTAATAAAGATTTCTATAAGAAACTTAGTTGAATTTGTTTTAAGAAGAGGAAGTATAGATAGTCGTAT
AAAAGCATCTGTAAGAGCTTTAGAAGGAATAAAGGGACACAAGAAAATACAGAGTTCTTATTCTGAAAAGGATAGGGCTG
AAGTTACCTTAAAAGAGGATATTGACTTTGAAGATTTTACTTTAAGGGTAGAAGGTAGAGCAGATGGAATATTAGAGGAA
AATGAAAAAATAATTATTGATGAAATAAAAACTACTACAAAAAACGTAATGGATATAGATTATGATTTTAATGAATTGCA
TTGGGCTCAGGCTAAAGTATATGCTTATATATACAGCAAAGAGAAAAATTTAGACTCAATAATAGTCCAGTTAACGTATT
ACAATGTTGAAGATTTTGGAACAAAGTTTTTAAGGAAAGAATATAGTTTTCATGAACTTAGAGAGTTTTTCTATGATTTA
ATAGAAAAATATAAAGAATGGATACTTTTAGAGAAAAGATGGATAGACTTTAGAAATGATTCTATAGAGAATTTTAATTT
CCCTTTTAAGTCTTATAGGAAGGGACAGAGAGAACTAGCTATTAGAGTTTATAAATCTATTACAGAGGGGAAAAAATGTT
TTGCAGAAGCACCTACTGGCATTGGGAAAACAATGTCTACATTATTTCCTGCAGTAAAAGCTTTAGGAGCTAAGGAAACT
CAAAAAATTTTTTATATAACGGCTAAAACTACCACAAGAGAAATTGCAAATAATACTTTACGTATTATGAGAGAAAAAGG
ATTAAATCTAAGAAGTGTTAATATAACTGCAAAGGAAAAATGTTGCAAGATGGAAGAAAAAAAGTGTATTCCAGAATATT
GTCCTTATGCTAATGGATACTTTGATAGGGTTAATATTGCTTTAAAAGAAGCACTAAGGCATAAGGAAGAATATGATTTA
GAATATATAAACAAATTATCTAAGGAATATAATATTTGTCCCTTTGAATTTTCTCTTGAGCTAAGTAATTTTTGTGATGT
AGTAATATGTGATTATAATTATATATTTGATCCTCAGGCTTCTTTAAAGGGAATATTAGAAGGAAAAGCCAAGGATTATA
CAATTTTAATAGATGAAGCTCATAATCTTTTAGATAGGGGTAGAAGTATGTATTCTTCCAAAATATTTAAAGATGATTTT
TTAAAACTAAAAAGAGAATTTAAAAGTAAGGATAAGGGAATATATAACTCTTTAGATAGGGCTAATAAATATTTAATAGA
AAAAAGAAAGGTTTTAGAAAATTTAGAGACTAAAAGTCTTGTGGAAAAGGAAGAACCAAGTGATTTATATGGAATTTTAA
GAGGCTTTTTAGAAAAGGTAGATATTTATGAGAGTAAATCTAGTGAAGAGAATTCAAATCTTTTAGAGTTATATTTTAAT
GTGTATGAATTCTTAAATATATGTGGATATTATGGAGAGGATTTTACTACTTTATATAAGTTAGATGGAAACAACTTAGA
ATTATCAATTAACTGTTTAGATCCATCTAGAATACTTAAAAGCATAATGAATAGGTTTAAATCAGTTATAATATTTTCAG
CTACTCTTCTTCCTATGGAGTATTTTAAAGAACTTTATGGAGCACAGGAAGGAGATTATTCTGTTAATTTAACTTCTCCC
TTTGATTATAAAAATAAGCTTACTATAGTTGGAAAGGATGTATCAACAACCTATTCTAATAGAAAGAGAACTCTTCCTAA
AATAGTTAATTACATAATAGAATGTGCTAAAAGCAAGAGAGGTAACTATCTTGTATTTTTCCCTTCTTATGAATATATGT
GGATGGTTCATGAGGAAATTAAAAAAAGAGAAGTTGATTTTAGTTTAGTAGCTCAAGGGGATCATATGAATGAAGAGGAA
AAAGAAGAGTTTTTATCTTTATTTAAAGAAGGAGGAGAAAAAACACATCTTGGCTTAGCTGTTTTAGGTGGGCATTTTTC
AGAGGGCATAGATTTAACCTTAGATAAACTTATTGGAGTTATAATTATTGGAGTTGGTATGCCTAAAATTTGCTTAGAGA
GAGAAAGTATAAAAGAATATTATAACTCTATAGGTAAAAATGGTTTTGACTATGCCTATGTTTATCCTGGAATAATTAAG
GTGCTTCAAGCAGCGGGAAGATGTATAAGAACAGAAAAAGATAAGGGGGTAGTACTTTTATTAGATGATAGATACTTTAC
AAATAAATATAAGAGTCTACTTCCAAGAGAATGGTTTTTTAATATTTTAGTAGAAAGTGAAGAAGGAATTAAAAACACTT
GCGAAAATTTTTGGAAGGAAGTTTAA

Upstream 100 bases:

>100_bases
AAAAACAAAAAGTCTAGAGAAATTTAATCTTTCTAGGCTTTTTATTTTTATTAATTATGTGATAGAGTTTATATATACAC
AGTGAAAATGGGTGATTTAA

Downstream 100 bases:

>100_bases
AGAGGCTGCAAAAAATATAACAATAAACCTTATAAACATATTGAGAAAACAATATATTTCCATAGAAATTTTATTTACAC
TATTTATAAGGTTTACTAAA

Product: helicase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 781; Mature: 781

Protein sequence:

>781_residues
MKNELIKISIRNLVEFVLRRGSIDSRIKASVRALEGIKGHKKIQSSYSEKDRAEVTLKEDIDFEDFTLRVEGRADGILEE
NEKIIIDEIKTTTKNVMDIDYDFNELHWAQAKVYAYIYSKEKNLDSIIVQLTYYNVEDFGTKFLRKEYSFHELREFFYDL
IEKYKEWILLEKRWIDFRNDSIENFNFPFKSYRKGQRELAIRVYKSITEGKKCFAEAPTGIGKTMSTLFPAVKALGAKET
QKIFYITAKTTTREIANNTLRIMREKGLNLRSVNITAKEKCCKMEEKKCIPEYCPYANGYFDRVNIALKEALRHKEEYDL
EYINKLSKEYNICPFEFSLELSNFCDVVICDYNYIFDPQASLKGILEGKAKDYTILIDEAHNLLDRGRSMYSSKIFKDDF
LKLKREFKSKDKGIYNSLDRANKYLIEKRKVLENLETKSLVEKEEPSDLYGILRGFLEKVDIYESKSSEENSNLLELYFN
VYEFLNICGYYGEDFTTLYKLDGNNLELSINCLDPSRILKSIMNRFKSVIIFSATLLPMEYFKELYGAQEGDYSVNLTSP
FDYKNKLTIVGKDVSTTYSNRKRTLPKIVNYIIECAKSKRGNYLVFFPSYEYMWMVHEEIKKREVDFSLVAQGDHMNEEE
KEEFLSLFKEGGEKTHLGLAVLGGHFSEGIDLTLDKLIGVIIIGVGMPKICLERESIKEYYNSIGKNGFDYAYVYPGIIK
VLQAAGRCIRTEKDKGVVLLLDDRYFTNKYKSLLPREWFFNILVESEEGIKNTCENFWKEV

Sequences:

>Translated_781_residues
MKNELIKISIRNLVEFVLRRGSIDSRIKASVRALEGIKGHKKIQSSYSEKDRAEVTLKEDIDFEDFTLRVEGRADGILEE
NEKIIIDEIKTTTKNVMDIDYDFNELHWAQAKVYAYIYSKEKNLDSIIVQLTYYNVEDFGTKFLRKEYSFHELREFFYDL
IEKYKEWILLEKRWIDFRNDSIENFNFPFKSYRKGQRELAIRVYKSITEGKKCFAEAPTGIGKTMSTLFPAVKALGAKET
QKIFYITAKTTTREIANNTLRIMREKGLNLRSVNITAKEKCCKMEEKKCIPEYCPYANGYFDRVNIALKEALRHKEEYDL
EYINKLSKEYNICPFEFSLELSNFCDVVICDYNYIFDPQASLKGILEGKAKDYTILIDEAHNLLDRGRSMYSSKIFKDDF
LKLKREFKSKDKGIYNSLDRANKYLIEKRKVLENLETKSLVEKEEPSDLYGILRGFLEKVDIYESKSSEENSNLLELYFN
VYEFLNICGYYGEDFTTLYKLDGNNLELSINCLDPSRILKSIMNRFKSVIIFSATLLPMEYFKELYGAQEGDYSVNLTSP
FDYKNKLTIVGKDVSTTYSNRKRTLPKIVNYIIECAKSKRGNYLVFFPSYEYMWMVHEEIKKREVDFSLVAQGDHMNEEE
KEEFLSLFKEGGEKTHLGLAVLGGHFSEGIDLTLDKLIGVIIIGVGMPKICLERESIKEYYNSIGKNGFDYAYVYPGIIK
VLQAAGRCIRTEKDKGVVLLLDDRYFTNKYKSLLPREWFFNILVESEEGIKNTCENFWKEV
>Mature_781_residues
MKNELIKISIRNLVEFVLRRGSIDSRIKASVRALEGIKGHKKIQSSYSEKDRAEVTLKEDIDFEDFTLRVEGRADGILEE
NEKIIIDEIKTTTKNVMDIDYDFNELHWAQAKVYAYIYSKEKNLDSIIVQLTYYNVEDFGTKFLRKEYSFHELREFFYDL
IEKYKEWILLEKRWIDFRNDSIENFNFPFKSYRKGQRELAIRVYKSITEGKKCFAEAPTGIGKTMSTLFPAVKALGAKET
QKIFYITAKTTTREIANNTLRIMREKGLNLRSVNITAKEKCCKMEEKKCIPEYCPYANGYFDRVNIALKEALRHKEEYDL
EYINKLSKEYNICPFEFSLELSNFCDVVICDYNYIFDPQASLKGILEGKAKDYTILIDEAHNLLDRGRSMYSSKIFKDDF
LKLKREFKSKDKGIYNSLDRANKYLIEKRKVLENLETKSLVEKEEPSDLYGILRGFLEKVDIYESKSSEENSNLLELYFN
VYEFLNICGYYGEDFTTLYKLDGNNLELSINCLDPSRILKSIMNRFKSVIIFSATLLPMEYFKELYGAQEGDYSVNLTSP
FDYKNKLTIVGKDVSTTYSNRKRTLPKIVNYIIECAKSKRGNYLVFFPSYEYMWMVHEEIKKREVDFSLVAQGDHMNEEE
KEEFLSLFKEGGEKTHLGLAVLGGHFSEGIDLTLDKLIGVIIIGVGMPKICLERESIKEYYNSIGKNGFDYAYVYPGIIK
VLQAAGRCIRTEKDKGVVLLLDDRYFTNKYKSLLPREWFFNILVESEEGIKNTCENFWKEV

Specific function: Probable Helicase Involved In DNA Repair And Perhaps Also Replication. [C]

COG id: COG1199

COG function: function code KL; Rad3-related DNA helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI301897118, Length=273, Percent_Identity=23.4432234432234, Blast_Score=70, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6325249, Length=520, Percent_Identity=24.4230769230769, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6321019, Length=716, Percent_Identity=23.1843575418994, Blast_Score=95, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010614
- InterPro:   IPR014013
- InterPro:   IPR006555
- InterPro:   IPR001650 [H]

Pfam domain/function: PF06733 DEAD_2 [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 91353; Mature: 91353

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNELIKISIRNLVEFVLRRGSIDSRIKASVRALEGIKGHKKIQSSYSEKDRAEVTLKED
CCCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEECC
IDFEDFTLRVEGRADGILEENEKIIIDEIKTTTKNVMDIDYDFNELHWAQAKVYAYIYSK
CCCCCEEEEECCCCCCCCCCCCEEEEEHHHHHHCCCEEECCCCCHHHHHHHEEEEEEEEC
EKNLDSIIVQLTYYNVEDFGTKFLRKEYSFHELREFFYDLIEKYKEWILLEKRWIDFRND
CCCCCEEEEEEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SIENFNFPFKSYRKGQRELAIRVYKSITEGKKCFAEAPTGIGKTMSTLFPAVKALGAKET
CCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCC
QKIFYITAKTTTREIANNTLRIMREKGLNLRSVNITAKEKCCKMEEKKCIPEYCPYANGY
CEEEEEEECCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHCCHHHCCCHHHCCCCCCC
FDRVNIALKEALRHKEEYDLEYINKLSKEYNICPFEFSLELSNFCDVVICDYNYIFDPQA
HHHHHHHHHHHHHCCHHCCHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCEEECCCH
SLKGILEGKAKDYTILIDEAHNLLDRGRSMYSSKIFKDDFLKLKREFKSKDKGIYNSLDR
HHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ANKYLIEKRKVLENLETKSLVEKEEPSDLYGILRGFLEKVDIYESKSSEENSNLLELYFN
HHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
VYEFLNICGYYGEDFTTLYKLDGNNLELSINCLDPSRILKSIMNRFKSVIIFSATLLPME
HHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
YFKELYGAQEGDYSVNLTSPFDYKNKLTIVGKDVSTTYSNRKRTLPKIVNYIIECAKSKR
HHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCC
GNYLVFFPSYEYMWMVHEEIKKREVDFSLVAQGDHMNEEEKEEFLSLFKEGGEKTHLGLA
CCEEEEECCCCEEHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEE
VLGGHFSEGIDLTLDKLIGVIIIGVGMPKICLERESIKEYYNSIGKNGFDYAYVYPGIIK
EECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHH
VLQAAGRCIRTEKDKGVVLLLDDRYFTNKYKSLLPREWFFNILVESEEGIKNTCENFWKE
HHHHCCHHCCCCCCCCEEEEECCCHHHHHHHHHCCHHHHHHHEEECCCCHHHHHHHHHHC
V
C
>Mature Secondary Structure
MKNELIKISIRNLVEFVLRRGSIDSRIKASVRALEGIKGHKKIQSSYSEKDRAEVTLKED
CCCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEECC
IDFEDFTLRVEGRADGILEENEKIIIDEIKTTTKNVMDIDYDFNELHWAQAKVYAYIYSK
CCCCCEEEEECCCCCCCCCCCCEEEEEHHHHHHCCCEEECCCCCHHHHHHHEEEEEEEEC
EKNLDSIIVQLTYYNVEDFGTKFLRKEYSFHELREFFYDLIEKYKEWILLEKRWIDFRND
CCCCCEEEEEEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SIENFNFPFKSYRKGQRELAIRVYKSITEGKKCFAEAPTGIGKTMSTLFPAVKALGAKET
CCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCC
QKIFYITAKTTTREIANNTLRIMREKGLNLRSVNITAKEKCCKMEEKKCIPEYCPYANGY
CEEEEEEECCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHCCHHHCCCHHHCCCCCCC
FDRVNIALKEALRHKEEYDLEYINKLSKEYNICPFEFSLELSNFCDVVICDYNYIFDPQA
HHHHHHHHHHHHHCCHHCCHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCEEECCCH
SLKGILEGKAKDYTILIDEAHNLLDRGRSMYSSKIFKDDFLKLKREFKSKDKGIYNSLDR
HHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ANKYLIEKRKVLENLETKSLVEKEEPSDLYGILRGFLEKVDIYESKSSEENSNLLELYFN
HHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
VYEFLNICGYYGEDFTTLYKLDGNNLELSINCLDPSRILKSIMNRFKSVIIFSATLLPME
HHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
YFKELYGAQEGDYSVNLTSPFDYKNKLTIVGKDVSTTYSNRKRTLPKIVNYIIECAKSKR
HHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCC
GNYLVFFPSYEYMWMVHEEIKKREVDFSLVAQGDHMNEEEKEEFLSLFKEGGEKTHLGLA
CCEEEEECCCCEEHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEE
VLGGHFSEGIDLTLDKLIGVIIIGVGMPKICLERESIKEYYNSIGKNGFDYAYVYPGIIK
EECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHH
VLQAAGRCIRTEKDKGVVLLLDDRYFTNKYKSLLPREWFFNILVESEEGIKNTCENFWKE
HHHHCCHHCCCCCCCCEEEEECCCHHHHHHHHHCCHHHHHHHEEECCCCHHHHHHHHHHC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11029001 [H]